All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
K D Alex, E A Pehe. Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission. Pharmacology & therapeutics. vol 113. issue 2. 2007-04-19. PMID:17049611. several subtypes, including the 5-ht1a, 5-ht1b, 5-ht2a, 5-ht3 and 5-ht4 receptors, act to facilitate da release, while the 5-ht2c receptor mediates an inhibitory effect of 5-ht on da release. 2007-04-19 2023-08-12 Not clear
Peter J Lovell, Frank E Blaney, Caroline J Goodacre, Claire M Scott, Paul W Smith, Kathryn R Starr, Kevin M Thewlis, Antonio K K Vong, Simon E Ward, Jeannette M Watso. 3,4-Dihydro-2H-benzoxazinones as dual-acting 5-HT1A receptor antagonists and serotonin reuptake inhibitors. Bioorganic & medicinal chemistry letters. vol 17. issue 4. 2007-04-13. PMID:17129726. 3,4-dihydro-2h-benzoxazinones as dual-acting 5-ht1a receptor antagonists and serotonin reuptake inhibitors. 2007-04-13 2023-08-12 rat
Justin H Turner, Maria N Garnovskaya, John R Raymon. Serotonin 5-HT1A receptor stimulates c-Jun N-terminal kinase and induces apoptosis in Chinese hamster ovary fibroblasts. Biochimica et biophysica acta. vol 1773. issue 3. 2007-04-10. PMID:17208318. serotonin 5-ht1a receptor stimulates c-jun n-terminal kinase and induces apoptosis in chinese hamster ovary fibroblasts. 2007-04-10 2023-08-12 Not clear
Marie Cahir, Tara Ardis, Gavin P Reynolds, Stephen J Coope. Acute and chronic tryptophan depletion differentially regulate central 5-HT1A and 5-HT 2A receptor binding in the rat. Psychopharmacology. vol 190. issue 4. 2007-04-06. PMID:17124620. acute and chronic tryptophan depletion differentially regulate central 5-ht1a and 5-ht 2a receptor binding in the rat. 2007-04-06 2023-08-12 rat
Naphtali A O'Connor, David A Paisner, Donna Huryn, Kenneth J She. Screening of 5-HT1A receptor antagonists using molecularly imprinted polymers. Journal of the American Chemical Society. vol 129. issue 6. 2007-04-03. PMID:17284006. in an effort to evaluate the relationship between mips and native receptors, imprinted polymers for way-100635, an antagonist of the serotonin (5-ht) receptor subtype 5-ht1a were prepared. 2007-04-03 2023-08-12 Not clear
Stephane Cuisiat, Nathalie Bourdiol, Vincent Lacharme, Adrian Newman-Tancredi, Francis Colpaert, Bernard Vache. Towards a new generation of potential antipsychotic agents combining D2 and 5-HT1A receptor activities. Journal of medicinal chemistry. vol 50. issue 4. 2007-03-27. PMID:17300168. we report the discovery and the synthesis of novel, potential antipsychotic compounds combining potent dopamine d2 receptor antagonist and serotonin 5-ht1a receptor agonist properties in the same molecule. 2007-03-27 2023-08-12 rat
Jean-Claude Martel, Anne-Marie Ormière, Nathalie Leduc, Marie-Bernadette Assié, Didier Cussac, Adrian Newman-Tancred. Native rat hippocampal 5-HT1A receptors show constitutive activity. Molecular pharmacology. vol 71. issue 3. 2007-03-22. PMID:17167032. under these conditions, 5-ht and the prototypic selective 5-ht1a agonist (+)8-hydroxy-2-(di-n-propylamino)tetralin [(+)-8-oh-dpat] both stimulated [35s]gtpgammas binding to galphao to a similar extent, raising binding to approximately 130% of basal with pec50 values of 7.91 and 7.87, respectively. 2007-03-22 2023-08-12 human
Jean-Claude Martel, Anne-Marie Ormière, Nathalie Leduc, Marie-Bernadette Assié, Didier Cussac, Adrian Newman-Tancred. Native rat hippocampal 5-HT1A receptors show constitutive activity. Molecular pharmacology. vol 71. issue 3. 2007-03-22. PMID:17167032. these data provide the first demonstration that native rat serotonin 5-ht1a receptors can exhibit constitutive activity in vitro. 2007-03-22 2023-08-12 human
Jordanna E Bermack, Guy Debonne. Effects of OPC-14523, a combined sigma and 5-HT1a ligand, on pre- and post-synaptic 5-HT1a receptors. Journal of psychopharmacology (Oxford, England). vol 21. issue 1. 2007-03-16. PMID:16533864. we have previously demonstrated that opc produces an increase in 5-ht neurotransmission and a decreased response of 5-ht neurons to the acute administration of paroxetine in the drn, an effect that appears to be mediated by opc's 5-ht1a receptor affinity. 2007-03-16 2023-08-12 rat
Yoshihisa Kitamura, Kouhei Kitagawa, Yoshika Fujitani, Kazuhiko Shibata, Hiroaki Araki, Toshiaki Sendou, Yutaka Gomit. The 5-HT1A receptor full agonist, 8-OH-DPAT inhibits ACTH-induced 5-HT2A receptor hyperfunction in rats: involvement of 5-HT1A receptors in the DOI-induced wet-dog shakes in ACTH-treated rats. Biological & pharmaceutical bulletin. vol 30. issue 1. 2007-03-13. PMID:17202670. we examined the influence of 8-hydroxy-2-di-n-propylamino tetralin (8-oh-dpat), a serotonin 1a (5-ht1a) receptor full agonist, on the wet-dog shake response induced by the (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (doi), a 5-ht2a receptor agonist, in adrenocorticotropic hormone (acth)-treated rats. 2007-03-13 2023-08-12 rat
John S Markowitz, C Lindsay DeVane, Linda K Pestreich, Kennerly S Patrick, Rafael Muni. A comprehensive in vitro screening of d-, l-, and dl-threo-methylphenidate: an exploratory study. Journal of child and adolescent psychopharmacology. vol 16. issue 6. 2007-03-01. PMID:17201613. although binding affinity was not demonstrable at the serotonin (5-ht) transporter site (sert), novel findings of the study included affinity for the 5-ht1a and 5-ht2b receptor sites for both d- and l-mph, with d-mph exerting by far the most predominant effects at these sites. 2007-03-01 2023-08-12 Not clear
M Bliziotes, A Eshleman, B Burt-Pichat, X-W Zhang, J Hashimoto, K Wiren, C Chen. Serotonin transporter and receptor expression in osteocytic MLO-Y4 cells. Bone. vol 39. issue 6. 2007-02-20. PMID:16884969. the clonal murine osteocytic cell line, mlo-y4, demonstrates expression of the serotonin transporter (5-htt), and the 5-ht1a, and 5-ht2a receptors by real-time rt-pcr and immunoblot analysis. 2007-02-20 2023-08-12 human
Justin H Turner, Maria N Garnovskaya, Sonya D Coaxum, Tamara M Vlasova, Margarita Yakutovich, David M Lefler, John R Raymon. Ca2+-calmodulin and janus kinase 2 are required for activation of sodium-proton exchange by the Gi-coupled 5-hydroxytryptamine 1a receptor. The Journal of pharmacology and experimental therapeutics. vol 320. issue 1. 2007-02-12. PMID:17050776. in this work, we present evidence that stimulation of the 5-hydroxytryptamine 1a (5-ht1a) receptor results in the formation of a signaling complex that includes activated janus kinase 2 (jak2), ca2+/calmodulin (cam), and nhe-1, and which involves tyrosine phosphorylation of cam. 2007-02-12 2023-08-12 Not clear
Wiesław Jerzy Cubała, Jerzy Landowsk. [Serotoninergic system and limbic-hypothalamic-pituitary-adrenal axis (LHPA axis) in depression]. Psychiatria polska. vol 40. issue 3. 2007-02-08. PMID:17037809. in depression, the 5-ht system exhibits impaired presynaptic activity of 5-ht neurones, an increased activity of central postsynaptic 5-ht2a receptors, decreased activity of postsynaptic 5-ht1a receptors and altered synaptic 5-ht uptake. 2007-02-08 2023-08-12 Not clear
Jeffrey C Glennon, Guus Van Scharrenburg, Eric Ronken, Mayke B Hesselink, Jan-Hendrik Reinders, Martina Van Der Neut, Stephen K Long, Rolf W Feenstra, Andrew C McCrear. In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist. Synapse (New York, N.Y.). vol 60. issue 8. 2007-01-30. PMID:17001660. in vitro characterization of slv308 (7-[4-methyl-1-piperazinyl]-2(3h)-benzoxazolone, monohydrochloride): a novel partial dopamine d2 and d3 receptor agonist and serotonin 5-ht1a receptor agonist. 2007-01-30 2023-08-12 human
Hitoshi Kita, Satomi Chiken, Yoshihisa Tachibana, Atsushi Namb. Serotonin modulates pallidal neuronal activity in the awake monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 1. 2007-01-29. PMID:17202474. previous anatomical studies and in vitro physiological studies in other brain areas have suggested the following possibilities: (1) 5-ht suppresses gabaergic inhibition through presynaptic 5-ht1b receptors; (2) 5-ht decreases the firing of pallidal neurons through postsynaptic 5-ht1a receptors; and (3) 5-ht postsynaptically excites pallidal neurons through activation of 5-ht2c, 5-ht4, or 5-ht7 receptors. 2007-01-29 2023-08-12 monkey
Hitoshi Kita, Satomi Chiken, Yoshihisa Tachibana, Atsushi Namb. Serotonin modulates pallidal neuronal activity in the awake monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 1. 2007-01-29. PMID:17202474. although in vivo experiments could not conclusively determine the receptor types or the active sites involved in the observed effects, the results suggested the following possibilities: (1) 5-ht strongly suppresses gabaergic inhibition probably through 5-ht1b receptors; (2) in the external pallidal segment, the suppression may involve additional receptors or mechanisms; and (3) 5-ht suppresses glutamatergic excitation probably through 5-ht1a (and not 5-ht1b) receptors. 2007-01-29 2023-08-12 monkey
Damien Carrel, Michel Hamon, Michèle Darmo. Role of the C-terminal di-leucine motif of 5-HT1A and 5-HT1B serotonin receptors in plasma membrane targeting. Journal of cell science. vol 119. issue Pt 20. 2007-01-23. PMID:17003106. role of the c-terminal di-leucine motif of 5-ht1a and 5-ht1b serotonin receptors in plasma membrane targeting. 2007-01-23 2023-08-12 Not clear
Damien Carrel, Michel Hamon, Michèle Darmo. Role of the C-terminal di-leucine motif of 5-HT1A and 5-HT1B serotonin receptors in plasma membrane targeting. Journal of cell science. vol 119. issue Pt 20. 2007-01-23. PMID:17003106. the 5-ht1a and 5-ht1b serotonin receptors exhibit different subcellular localizations in neurons. 2007-01-23 2023-08-12 Not clear
Klas Nordlind, Kristoffer Thorslund, Solbritt Lonne-Rahm, Sheila Mohabbati, Timea Berki, Marisela Morales, Efrain C Azmiti. Expression of serotonergic receptors in psoriatic skin. Archives of dermatological research. vol 298. issue 3. 2006-12-22. PMID:16794822. distribution of serotonin receptors was studied in involved and noninvolved skin in patients with psoriasis and compared to normal skin, by using immunohistochemistry and antibodies to 5-ht1a, 5-ht2a and 5-ht3 receptors (r). 2006-12-22 2023-08-12 Not clear