All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
Valiya Veettil Mohanan, Reas Khan, C S Paulos. Hypothalamic 5-HT functional regulation through 5-HT1A and 5-HT2C receptors during pancreatic regeneration. Life sciences. vol 78. issue 14. 2006-04-14. PMID:16253282. the pancreatic regeneration was evaluated by 5-ht content, 5-ht1a and 5-ht2c receptor gene expression in the hypothalamus of sham operated, 72 h and 7 days pancreatectomised rats. 2006-04-14 2023-08-12 rat
Alexis Evrard, Nicolas Barden, Michel Hamon, Joëlle Adrie. Glucocorticoid receptor-dependent desensitization of 5-HT1A autoreceptors by sleep deprivation: studies in GR-i transgenic mice. Sleep. vol 29. issue 1. 2006-04-14. PMID:16453979. in animals, sleep deprivation and pharmacologic treatment with antidepressants exert similar effects on 5-ht neurotransmission, notably functional desensitization of 5-ht1a autoreceptors located on 5-ht neurons in the dorsal raphe nucleus (drn). 2006-04-14 2023-08-12 mouse
Youichirou Ootsuka, William W Blessin. Thermogenesis in brown adipose tissue: increase by 5-HT2A receptor activation and decrease by 5-HT1A receptor activation in conscious rats. Neuroscience letters. vol 395. issue 2. 2006-04-13. PMID:16293365. body temperature is decreased by 5-hydroxytryptamine 1a (5-ht1a) agonists and increased by 5-ht2a agonists. 2006-04-13 2023-08-12 rat
Berangere Gruwez, Alain Dauphin, Michel To. A mathematical model for paroxetine antidepressant effect time course and its interaction with pindolol. Journal of pharmacokinetics and pharmacodynamics. vol 32. issue 5-6. 2006-04-13. PMID:16307210. building on a set-point model described previously for the hypothermic effect of 5-ht agonists, we have developed a model based on the concept of homeostatic control mechanisms, in which ssris exert their antidepressant effect by increasing the transduction set-point of the postsynaptic 5-ht1a receptor, and pindolol exerts its effect by increasing the rate of feedback mechanisms. 2006-04-13 2023-08-12 Not clear
Gerald Holtmann, Nicholas J Talle. Hypothesis driven research and molecular mechanisms in functional dyspepsia: the beginning of a beautiful friendship in research and practice? The American journal of gastroenterology. vol 101. issue 3. 2006-04-10. PMID:16542295. other carefully selected putative genes including polymorphisms in the alpha2a adrenoreceptor, the serotonin reuptake transporter, and the 5-ht1a receptor were not associated. 2006-04-10 2023-08-12 Not clear
Cyndy Davis Sanberg, Floretta L Jones, Viet H Do, Dario Dieguez, Brian E Derric. 5-HT1a receptor antagonists block perforant path-dentate LTP induced in novel, but not familiar, environments. Learning & memory (Cold Spring Harbor, N.Y.). vol 13. issue 1. 2006-04-04. PMID:16452654. here we investigate the contribution of serotonin and 5-ht1a receptors to the novelty-mediated enhancement of ltp. 2006-04-04 2023-08-12 Not clear
Cyndy Davis Sanberg, Floretta L Jones, Viet H Do, Dario Dieguez, Brian E Derric. 5-HT1a receptor antagonists block perforant path-dentate LTP induced in novel, but not familiar, environments. Learning & memory (Cold Spring Harbor, N.Y.). vol 13. issue 1. 2006-04-04. PMID:16452654. moreover, activation of raphe 5-ht1a autoreceptors, which inhibits serotonin release, attenuated ltp induction even in familiar environments. 2006-04-04 2023-08-12 Not clear
Cyndy Davis Sanberg, Floretta L Jones, Viet H Do, Dario Dieguez, Brian E Derric. 5-HT1a receptor antagonists block perforant path-dentate LTP induced in novel, but not familiar, environments. Learning & memory (Cold Spring Harbor, N.Y.). vol 13. issue 1. 2006-04-04. PMID:16452654. together, these data suggest that serotonin and dentate 5-ht1a receptors play a permissive role in dentate ltp induction, particularly in novel conditions, and presumably, during the encoding of novel, hippocampus-relevant information. 2006-04-04 2023-08-12 Not clear
Howard Choi, Wei-Lee Liao, Kimberly M Newton, Renna C Onario, Allyson M King, Federico C Desilets, Eric J Woodard, Marc E Eichler, Walter R Frontera, Sunil Sabharwal, Yang D Ten. Respiratory abnormalities resulting from midcervical spinal cord injury and their reversal by serotonin 1A agonists in conscious rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 18. 2006-03-23. PMID:15872102. because serotonin is involved in respiration-related neuroplasticity, we investigated the impact of activating 5-ht1a receptors on post-c5 sci respiratory dysfunction. 2006-03-23 2023-08-12 human
Dahui Zhou, Boyd L Harrison, Uresh Shah, Terrance H Andree, Geoffrey A Hornby, Rosemary Scerni, Lee E Schechter, Deborah L Smith, Kelly M Sullivan, Richard E Mewsha. Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinity. Bioorganic & medicinal chemistry letters. vol 16. issue 5. 2006-03-23. PMID:16332439. part 5: 3,4-dihydro-2h-benzo[1,4]oxazine derivatives with dual 5-ht1a receptor and serotonin transporter affinity. 2006-03-23 2023-08-12 Not clear
Sean P David, Naga Venkatesha Murthy, Eugenii A Rabiner, Marcus R Munafó, Elaine C Johnstone, Robyn Jacob, Robert T Walton, Paul M Grasb. A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 10. 2006-03-02. PMID:15758168. a functional genetic variation of the serotonin (5-ht) transporter affects 5-ht1a receptor binding in humans. 2006-03-02 2023-08-12 human
Sean P David, Naga Venkatesha Murthy, Eugenii A Rabiner, Marcus R Munafó, Elaine C Johnstone, Robyn Jacob, Robert T Walton, Paul M Grasb. A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 10. 2006-03-02. PMID:15758168. in the pet group, we also studied the influence of a common variable number tandem repeat polymorphism [short (s) and long (l) alleles] of the 5-ht transporter (5-htt) gene on 5-ht1a receptor density. 2006-03-02 2023-08-12 human
Woo-Kyu Park, Daeyoung Jeong, Heeyeong Cho, Seong Jin Lee, Mi Young Cha, Ae Nim Pae, Kyung Il Choi, Hun Yeong Koh, Jae Yang Kon. KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia. Pharmacology, biochemistry, and behavior. vol 82. issue 2. 2006-03-02. PMID:16216322. the present results, therefore, suggest that kkha-761 is a potent antipsychotic agent with combined dopamine d3 and serotonin 5-ht1a receptors modulation activity, which may further enhance its therapeutic potential for anxiety, psychotic depression, and other related disorders. 2006-03-02 2023-08-12 mouse
A Khan, F Batool, D J Halee. Behavioral effects of 8-OH-DPAT in single and repeated haloperidol injected rats. Pakistan journal of pharmaceutical sciences. vol 14. issue 2. 2006-03-01. PMID:16414856. the serotonin (5ht1a) receptor agonist 8-oh-dpat has been reported to attenuate extrapyramidal side effects of haloperidol. 2006-03-01 2023-08-12 rat
Erum Shireen, Qurrat-ul-Ain, Farhat Batool, Z S Saify, Darakhshan J Halee. Neurochemical effects of 8-hydroxy-2-di-n-propylamino tetralin in rats treated with haloperidol. Pakistan journal of pharmaceutical sciences. vol 15. issue 1. 2006-03-01. PMID:16414870. in view of a possible role of presynaptic serotonin (5-hydroxytryptamine, 5-ht) receptors in the precipitation of extrapyramidal side effects (eps), the present study was designed to investigate the neurochemical effects of a selective 5-ht1a ligand, 8-hydroxy-2- (di-n-propylamino) tetralin (8-oh-dpat) in rats following single (5 mg/kg) and repeated (two-times a day for 9 days at dosage of 5mg/kg) haloperidol administration. 2006-03-01 2023-08-12 rat
Nicolas Costes, Isabelle Merlet, Karine Ostrowsky, Isabelle Faillenot, Franck Lavenne, Luc Zimmer, Philippe Ryvlin, Didier Le Bar. A 18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 46. issue 12. 2006-02-27. PMID:16330560. 2'-methoxyphenyl-(n-2'-pyridinyl)-p-18f-fluoro-benzamidoethylpiperazine (18f-mppf) is a specific serotonin 5-ht1a antagonist pet tracer recently characterized, modeled, and used for clinical research to explore abnormalities in the serotoninergic system. 2006-02-27 2023-08-12 Not clear
Leith C R Meyer, Andrea Fuller, Duncan Mitchel. Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 290. issue 2. 2006-02-23. PMID:16166206. neurophysiological studies have shown that serotonergic ligands that bind to 5-ht1a, 5-ht7, and 5-ht4 serotonin receptors in brain stem have beneficial effects on respiratory neurons during opioid-induced respiratory depression. 2006-02-23 2023-08-12 Not clear
Eunice Y Yuen, Qian Jiang, Paul Chen, Zhenglin Gu, Jian Feng, Zhen Ya. Serotonin 5-HT1A receptors regulate NMDA receptor channels through a microtubule-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 23. 2006-02-17. PMID:15944377. serotonin 5-ht1a receptors regulate nmda receptor channels through a microtubule-dependent mechanism. 2006-02-17 2023-08-12 Not clear
Mateusz Nowak, Marcin Kołaczkowski, Maciej Pawłowski, Andrzej J Bojarsk. Homology modeling of the serotonin 5-HT1A receptor using automated docking of bioactive compounds with defined geometry. Journal of medicinal chemistry. vol 49. issue 1. 2006-02-16. PMID:16392805. homology modeling of the serotonin 5-ht1a receptor using automated docking of bioactive compounds with defined geometry. 2006-02-16 2023-08-12 Not clear
Suzana Uzun, Oliver Kozumplik, Ninoslav Mimica, Vera Folnegović-Smal. Aripiprazole: an overview of a novel antipsychotic. Psychiatria Danubina. vol 17. issue 1-2. 2006-02-15. PMID:16395846. aripiprazole exhibits high affinity for dopamine d2 and d3, serotonin 5-ht1a and 5-ht2a receptors, moderate affinity for dopamine d4, serotonin 5-ht2c and 5-ht7, alpha1-adrenergic and histamine h1 receptors. 2006-02-15 2023-08-12 Not clear