| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pelin Tanyeri, Mehmet Emin Buyukokuroglu, Oguz Mutlu, Güner Ulak, Füruzan Yıldız Akar, Ipek Komsuoglu Celikyurt, Bekir Faruk Erde. Involvement of serotonin receptor subtypes in the antidepressant-like effect of beta receptor agonist Amibegron (SR 58611A): an experimental study. Pharmacology, biochemistry, and behavior. vol 105. 2013-10-23. PMID:23380524. |
to investigate the involvement of serotonin receptors in the effects of amibegron, we used the serotonin 5ht1a receptor antagonist way-100635 (way) or serotonin 5ht2a-2c receptor antagonist ketanserin or serotonin 5ht3 receptor antagonist ondansetron in mice forced swimming test (fst). |
2013-10-23 |
2023-08-12 |
mouse |
| Pelin Tanyeri, Mehmet Emin Buyukokuroglu, Oguz Mutlu, Güner Ulak, Füruzan Yıldız Akar, Ipek Komsuoglu Celikyurt, Bekir Faruk Erde. Involvement of serotonin receptor subtypes in the antidepressant-like effect of beta receptor agonist Amibegron (SR 58611A): an experimental study. Pharmacology, biochemistry, and behavior. vol 105. 2013-10-23. PMID:23380524. |
the antidepressant-like effect of amibegron in the fst seems to be mediated by an interaction with serotonin 5-ht1a, serotonin 5-ht2a-2c and serotonin 5-ht3 receptors. |
2013-10-23 |
2023-08-12 |
mouse |
| A W Moreau, M Amar, J Callebert, P Fossie. Serotonergic modulation of LTP at excitatory and inhibitory synapses in the developing rat visual cortex. Neuroscience. vol 238. 2013-10-17. PMID:23454367. |
when a theta-burst stimulation was applied in layer 2/3 of 5-ht depleted cortical slices (after in vivo treatment with the tryptophan hydroxylase inhibitor p-chlorophenylalanine (pcpa)), or after in vitro perfusion of the potent 5-ht1a receptor antagonist way-100,635, we observed a persistent shift of the ratio between excitation and inhibition toward more inhibition. |
2013-10-17 |
2023-08-12 |
rat |
| A W Moreau, M Amar, J Callebert, P Fossie. Serotonergic modulation of LTP at excitatory and inhibitory synapses in the developing rat visual cortex. Neuroscience. vol 238. 2013-10-17. PMID:23454367. |
in contrast, neither excitatory nor inhibitory postsynaptic currents were potentiated when ltp protocols were delivered in the presence of either the selective serotonin reuptake inhibitor citalopram or the 5-ht1a receptor agonist 8-oh-dpat. |
2013-10-17 |
2023-08-12 |
rat |
| W J Xu, Y Zhao, F Q Huo, J Q Du, J S Tan. Involvement of ventrolateral orbital cortex 5-HT 1-7 receptors in 5-HT induced depression of spared nerve injury allodynia. Neuroscience. vol 238. 2013-10-17. PMID:23485814. |
microinjection of selective 5-ht1a, 5-ht2, 5-ht3, 5-ht4, 5-ht5a, 5-ht6 and 5-ht7 receptor antagonists, 1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl] piperazine hydrobromide (nan-190) (10μg), cyproheptadine (50ng), granisetron hydrochloride (granisetron) (10μg), 1-[2-[(methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl1-methyl-1h-indole-3-carboxylate (gr113808) (5μg), sb699551 dihydrochloride (sb699551) (10μg), sb258585 dihydrochloride (sb258585) (2μg) or sb269970 hydrochloride (sb269970) (10μg) into the vlo 5-min prior to 5-ht (10μg) injection, all antagonized the 5-ht-induced inhibition of allodynia. |
2013-10-17 |
2023-08-12 |
rat |
| Maria Cano-Colino, Rita Almeida, Albert Compt. Serotonergic modulation of spatial working memory: predictions from a computational network model. Frontiers in integrative neuroscience. vol 7. 2013-10-17. PMID:24133418. |
in all our simulations agonists of 5-ht1a receptors and antagonists of 5-ht2a receptors produced behavioral and physiological effects in line with global 5-ht level increases. |
2013-10-17 |
2023-08-12 |
Not clear |
| M Embree, V Michopoulos, J R Votaw, R J Voll, J Mun, J S Stehouwer, M M Goodman, M E Wilson, M M Sánche. The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. Neuroscience. vol 228. 2013-09-23. PMID:23079633. |
the relation of developmental changes in brain serotonin transporter (5htt) and 5ht1a receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5htt genotype. |
2013-09-23 |
2023-08-12 |
human |
| M Embree, V Michopoulos, J R Votaw, R J Voll, J Mun, J S Stehouwer, M M Goodman, M E Wilson, M M Sánche. The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. Neuroscience. vol 228. 2013-09-23. PMID:23079633. |
our findings provide the first longitudinal evidence of developmental increases in 5ht1a receptor and 5htt binding in the brain of female primates from pre- to peripuberty. |
2013-09-23 |
2023-08-12 |
human |
| M Embree, V Michopoulos, J R Votaw, R J Voll, J Mun, J S Stehouwer, M M Goodman, M E Wilson, M M Sánche. The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. Neuroscience. vol 228. 2013-09-23. PMID:23079633. |
the increase in 5ht1a bp(nd) in these socially housed female rhesus monkeys is a robust finding, occurring across all groups, regardless of social status or 5htt genotype, and occurring in the left and right hemispheres of all prefrontal regions studied, as well as the amygdala, hippocampus, hypothalamus, and raphe nuclei. |
2013-09-23 |
2023-08-12 |
human |
| M Embree, V Michopoulos, J R Votaw, R J Voll, J Mun, J S Stehouwer, M M Goodman, M E Wilson, M M Sánche. The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. Neuroscience. vol 228. 2013-09-23. PMID:23079633. |
indeed, the main developmental changes in behavior during the hi (increase in freezing and decrease in submission/appeasement) were related to neurodevelopmental increases in 5ht1a receptors and 5htt, because the associations between these behaviors and 5ht endpoints emerge at peripuberty. |
2013-09-23 |
2023-08-12 |
human |
| M Embree, V Michopoulos, J R Votaw, R J Voll, J Mun, J S Stehouwer, M M Goodman, M E Wilson, M M Sánche. The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. Neuroscience. vol 228. 2013-09-23. PMID:23079633. |
we detected an effect of social status on 5ht1a bp(nd) in the hypothalamus and on 5htt bp(nd) in the orbitofrontal cortex, with subordinates showing higher bp(nd) than dominants in both cases during the pubertal transition. |
2013-09-23 |
2023-08-12 |
human |
| M Embree, V Michopoulos, J R Votaw, R J Voll, J Mun, J S Stehouwer, M M Goodman, M E Wilson, M M Sánche. The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. Neuroscience. vol 228. 2013-09-23. PMID:23079633. |
no main effects of 5htt genotype were observed for 5ht1a or 5htt bp(nd). |
2013-09-23 |
2023-08-12 |
human |
| J L Lukkes, J M Kopelman, N C Donner, M W Hale, C A Lowr. Development × environment interactions control tph2 mRNA expression. Neuroscience. vol 237. 2013-09-23. PMID:23403177. |
no treatment effects were observed on 5-ht1a receptor or serotonin transporter gene expression. |
2013-09-23 |
2023-08-12 |
rat |
| Andrea E Corcoran, George B Richerson, Michael B Harri. Serotonergic mechanisms are necessary for central respiratory chemoresponsiveness in situ. Respiratory physiology & neurobiology. vol 186. issue 2. 2013-09-20. PMID:23454177. |
hypercapnic responses were also assessed during exposure to ketanserin (5-ht2 receptor antagonist), and 8-oh-dpat (inhibiting 5-ht neurons via 5-ht1a autoreceptors). |
2013-09-20 |
2023-08-12 |
rat |
| Takafumi Mizushige, Yurina Sawashi, Ayako Yamada, Ryuhei Kanamoto, Kousaku Ohinat. Characterization of Tyr-Leu-Gly, a novel anxiolytic-like peptide released from bovine αS-casein. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 27. issue 7. 2013-09-18. PMID:23580614. |
the anxiolytic-like activity of ylg was inhibited by way100135, sch23390 or bicuculline, antagonists of serotonin 5-ht1a, dopamine d1, and gaba(a) receptors, respectively; however, ylg had no affinity for these receptors. |
2013-09-18 |
2023-08-12 |
mouse |
| Martin A Santini, Cecilia Ratner, Susana Aznar, Anders B Klein, Gitte M Knudsen, Jens D Mikkelse. Enhanced prefrontal serotonin 2A receptor signaling in the subchronic phencyclidine mouse model of schizophrenia. Journal of neuroscience research. vol 91. issue 5. 2013-09-10. PMID:23404493. |
also, binding of the 5-ht1a r and the 5-ht transporter was unaffected. |
2013-09-10 |
2023-08-12 |
mouse |
| Takafumi Mizushige, Norimasa Kanegawa, Ayako Yamada, Ami Ota, Ryuhei Kanamoto, Kousaku Ohinat. Aromatic amino acid-leucine dipeptides exhibit anxiolytic-like activity in young mice. Neuroscience letters. vol 543. 2013-09-06. PMID:23570730. |
similarly to yl, the anxiolytic-like activities of fl and wl were inhibited by way100135, sch-23390 and bicuculline, antagonists of serotonin 5-ht1a, dopamine d1 and gabaa receptors, respectively, implying that fl and wl activate a common anxiolytic pathway to that of yl. |
2013-09-06 |
2023-08-12 |
mouse |
| Vladimir S Naumenko, Rimma V Kozhemyakina, Irina F Plyusnina, Alexander V Kulikov, Nina K Popov. Serotonin 5-HT1A receptor in infancy-onset aggression: comparison with genetically defined aggression in adult rats. Behavioural brain research. vol 243. 2013-08-28. PMID:23299041. |
serotonin 5-ht1a receptor in infancy-onset aggression: comparison with genetically defined aggression in adult rats. |
2013-08-28 |
2023-08-12 |
rat |
| Nina K Popova, Vladimir S Naumenk. 5-HT1A receptor as a key player in the brain 5-HT system. Reviews in the neurosciences. vol 24. issue 2. 2013-08-21. PMID:23492554. |
among an impressive variety of identified serotonin receptors, 5-ht1a attracts particular attention due to its central role in the regulation of 5-ht-ergic neurotransmission and the data on its involvement in the mechanisms of stress response, aggressive behavior, anxiety, and depression. |
2013-08-21 |
2023-08-12 |
Not clear |
| Nina K Popova, Vladimir S Naumenk. 5-HT1A receptor as a key player in the brain 5-HT system. Reviews in the neurosciences. vol 24. issue 2. 2013-08-21. PMID:23492554. |
this review concentrates on the cross-regulation between 5-ht receptors and the implication of the 5-ht1a receptor in the genetic control of 5-ht-related behavior. |
2013-08-21 |
2023-08-12 |
Not clear |