All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
Bradley T Christian, Dustin W Wooten, Ansel T Hillmer, Dana L Tudorascu, Alexander K Converse, Colleen F Moore, Elizabeth O Ahlers, Todd E Barnhart, Ned H Kalin, Christina S Barr, Mary L Schneide. Serotonin transporter genotype affects serotonin 5-HT1A binding in primates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 6. 2013-04-01. PMID:23392679. serotonin transporter genotype affects serotonin 5-ht1a binding in primates. 2013-04-01 2023-08-12 human
Fredrik Lindstedt, Bianka Karshikoff, Martin Schalling, Caroline Olgart Höglund, Martin Ingvar, Mats Lekander, Eva Kose. Serotonin-1A receptor polymorphism (rs6295) associated with thermal pain perception. PloS one. vol 7. issue 8. 2013-02-19. PMID:22952650. serotonin (5-ht) is highly involved in pain regulation and serotonin-1a (5-ht1a) receptors are important in determining central 5-ht tone. 2013-02-19 2023-08-12 human
Sheila A Arnold, Theo Hag. Serotonin 1A receptor agonist increases species- and region-selective adult CNS proliferation, but not through CNTF. Neuropharmacology. vol 63. issue 7. 2013-02-12. PMID:22884499. here, we investigated the potential role of cntf in the proliferative response to pharmacological stimulation of the serotonin 1a (5-ht1a)(4) receptor, which also inhibits camp, in adult mice and rats. 2013-02-12 2023-08-12 mouse
Osamu Uchiumi, Yoshiyuki Kasahara, Asami Fukui, F Scott Hall, George R Uhl, Ichiro Sor. Serotonergic involvement in the amelioration of behavioral abnormalities in dopamine transporter knockout mice by nicotine. Neuropharmacology. vol 64. 2013-02-11. PMID:22809709. we report nicotine-induced normalization of effects on locomotion and prepulse inhibition of acoustic startle (ppi) in dat ko mice that require intact serotonin 5-ht1a systems. 2013-02-11 2023-08-12 mouse
Taku Yamaguchi, Aki Tsujimatsu, Haruko Kumamoto, Takeshi Izumi, Yu Ohmura, Takayuki Yoshida, Mitsuhiro Yoshiok. Anxiolytic effects of yokukansan, a traditional Japanese medicine, via serotonin 5-HT1A receptors on anxiety-related behaviors in rats experienced aversive stress. Journal of ethnopharmacology. vol 143. issue 2. 2013-01-29. PMID:22819689. anxiolytic effects of yokukansan, a traditional japanese medicine, via serotonin 5-ht1a receptors on anxiety-related behaviors in rats experienced aversive stress. 2013-01-29 2023-08-12 rat
C Mannucci, M Navarra, E Calzavara, A P Caputi, G Calapa. Serotonin involvement in Rhodiola rosea attenuation of nicotine withdrawal signs in rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 19. issue 12. 2013-01-22. PMID:22921986. results show a significant increase of 5-ht content in n treated with r. rosea, with a significant increase of serotonin receptor 1a, suggesting an involvement of serotonin in beneficial effects of r. rosea on suffering produced by nicotine withdrawal. 2013-01-22 2023-08-12 human
Therese M Eriksson, Sarah Holst, Tiberiu L Stan, Torben Hager, Benita Sjögren, Sven Öve Ogren, Per Svenningsson, Oliver Stied. 5-HT1A and 5-HT7 receptor crosstalk in the regulation of emotional memory: implications for effects of selective serotonin reuptake inhibitors. Neuropharmacology. vol 63. issue 6. 2013-01-10. PMID:22801295. 5-ht1a and 5-ht7 receptor crosstalk in the regulation of emotional memory: implications for effects of selective serotonin reuptake inhibitors. 2013-01-10 2023-08-12 mouse
H Y Meltzer, B W Massey, M Horiguch. Serotonin receptors as targets for drugs useful to treat psychosis and cognitive impairment in schizophrenia. Current pharmaceutical biotechnology. vol 13. issue 8. 2012-12-18. PMID:22283753. the 5-ht2a receptor, along with 5-ht1a, 5-ht 2c, 5-ht 6 or 5-ht 7 receptors, all of which are components of the mechanism of action of clozapine, represent important targets for treating multiple aspects of schizophrenia, especially psychosis and cognitive impairment. 2012-12-18 2023-08-12 Not clear
H Y Meltzer, B W Massey, M Horiguch. Serotonin receptors as targets for drugs useful to treat psychosis and cognitive impairment in schizophrenia. Current pharmaceutical biotechnology. vol 13. issue 8. 2012-12-18. PMID:22283753. we review here the extensive preclinical evidence to support the importance of 5-ht2a receptor inverse agonism to the action of clozapine and related atypical apds, and evidence supporting the potential of selective 5-ht2a, 5-ht 6 , and 5-ht 7, antagonists, 5-ht1a partial agonists and 5-ht2c agonists for development of drugs which ameliorate psychosis or cognitive impairment. 2012-12-18 2023-08-12 Not clear
Jorge J Pérez-Maceira, María J Mancebo, Manuel Aldegund. Serotonin-induced brain glycogenolysis in rainbow trout (Oncorhynchus mykiss). The Journal of experimental biology. vol 215. issue Pt 17. 2012-12-12. PMID:22875766. 5-ht1a, 5-ht1b, 5ht2b and 5-ht2c-like receptors appeared to be involved in the glycogenolytic action of 5-ht, although the effect mediated by 5-ht1a or 5-ht1b was apparently stronger. 2012-12-12 2023-08-12 Not clear
Daria Peleg-Raibstein, Edlira Luca, Christian Wolfru. Maternal high-fat diet in mice programs emotional behavior in adulthood. Behavioural brain research. vol 233. issue 2. 2012-12-10. PMID:22633920. in addition, brain-derived neurotrophic factor (bdnf) was significantly increased in the dorsal hippocampus, while gaba(a) alpha2 receptor subunit and 5-hydroxytryptamine 1a (5-ht1a) receptor showed increased levels in the ventral hippocampus. 2012-12-10 2023-08-12 mouse
Nagahisa Okamoto, Kota Sakamoto, Maki Yamad. Transient serotonin syndrome by concurrent use of electroconvulsive therapy and selective serotonin reuptake inhibitor: a case report and review of the literature. Case reports in psychiatry. vol 2012. 2012-12-06. PMID:23213590. the serotonin syndrome, which is characterized by psychiatric, autonomic nervous and neurological symptoms, is considered to be caused by excessive stimulation of the 5-ht1a and 5-ht2 receptors in the gray matter and spinal cord of the central nervous system, after the start of dosing or increase of the dose of a serotoninergic drug. 2012-12-06 2023-08-12 Not clear
Ute Renner, Andre Zeug, Andrew Woehler, Marcus Niebert, Alexander Dityatev, Galina Dityateva, Nataliya Gorinski, Daria Guseva, Dalia Abdel-Galil, Matthias Fröhlich, Frank Döring, Erhard Wischmeyer, Diethelm W Richter, Erwin Neher, Evgeni G Ponimaski. Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking. Journal of cell science. vol 125. issue Pt 10. 2012-12-03. PMID:22357950. heterodimerization of serotonin receptors 5-ht1a and 5-ht7 differentially regulates receptor signalling and trafficking. 2012-12-03 2023-08-12 Not clear
Beow Keat Yap, Michael J C Buckle, Stephen W Dought. Homology modeling of the human 5-HT1A, 5-HT 2A, D1, and D2 receptors: model refinement with molecular dynamics simulations and docking evaluation. Journal of molecular modeling. vol 18. issue 8. 2012-11-30. PMID:22354276. homology modeling of the human 5-ht1a, 5-ht 2a, d1, and d2 receptors: model refinement with molecular dynamics simulations and docking evaluation. 2012-11-30 2023-08-12 human
Eiji Kirin. Efficacy and safety of aripiprazole in child and adolescent patients. European child & adolescent psychiatry. vol 21. issue 7. 2012-11-26. PMID:22447196. aripiprazole (apz) has a unique pharmacological profile, as a partial agonist at the dopamine d2 and serotonin 5ht1a receptors and an antagonist at the serotonin 5ht2a receptor; this drug has few side effects (such as extrapyramidal syndrome, hyperprolactinemia, weight gain, metabolic disorders, and sedation) which are typical problems with other antipsychotic drugs. 2012-11-26 2023-08-12 Not clear
Masatoshi Inden, Mari Abe, Hideaki Minamino, Kazuyuki Takata, Kanji Yoshimoto, Ikuo Tooyama, Yoshihisa Kitamur. Effect of selective serotonin reuptake inhibitors via 5-HT1A receptors on L-DOPA-induced rotational behavior in a hemiparkinsonian rat model. Journal of pharmacological sciences. vol 119. issue 1. 2012-11-20. PMID:22510520. effect of selective serotonin reuptake inhibitors via 5-ht1a receptors on l-dopa-induced rotational behavior in a hemiparkinsonian rat model. 2012-11-20 2023-08-12 rat
M L Berger, R Palangsuntikul, P Rebernik, P Wolschann, H Berne. Screening of 64 tryptamines at NMDA, 5-HT1A, and 5-HT2A receptors: a comparative binding and modeling study. Current medicinal chemistry. vol 19. issue 18. 2012-10-18. PMID:22519402. the most potent inhibitors at 5-ht1a receptors were 5-carboxamido-t (ic50 0.00015 μm) and serotonin (0.0016 μm), at 5-ht2a receptors 2-me-4,7-cl2-t (1.2 μm) and 2,7-me2-4-cl-t (2.0 μm). 2012-10-18 2023-08-12 rat
Hideho Arit. [The neuroscience of suicide]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 8. 2012-10-18. PMID:22868884. suicide victims have fewer 5-ht transporter sites and a large number of postsynaptic 5-ht1a and 5-ht receptors in the vlpfc, which are implicated in behavioral inhibition and impulsivity. 2012-10-18 2023-08-12 Not clear
Hideho Arit. [The neuroscience of suicide]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 8. 2012-10-18. PMID:22868884. in the drn of suicide cases, 5-ht1a autoreceptors are increased and the levels of 5-ht biosynthetic enzyme, tryptophan hydroxylase (tph), are reduced. 2012-10-18 2023-08-12 Not clear
Hideho Arit. [The neuroscience of suicide]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 8. 2012-10-18. PMID:22868884. reduced 5-ht1a feedback inhibition and increased tph may reflect compensatory changes in response to 5-ht hypofunction in depression-related suicide. 2012-10-18 2023-08-12 Not clear