All Relations between 5-ht receptor 1a and Azapirones

Publication Sentence Publish Date Extraction Date Species
S P Jaw, T Dang, D D Truon. Chronic treatments with 5-HT1A agonists attenuate posthypoxic myoclonus in rats. Pharmacology, biochemistry, and behavior. vol 52. issue 3. 1996-02-14. PMID:8545477. single injections of 5-ht1a agonists, buspirone (5 and 10 mg/kg body wt.) 1996-02-14 2023-08-12 rat
M J Detke, M Rickels, I Luck. Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology. vol 121. issue 1. 1996-02-07. PMID:8539342. the 5-ht1a receptor agonists 8-oh-dpat and gepirone also selectively increased swimming. 1996-02-07 2023-08-12 rat
B K Koe, L A Lebe. Effects of serotoninergic agents on downregulation of beta-adrenoceptors by the selective serotonin reuptake inhibitor sertraline. Archives internationales de pharmacodynamie et de therapie. vol 329. issue 2. 1996-02-06. PMID:8540763. in a similar manner, the 5-ht1a agonists, gepirone and 8-oh-dpat, were found to facilitate the downregulation of beta-adrenoceptors induced by sertraline. 1996-02-06 2023-08-12 rat
C Sánche. Serotonergic mechanisms involved in the exploratory behaviour of mice in a fully automated two-compartment black and white text box. Pharmacology & toxicology. vol 77. issue 1. 1996-01-29. PMID:8532615. the partial 5-ht1a receptor agonists, buspirone and ipsapirone showed anxiolytic-like effects in a limited dose interval. 1996-01-29 2023-08-12 mouse
H Chen, L Zhang, D R Rubinow, D M Chuan. Chronic buspirone treatment differentially regulates 5-HT1A and 5-HT2A receptor mRNA and binding sites in various regions of the rat hippocampus. Brain research. Molecular brain research. vol 32. issue 2. 1996-01-18. PMID:7500848. chronic buspirone treatment differentially regulates 5-ht1a and 5-ht2a receptor mrna and binding sites in various regions of the rat hippocampus. 1996-01-18 2023-08-12 rat
H Chen, L Zhang, D R Rubinow, D M Chuan. Chronic buspirone treatment differentially regulates 5-HT1A and 5-HT2A receptor mRNA and binding sites in various regions of the rat hippocampus. Brain research. Molecular brain research. vol 32. issue 2. 1996-01-18. PMID:7500848. after buspirone treatment, the 5-ht1a receptor mrna levels were significantly decreased in the ca1 and ca2 of the hippocampus, but were markedly increased in the dentate gyrus (dg), ca3 and ca4. 1996-01-18 2023-08-12 rat
H Chen, L Zhang, D R Rubinow, D M Chuan. Chronic buspirone treatment differentially regulates 5-HT1A and 5-HT2A receptor mRNA and binding sites in various regions of the rat hippocampus. Brain research. Molecular brain research. vol 32. issue 2. 1996-01-18. PMID:7500848. these results demonstrate that chronic buspirone treatment differentially regulates 5-ht1a and 5-ht2a receptor mrna as well as their expressed binding sites in various regions of the hippocampus. 1996-01-18 2023-08-12 rat
M Suzuki, T Matsuda, S Asano, P Somboonthum, K Takuma, A Bab. Increase of noradrenaline release in the hypothalamus of freely moving rat by postsynaptic 5-hydroxytryptamine1A receptor activation. British journal of pharmacology. vol 115. issue 4. 1995-11-30. PMID:7582494. the 5-ht1a receptor agonists, 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat) (0.2 mg kg-1) and buspirone (3 mg kg-1) mimicked the effect of mkc-242 in increasing na release in the hypothalamus. 1995-11-30 2023-08-12 rat
U Freo, P Pietrini, G Pizzolato, M Furey-Kurkjian, A Merico, S Ruggero, M Dam, L Battisti. Dose-dependent effects of buspirone on behavior and cerebral glucose metabolism in rats. Brain research. vol 677. issue 2. 1995-11-14. PMID:7552245. these were the only rcmrglc effects buspirone had in common with the potent 5-ht1a agonist dpat and suggest that low dose buspirone activates preferentially 5-ht1a receptors. 1995-11-14 2023-08-12 rat
U Freo, P Pietrini, G Pizzolato, M Furey-Kurkjian, A Merico, S Ruggero, M Dam, L Battisti. Dose-dependent effects of buspirone on behavior and cerebral glucose metabolism in rats. Brain research. vol 677. issue 2. 1995-11-14. PMID:7552245. the topographic distribution and direction of rcmrglc changes by high doses of buspirone differ from those produced by the 5-ht1a agonist dpat. 1995-11-14 2023-08-12 rat
T Jaros, W Kolasiewic. Attenuation of the fentanyl-induced muscle rigidity by the selective 5HT1A agonist 8-OH-DPAT. Polish journal of pharmacology. vol 47. issue 1. 1995-11-09. PMID:7550544. these results seem to be clinically important in case other 5ht1a agonists, buspirone or gepirone (potent anxiolytics), also prevented fentanyl-induced muscle rigidity in humans. 1995-11-09 2023-08-12 rat
A B Alfieri, L X Cubedd. Comparative efficacy of a single oral dose of ondansetron and of buspirone against cisplatin-induced emesis in cancer patients. British journal of cancer. vol 72. issue 4. 1995-11-08. PMID:7547213. buspirone, an agonist of the 5-ht1a subtype of serotonin receptors, has shown antiemetic activity in animal models. 1995-11-08 2023-08-12 Not clear
M Freire-Garabal, M J Nů nez-Iglesias, J L Balboa, J C Fernåndez-Rial, M Rey-Mende. Effects of buspirone on the immune response to stress in mice. Pharmacology, biochemistry, and behavior. vol 51. issue 4. 1995-10-19. PMID:7675864. several experiments were conducted to evaluate the effects of buspirone, a selective 5-hydroxytryptamine-1a (5-ht1a) anxiolytic, on the immune system of mice exposed to a chronic auditory stressor. 1995-10-19 2023-08-12 mouse
M J Detke, S Wieland, I Luck. Blockade of the antidepressant-like effects of 8-OH-DPAT, buspirone and desipramine in the rat forced swim test by 5HT1A receptor antagonists. Psychopharmacology. vol 119. issue 1. 1995-10-19. PMID:7675949. blockade of the antidepressant-like effects of 8-oh-dpat, buspirone and desipramine in the rat forced swim test by 5ht1a receptor antagonists. 1995-10-19 2023-08-12 rat
M J Detke, S Wieland, I Luck. Blockade of the antidepressant-like effects of 8-OH-DPAT, buspirone and desipramine in the rat forced swim test by 5HT1A receptor antagonists. Psychopharmacology. vol 119. issue 1. 1995-10-19. PMID:7675949. the 5-ht1a receptor agonists 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat) and buspirone decreased immobility in the fst. 1995-10-19 2023-08-12 rat
R Schreiber, M Brocco, B L de Ladonchamps, M J Milla. Involvement of 5-HT1A receptors in the anxiolytic action of S 14671 in the pigeon conflict test. Pharmacology, biochemistry, and behavior. vol 51. issue 2-3. 1995-10-11. PMID:7667330. in contrast, the arylpiperazine 5-ht1a receptor agonists, ly 165,163 and tandospirone, increased punished responding only at higher doses (med: 0.16 and 0.63 mg/kg, respectively), and also with a lesser maximal effect (2065% and 3695%, respectively). 1995-10-11 2023-08-12 pigeon
R Schreiber, M Brocco, B L de Ladonchamps, M J Milla. Involvement of 5-HT1A receptors in the anxiolytic action of S 14671 in the pigeon conflict test. Pharmacology, biochemistry, and behavior. vol 51. issue 2-3. 1995-10-11. PMID:7667330. further, a correlation analysis across each of the above agonists, as well as 8-oh-dpat, buspirone, and (+)-flesinoxan, revealed a significant correlation for their relative potency in augmenting punished responding and their affinity for 5-ht1a receptors in vitro (r = +0.95, p < 0.001). 1995-10-11 2023-08-12 pigeon
G Griebel, D C Blanchard, A Jung, C K Masuda, R J Blanchar. 5-HT1A agonists modulate mouse antipredator defensive behavior differently from the 5-HT2A antagonist pirenperone. Pharmacology, biochemistry, and behavior. vol 51. issue 2-3. 1995-10-11. PMID:7667334. the present study evaluated the ability of 8-oh-dpat (0.05-10 mg/kg, sc, 5) and gepirone (2.5-10 mg/kg, ip, 30), a full- and a partial agonist at 5-ht1a sites, as well as pirenperone (0.25-1 mg/kg, ip, 30), a preferential 5-ht2a receptor antagonist, to exert an anxiolytic-like action in the mdtb. 1995-10-11 2023-08-12 mouse
T Croci, M Landi, A Bianchetti, L Manar. Drug-induced defaecation in rats: role of central 5-HT1A receptors. British journal of pharmacology. vol 115. issue 1. 1995-09-26. PMID:7647978. we investigated the acute effects of 5-hydroxytryptamine (5-ht), and of the 5-ht1a receptor agonists, 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat), buspirone and sr 57746a, on rat faecal pellet output and water content. 1995-09-26 2023-08-12 rat
T Croci, M Landi, A Bianchetti, L Manar. Drug-induced defaecation in rats: role of central 5-HT1A receptors. British journal of pharmacology. vol 115. issue 1. 1995-09-26. PMID:7647978. 5-ht, 8-oh-dpat, buspirone and sr 57746a, a new selective 5-ht1a receptor agonist, displaced [3h]-8-oh-dpat from specific binding sites in rat hippocampus membranes (ki, nm; 1.8, 1.2, 15, 3.1 respectively) and stimulated rat defaecation dose-dependently. 1995-09-26 2023-08-12 rat