| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicole R Sullivan, James W Crane, Katerina J Damjanoska, Gonzalo A Carrasco, Deborah N D'Souza, Francisca Garcia, Louis D Van de Ka. Tandospirone activates neuroendocrine and ERK (MAP kinase) signaling pathways specifically through 5-HT1A receptor mechanisms in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 371. issue 1. 2005-07-11. PMID:15655673. |
tandospirone activates neuroendocrine and erk (map kinase) signaling pathways specifically through 5-ht1a receptor mechanisms in vivo. |
2005-07-11 |
2023-08-12 |
rat |
| J R Shingala, R Balarama. Antihypertensive effect of 5-HT1A agonist buspirone and 5-HT2B antagonists in experimentally induced hypertension in rats. Pharmacology. vol 73. issue 3. 2005-04-26. PMID:15539790. |
antihypertensive effect of 5-ht1a agonist buspirone and 5-ht2b antagonists in experimentally induced hypertension in rats. |
2005-04-26 |
2023-08-12 |
rat |
| J R Shingala, R Balarama. Antihypertensive effect of 5-HT1A agonist buspirone and 5-HT2B antagonists in experimentally induced hypertension in rats. Pharmacology. vol 73. issue 3. 2005-04-26. PMID:15539790. |
we investigated the antihypertensive effect of 5-ht1a agonist (buspirone) and 5-ht2b antagonists (sb204741 and sb200646) in deoxycorticosterone acetate (doca)-salt-induced hypertensive rats. |
2005-04-26 |
2023-08-12 |
rat |
| Josélia B Daher, Marielle D de Melo, Carlos R Tonuss. Evidence for a spinal serotonergic control of the peripheral inflammation in the rat. Life sciences. vol 76. issue 20. 2005-04-11. PMID:15748628. |
the 5-ht1a agonist buspirone and the 5-ht1b/1d agonist sumatriptan (0.1, 1.0 and 10 nmol) also inhibited paw edema. |
2005-04-11 |
2023-08-12 |
rat |
| Martin B Keller, Frank J L Ruwe, Cecile J J G Janssens, J M Ad Sitsen, Riitta Jokinen, Janusz Janczewsk. Relapse prevention with gepirone ER in outpatients with major depression. Journal of clinical psychopharmacology. vol 25. issue 1. 2005-04-08. PMID:15643103. |
to evaluate long-term efficacy and tolerability of the serotonin 5-ht1a receptor agonist, gepirone extended release (er), a multicenter, randomized, placebo-controlled relapse prevention study was performed in patients with recurrent major depression (dsm-iv criteria). |
2005-04-08 |
2023-08-12 |
Not clear |
| Fumihiko Yasun. [Hippocampal serotonin 1A receptor and memory function]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 106. issue 10. 2005-03-29. PMID:15669228. |
to interpret the pharmacological implications, we administered the 5-ht1a agonist tandospirone to subjects and investigated the effect of the stimulation of 5-ht1a receptors on cognitive function together with the neuroendocrinological response. |
2005-03-29 |
2023-08-12 |
human |
| J A Sattin, I S Logi. Buspirone challenge is not a valid probe of central 5-HT1A receptor function. Cephalalgia : an international journal of headache. vol 24. issue 6. 2005-01-25. PMID:15154863. |
buspirone challenge is not a valid probe of central 5-ht1a receptor function. |
2005-01-25 |
2023-08-12 |
Not clear |
| Bankole A Johnso. Role of the serotonergic system in the neurobiology of alcoholism: implications for treatment. CNS drugs. vol 18. issue 15. 2005-01-24. PMID:15581381. |
buspirone, a serotonin 5-ht1a partial agonist, does not appear to be an effective treatment for alcoholics without comorbid disease. |
2005-01-24 |
2023-08-12 |
Not clear |
| Digavalli V Sivarao, Kimberly Newberry, Nicholas J Lodg. Effect of the 5HT1A receptor partial agonist buspirone on colorectal distension-induced pseudoaffective and behavioral responses in the female Wistar rat. European journal of pharmacology. vol 494. issue 1. 2005-01-13. PMID:15194447. |
effect of the 5ht1a receptor partial agonist buspirone on colorectal distension-induced pseudoaffective and behavioral responses in the female wistar rat. |
2005-01-13 |
2023-08-12 |
rat |
| Young-Hoon Kim, Joo-Cheol Shim, Deanna L Kelly, Jeong-Goo Lee, Young-Soo Seo, Robert R Conle. Cortisol response to buspirone in extended abstinent alcoholics. Alcohol and alcoholism (Oxford, Oxfordshire). vol 39. issue 4. 2004-10-08. PMID:15208158. |
we evaluated cortisol response to buspirone in extended abstinent alcoholic patients to determine 5-ht1a receptor sensitivity in alcoholism. |
2004-10-08 |
2023-08-12 |
Not clear |
| Young-Hoon Kim, Joo-Cheol Shim, Deanna L Kelly, Jeong-Goo Lee, Young-Soo Seo, Robert R Conle. Cortisol response to buspirone in extended abstinent alcoholics. Alcohol and alcoholism (Oxford, Oxfordshire). vol 39. issue 4. 2004-10-08. PMID:15208158. |
our results show that cortisol response to buspirone was significantly decreased in alcoholic patients compared to normal controls, reflecting decreased 5-ht1a receptor sensitivity. |
2004-10-08 |
2023-08-12 |
Not clear |
| Mary J Druse, Nuzhath F Tajuddin, Roberta A Gillespie, Elizabeth Dickson, Mohammed Atieh, Constance A Pietrzak, Phong T L. The serotonin-1A agonist ipsapirone prevents ethanol-associated death of total rhombencephalic neurons and prevents the reduction of fetal serotonin neurons. Brain research. Developmental brain research. vol 150. issue 2. 2004-08-23. PMID:15158072. |
previously, this laboratory showed that in utero and in vitro ethanol exposure significantly reduces developing serotonin (5-ht) neurons and that treatment with a 5-ht1a agonist such as buspirone or ipsapirone prevents the ethanol-associated loss. |
2004-08-23 |
2023-08-12 |
Not clear |
| Masafumi Ogaw. Pharmacological treatments of cerebellar ataxia. Cerebellum (London, England). vol 3. issue 2. 2004-08-23. PMID:15233578. |
in a double-blind randomized study, buspirone, a 5-ht1a agonist was active in cerebellar ataxia, but the effect is partial and not major. |
2004-08-23 |
2023-08-12 |
Not clear |
| I S Ebenezer, R M Tit. Differential effects of the 5-HT1A agonist gepirone on food intake in rats may depend on their motivation to eat. Methods and findings in experimental and clinical pharmacology. vol 25. issue 9. 2004-08-20. PMID:14685301. |
differential effects of the 5-ht1a agonist gepirone on food intake in rats may depend on their motivation to eat. |
2004-08-20 |
2023-08-12 |
rat |
| I S Ebenezer, R M Tit. Differential effects of the 5-HT1A agonist gepirone on food intake in rats may depend on their motivation to eat. Methods and findings in experimental and clinical pharmacology. vol 25. issue 9. 2004-08-20. PMID:14685301. |
the present study was therefore conducted to investigate a possible relationship between the effects of the 5ht1a agonist gepirone on food intake in rats and their motivation to eat. |
2004-08-20 |
2023-08-12 |
rat |
| Joshua G Lisinicchia, Val J Watt. Sensitization of adenylate cyclase by short-term activation of 5-HT1A receptors. Cellular signalling. vol 15. issue 12. 2004-07-13. PMID:14575866. |
short-term activation of 5-ht1a receptors with full agonists, as well as the partial agonist, buspirone, markedly enhanced subsequent forskolin-stimulated cyclic amp accumulation. |
2004-07-13 |
2023-08-12 |
Not clear |
| Patrick Osei-Owusu, Karie E Scrogi. Buspirone raises blood pressure through activation of sympathetic nervous system and by direct activation of alpha1-adrenergic receptors after severe hemorrhage. The Journal of pharmacology and experimental therapeutics. vol 309. issue 3. 2004-07-01. PMID:14769835. |
to determine whether 5-ht1a receptor-mediated pressor responses in hypovolemic animals are due to sympathoexcitation and/or direct vasoconstriction, blood pressure (bp), heart rate (hr), and renal sympathetic nerve activity (rsna) responses to the partial 5-ht1a receptor agonist buspirone or the more selective, full 5-ht1a receptor agonist (+)-8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) were compared in intact and ganglionic blocked, hemorrhaged sprague-dawley rats. |
2004-07-01 |
2023-08-12 |
rat |
| Asako Takei, Toshiyuki Fukazawa, Takeshi Hamada, Hiroyuki Sohma, Ichiro Yabe, Hidenao Sasaki, Kunio Tashir. Effects of tandospirone on "5-HT1A receptor-associated symptoms" in patients with Machado-Josephe disease: an open-label study. Clinical neuropharmacology. vol 27. issue 1. 2004-06-01. PMID:15090930. |
effects of tandospirone on "5-ht1a receptor-associated symptoms" in patients with machado-josephe disease: an open-label study. |
2004-06-01 |
2023-08-12 |
Not clear |
| Asako Takei, Toshiyuki Fukazawa, Takeshi Hamada, Hiroyuki Sohma, Ichiro Yabe, Hidenao Sasaki, Kunio Tashir. Effects of tandospirone on "5-HT1A receptor-associated symptoms" in patients with Machado-Josephe disease: an open-label study. Clinical neuropharmacology. vol 27. issue 1. 2004-06-01. PMID:15090930. |
we investigated the frequencies of the symptoms such as "ataxia, depression, insomnia, anorexia, and pain," that have been reported to be associated with 5-ht1a receptor, and the effect of tandospirone citrate (tandospirone: 5-ht1a agonist) in patients with machado-joseph disease (mjd). |
2004-06-01 |
2023-08-12 |
Not clear |
| E F Carvalho-Netto, R L Nunes-de-Souz. Use of the elevated T-maze to study anxiety in mice. Behavioural brain research. vol 148. issue 1-2. 2004-03-01. PMID:14684253. |
the 5-ht1a partial receptor agonist buspirone (1.0-2.0 mg/kg) and the 5-ht releaser fenfluramine (0.15-0.30 mg/kg) impaired iaa and facilitated escape, while the full 5-ht1a receptor agonist, 8-oh-dpat (0.05-0.1 mg/kg) and the 5-ht(2b/2c) receptor antagonist, ser 082 (0.5-2.0 mg/kg) failed to modify either response. |
2004-03-01 |
2023-08-12 |
mouse |