| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marie-Bernadette Assié, Véronique Ravailhe, Valérie Faucillon, Adrian Newman-Tancred. Contrasting contribution of 5-hydroxytryptamine 1A receptor activation to neurochemical profile of novel antipsychotics: frontocortical dopamine and hippocampal serotonin release in rat brain. The Journal of pharmacology and experimental therapeutics. vol 315. issue 1. 2005-11-28. PMID:15987834. |
we employed microdialysis coupled to high pressure liquid chromatography with electrochemical detection to examine 5-ht1a receptor activation in the modulation of extracellular dopamine in medial prefrontal cortex and serotonin in hippocampus of freely moving rats. |
2005-11-28 |
2023-08-12 |
rat |
| Marie-Bernadette Assié, Véronique Ravailhe, Valérie Faucillon, Adrian Newman-Tancred. Contrasting contribution of 5-hydroxytryptamine 1A receptor activation to neurochemical profile of novel antipsychotics: frontocortical dopamine and hippocampal serotonin release in rat brain. The Journal of pharmacology and experimental therapeutics. vol 315. issue 1. 2005-11-28. PMID:15987834. |
hippocampal 5-ht was decreased by bifeprunox, ssr181507, slv313, sarizotan, and nemonapride, effects similar to those seen with the 5-ht1a agonist, (+)-8-hydroxy-2-(di-n-propylamino)tetralin [(+)8-oh-dpat], consistent with activation of 5-ht1a autoreceptors. |
2005-11-28 |
2023-08-12 |
rat |
| Daniel O Kellett, S Clare Stanford, Benedito H Machado, David Jordan, Andrew G Ramag. Effect of 5-HT depletion on cardiovascular vagal reflex sensitivity in awake and anesthetized rats. Brain research. vol 1054. issue 1. 2005-11-14. PMID:16054601. |
antagonism of central 5-ht1a and 5-ht7 receptors inhibits reflex-evoked vagal bradycardias indicating that 5-ht is released during these reflexes. |
2005-11-14 |
2023-08-12 |
rat |
| Joanna I Udo de Haes, Thomas I F H Cremers, Fokko-J Bosker, Folkert Postema, Theodora D Tiemersma-Wegman, Johan A den Boe. Effect of increased serotonin levels on [18F]MPPF binding in rat brain: fenfluramine vs the combination of citalopram and ketanserin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 9. 2005-11-07. PMID:15827572. |
[18f]mppf is a selective serotonin-1a (5-ht1a) receptor antagonist and may be used to measure changes in the functional levels of serotonin (5-ht). |
2005-11-07 |
2023-08-12 |
rat |
| M Lee, U F Bailer, G K Frank, S E Henry, C C Meltzer, J C Price, C A Mathis, K T Putnam, R E Ferrell, A R Hariri, W H Kay. Relationship of a 5-HT transporter functional polymorphism to 5-HT1A receptor binding in healthy women. Molecular psychiatry. vol 10. issue 8. 2005-10-27. PMID:15940302. |
relationship of a 5-ht transporter functional polymorphism to 5-ht1a receptor binding in healthy women. |
2005-10-27 |
2023-08-12 |
Not clear |
| Theodore A Slotkin, Frederic J Seidle. The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent. Brain research. Developmental brain research. vol 158. issue 1-2. 2005-10-27. PMID:16024092. |
to determine if these changes are permanent, we administered 1 mg/kg of cpf daily to neonatal rats on postnatal days 1-4, a regimen devoid of systemic toxicity, and examined 5ht synaptic markers at 5 months of age: radioligand binding to 5ht1a and 5ht2 receptors and to the 5ht transporter. |
2005-10-27 |
2023-08-12 |
rat |
| Klaus-Peter Lesc. Serotonergic gene inactivation in mice: models for anxiety and aggression? Novartis Foundation symposium. vol 268. 2005-10-27. PMID:16206878. |
in particular, phenotypic changes in mice bearing inactivation mutations of 5-ht1a and 5-ht1b receptors, 5-ht transporter, 5-ht neuron-specific transcription factor pet1, monoamine oxidase a and genes related to 5-ht signalling will be discussed and major findings highlighted. |
2005-10-27 |
2023-08-12 |
mouse |
| E Baca, J R Azanza, J Giner, J Saiz-Ruiz, J Vallejo, T Diez, M Madriga. Ziprasidone: from pharmacology to the clinical practice. One year of experience. Actas espanolas de psiquiatria. vol 33. issue 5. 2005-10-25. PMID:16155814. |
moreover, its anti-depressive activity and its non-sedative profile have been confirmed, with a favorable effect on attention and other cognitive functions of the patient, according to its high affinity for 5ht1a and d1 receptors and the inhibition of serotonin and noradrenaline re-uptake. |
2005-10-25 |
2023-08-12 |
Not clear |
| William Bara-Jimenez, Francesco Bibbiani, Michael J Morris, Tzvetelina Dimitrova, Abdullah Sherzai, Maral M Mouradian, Thomas N Chas. Effects of serotonin 5-HT1A agonist in advanced Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 20. issue 8. 2005-10-19. PMID:15791634. |
effects of serotonin 5-ht1a agonist in advanced parkinson's disease. |
2005-10-19 |
2023-08-12 |
Not clear |
| William Bara-Jimenez, Francesco Bibbiani, Michael J Morris, Tzvetelina Dimitrova, Abdullah Sherzai, Maral M Mouradian, Thomas N Chas. Effects of serotonin 5-HT1A agonist in advanced Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 20. issue 8. 2005-10-19. PMID:15791634. |
if 5-ht1a autoreceptors regulate dopamine as well as serotonin release, in parkinsonian patients inhibition of striatal serotonergic neuron firing might help maintain more physiological intrasynaptic dopamine concentrations and thus ameliorate motor fluctuations and dyskinesias. |
2005-10-19 |
2023-08-12 |
Not clear |
| M C Buhot, G Malleret, L Seg. Serotonin receptors and cognitive behaviour--an update. IDrugs : the investigational drugs journal. vol 2. issue 5. 2005-10-13. PMID:16155845. |
this is made evident after administration of 5-ht(2a/2c), and 5-ht4 receptor agonists, or 5-ht1a, 5-ht3 and probably 5-ht1b receptor antagonists. |
2005-10-13 |
2023-08-12 |
mouse |
| L Arboreliu. 5-HT1A receptor antagonists as putative adjuvants to antidepressants: preclinical and clinical evidence. IDrugs : the investigational drugs journal. vol 2. issue 2. 2005-10-13. PMID:16160947. |
recently, the hypothesis was advanced that addition of a serotonin 1a (5-ht1a) receptor antagonist may shorten the latency to antidepressant action of selective serotonin reuptake inhibitors (ssris) as well as increase their efficacy in the treatment of depression. |
2005-10-13 |
2023-08-12 |
Not clear |
| L Arboreliu. 5-HT1A receptor antagonists as putative adjuvants to antidepressants: preclinical and clinical evidence. IDrugs : the investigational drugs journal. vol 2. issue 2. 2005-10-13. PMID:16160947. |
this hypothesis is based on preclinical findings showing that the purported increase in 5-ht concentrations in terminal regions produced by acute administration of ssris is hampered by a concomitant increase in 5-ht levels in cell body area leading to decreased serotonergic cell firing due to increased stimulation of inhibitory 5-ht1a autoreceptors. |
2005-10-13 |
2023-08-12 |
Not clear |
| L Arboreliu. 5-HT1A receptor antagonists as putative adjuvants to antidepressants: preclinical and clinical evidence. IDrugs : the investigational drugs journal. vol 2. issue 2. 2005-10-13. PMID:16160947. |
in this review data are presented showing that adding a 5-ht1a receptor antagonist prevents this feedback inhibition of serotonergic cell firing and allows more 5-ht to be released. |
2005-10-13 |
2023-08-12 |
Not clear |
| Chie-Fang Hsiao, Nanping Wu, Scott H Chandle. Voltage-dependent calcium currents in trigeminal motoneurons of early postnatal rats: modulation by 5-HT receptors. Journal of neurophysiology. vol 94. issue 3. 2005-10-11. PMID:15972834. |
the effects of 5-ht were blocked by the 5-ht1a antagonist 1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine hydrobromide (nan-190) but not by ketanserin, a 5-ht(2/1c) antagonist. |
2005-10-11 |
2023-08-12 |
rat |
| Chie-Fang Hsiao, Nanping Wu, Scott H Chandle. Voltage-dependent calcium currents in trigeminal motoneurons of early postnatal rats: modulation by 5-HT receptors. Journal of neurophysiology. vol 94. issue 3. 2005-10-11. PMID:15972834. |
calcium current modulation by 5-ht1a receptors likely is an important mechanism to fine tune the input/output gain of tmns in response to small incoming synaptic inputs and accounts for some of the previously reported effects of 5-ht on tmn excitability during tonic and burst activity during oral-motor behavior. |
2005-10-11 |
2023-08-12 |
rat |
| Irina Knyshevski, Lesley A Ricci, Thomas E McCann, Richard H Mellon. Serotonin type-1A receptors modulate adolescent, cocaine-induced offensive aggression in hamsters. Physiology & behavior. vol 85. issue 2. 2005-10-04. PMID:15885719. |
this study examined whether the adolescent cocaine-induced aggressive response was modulated by serotonin type 1a (5ht1a) receptors. |
2005-10-04 |
2023-08-12 |
Not clear |
| Sharon Oleskevich, Kwong-Joo Leck, Klaus Matthaei, Ian A Hendr. Enhanced serotonin response in the hippocampus of Galphaz protein knock-out mice. Neuroreport. vol 16. issue 9. 2005-09-30. PMID:15931062. |
the serotonin-1a [5-hydroxytryptamine 1a (5ht1a)] receptor is important for emotional and homeostatic processes in the central nervous system. |
2005-09-30 |
2023-08-12 |
mouse |
| Thomas J Pucadyil, Shanti Kalipatnapu, Amitabha Chattopadhya. The serotonin1A receptor: a representative member of the serotonin receptor family. Cellular and molecular neurobiology. vol 25. issue 3-4. 2005-09-29. PMID:16075379. |
the serotonin1a (5-ht1a) receptor is the most extensively studied of the serotonin receptors and belongs to the large family of seven transmembrane domain g-protein coupled receptors. |
2005-09-29 |
2023-08-12 |
cattle |
| Dan-Qin Xiao, Juan-Xia Zhu, Jing-Shi Tang, Hong Ji. 5-hydroxytryptamine 1A (5-HT1A) but not 5-HT3 receptor is involved in mediating the nucleus submedius 5-HT-evoked antinociception in the rat. Brain research. vol 1046. issue 1-2. 2005-09-27. PMID:15869749. |
5-hydroxytryptamine 1a (5-ht1a) but not 5-ht3 receptor is involved in mediating the nucleus submedius 5-ht-evoked antinociception in the rat. |
2005-09-27 |
2023-08-12 |
rat |