| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chihiro Suzuki, Chihiro Miyamoto, Tomoyuki Furuyashiki, Shuh Narumiya, Kousaku Ohinat. Central PGE2 exhibits anxiolytic-like activity via EP1 and EP4 receptors in a manner dependent on serotonin 5-HT1A, dopamine D1 and GABAA receptors. FEBS letters. vol 585. issue 14. 2011-10-03. PMID:21693121. |
central pge2 exhibits anxiolytic-like activity via ep1 and ep4 receptors in a manner dependent on serotonin 5-ht1a, dopamine d1 and gabaa receptors. |
2011-10-03 |
2023-08-12 |
mouse |
| Robin Sperling, Kathryn G Common. Shifting topographic activation and 5-HT1A receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. The European journal of neuroscience. vol 33. issue 10. 2011-09-26. PMID:21501256. |
shifting topographic activation and 5-ht1a receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. |
2011-09-26 |
2023-08-12 |
Not clear |
| Robin Sperling, Kathryn G Common. Shifting topographic activation and 5-HT1A receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. The European journal of neuroscience. vol 33. issue 10. 2011-09-26. PMID:21501256. |
to understand the role of 5-ht1a receptor feedback inhibitory pathways in 5-ht cell activity during these conditions, we administered a selective 5-ht1a receptor antagonist and measured novel disinhibited fos expression within 5-ht cells. |
2011-09-26 |
2023-08-12 |
Not clear |
| Robin Sperling, Kathryn G Common. Shifting topographic activation and 5-HT1A receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. The European journal of neuroscience. vol 33. issue 10. 2011-09-26. PMID:21501256. |
using these approaches, we found evidence that acute nicotine exposure activates 5-ht neurons rostrally and in the lateral wings of the dr, whereas there is 5-ht1a receptor-dependent inhibition of cells located ventrally at both the rostral level and mid-level. |
2011-09-26 |
2023-08-12 |
Not clear |
| Robin Sperling, Kathryn G Common. Shifting topographic activation and 5-HT1A receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. The European journal of neuroscience. vol 33. issue 10. 2011-09-26. PMID:21501256. |
previous chronic nicotine exposure did not modify the pattern of activation produced by acute nicotine exposure, but increased 5-ht1a receptor-dependent inhibition of 5-ht cells in the caudal dr. |
2011-09-26 |
2023-08-12 |
Not clear |
| Robin Sperling, Kathryn G Common. Shifting topographic activation and 5-HT1A receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. The European journal of neuroscience. vol 33. issue 10. 2011-09-26. PMID:21501256. |
these results suggest that the distinct behavioral states produced by nicotine exposure and withdrawal correlate with reciprocal rostral-caudal patterns of activation and 5-ht1a receptor-mediated inhibition of dr 5-ht neurons. |
2011-09-26 |
2023-08-12 |
Not clear |
| Hai Zhang, Na Ye, Shanglin Zhou, Lin Guo, Longtai Zheng, Zhili Liu, Bo Gao, Xuechu Zhen, Ao Zhan. Identification of N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate as a new anti-Parkinson's agent possessing a dopamine D2 and serotonin 5-HT1A dual-agonist profile. Journal of medicinal chemistry. vol 54. issue 13. 2011-09-23. PMID:21591752. |
identification of n-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate as a new anti-parkinson's agent possessing a dopamine d2 and serotonin 5-ht1a dual-agonist profile. |
2011-09-23 |
2023-08-12 |
rat |
| J Xu, Gl Zhang, Yq Cheng, B Chen, Y Dong, Lq Li, L Xu, Xf Xu, Zp Lu, Jf We. Hypomethylation of the HTR1A promoter region and high expression of HTR1A in the peripheral blood lymphocytes of patients with systemic lupus erythematosus. Lupus. vol 20. issue 7. 2011-09-14. PMID:21382916. |
some neurotransmitters, such as serotonin, can regulate t- and b-cell proliferation via the 5-ht1a receptor and are involved in the pathology of sle. |
2011-09-14 |
2023-08-12 |
Not clear |
| Jasmin M Dao, Susan C McQuown, Sandra E Loughlin, James D Belluzzi, Frances M Lesli. Nicotine alters limbic function in adolescent rat by a 5-HT1A receptor mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 7. 2011-08-10. PMID:21412223. |
nicotine enhancement of cocaine self-administration and quinpirole-induced locomotor activity was blocked by co-administration of way 100 635 (n-{2-[4-(2-methoxyphenyl)-1-piperazinyl] ethyl}-n-(2-pyridinyl)cyclohexanecarboxamide), a selective serotonin 1a (5-ht1a) receptor antagonist. |
2011-08-10 |
2023-08-12 |
rat |
| David F Cummings, Diana C Canseco, Pratikkumar Sheth, James E Johnson, John A Schet. Synthesis and structure-affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5-HT1A, 5-HT2A, 5-HT2C receptor subtypes. Bioorganic & medicinal chemistry. vol 18. issue 13. 2011-07-21. PMID:20570529. |
synthesis and structure-affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5-ht1a, 5-ht2a, 5-ht2c receptor subtypes. |
2011-07-21 |
2023-08-12 |
human |
| David F Cummings, Diana C Canseco, Pratikkumar Sheth, James E Johnson, John A Schet. Synthesis and structure-affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5-HT1A, 5-HT2A, 5-HT2C receptor subtypes. Bioorganic & medicinal chemistry. vol 18. issue 13. 2011-07-21. PMID:20570529. |
twenty aplysinopsin derivatives were synthesized, purified and tested for their affinities for cloned human serotonin 5-ht1a, 5-ht2a, and 5-ht2c receptor subtypes. |
2011-07-21 |
2023-08-12 |
human |
| David F Cummings, Diana C Canseco, Pratikkumar Sheth, James E Johnson, John A Schet. Synthesis and structure-affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5-HT1A, 5-HT2A, 5-HT2C receptor subtypes. Bioorganic & medicinal chemistry. vol 18. issue 13. 2011-07-21. PMID:20570529. |
the compound (e)-5-((5,6-dichloro-1h-indol-3-yl)methylene)-2-imino-1,3-dimethylimidazolidin-4-one (unt-twu-22, 16) had approximately 2100-fold selectivity for the serotonin 5-ht2c receptor subtype: an affinity for 5-ht2c equal to 46 nm and no detectable affinity for the 5-ht1a or 5-ht2a receptor subtypes. |
2011-07-21 |
2023-08-12 |
human |
| Tomoko Horisawa, Tadashi Ishibashi, Hiroyuki Nishikawa, Takeshi Enomoto, Satoko Toma, Takeo Ishiyama, Mutsuo Taij. The effects of selective antagonists of serotonin 5-HT7 and 5-HT1A receptors on MK-801-induced impairment of learning and memory in the passive avoidance and Morris water maze tests in rats: mechanistic implications for the beneficial effects of the novel atypical antipsychotic lurasidone. Behavioural brain research. vol 220. issue 1. 2011-07-15. PMID:21277905. |
the effects of selective antagonists of serotonin 5-ht7 and 5-ht1a receptors on mk-801-induced impairment of learning and memory in the passive avoidance and morris water maze tests in rats: mechanistic implications for the beneficial effects of the novel atypical antipsychotic lurasidone. |
2011-07-15 |
2023-08-12 |
rat |
| Friederike Klempin, Harish Babu, Davide De Pietri Tonelli, Edson Alarcon, Klaus Fabel, Gerd Kemperman. Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis. Frontiers in molecular neuroscience. vol 3. 2011-07-14. PMID:20721314. |
oppositional effects of serotonin receptors 5-ht1a, 2, and 2c in the regulation of adult hippocampal neurogenesis. |
2011-07-14 |
2023-08-12 |
Not clear |
| Concetta Crisafulli, Chiara Fabbri, Stefano Porcelli, Antonio Drago, Edoardo Spina, Diana De Ronchi, Alessandro Serrett. Pharmacogenetics of antidepressants. Frontiers in pharmacology. vol 2. 2011-07-14. PMID:21687501. |
they include the cytochrome p450 superfamily, the p-glycoprotein (abcb1), the tryptophan hydroxylase, the catechol-o-methyltransferase, the monoamine oxidase a, the serotonin transporter (5-httlpr), the norepinephrine transporter, the dopamine transporter, variants in the 5-hydroxytryptamine receptors (5-ht1a, 5-ht2a, 5-ht3a, 5-ht3b, and 5-ht6), adrenoreceptor beta-1 and alpha-2, the dopamine receptors (d2), the g protein beta 3 subunit, the corticotropin releasing hormone receptors (crhr1 and crhr2), the glucocorticoid receptors, the c-amp response-element binding, and the brain-derived neurotrophic factor. |
2011-07-14 |
2023-08-12 |
human |
| Eelke Snoeren, Johnny Chan, Astrid Bovens, Edwin Cuppen, Marcel Waldinger, Berend Olivier, Ronald Oostin. Serotonin transporter null mutation and sexual behavior in female rats: 5-HT1A receptor desensitization. The journal of sexual medicine. vol 7. issue 7. 2011-06-22. PMID:20456632. |
serotonin transporter null mutation and sexual behavior in female rats: 5-ht1a receptor desensitization. |
2011-06-22 |
2023-08-12 |
human |
| Mahmoud R Hadjighassem, Kimberly Galaraga, Paul R Alber. Freud-2/CC2D1B mediates dual repression of the serotonin-1A receptor gene. The European journal of neuroscience. vol 33. issue 2. 2011-06-01. PMID:21155902. |
the serotonin-1a (5-ht1a) receptor functions as a pre-synaptic autoreceptor in serotonin neurons that regulates their activity, and is also widely expressed on non-serotonergic neurons as a post-synaptic heteroreceptor to mediate serotonin action. |
2011-06-01 |
2023-08-12 |
mouse |
| D V Bazovkina, E E Terenina, A V Kuliko. Effect of selective agonist of serotonin 5-HT1A receptors on defensive behavior in mice with different predisposition to catalepsy. Bulletin of experimental biology and medicine. vol 150. issue 2. 2011-05-20. PMID:21240379. |
effect of selective agonist of serotonin 5-ht1a receptors on defensive behavior in mice with different predisposition to catalepsy. |
2011-05-20 |
2023-08-12 |
mouse |
| D V Bazovkina, E E Terenina, A V Kuliko. Effect of selective agonist of serotonin 5-HT1A receptors on defensive behavior in mice with different predisposition to catalepsy. Bulletin of experimental biology and medicine. vol 150. issue 2. 2011-05-20. PMID:21240379. |
we studied the effect of activation of serotonin 5-ht1a receptors with selective agonist 8-oh-dpat (0.1, 0.5, and 1.0 mg/kg) on intraspecies aggression and freezing reaction (catalepsy) in male mice of catalepsy-resistant akr/j and two catalepsy-prone strains cba/lac and congenic akr.cba-d13mit76. |
2011-05-20 |
2023-08-12 |
mouse |
| Satoshi Yamamura, Masao Abe, Masanori Nakagawa, Shinichiro Ochi, Shu-ichi Ueno, Motohiro Okad. Different actions for acute and chronic administration of mirtazapine on serotonergic transmission associated with raphe nuclei and their innervation cortical regions. Neuropharmacology. vol 60. issue 4. 2011-05-12. PMID:21195096. |
blockade of 5-ht1a receptor, but not that of the 5-ht2a/2c receptor, enhanced the effects of acute administration of mirtazapine on extracellular serotonin level in raphe nuclei. |
2011-05-12 |
2023-08-12 |
Not clear |