| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mei Huang, Masakuni Horiguchi, Anna R Felix, Herbert Y Meltze. 5-HT1A and 5-HT7 receptors contribute to lurasidone-induced dopamine efflux. Neuroreport. vol 23. issue 7. 2012-08-02. PMID:22415605. |
lurasidone is a novel, atypical antipsychotic drug with serotonin [5-hydroxytryptamine (5-ht)]2a, 5-ht7, dopamine (da) d2 antagonist, and 5-ht1a receptor partial agonist properties. |
2012-08-02 |
2023-08-12 |
rat |
| Shunsuke Tanahashi, Satoshi Yamamura, Masanori Nakagawa, Eishi Motomura, Motohiro Okad. Dopamine D2 and serotonin 5-HT1A receptors mediate the actions of aripiprazole in mesocortical and mesoaccumbens transmission. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:21925189. |
dopamine d2 and serotonin 5-ht1a receptors mediate the actions of aripiprazole in mesocortical and mesoaccumbens transmission. |
2012-07-27 |
2023-08-12 |
Not clear |
| Shunsuke Tanahashi, Satoshi Yamamura, Masanori Nakagawa, Eishi Motomura, Motohiro Okad. Dopamine D2 and serotonin 5-HT1A receptors mediate the actions of aripiprazole in mesocortical and mesoaccumbens transmission. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:21925189. |
the antipsychotic agent aripiprazole acts as a partial agonist of dopamine d2 and serotonin 5-ht1a receptors. |
2012-07-27 |
2023-08-12 |
Not clear |
| Katsuyoshi Mizukami, Masanori Ishikawa, Hiroyasu Akatsu, Eric E Abrahamson, Milos D Ikonomovic, Takashi Asad. An immunohistochemical study of the serotonin 1A receptor in the hippocampus of subjects with Alzheimer's disease. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 31. issue 5. 2012-07-23. PMID:21269332. |
alterations in the serotonin 1a (5-ht1a) receptor can contribute to impaired cognitive function in ad, and both in vitro binding and positron emission tomography (pet) imaging studies have demonstrated that 5-ht1a receptors in the hippocampus/medial temporal cortex are affected early in ad. |
2012-07-23 |
2023-08-12 |
human |
| Isabella Peruga, Silvia Hartwig, Doron Merkler, Jan Thöne, Bernhard Hovemann, Georg Juckel, Ralf Gold, Ralf A Linke. Endogenous ciliary neurotrophic factor modulates anxiety and depressive-like behavior. Behavioural brain research. vol 229. issue 2. 2012-07-17. PMID:22266927. |
in the hippocampus of 20 weeks old, but not 10 weeks old, cntf -/- mice, these changes correlated with a loss of parvalbumin immunoreactive gabaergic interneurons and a reduction of serotonin levels as well as 5-ht receptor 1a expression. |
2012-07-17 |
2023-08-12 |
mouse |
| Dasiel O Borroto-Escuela, Wilber Romero-Fernandez, Mileidys Pérez-Alea, Manuel Narvaez, Alexander O Tarakanov, Giuseppa Mudó, Luigi F Agnati, Francisco Ciruela, Natale Belluardo, Kjell Fux. The existence of FGFR1-5-HT1A receptor heterocomplexes in midbrain 5-HT neurons of the rat: relevance for neuroplasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 18. 2012-06-25. PMID:22553035. |
the combined treatment with fgf-2 and the 5-ht1a agonist also synergistically increased fgfr1 and erk1/2 phosphorylation in the raphe midline area of the midbrain and the rn33b cells as well as their differentiation, as seen from development of the increased number and length of extensions per cell and their increased 5-ht immunoreactivity. |
2012-06-25 |
2023-08-12 |
rat |
| Dasiel O Borroto-Escuela, Wilber Romero-Fernandez, Mileidys Pérez-Alea, Manuel Narvaez, Alexander O Tarakanov, Giuseppa Mudó, Luigi F Agnati, Francisco Ciruela, Natale Belluardo, Kjell Fux. The existence of FGFR1-5-HT1A receptor heterocomplexes in midbrain 5-HT neurons of the rat: relevance for neuroplasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 18. 2012-06-25. PMID:22553035. |
together, the results indicate that the 5-ht1a autoreceptors by being part of a fgfr1-5-ht1a receptor heterocomplex in the midbrain raphe 5-ht nerve cells appear to have a trophic role in the central 5-ht neuron systems in addition to playing a key role in reducing the firing of these neurons. |
2012-06-25 |
2023-08-12 |
rat |
| Patrick Jern, Lars Westberg, Ada Johansson, Annika Gunst, Elias Eriksson, Kenneth Sandnabba, Pekka Santtil. A study of possible associations between single nucleotide polymorphisms in the serotonin receptor 1A, 1B, and 2C genes and self-reported ejaculation latency time. The journal of sexual medicine. vol 9. issue 3. 2012-06-18. PMID:22240001. |
attempts to investigate effects of polymorphisms in serotonergic genes have been carried out, but so far, no study has conducted exploratory genotype analyses regarding the serotonin receptor 1a, 1b, and 2c subtypes, which have been hypothesized to mediate the inhibitory effects of serotonin on ejaculation in rodents. |
2012-06-18 |
2023-08-12 |
Not clear |
| Yuejun Huang, Hongwu Xu, Hui Li, Hanhua Yang, Yunbin Chen, Xuechuan Sh. Pre-gestational stress reduces the ratio of 5-HIAA to 5-HT and the expression of 5-HT1A receptor and serotonin transporter in the brain of foetal rat. BMC neuroscience. vol 13. 2012-06-08. PMID:22373128. |
pre-gestational stress reduces the ratio of 5-hiaa to 5-ht and the expression of 5-ht1a receptor and serotonin transporter in the brain of foetal rat. |
2012-06-08 |
2023-08-12 |
rat |
| M Victoria Puig, Allan T Gulledg. Serotonin and prefrontal cortex function: neurons, networks, and circuits. Molecular neurobiology. vol 44. issue 3. 2012-06-05. PMID:22076606. |
the most abundant serotonin receptors in the pfc, 5-ht1a, 5-ht2a and 5-ht3a receptors, are selectively expressed in distinct populations of pyramidal neurons and inhibitory interneurons, and play a critical role in modulating cortical activity and neural oscillations (brain waves). |
2012-06-05 |
2023-08-12 |
rat |
| Zhong-Lun Chen, Gan-Quan Liu, Xiao-Jun Li, Pei-Xi Che. [Inhibition of 8-OH-DPAT on spontaneous unit discharges of 5-hydroxytryptamine inhibitory unit in rat primary somatosensory cortex]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 22. issue 1. 2012-05-31. PMID:21186594. |
to investigate the effect of 5-hydroxytryptamine (5-ht) on spontaneous unit discharges of primary somatosensory cortex (si-sud) and the role of 5-ht1a receptor in 5-ht inhibitory effect on si-sud in rat. |
2012-05-31 |
2023-08-12 |
rat |
| Cécile Bétry, Adeline Etiévant, Laura Lambás-Señas, Andrew C McCreary, Nasser Haddjer. In vivo effects of pardoprunox (SLV308), a partial D₂/D₃ receptor and 5-HT1A receptor agonist, on rat dopamine and serotonin neuronal activity. Synapse (New York, N.Y.). vol 65. issue 10. 2012-05-30. PMID:21446003. |
in vivo effects of pardoprunox (slv308), a partial d₂/d₃ receptor and 5-ht1a receptor agonist, on rat dopamine and serotonin neuronal activity. |
2012-05-30 |
2023-08-12 |
rat |
| Corinne Y Ostock, Kristin B Dupre, Karen L Eskow Jaunarajs, Hannah Walters, Jessica George, David Krolewski, Paul D Walker, Christopher Bisho. Role of the primary motor cortex in L-Dopa-induced dyskinesia and its modulation by 5-HT1A receptor stimulation. Neuropharmacology. vol 61. issue 4. 2012-05-25. PMID:21635907. |
while serotonin 5-ht1a receptor (5-ht1ar) agonists reduce l-dopa-induced dyskinesias (lid) by normalizing activity in the basal ganglia neurocircuitry, recent evidence suggests putative 5-ht1ar within the primary motor cortex (m1) may also contribute. |
2012-05-25 |
2023-08-12 |
rat |
| Rudi Henriksen, Nishtman Dizeyi, Per-Anders Abrahamsso. Expression of serotonin receptors 5-HT1A, 5-HT1B, 5-HT2B and 5-HT4 in ovary and in ovarian tumours. Anticancer research. vol 32. issue 4. 2012-05-24. PMID:22493371. |
expression of serotonin receptors 5-ht1a, 5-ht1b, 5-ht2b and 5-ht4 in ovary and in ovarian tumours. |
2012-05-24 |
2023-08-12 |
Not clear |
| Hernán Pessoa-Mahana, Gonzalo Recabarren-Gajardo, Jenny Fiedler Temer, Gerald Zapata-Torres, C David Pessoa-Mahana, Claudio Saitz Barría, Ramiro Araya-Maturan. Synthesis, docking studies and biological evaluation of benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one derivatives on 5-HT1A serotonin receptors. Molecules (Basel, Switzerland). vol 17. issue 2. 2012-05-18. PMID:22306829. |
synthesis, docking studies and biological evaluation of benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one derivatives on 5-ht1a serotonin receptors. |
2012-05-18 |
2023-08-12 |
Not clear |
| R L Dennis, H W Chen. Effects of selective serotonin antagonism on central neurotransmission. Poultry science. vol 91. issue 4. 2012-05-10. PMID:22399719. |
analysis of serotonin (5-ht) mediation of aggression in subordinate hens of these strains revealed increases in aggression in dxl hens following antagonism of the 5-ht1a receptor and in hgps hens following antagonism of the 5-ht1b receptor. |
2012-05-10 |
2023-08-12 |
Not clear |
| R L Dennis, H W Chen. Effects of selective serotonin antagonism on central neurotransmission. Poultry science. vol 91. issue 4. 2012-05-10. PMID:22399719. |
increased aggressiveness in dxl hens did not coincide with a reduction in raphe nucleus 5-ht or turnover (as indicated by 5-hydroxyindoleacetic acid levels) following 5-ht1a antagonism. |
2012-05-10 |
2023-08-12 |
Not clear |
| R L Dennis, H W Chen. Effects of selective serotonin antagonism on central neurotransmission. Poultry science. vol 91. issue 4. 2012-05-10. PMID:22399719. |
a reduction in 5-hydroxyindoleacetic acid (but not 5-ht) was seen in hgps hens treated with 5-ht1a antagonist; however, these hens exhibited no change in aggressive behaviors. |
2012-05-10 |
2023-08-12 |
Not clear |
| Melinda Bence, Julia Koller, Maria Sasvari-Szekely, Gergely Keszle. Transcriptional modulation of monoaminergic neurotransmission genes by the histone deacetylase inhibitor trichostatin A in neuroblastoma cells. Journal of neural transmission (Vienna, Austria : 1996). vol 119. issue 1. 2012-05-07. PMID:21785940. |
to this end, short-term parallel cultures of sk-nf-i neuroblastoma cells were treated with tsa either alone or in combination with hypoxia, and mrna levels of dopamine receptor d3 (drd3) and d4 (drd4), dopamine transporter (dat), dopamine hydroxylase (dbh), dopamine receptor regulating factor (drrf), catechol-o-methyltransferase (comt), serotonin receptor 1a (htr1a), monoamino oxidase a (mao-a), serotonin transporter (slc6a4) and tryptophan hydroxylase 2 (tph2) were determined by quantitative pcr. |
2012-05-07 |
2023-08-12 |
human |
| Margaret Czesak, Brice Le François, Anne M Millar, Mariam Deria, Mireille Daigle, Jane E Visvader, Hymie Anisman, Paul R Alber. Increased serotonin-1A (5-HT1A) autoreceptor expression and reduced raphe serotonin levels in deformed epidermal autoregulatory factor-1 (Deaf-1) gene knock-out mice. The Journal of biological chemistry. vol 287. issue 9. 2012-04-25. PMID:22232550. |
increased serotonin-1a (5-ht1a) autoreceptor expression and reduced raphe serotonin levels in deformed epidermal autoregulatory factor-1 (deaf-1) gene knock-out mice. |
2012-04-25 |
2023-08-12 |
mouse |