All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
M L Rouzade, J Fioramonti, L Buen. Decrease in gastric sensitivity to distension by 5-HT1A receptor agonists in rats. Digestive diseases and sciences. vol 43. issue 9. 1998-10-09. PMID:9753272. using an in vivo model for evaluation of gastric sensitivity in awake rats, we aimed to determine whether 5-hydroxytryptamine 1a (5-ht1a) agonists modify pain threshold and gastric compliance specifically through 5-ht1a receptors. 1998-10-09 2023-08-12 rat
J Dong, C de Montigny, P Blie. Full agonistic properties of BAY x 3702 on presynaptic and postsynaptic 5-HT1A receptors electrophysiological studies in the rat hippocampus and dorsal raphe. The Journal of pharmacology and experimental therapeutics. vol 286. issue 3. 1998-10-08. PMID:9732384. the present studies evaluated the effects of acute and long-term administration of the 5-ht1a agonist bay x 3702 on the responsiveness of dorsal raphe 5-ht neurons and of dorsal hippocampus ca3 pyramidal neurons. 1998-10-08 2023-08-12 rat
J Dong, C de Montigny, P Blie. Full agonistic properties of BAY x 3702 on presynaptic and postsynaptic 5-HT1A receptors electrophysiological studies in the rat hippocampus and dorsal raphe. The Journal of pharmacology and experimental therapeutics. vol 286. issue 3. 1998-10-08. PMID:9732384. bay x 3702 potently reduced the firing activity of 5-ht neurons and of ca3 pyramidal neurons when applied by microiontophoresis and this inhibitory effect of bay x 3702 was fully antagonized by low intravenous doses of the 5-ht1a antagonist way 100635. 1998-10-08 2023-08-12 rat
H J Bengtsson, A Kullberg, M J Millan, S Hjort. The role of 5-HT1A autoreceptors and alpha1-adrenoceptors in the modulation of 5-HT release--III. Clozapine and the novel putative antipsychotic S 16924. Neuropharmacology. vol 37. issue 3. 1998-10-02. PMID:9681933. the role of 5-ht1a autoreceptors and alpha1-adrenoceptors in the modulation of 5-ht release--iii. 1998-10-02 2023-08-12 rat
H J Bengtsson, A Kullberg, M J Millan, S Hjort. The role of 5-HT1A autoreceptors and alpha1-adrenoceptors in the modulation of 5-HT release--III. Clozapine and the novel putative antipsychotic S 16924. Neuropharmacology. vol 37. issue 3. 1998-10-02. PMID:9681933. in the present study, in vivo microdialysis was used to examine the effect of clozapine and s 16924 on 5-ht overflow in the rat ventral hippocampus, and to assess the relative role of putative alpha1-adrenoceptor antagonist and 5-ht1a autoreceptor agonist properties of the drugs in this regard. 1998-10-02 2023-08-12 rat
H J Bengtsson, A Kullberg, M J Millan, S Hjort. The role of 5-HT1A autoreceptors and alpha1-adrenoceptors in the modulation of 5-HT release--III. Clozapine and the novel putative antipsychotic S 16924. Neuropharmacology. vol 37. issue 3. 1998-10-02. PMID:9681933. the 5-ht decrease elicited by s 16924 (1.0 mg/kg, s.c.) was significantly, though only partially, antagonized by pretreatment with the selective 5-ht1a receptor antagonist way 100635 (0.3 mg/kg, s.c.). 1998-10-02 2023-08-12 rat
H J Bengtsson, A Kullberg, M J Millan, S Hjort. The role of 5-HT1A autoreceptors and alpha1-adrenoceptors in the modulation of 5-HT release--III. Clozapine and the novel putative antipsychotic S 16924. Neuropharmacology. vol 37. issue 3. 1998-10-02. PMID:9681933. we conclude that both alpha1-adrenoceptor antagonist and 5-ht1a receptor agonist properties of clozapine and s 16924 contribute to the 5-ht release-reducing action of these drugs. 1998-10-02 2023-08-12 rat
H J Bengtsson, A Kullberg, M J Millan, S Hjort. The role of 5-HT1A autoreceptors and alpha1-adrenoceptors in the modulation of 5-HT release--III. Clozapine and the novel putative antipsychotic S 16924. Neuropharmacology. vol 37. issue 3. 1998-10-02. PMID:9681933. with regard to the interplay between alpha1-adrenoceptor and 5-ht1a (auto)receptor mechanisms in the control of 5-ht release in the rat forebrain, the present data suggest that an excitation mediated by the former is outweighed by the simultaneous activation of the latter-inhibitory-receptors. 1998-10-02 2023-08-12 rat
C M Villalón, D Centurión, G Rabelo, P de Vries, P R Saxena, A Sánchez-Lópe. The 5-HT1-like receptors mediating inhibition of sympathetic vasopressor outflow in the pithed rat: operational correlation with the 5-HT1A, 5-HT1B and 5-HT1D subtypes. British journal of pharmacology. vol 124. issue 5. 1998-10-02. PMID:9692787. continuous infusions of 5-ht and the 5-ht1 receptor agonists, 8-oh-dpat (5-ht1a), indorenate (5-ht1a), cp 93,129 (5-ht1b) and sumatriptan (5-ht(1b/1d)), resulted in a dose-dependent inhibition of sympathetically-induced vasopressor responses. 1998-10-02 2023-08-12 rat
C M Villalón, D Centurión, G Rabelo, P de Vries, P R Saxena, A Sánchez-Lópe. The 5-HT1-like receptors mediating inhibition of sympathetic vasopressor outflow in the pithed rat: operational correlation with the 5-HT1A, 5-HT1B and 5-HT1D subtypes. British journal of pharmacology. vol 124. issue 5. 1998-10-02. PMID:9692787. treatment with blocking doses of the putative 5-ht receptor antagonists, way 100635 (5-ht1a), cyanopindolol (5-ht(1a/1b)) or gr 127935 (5-ht(1b/1d)). 1998-10-02 2023-08-12 rat
P Fischer, J Tauscher, B Küfferle, S Kaspe. Weak antidepressant response after buspirone augmentation of serotonin reuptake inhibitors in refractory severe depression. International clinical psychopharmacology. vol 13. issue 2. 1998-10-01. PMID:9669189. buspirone acts as a partial serotonin agonist at the 5-ht1a receptor. 1998-10-01 2023-08-12 Not clear
D J Bootle, J J Adcock, A G Ramag. The role of central 5-HT receptors in the bronchoconstriction evoked by inhaled capsaicin in anaesthetised guinea-pigs. Neuropharmacology. vol 37. issue 2. 1998-10-01. PMID:9680249. the effects of intracisternal (i.c) injections of the 5-ht1a receptor agonists, buspirone and 8-oh-dpat, and the antagonists way-100635; and (-)-pindolol, the 5-ht1b/1d receptor agonist sumatriptan and antagonist gr127935, the 5-ht2 receptor agonist doi and the antagonist cinanserin, the 5-ht3 receptor antagonist granisetron, the alpha-adrenoceptor agonist clonidine and the antagonist idazoxan, the d2 receptor antagonists (-)-sulpiride and the 5-ht uptake inhibitor fluoxetine on capsaicin-evoked increase in tracheal inflation pressure (bronchoconstriction) were investigated in alpha-chloralose anaesthetised, neuromuscularly blocked, artificially ventilated guinea-pigs. 1998-10-01 2023-08-12 Not clear
F Navas, F L Tang, L T Schaller, M H Norma. Analogues of the potential antipsychotic agent 1192U90: amide modifications. Bioorganic & medicinal chemistry. vol 6. issue 6. 1998-09-29. PMID:9681147. analogues of 2-amino-n-(4-(4-(1,2-benzisothiazol-3-yl)-l-piperazinyl) -butyl)benzamide hydrochloride (1192u90) were prepared and evaluated in receptor binding assays for the dopamine d2, serotonin 5-ht1a, and serotonin 5-ht2 receptors. 1998-09-29 2023-08-12 Not clear
C Stenfors, T Werner, S B Ros. In vivo labelling of the mouse brain 5-hydroxytryptamine1A receptor with the novel selective antagonist 3H-NAD-299. Naunyn-Schmiedeberg's archives of pharmacology. vol 357. issue 5. 1998-09-28. PMID:9650801. the in vivo labelling of 5-hydroxytryptamine (5-ht)1a receptors in the mouse brain was studied with the novel selective 5-ht1a receptor antagonist, nad-299 ((r)-3-n,n-dicyclobutylamino-8-fluoro-3,4-dihydro-2h-1-benzopyran- 5-carboxamide hydrogen (2r,3r)-tartrate monohydrate). 1998-09-28 2023-08-12 mouse
H Schwörer, G Ramador. Autoreceptors can modulate 5-hydroxytryptamine release from porcine and human small intestine in vitro. Naunyn-Schmiedeberg's archives of pharmacology. vol 357. issue 5. 1998-09-28. PMID:9650808. the 5-ht1a receptor agonist (+)-8-hydroxy-dipropylaminotetralin (8-oh-dpat, 1 micromol/l) and the 5-ht2 receptor agonist alpha-methyl-5-ht (1 micromol/l) increased 5-ht release by 40% in about 60% of the human preparations. 1998-09-28 2023-08-12 human
L W Maines, B J Keck, A Dugar, J M Lakosk. Age-dependent loss of corticosterone modulation of central serotonin 5-HT1A receptor binding sites. Journal of neuroscience research. vol 53. issue 1. 1998-09-24. PMID:9670995. age-dependent loss of corticosterone modulation of central serotonin 5-ht1a receptor binding sites. 1998-09-24 2023-08-12 rat
M Zivin, L Sprah, D Ske. Antiparkinsonian potential of interaction of LEK-8829 with bromocriptine. European journal of pharmacology. vol 349. issue 2-3. 1998-09-23. PMID:9671092. the ergoline derivative, lek-8829 (9,10-didehydro-n-methyl-(2-propynyl)-6-methyl-8-aminomethylerg oline), has been proposed as a potential atypical antipsychotic drug with antagonistic actions at dopamine d2 and serotonin 5-ht2 and 5-ht1a receptors (krisch et al., 1994, 1996). 1998-09-23 2023-08-12 rat
D J Mokler, D Lariviere, D W Johnson, N L Theriault, J D Bronzino, M Dixon, P J Morgan. Serotonin neuronal release from dorsal hippocampus following electrical stimulation of the dorsal and median raphé nuclei in conscious rats. Hippocampus. vol 8. issue 3. 1998-09-18. PMID:9662140. this difference in release between non-anesthetized and anesthetized animals may relate to anesthesia blocking long- and/or short-loop serotonin recurrent axonal collaterals negatively feeding back onto 5-ht1a and 5-ht1d somatodendritic autoreceptors on raphé neurons. 1998-09-18 2023-08-12 rat
C Roberts, A Belenguer, D N Middlemiss, C Routledg. Differential effects of 5-HT1B/1D receptor antagonists in dorsal and median raphe innervated brain regions. European journal of pharmacology. vol 346. issue 2-3. 1998-09-16. PMID:9652357. this decrease may be explained by antagonism of inhibitory 5-ht1b/1d receptors on raphe cell bodies, leading to a local increase in 5-ht, which, in turn, stimulated 5-ht1a receptors to decrease cell firing, and hence 5-ht release from terminals. 1998-09-16 2023-08-12 Not clear
N Aguirre, S Ballaz, B Lasheras, J Del Rí. MDMA ('Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion. European journal of pharmacology. vol 346. issue 2-3. 1998-09-16. PMID:9652358. mdma ('ecstasy') enhances 5-ht1a receptor density and 8-oh-dpat-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion. 1998-09-16 2023-08-12 rat