| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M T Peña-Rangel, R Mercado, J Hernández-Rodrígue. Regulation of glial Na+/K+-ATPase by serotonin: identification of participating receptors. Neurochemical research. vol 24. issue 5. 1999-07-01. PMID:10344593. |
spiperone, a 5-ht1a antagonist, completely inhibited the response to 8-oh-dpat but had no effect on na+/k+-atpase activity in cerebellum where lsd, a 5-ht6 agonist, elicited a dose-dependent response similar to that of 5-ht. |
1999-07-01 |
2023-08-12 |
rat |
| Y F Liu, M H Ghahremani, M M Rasenick, K H Jakobs, P R Alber. Stimulation of cAMP synthesis by Gi-coupled receptors upon ablation of distinct Galphai protein expression. Gi subtype specificity of the 5-HT1A receptor. The Journal of biological chemistry. vol 274. issue 23. 1999-07-01. PMID:10347206. |
by contrast, receptor-mediated inhibition of vasoactive intestinal peptide (vip)-stimulated camp production was blocked by selective depletions for responses induced by the transfected serotonin 1a (5-ht1a) (galphai2 or galphai3) or endogenous muscarinic-m4 (galphai1 or galphai2) receptors. |
1999-07-01 |
2023-08-12 |
rat |
| M Franklin, R D Craven, B Dowling, G Campling, J M Elliott, P J Cowe. Effect of a long-term low tryptophan diet on the prolactin responses to the 5-HT1A and 5-HT2C agonists, 8-OH-DPAT and mCPP in the male rat. Journal of psychopharmacology (Oxford, England). vol 13. issue 1. 1999-06-28. PMID:10221360. |
the small or transient changes brought about by long-term trp depletion on post-synaptic 5-ht1a receptors, suggests that these receptors may be less susceptible to 5-ht depleting effects than the 5-ht2c subtype. |
1999-06-28 |
2023-08-12 |
rat |
| S M Stah. Mechanism of action of serotonin selective reuptake inhibitors. Serotonin receptors and pathways mediate therapeutic effects and side effects. Journal of affective disorders. vol 51. issue 3. 1999-06-28. PMID:10333979. |
the hypothesis to explain why ssris have such diverse therapeutic actions is that somatodendritic 5ht1a autoreceptor desensitization increases serotonin in those critical brain regions and at those key serotonin receptor subtype(s) which may mediate the pathophysiologies of the various disorders. |
1999-06-28 |
2023-08-12 |
Not clear |
| N Haddjeri, P Blier, C de Montign. Acute and long-term actions of the antidepressant drug mirtazapine on central 5-HT neurotransmission. Journal of affective disorders. vol 51. issue 3. 1999-06-28. PMID:10333981. |
these modifications of 5-ht neurons lead to an increased tonic activation of postsynaptic 5-ht1a receptors. |
1999-06-28 |
2023-08-12 |
rat |
| M L Wadenberg, K A Young, J T Richter, P B Hick. Effects of local application of 5-hydroxytryptamine into the dorsal or median raphe nuclei on haloperidol-induced catalepsy in the rat. Neuropharmacology. vol 38. issue 1. 1999-06-24. PMID:10193906. |
compared to previous studies using the selective 5-ht1a receptor agonist 8-oh-dpat, the non-selective endogenous serotonin receptor agonist 5-ht was significantly less potent in this paradigm. |
1999-06-24 |
2023-08-12 |
rat |
| M L Wadenberg, K A Young, J T Richter, P B Hick. Effects of local application of 5-hydroxytryptamine into the dorsal or median raphe nuclei on haloperidol-induced catalepsy in the rat. Neuropharmacology. vol 38. issue 1. 1999-06-24. PMID:10193906. |
the early reversal of cat by local 5-ht administration into the mr is in all probability mediated via stimulation of 5-ht1a autoreceptors on raphe serotonergic cell bodies. |
1999-06-24 |
2023-08-12 |
rat |
| M L Wadenberg, K A Young, J T Richter, P B Hick. Effects of local application of 5-hydroxytryptamine into the dorsal or median raphe nuclei on haloperidol-induced catalepsy in the rat. Neuropharmacology. vol 38. issue 1. 1999-06-24. PMID:10193906. |
the reversal of cat following 5-ht injections into the dr might alternatively be mediated via functional mechanisms other than stimulation of 5-ht1a autoreceptors. |
1999-06-24 |
2023-08-12 |
rat |
| E Hajós-Korcsok, R McQuade, T Shar. Influence of 5-HT1A receptors on central noradrenergic activity: microdialysis studies using (+/-)-MDL 73005EF and its enantiomers. Neuropharmacology. vol 38. issue 2. 1999-06-24. PMID:10218872. |
measurements of extracellular 5-ht in hippocampus of anaesthetised rats confirmed that the 5-ht1a receptor agonist action of (+/-)-mdl 73005ef resides in the s(-)- enantiomer. |
1999-06-24 |
2023-08-12 |
rat |
| B Lerer, Y Gelfin, M Gorfine, B Allolio, K P Lesch, M E Newma. 5-HT1A receptor function in normal subjects on clinical doses of fluoxetine: blunted temperature and hormone responses to ipsapirone challenge. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 20. issue 6. 1999-06-24. PMID:10327431. |
serotonergic receptors of the 5-ht1a subtype have been suggested to play a pivotal role in the mechanism of action of antidepressant drugs, including specific serotonin reuptake inhibitors (ssris). |
1999-06-24 |
2023-08-12 |
human |
| F Ferriere, N A Khan, J P Meyniel, P Deschau. Characterisation of serotonin transport mechanisms in rainbow trout peripheral blood lymphocytes: role in PHA-induced lymphoproliferation. Developmental and comparative immunology. vol 23. issue 1. 1999-06-23. PMID:10220067. |
inhibitory effects of increased camp on the proliferation were reversed by the addition of the nanomolar concentrations of 8-oh-dpat, a 5-ht1a receptor agonist which is known to diminish the intracellular camp concentrations, suggesting that serotonin also regulates pha-induced proliferation via 5-ht1a membrane receptors in an autocrine manner. |
1999-06-23 |
2023-08-12 |
Not clear |
| J Wu, G L Kramer, M Kram, M Steciuk, I L Crawford, F Pett. Serotonin and learned helplessness: a regional study of 5-HT1A, 5-HT2A receptors and the serotonin transport site in rat brain. Journal of psychiatric research. vol 33. issue 1. 1999-06-22. PMID:10094235. |
serotonin and learned helplessness: a regional study of 5-ht1a, 5-ht2a receptors and the serotonin transport site in rat brain. |
1999-06-22 |
2023-08-12 |
rat |
| J Wu, G L Kramer, M Kram, M Steciuk, I L Crawford, F Pett. Serotonin and learned helplessness: a regional study of 5-HT1A, 5-HT2A receptors and the serotonin transport site in rat brain. Journal of psychiatric research. vol 33. issue 1. 1999-06-22. PMID:10094235. |
using quantitative autoradiography, we measured the density of 5-ht1a and 5-ht2a receptors and of 5-ht transport sites in medial prefrontal cortex, dorsal hippocampus, septum, hypothalamus, and amygdala in learned helpless rats, and in rats that were nonhelpless after inescapable stress, as well as in shuttlebox-tested and nonhandled controls. |
1999-06-22 |
2023-08-12 |
rat |
| Y Edagawa, H Saito, K Ab. Stimulation of the 5-HT1A receptor selectively suppresses NMDA receptor-mediated synaptic excitation in the rat visual cortex. Brain research. vol 827. issue 1-2. 1999-06-16. PMID:10320714. |
we have previously found that stimulation of serotonin 5-ht1a receptors inhibits the induction of long-term potentiation (ltp) in the rat visual cortex. |
1999-06-16 |
2023-08-12 |
rat |
| J M Storring, A Charest, P Cheng, P R Alber. TATA-driven transcriptional initiation and regulation of the rat serotonin 5-HT1A receptor gene. Journal of neurochemistry. vol 72. issue 6. 1999-06-14. PMID:10349831. |
tata-driven transcriptional initiation and regulation of the rat serotonin 5-ht1a receptor gene. |
1999-06-14 |
2023-08-12 |
rat |
| J M Storring, A Charest, P Cheng, P R Alber. TATA-driven transcriptional initiation and regulation of the rat serotonin 5-HT1A receptor gene. Journal of neurochemistry. vol 72. issue 6. 1999-06-14. PMID:10349831. |
the transcriptional initiation and regulation of the rat serotonin 5-ht1a receptor gene were characterized. |
1999-06-14 |
2023-08-12 |
rat |
| I Artaiz, A Zazpe, J Del Rí. Characterization of serotonergic mechanisms involved in the behavioural inhibition induced by 5-hydroxytryptophan in a modified light-dark test in mice. Behavioural pharmacology. vol 9. issue 2. 1999-06-09. PMID:10065930. |
administration of 5-hydroxytryptophan may consequently represent a valid approach to analyse further the role of 5-ht agents, in particular those acting at 5-ht1a receptors, in animal models of anxiety. |
1999-06-09 |
2023-08-12 |
mouse |
| H Jørgensen, U Knigge, A Kjaer, J Warber. Adrenocorticotropic hormone secretion in rats induced by stimulation with serotonergic compounds. hsj@mfi.ku.dk. Journal of neuroendocrinology. vol 11. issue 4. 1999-06-09. PMID:10223282. |
administration of serotonin (5-ht), 5-hydroxytryptophan (5-htp) in combination with the serotonin reuptake inhibitor fluoxetine (flx), or of the 5-ht agonists 8-oh-dpat (5-ht1a), 5-carboxamido-tryptamine (5-ht1a+1b+5a+7), ru 24969 (5-ht1b+1a), doi (5-ht2a+2c), s-alpha-methyl-5-ht (5-ht2a+2b+2c), mk212 (5-ht2b+2c), or methyl-chlorophenyl-piperazine (5-ht2a+2c) dose-dependently stimulated acth secretion. |
1999-06-09 |
2023-08-12 |
rat |
| H Jørgensen, U Knigge, A Kjaer, J Warber. Adrenocorticotropic hormone secretion in rats induced by stimulation with serotonergic compounds. hsj@mfi.ku.dk. Journal of neuroendocrinology. vol 11. issue 4. 1999-06-09. PMID:10223282. |
it is concluded that 5-ht1a, 5-ht2a+2c, and to a lesser extent 5-ht1b receptors, but not 5-ht3 receptors are involved in the effects of serotonin agonists on acth secretion. |
1999-06-09 |
2023-08-12 |
rat |
| S Williams, M Serafin, M Mühlethaler, L Bernhei. The serotonin inhibition of high-voltage-activated calcium currents is relieved by action potential-like depolarizations in dissociated cholinergic nucleus basalis neurons of the guinea-pig. The European journal of neuroscience. vol 10. issue 10. 1999-06-07. PMID:9786223. |
the aim of the present study was to investigate whether the voltage-dependent inhibition of calcium currents by serotonin 5-ht1a agonists can be alleviated (facilitated) by action potential-like depolarizations. |
1999-06-07 |
2023-08-12 |
Not clear |