| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Susanne H M Gruber, Stefan Bren\\xc3\\xa. Social isolation increases number of newly proliferated cells in hippocampus in female flinders sensitive line rats. Hippocampus. vol 17. issue 12. 2008-02-29. PMID:17879375.' |
in an animal model of depression, flinders sensitive line rats, and sprague dawley controls we analyzed if 7 weeks of social isolation of adult animals affect the number of newly proliferated cells in the dentate gyrus or mrnas of neuropeptide y (npy), the npy-y1 receptor, nociceptin, bdnf, and the serotonin 5ht1a and 5ht2a receptors, which are molecules involved in hippocampal plasticity. |
2008-02-29 |
2023-08-12 |
rat |
| Henrik Stig Jørgense. Studies on the neuroendocrine role of serotonin. Danish medical bulletin. vol 54. issue 4. 2008-02-14. PMID:18208678. |
the 5-ht induced prl response is mediated via 5-ht1a, 5-ht2a, 5-ht2c and 5-ht3 receptors. |
2008-02-14 |
2023-08-12 |
rat |
| Henrik Stig Jørgense. Studies on the neuroendocrine role of serotonin. Danish medical bulletin. vol 54. issue 4. 2008-02-14. PMID:18208678. |
the acth response to 5-ht is mediated via 5-ht1a, 5-ht1b, 5-ht2a and 5-ht2c receptors and an involvement of the 5-ht4, 5-ht5 and 5-ht7 receptors is proposed. |
2008-02-14 |
2023-08-12 |
rat |
| Henrik Stig Jørgense. Studies on the neuroendocrine role of serotonin. Danish medical bulletin. vol 54. issue 4. 2008-02-14. PMID:18208678. |
peripheral secretion of avp upon stimulation with 5-ht is mediated via 5-ht2c, 5-ht4 and 5-ht7 receptors but not 5-ht1a receptors. |
2008-02-14 |
2023-08-12 |
rat |
| Johan Lundberg, Jacqueline Borg, Christer Halldin, Lars Fard. A PET study on regional coexpression of 5-HT1A receptors and 5-HTT in the human brain. Psychopharmacology. vol 195. issue 3. 2008-02-08. PMID:17874074. |
several lines of evidence suggest inter-dependency between the serotonin transporter (5-htt) and the 5ht1a receptor, two recognised targets for the treatment of anxiety and depression. |
2008-02-08 |
2023-08-12 |
human |
| Pia Weikop, Jan Kehr, Jørgen Scheel-Krüge. Reciprocal effects of combined administration of serotonin, noradrenaline and dopamine reuptake inhibitors on serotonin and dopamine levels in the rat prefrontal cortex: the role of 5-HT1A receptors. Journal of psychopharmacology (Oxford, England). vol 21. issue 8. 2008-01-29. PMID:17984160. |
reciprocal effects of combined administration of serotonin, noradrenaline and dopamine reuptake inhibitors on serotonin and dopamine levels in the rat prefrontal cortex: the role of 5-ht1a receptors. |
2008-01-29 |
2023-08-12 |
rat |
| Nami Tanaka-Gomi, Kouichi Yasuda, Masaaki Nakamura, Yoko Hasumi-Nakayama, Tetsuhiro Umemura, Susumu Tanaka, Kiyofumi Furusaw. Postnatal changes in 5HT and NK1 receptors in rat trigeminal motor nucleus and surroundings. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 25. issue 7. 2008-01-23. PMID:17942267. |
furthermore, 5ht1a and nk1 receptors displayed very similar patterns of expression, which may support the hypothesis that potentiation of serotonin and substance p are involved in excitability regulating trigeminal motor functions, including mastication and breathing. |
2008-01-23 |
2023-08-12 |
rat |
| Noreen Samad, Farhat Batool, Darakhshan J Halee. Neurochemical and behavioral effects of 8-OH-DPAT following exposure to restraint stress in rats. Pharmacological reports : PR. vol 59. issue 2. 2008-01-17. PMID:17556795. |
8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat), a selective 5-hydroxytryptamine 1a (serotonin; 5-ht1a) agonist was used to evaluate the role of somatodendritic and/or postsynaptic 5-ht1a receptors following exposure to restraint stress. |
2008-01-17 |
2023-08-12 |
rat |
| Takeo Ishiyama, Kumiko Tokuda, Tadashi Ishibashi, Akira Ito, Satoko Toma, Yukihiro Ohn. Lurasidone (SM-13496), a novel atypical antipsychotic drug, reverses MK-801-induced impairment of learning and memory in the rat passive-avoidance test. European journal of pharmacology. vol 572. issue 2-3. 2008-01-14. PMID:17662268. |
lurasidone (sm-13496) is a novel atypical antipsychotic with high affinities to dopamine d2, serotonin 5-ht7, 5-ht2a, 5-ht1a receptors and alpha2c adrenoceptor. |
2008-01-14 |
2023-08-12 |
rat |
| Alfredo Menese. Stimulation of 5-HT1A, 5-HT1B, 5-HT2A/2C, 5-HT3 and 5-HT4 receptors or 5-HT uptake inhibition: short- and long-term memory. Behavioural brain research. vol 184. issue 1. 2008-01-09. PMID:17692935. |
stimulation of 5-ht1a, 5-ht1b, 5-ht2a/2c, 5-ht3 and 5-ht4 receptors or 5-ht uptake inhibition: short- and long-term memory. |
2008-01-09 |
2023-08-12 |
Not clear |
| Bruno P Guiard, Jean-Philippe Guilloux, Christelle Reperant, Stephen P Hunt, Miklos Toth, Alain M Gardie. Substance P neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex. Molecular pharmacology. vol 72. issue 6. 2008-01-04. PMID:17890358. |
contrasting with its cortical effects, intraraphe sp injection increased 5-ht outflow in the drn in wild-type mice; this effect was potentiated by a local perfusion of the selective 5-ht1a antagonist n-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-n-2-pyridinylcyclohexanecarboxamide (way100635). |
2008-01-04 |
2023-08-12 |
mouse |
| Bruno P Guiard, Jean-Philippe Guilloux, Christelle Reperant, Stephen P Hunt, Miklos Toth, Alain M Gardie. Substance P neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex. Molecular pharmacology. vol 72. issue 6. 2008-01-04. PMID:17890358. |
these data support the hypothesis that sp-induced over-activation of 5-ht1a autoreceptors within the drn limits cortical 5-ht release. |
2008-01-04 |
2023-08-12 |
mouse |
| Sigeng Chen, Geoffrey C Owens, Kathryn L Crossin, David B Edelma. Serotonin stimulates mitochondrial transport in hippocampal neurons. Molecular and cellular neurosciences. vol 36. issue 4. 2008-01-04. PMID:17904380. |
administration of a 5-ht1a receptor antagonist inhibited mitochondrial movement, whereas addition of fluoxetine, a selective serotonin reuptake inhibitor, promoted mitochondrial movement. |
2008-01-04 |
2023-08-12 |
rat |
| Bella Smolin, Ehud Klein, Yishai Levy, Dorit Ben-Shacha. Major depression as a disorder of serotonin resistance: inference from diabetes mellitus type II. The international journal of neuropsychopharmacology. vol 10. issue 6. 2008-01-02. PMID:17250776. |
we review extensive supporting evidence from human studies and animal models of depression, including stress involvement in the aetiology of depression, evidence for increased synaptic serotonin and decreased 5-ht1a receptor activity. |
2008-01-02 |
2023-08-12 |
human |
| S M Davydova, G V Idov. [Presynaptic 5-HT1A receptors in immunomodulation]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 93. issue 10. 2007-12-31. PMID:18074789. |
the preliminary blockade of 5-ht1a receptor with a selective antagonist of 5-ht1a receptors way-100635 (0.1 mg/kg) prevented the immunostimulating effect of 5-ht 1a receptors agonist 8-oh-dpat, whereas way-100635 administration alone in the same dose didn't change the immune response. |
2007-12-31 |
2023-08-12 |
mouse |
| K Stachowicz, K Gołembiowska, M Sowa, G Nowak, E Chojnacka-Wójcik, A Pil. Anxiolytic-like action of MTEP expressed in the conflict drinking Vogel test in rats is serotonin dependent. Neuropharmacology. vol 53. issue 6. 2007-12-21. PMID:17870136. |
the obtained results suggest that the potential anxiolytic effect of the mglu5 receptor antagonist mtep is due to the increased serotonin release with subsequent activation of 5-ht2a/2c receptors, most probably located postsynaptically, but not by the 5-ht1a receptors. |
2007-12-21 |
2023-08-12 |
rat |
| Tina M Hallis, Andrew L Kopp, Jasmin Gibson, Connie S Lebakken, Michael Hancock, Kaitlyn Van Den Heuvel-Kramer, Tammy Turek-Etienn. An improved beta-lactamase reporter assay: multiplexing with a cytotoxicity readout for enhanced accuracy of hit identification. Journal of biomolecular screening. vol 12. issue 5. 2007-12-20. PMID:17517902. |
to demonstrate the improvement in hit confirmation, the multiplexed assay was used to perform a small-library screen (7728 compounds) for serotonin 5ht1a receptor antagonists. |
2007-12-20 |
2023-08-12 |
Not clear |
| Danuta Wasserman, Thomas Geijer, Marcus Sokolowski, Vsevolod Rozanov, Jerzy Wasserma. Nature and nurture in suicidal behavior, the role of genetics: some novel findings concerning personality traits and neural conduction. Physiology & behavior. vol 92. issue 1-2. 2007-12-06. PMID:17585962. |
additionally, we have results which give support to the findings of others, implicating the serotonin transporter and serotonin receptor 1a in suicidal behavior. |
2007-12-06 |
2023-08-12 |
Not clear |
| Sven Ove Ogren, Haleh Razani, Elin Elvander-Tottie, Jan Keh. The neuropeptide galanin as an in vivo modulator of brain 5-HT1A receptors: possible relevance for affective disorders. Physiology & behavior. vol 92. issue 1-2. 2007-12-06. PMID:17585970. |
this review summarizes results from experimental studies in rodents showing that in vivo galanin is a potent modulator of brain 5-ht transmission, and in particular 5-ht1a receptor-mediated functions. |
2007-12-06 |
2023-08-12 |
rat |
| Alfonso González, Fili Fazzino, Mirta Castillo, Salvador Mata, Lucimey Lim. Serotonin, 5-HT1A serotonin receptors and proliferation of lymphocytes in major depression patients. Neuroimmunomodulation. vol 14. issue 1. 2007-11-28. PMID:17700035. |
serotonin, 5-ht1a serotonin receptors and proliferation of lymphocytes in major depression patients. |
2007-11-28 |
2023-08-12 |
human |