| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kally C O'Reilly, Simon Trent, Sarah J Bailey, Michelle A Lan. 13-cis-Retinoic acid alters intracellular serotonin, increases 5-HT1A receptor, and serotonin reuptake transporter levels in vitro. Experimental biology and medicine (Maywood, N.J.). vol 232. issue 9. 2007-11-27. PMID:17895527. |
13-cis-retinoic acid alters intracellular serotonin, increases 5-ht1a receptor, and serotonin reuptake transporter levels in vitro. |
2007-11-27 |
2023-08-12 |
mouse |
| C Mannucci, A Pieratti, F Firenzuoli, A P Caputi, G Calapa. Serotonin mediates beneficial effects of Hypericum perforatum on nicotine withdrawal signs. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 14. issue 10. 2007-11-26. PMID:17689233. |
our results, show a significant increase of cortical 5-ht content in nm treated with h. perforatum, with a concomitant significant increase of 5-ht1a receptor. |
2007-11-26 |
2023-08-12 |
mouse |
| U Dannlowski, P Ohrmann, J Bauer, H Kugel, B T Baune, C Hohoff, A Kersting, V Arolt, W Heindel, J Deckert, T Suslo. Serotonergic genes modulate amygdala activity in major depression. Genes, brain, and behavior. vol 6. issue 7. 2007-11-20. PMID:17284168. |
this study used an imaging genomics approach to investigate amygdala activity in major depression as a function of common functional polymorphisms in the serotonin transporter gene (5-httlpr) and the serotonin receptor 1a gene (5-ht(1a)-1019c/g). |
2007-11-20 |
2023-08-12 |
Not clear |
| Alexandre O Fernandes da Silva, Luciane H Gargaglioni, Luiz G S Branc. 5-HT2A serotoninergic receptor in the locus coeruleus participates in the first phase of lipopolysaccharide-induced fever. Canadian journal of physiology and pharmacology. vol 85. issue 5. 2007-10-30. PMID:17632583. |
taken together, these results indicate that serotonin acting on 5-ht2a receptors in the lc mediates the first phase of the febrile response, whereas 5-ht1a receptors are not involved in the lipopolysaccharide-induced fever. |
2007-10-30 |
2023-08-12 |
Not clear |
| Marcio Versian. Ziprasidone in bipolar disorder. Expert opinion on pharmacotherapy. vol 7. issue 9. 2007-10-26. PMID:16732708. |
it has a unique receptor profile that includes high-affinity antagonist activity at 5-hydroxytryptamine (5-ht) 2a, d2, 1d and 2c receptors, a potent agonist activity at 5-ht1a receptors and a relatively high affinity for the 5-ht and noradrenaline transporters. |
2007-10-26 |
2023-08-12 |
Not clear |
| N K Popova, V S Naumenko, I Z Plyusnin. Involvement of brain serotonin 5-HT1A receptors in genetic predisposition to aggressive behavior. Neuroscience and behavioral physiology. vol 37. issue 6. 2007-10-26. PMID:17657435. |
involvement of brain serotonin 5-ht1a receptors in genetic predisposition to aggressive behavior. |
2007-10-26 |
2023-08-12 |
mouse |
| M S Clark, R A McDevitt, B J Hoplight, J F Neumaie. Chronic low dose ovine corticotropin releasing factor or urocortin II into the rostral dorsal raphe alters exploratory behavior and serotonergic gene expression in specific subregions of the dorsal raphe. Neuroscience. vol 146. issue 4. 2007-10-25. PMID:17467184. |
following behavioral testing, 5-ht1a, 5-ht1b, 5-ht transporter (sert), and tryptophan hydroxylase-2 (tph2) expression was examined through the drn by in situ hybridization. |
2007-10-25 |
2023-08-12 |
human |
| Ute Renner, Konstantin Glebov, Thorsten Lang, Ekaterina Papusheva, Saju Balakrishnan, Bernhard Keller, Diethelm W Richter, Reinhard Jahn, Evgeni Ponimaski. Localization of the mouse 5-hydroxytryptamine(1A) receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signaling. Molecular pharmacology. vol 72. issue 3. 2007-10-19. PMID:17540717. |
in the present study, we have used wild-type and palmitoylation-deficient mouse 5-hydroxytryptamine(1a) receptor (5-ht1a) receptors fused to the yellow fluorescent protein- and the cyan fluorescent protein (cfp)-tagged alpha(i3) subunit of heterotrimeric g-protein to study spatiotemporal distribution of the 5-ht1a-mediated signaling in living cells. |
2007-10-19 |
2023-08-12 |
mouse |
| M Møller, G Andersen, A Gjedd. Serotonin 5HT1A receptor availability and pathological crying after stroke. Acta neurologica Scandinavica. vol 116. issue 2. 2007-10-19. PMID:17661792. |
serotonin 5ht1a receptor availability and pathological crying after stroke. |
2007-10-19 |
2023-08-12 |
Not clear |
| Sâmia Regiane Lourenço Joca, Frederico Rogério Ferreira, Francisco Silveira Guimarãe. Modulation of stress consequences by hippocampal monoaminergic, glutamatergic and nitrergic neurotransmitter systems. Stress (Amsterdam, Netherlands). vol 10. issue 3. 2007-10-02. PMID:17613938. |
serotonin (5-ht) seems to exert a protective role in the hippocampus and attenuates the behavioural consequences of stress by activating 5-ht1a receptors in this structure. |
2007-10-02 |
2023-08-12 |
Not clear |
| Mette Møller, Steen Jakobsen, Albert Gjedd. Parametric and regional maps of free serotonin 5HT1A receptor sites in human brain as function of age in healthy humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 8. 2007-09-26. PMID:17251909. |
parametric and regional maps of free serotonin 5ht1a receptor sites in human brain as function of age in healthy humans. |
2007-09-26 |
2023-08-12 |
human |
| Jeannette M Watson, Lee A Dawso. Characterization of the potent 5-HT(1A/B) receptor antagonist and serotonin reuptake inhibitor SB-649915: preclinical evidence for hastened onset of antidepressant/anxiolytic efficacy. CNS drug reviews. vol 13. issue 2. 2007-09-21. PMID:17627673. |
it has been proven that selective serotonin reuptake inhibitors are effective antidepressants, but the delay to therapeutic onset of these agents is thought to be due to the time required for 5-ht1a, and possibly 5-ht1b, autoreceptors to desensitize. |
2007-09-21 |
2023-08-12 |
human |
| Jeannette M Watson, Lee A Dawso. Characterization of the potent 5-HT(1A/B) receptor antagonist and serotonin reuptake inhibitor SB-649915: preclinical evidence for hastened onset of antidepressant/anxiolytic efficacy. CNS drug reviews. vol 13. issue 2. 2007-09-21. PMID:17627673. |
therefore, an agent incorporating 5-ht reuptake inhibition coupled with 5-ht1a and/or 5-ht1b autoreceptor antagonism may provide a fast-acting clinical agent. |
2007-09-21 |
2023-08-12 |
human |
| Jeannette M Watson, Lee A Dawso. Characterization of the potent 5-HT(1A/B) receptor antagonist and serotonin reuptake inhibitor SB-649915: preclinical evidence for hastened onset of antidepressant/anxiolytic efficacy. CNS drug reviews. vol 13. issue 2. 2007-09-21. PMID:17627673. |
the current studies review the profile of sb-649915 (6-[(1-{2-[(2-methylquinolin-5-yl)oxy]ethyl}piperidin-4-yl)methyl]-2h-1,4-benzoxazin-3(4h)-one), a novel compound with high affinity for human (h) 5-ht1a and 5-ht1b receptors (pki values of 8.6 and 8.0, respectively) as well as the (h) 5-ht transporter (sert) (pki value of 9.3). |
2007-09-21 |
2023-08-12 |
human |
| Jeannette M Watson, Lee A Dawso. Characterization of the potent 5-HT(1A/B) receptor antagonist and serotonin reuptake inhibitor SB-649915: preclinical evidence for hastened onset of antidepressant/anxiolytic efficacy. CNS drug reviews. vol 13. issue 2. 2007-09-21. PMID:17627673. |
sb-649915 behaved as an antagonist at both 5-ht1a and 5-ht1b receptors in vitro and in vivo, reversing 5-ht, (+)8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat) and skf99101-induced functional/behavioral responses. |
2007-09-21 |
2023-08-12 |
human |
| Steven M Southwick, Meena Vythilingam, Dennis S Charne. The psychobiology of depression and resilience to stress: implications for prevention and treatment. Annual review of clinical psychology. vol 1. 2007-09-21. PMID:17716089. |
neurobiological factors that are discussed and contrasted include serotonin, the 5-ht1a receptor, polymorphisms of the 5-ht transporter gene, norepinephrine, alpha-2 adrenergic receptors, neuropeptide y, polymorphisms of the alpha-2 adrenergic gene, dopamine, corticotropin-releasing hormone (crh), dehydroepiandrosterone (dhea), cortisol, and crh receptors. |
2007-09-21 |
2023-08-12 |
Not clear |
| Yoshihisa Kitamura, Kozue Akiyama, Shinji Hashimoto, Kouhei Kitagawa, Hiromu Kawasaki, Kazuhiko Shibata, Kazuaki Shinomiya, Katsuya Suemaru, Hiroaki Araki, Toshiaki Sendo, Yutaka Gomit. Effects of imipramine on extracellular serotonin and noradrenaline concentrations in ACTH-treated rats. European journal of pharmacology. vol 566. issue 1-3. 2007-09-19. PMID:17459373. |
8-hydroxy-2-di-n-propylamino tetralin (8-oh-dpat), a 5-ht1a receptors full agonist, caused a significant decrease in extracellular 5-ht concentrations. |
2007-09-19 |
2023-08-12 |
rat |
| Yoshihisa Kitamura, Kozue Akiyama, Shinji Hashimoto, Kouhei Kitagawa, Hiromu Kawasaki, Kazuhiko Shibata, Kazuaki Shinomiya, Katsuya Suemaru, Hiroaki Araki, Toshiaki Sendo, Yutaka Gomit. Effects of imipramine on extracellular serotonin and noradrenaline concentrations in ACTH-treated rats. European journal of pharmacology. vol 566. issue 1-3. 2007-09-19. PMID:17459373. |
these findings suggest that chronic treatment with acth enhances the increasing effect release of 5-ht by imipramine through the desensitization of somatodendritic 5-ht1a autoreceptors. |
2007-09-19 |
2023-08-12 |
rat |
| D R Deng, S Djalali, M Höltje, G Grosse, T Stroh, I Voigt, H Kusserow, F Theuring, G Ahnert-Hilger, H Hörtnag. Embryonic and postnatal development of the serotonergic raphe system and its target regions in 5-HT1A receptor deletion or overexpressing mouse mutants. Neuroscience. vol 147. issue 2. 2007-09-18. PMID:17543467. |
the present data indicate that 5-ht1a receptor deficiency or overexpression is associated with increased 5-ht synthesis and turnover in the early postnatal period. |
2007-09-18 |
2023-08-12 |
mouse |
| Jussi Hirvonen, Jaana Kajander, Topias Allonen, Vesa Oikonen, Kjell Någren, Jarmo Hietal. Measurement of serotonin 5-HT1A receptor binding using positron emission tomography and [carbonyl-(11)C]WAY-100635-considerations on the validity of cerebellum as a reference region. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 27. issue 1. 2007-09-17. PMID:16685258. |
measurement of serotonin 5-ht1a receptor binding using positron emission tomography and [carbonyl-(11)c]way-100635-considerations on the validity of cerebellum as a reference region. |
2007-09-17 |
2023-08-12 |
human |