| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Susanne Nikolaus, Christina Antke, Markus Beu, Hans-Wilhelm Mülle. Cortical GABA, striatal dopamine and midbrain serotonin as the key players in compulsive and anxiety disorders--results from in vivo imaging studies. Reviews in the neurosciences. vol 21. issue 2. 2010-07-29. PMID:20614802. |
as gaba and 5-ht inhibit daergic neurotransmission, the reductions of gabaa, 5-ht1a and sert can be assumed to result in an enhanced activity of the mesolimbic daergic system. |
2010-07-29 |
2023-08-12 |
Not clear |
| Olga O Yevtushenko, Mykhaylo M Oros, Gavin P Reynold. Early response to selective serotonin reuptake inhibitors in panic disorder is associated with a functional 5-HT1A receptor gene polymorphism. Journal of affective disorders. vol 123. issue 1-3. 2010-07-26. PMID:19800133. |
early response to selective serotonin reuptake inhibitors in panic disorder is associated with a functional 5-ht1a receptor gene polymorphism. |
2010-07-26 |
2023-08-12 |
human |
| Patrizia Bianchi, Elisabetta Ciani, Sandra Guidi, Stefania Trazzi, Daniela Felice, Gabriele Grossi, Mercedes Fernandez, Alessandro Giuliani, Laura Calzà, Renata Bartesagh. Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592198. |
in the hippocampus of untreated p15 ts65dn mice, we found normal 5-ht levels but a lower expression of 5-ht1a receptors and brain-derived neurotrophic factor (bdnf). |
2010-07-22 |
2023-08-12 |
mouse |
| Tadashi Ishibashi, Tomoko Horisawa, Kumiko Tokuda, Takeo Ishiyama, Masaaki Ogasa, Rie Tagashira, Kenji Matsumoto, Hiroyuki Nishikawa, Yoko Ueda, Satoko Toma, Hitomi Oki, Norihiko Tanno, Ikutaro Saji, Akira Ito, Yukihiro Ohno, Mitsutaka Nakamur. Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity. The Journal of pharmacology and experimental therapeutics. vol 334. issue 1. 2010-07-13. PMID:20404009. |
pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-ht7) and 5-ht1a receptor activity. |
2010-07-13 |
2023-08-12 |
human |
| Meredith A Fox, Alison R Stein, Helen T French, Dennis L Murph. Functional interactions between 5-HT2A and presynaptic 5-HT1A receptor-based responses in mice genetically deficient in the serotonin 5-HT transporter (SERT). British journal of pharmacology. vol 159. issue 4. 2010-07-09. PMID:20128812. |
functional interactions between 5-ht2a and presynaptic 5-ht1a receptor-based responses in mice genetically deficient in the serotonin 5-ht transporter (sert). |
2010-07-09 |
2023-08-12 |
mouse |
| Markus Thamm, Sabine Balfanz, Ricarda Scheiner, Arnd Baumann, Wolfgang Blena. Characterization of the 5-HT1A receptor of the honeybee (Apis mellifera) and involvement of serotonin in phototactic behavior. Cellular and molecular life sciences : CMLS. vol 67. issue 14. 2010-07-06. PMID:20349263. |
characterization of the 5-ht1a receptor of the honeybee (apis mellifera) and involvement of serotonin in phototactic behavior. |
2010-07-06 |
2023-08-12 |
Not clear |
| Eric Marvin, Karie Scrogin, Bertalan Dudá. Morphology and distribution of neurons expressing serotonin 5-HT1A receptors in the rat hypothalamus and the surrounding diencephalic and telencephalic areas. Journal of chemical neuroanatomy. vol 39. issue 4. 2010-06-29. PMID:20080175. |
morphology and distribution of neurons expressing serotonin 5-ht1a receptors in the rat hypothalamus and the surrounding diencephalic and telencephalic areas. |
2010-06-29 |
2023-08-12 |
rat |
| H Karlsson, J Hirvonen, J Kajander, J Markkula, H Rasi-Hakala, J K Salminen, K Någren, S Aalto, J Hietal. Research letter: Psychotherapy increases brain serotonin 5-HT1A receptors in patients with major depressive disorder. Psychological medicine. vol 40. issue 3. 2010-06-25. PMID:19903365. |
research letter: psychotherapy increases brain serotonin 5-ht1a receptors in patients with major depressive disorder. |
2010-06-25 |
2023-08-12 |
Not clear |
| Wayne E Childers, Lisa M Havran, Magda Asselin, James J Bicksler, Dan C Chong, George T Grosu, Zhongqi Shen, Magid A Abou-Gharbia, Alvin C Bach, Boyd L Harrison, Natasha Kagan, Teresa Kleintop, Ronald Magolda, Vasilios Marathias, Albert J Robichaud, Annmarie L Sabb, Mei-Yi Zhang, Terrance H Andree, Susan H Aschmies, Chad Beyer, Thomas A Comery, Mark Day, Steven M Grauer, Zoe A Hughes, Sharon Rosenzweig-Lipson, Brian Platt, Claudine Pulicicchio, Deborah E Smith, Stacy J Sukoff-Rizzo, Kelly M Sullivan, Adedayo Adedoyin, Christine Huselton, Warren D Hirs. The synthesis and biological evaluation of quinolyl-piperazinyl piperidines as potent serotonin 5-HT1A antagonists. Journal of medicinal chemistry. vol 53. issue 10. 2010-06-22. PMID:20443629. |
the synthesis and biological evaluation of quinolyl-piperazinyl piperidines as potent serotonin 5-ht1a antagonists. |
2010-06-22 |
2023-08-12 |
Not clear |
| Christian Beste, Katharina Domschke, Vasil Kolev, Juliana Yordanova, Anna Baffa, Michael Falkenstein, Carsten Konra. Functional 5-HT1a receptor polymorphism selectively modulates error-specific subprocesses of performance monitoring. Human brain mapping. vol 31. issue 4. 2010-06-21. PMID:19780043. |
in summary, the results suggest a specific effect of the 5-ht1a c(-1019)g polymorphism on error monitoring, as reflected in the ne, and suggest a neurobiological dissociation between processes of error monitoring and general response monitoring at the level of the serotonin 1a receptor system. |
2010-06-21 |
2023-08-12 |
human |
| Sérgio Murilo Steffens, Danielle Beckman, Moacir Serralvo Faria, José Marino-Neto, Marta Aparecida Paschoalin. WAY100635 blocks the hypophagia induced by 8-OH-DPAT in the hypothalamic nuclei. Physiology & behavior. vol 99. issue 5. 2010-06-09. PMID:20138904. |
this study examined the influence of pretreatment with n-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-n-(2-pyridinyl) cyclohexane carboxamide maleate (way100635, full 5-ht1a receptor antagonist, 37 nmol) on feeding effects evoked by local injections of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-oh-dpat, 5-ht(1a) and 5-ht(7) receptor agonist, 6 nmol) into the lh and into the arc of female rats adapted to a wet mash diet (enriched with 10% sucrose), during diestrus or estrus. |
2010-06-09 |
2023-08-12 |
rat |
| I A Zimin, D A Abaimov, E A Budygin, Iu A Zolotarev, G I Kovale. [Role of the brain dopaminergic and serotoninergic systems in psychopharmacological effects of ladasten and sydnocarb]. Eksperimental'naia i klinicheskaia farmakologiia. vol 73. issue 2. 2010-05-04. PMID:20369592. |
it is established that both drugs do not produce any direct effects on dopamine d1, d2, and d3 receptors in rat striatum as well as on serotonin 5-ht1a and 5-ht2a receptors in rat frontal cortex in vitro. |
2010-05-04 |
2023-08-12 |
rat |
| Jens Benninghoff, Angela Gritti, Matteo Rizzi, Giuseppe Lamorte, Robert J Schloesser, Angelika Schmitt, Stefanie Robel, Just Genius, Rainald Moessner, Peter Riederer, Husseini K Manji, Heinz Grunze, Dan Rujescu, Hans-Juergen Moeller, Klaus-Peter Lesch, Angelo Luigi Vescov. Serotonin depletion hampers survival and proliferation in neurospheres derived from adult neural stem cells. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:20010549. |
5-ht action on ansc was mediated predominantly by the serotonin receptor subtype 5-ht1a and, to a lesser extent, through the 5-ht2c (receptor) subtype, as shown by selectively antagonizing these receptors. |
2010-04-28 |
2023-08-12 |
mouse |
| L M Kozhevnikova, P V Avdoni. [Agonist 5HT1A-receptors of serotonin 8-OH-DPAT increase the power of collapse of the aorta and mesenteric artery in rats in the presence of endothelin-1 or vasopressin and cause vessel relaxation precollapsing with noradrenaline]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 1. 2010-04-27. PMID:20235428. |
agonist 5ht1a serotonin receptors 8-oh-dpat at 70-80% in rats relax the isolated aorta and mesenteric artery, precollapsed with noradrenaline. |
2010-04-27 |
2023-08-12 |
rat |
| Andrea Gogos, Perrin Kwek, Carolina Chavez, Maarten van den Buus. Estrogen treatment blocks 8-hydroxy-2-dipropylaminotetralin- and apomorphine-induced disruptions of prepulse inhibition: involvement of dopamine D1 or D2 or serotonin 5-HT1A, 5-HT2A, or 5-HT7 receptors. The Journal of pharmacology and experimental therapeutics. vol 333. issue 1. 2010-04-22. PMID:20042529. |
estrogen treatment blocks 8-hydroxy-2-dipropylaminotetralin- and apomorphine-induced disruptions of prepulse inhibition: involvement of dopamine d1 or d2 or serotonin 5-ht1a, 5-ht2a, or 5-ht7 receptors. |
2010-04-22 |
2023-08-12 |
rat |
| Jun-Xu Li, Wouter Koek, Kenner C Rice, Charles P Franc. Differential effects of serotonin 5-HT1A receptor agonists on the discriminative stimulus effects of the 5-HT2A receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rats and rhesus monkeys. The Journal of pharmacology and experimental therapeutics. vol 333. issue 1. 2010-04-22. PMID:20053932. |
differential effects of serotonin 5-ht1a receptor agonists on the discriminative stimulus effects of the 5-ht2a receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rats and rhesus monkeys. |
2010-04-22 |
2023-08-12 |
rat |
| Taro Kishi, Tomoko Tsunoka, Masashi Ikeda, Tsuyoshi Kitajima, Kunihiro Kawashima, Tomo Okochi, Takenori Okumura, Yoshio Yamanouchi, Yoko Kinoshita, Hiroshi Ujike, Toshiya Inada, Mitsuhiko Yamada, Naohisa Uchimura, Ichiro Sora, Masaomi Iyo, Norio Ozaki, Nakao Iwat. Serotonin 1A receptor gene is associated with Japanese methamphetamine-induced psychosis patients. Neuropharmacology. vol 58. issue 2. 2010-04-13. PMID:19747927. |
several investigations have reported associations the serotonin 1a (5-ht1a) receptor to schizophrenia and psychotic disorders, making 5-ht1a receptor gene (htr1a) an adequate candidate gene for the pathophysiology of schizophrenia and methamphetamine (meth)-induced psychosis. |
2010-04-13 |
2023-08-12 |
Not clear |
| Niamh Kieran, Xiao-Ming Ou, Abiye H Iy. Chronic social defeat downregulates the 5-HT1A receptor but not Freud-1 or NUDR in the rat prefrontal cortex. Neuroscience letters. vol 469. issue 3. 2010-04-12. PMID:20026183. |
the serotonin 1a receptor (5-ht1a) and its associated transcriptional regulators, five prime repressor element under dual repression (freud-1) and nuclear-deformed epidermal autoregulatory factor (nudr/deaf-1) have been previously found to be the repressors for 5-ht1a in the serotonergic raphe neurons, and are also altered in postmortem brains of individuals with major depressive disorder (mdd) and in rats exposed to chronic restraint stress. |
2010-04-12 |
2023-08-12 |
human |
| B Capuano, I T Crosby, F M McRobb, D A Taylor, A Vom, W W Blessin. JL13 has clozapine-like actions on thermoregulatory cutaneous blood flow in rats: Involvement of serotonin 5-HT1A and 5-HT2A receptor mechanisms. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 1. 2010-04-07. PMID:19878703. |
jl13 has clozapine-like actions on thermoregulatory cutaneous blood flow in rats: involvement of serotonin 5-ht1a and 5-ht2a receptor mechanisms. |
2010-04-07 |
2023-08-12 |
rat |
| Daniela Popa, Julie Cerdan, Christelle Repérant, Bruno P Guiard, Jean-Philippe Guilloux, Denis J David, Alain M Gardie. A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain. European journal of pharmacology. vol 628. issue 1-3. 2010-04-05. PMID:19944680. |
we report that the anxiolytic-like effects of fluoxetine correlate in time and amplitude with 5-ht1a autoreceptor desensitization, but neither with the extracellular levels of 5-ht in the raphe nuclei, nor in the hippocampus. |
2010-04-05 |
2023-08-12 |
mouse |