| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C L Bethea, J M Streicher, S J Mirkes, R L Sanchez, A P Reddy, J L Camero. Serotonin-related gene expression in female monkeys with individual sensitivity to stress. Neuroscience. vol 132. issue 1. 2005-07-20. PMID:15780474. |
thus, all serotonin-related mrnas examined in the dorsal raphe to date were lower (sert, mao-a) or exhibited a lower trend (5ht1a, mao-b) in the stress sensitive animals, which probably reflects the lower number of serotonin neurons present. |
2005-07-20 |
2023-08-12 |
monkey |
| Christine M Andrews, Hank F Kung, Irwin Luck. The 5-HT1A receptor modulates the effects of cocaine on extracellular serotonin and dopamine levels in the nucleus accumbens. European journal of pharmacology. vol 508. issue 1-3. 2005-07-14. PMID:15680262. |
the 5-ht1a receptor modulates the effects of cocaine on extracellular serotonin and dopamine levels in the nucleus accumbens. |
2005-07-14 |
2023-08-12 |
Not clear |
| Christine M Andrews, Hank F Kung, Irwin Luck. The 5-HT1A receptor modulates the effects of cocaine on extracellular serotonin and dopamine levels in the nucleus accumbens. European journal of pharmacology. vol 508. issue 1-3. 2005-07-14. PMID:15680262. |
the regulation of extracellular levels of serotonin (5-ht) and dopamine in response to cocaine by 5-ht1a receptors was examined using in vivo microdialysis and the 5-ht1a receptor antagonist 4-(2'-methoxy-)-phenyl-1-[2'-(n-2''-pyridinyl)-p-fluorobenzamido-]ethyl-piperazine (p-mppf). |
2005-07-14 |
2023-08-12 |
Not clear |
| Christine M Andrews, Hank F Kung, Irwin Luck. The 5-HT1A receptor modulates the effects of cocaine on extracellular serotonin and dopamine levels in the nucleus accumbens. European journal of pharmacology. vol 508. issue 1-3. 2005-07-14. PMID:15680262. |
the reduction of 5-ht and dopamine levels by systemic cocaine during accumbal infusion was blocked by pretreatment with the 5-ht1a receptor antagonist p-mppf. |
2005-07-14 |
2023-08-12 |
Not clear |
| Christine M Andrews, Hank F Kung, Irwin Luck. The 5-HT1A receptor modulates the effects of cocaine on extracellular serotonin and dopamine levels in the nucleus accumbens. European journal of pharmacology. vol 508. issue 1-3. 2005-07-14. PMID:15680262. |
taken together, these findings suggest that the 5-ht1a autoreceptor acts to modulate the effects of cocaine on both 5-ht and dopamine levels in the nucleus accumbens. |
2005-07-14 |
2023-08-12 |
Not clear |
| Patrick Osei-Owusu, Amy James, James Crane, Karie E Scrogi. 5-Hydroxytryptamine 1A receptors in the paraventricular nucleus of the hypothalamus mediate oxytocin and adrenocorticotropin hormone release and some behavioral components of the serotonin syndrome. The Journal of pharmacology and experimental therapeutics. vol 313. issue 3. 2005-07-14. PMID:15743927. |
these data indicate that 5-ht1a receptor stimulation in the pvn mediates the characteristic neuroendocrine response to serotonin agonist challenge. |
2005-07-14 |
2023-08-12 |
rat |
| Masahiko Tomiyama, Tamaki Kimura, Tetsuya Maeda, Kazuya Kannari, Muneo Matsunaga, Masayuki Bab. A serotonin 5-HT1A receptor agonist prevents behavioral sensitization to L-DOPA in a rodent model of Parkinson's disease. Neuroscience research. vol 52. issue 2. 2005-07-13. PMID:15893579. |
a serotonin 5-ht1a receptor agonist prevents behavioral sensitization to l-dopa in a rodent model of parkinson's disease. |
2005-07-13 |
2023-08-12 |
rat |
| Masahiko Tomiyama, Tamaki Kimura, Tetsuya Maeda, Kazuya Kannari, Muneo Matsunaga, Masayuki Bab. A serotonin 5-HT1A receptor agonist prevents behavioral sensitization to L-DOPA in a rodent model of Parkinson's disease. Neuroscience research. vol 52. issue 2. 2005-07-13. PMID:15893579. |
we have shown that pretreatment with 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat), a 5-ht1a (5-hydroxytryptamine) receptor agonist, alleviates fluctuation of dopamine levels in the dopamine-denervated striatum of 6-hydroxydopamine-lesioned (hemiparkinsonian) rats after l-dopa treatment. |
2005-07-13 |
2023-08-12 |
rat |
| Qian Li, Andrew Holmes, Li Ma, Louis D Van de Kar, Francisca Garcia, Dennis L Murph. Medial hypothalamic 5-hydroxytryptamine (5-HT)1A receptors regulate neuroendocrine responses to stress and exploratory locomotor activity: application of recombinant adenovirus containing 5-HT1A sequences. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 48. 2005-07-12. PMID:15574737. |
medial hypothalamic 5-hydroxytryptamine (5-ht)1a receptors regulate neuroendocrine responses to stress and exploratory locomotor activity: application of recombinant adenovirus containing 5-ht1a sequences. |
2005-07-12 |
2023-08-12 |
mouse |
| Qian Li, Andrew Holmes, Li Ma, Louis D Van de Kar, Francisca Garcia, Dennis L Murph. Medial hypothalamic 5-hydroxytryptamine (5-HT)1A receptors regulate neuroendocrine responses to stress and exploratory locomotor activity: application of recombinant adenovirus containing 5-HT1A sequences. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 48. 2005-07-12. PMID:15574737. |
these mice also showed decreased density of 5-hydroxytryptamine (5-ht1a) receptors in the hypothalamus, amygdala, and dorsal raphe. |
2005-07-12 |
2023-08-12 |
mouse |
| C Mizrahi, A Stojanovic, M Urbina, I Carreira, L Lim. Differential cAMP levels and serotonin effects in blood peripheral mononuclear cells and lymphocytes from major depression patients. International immunopharmacology. vol 4. issue 8. 2005-07-11. PMID:15270025. |
this effect probably indicates the blockade of 5ht1a receptors and action of 5ht1a agonist on the other subtypes of serotonin receptors expressed on human lymphocytes. |
2005-07-11 |
2023-08-12 |
human |
| C Mizrahi, A Stojanovic, M Urbina, I Carreira, L Lim. Differential cAMP levels and serotonin effects in blood peripheral mononuclear cells and lymphocytes from major depression patients. International immunopharmacology. vol 4. issue 8. 2005-07-11. PMID:15270025. |
the present report indicates: (1) differential responses of immune cells from control individuals and depressed patients, with lower apparent adenylate cyclase activity in patient's cells; (2) variation in the population of cells, with responses to serotonergic agonists being lower in mononuclear cells and higher in lymphocytes from major depression patients; (3) increases of camp levels by serotonin and 5ht1a agonist in the patient's cells; and (4) evidence of impairment in serotonergic transduction systems in immune cells during depression. |
2005-07-11 |
2023-08-12 |
human |
| Michelle D Jones, Irwin Luck. Sex differences in the regulation of serotonergic transmission and behavior in 5-HT receptor knockout mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 6. 2005-07-11. PMID:15688089. |
in contrast, male and female 5-ht1a receptor knockout mice demonstrated reduced immobility compared with control mice, but the depletion of 5-ht with pcpa did not reverse the antidepressant-like phenotype. |
2005-07-11 |
2023-08-12 |
mouse |
| Juan Manuel Mancilla-Diaz, Rodrigo Erick Escartin-Perez, Veronica Elsa Lopez-Alonso, Benjamin Floran-Garduño, Jose Bernardo Romano-Camach. Role of 5-HT1A and 5-HT1B receptors in the hypophagic effect of 5-HT on the structure of feeding behavior. Medical science monitor : international medical journal of experimental and clinical research. vol 11. issue 3. 2005-07-11. PMID:15735557. |
role of 5-ht1a and 5-ht1b receptors in the hypophagic effect of 5-ht on the structure of feeding behavior. |
2005-07-11 |
2023-08-12 |
rat |
| Juan Manuel Mancilla-Diaz, Rodrigo Erick Escartin-Perez, Veronica Elsa Lopez-Alonso, Benjamin Floran-Garduño, Jose Bernardo Romano-Camach. Role of 5-HT1A and 5-HT1B receptors in the hypophagic effect of 5-HT on the structure of feeding behavior. Medical science monitor : international medical journal of experimental and clinical research. vol 11. issue 3. 2005-07-11. PMID:15735557. |
in order to reveal the involvement of 5-ht1a and 5-ht1b receptors in the paraventricular nucleus of the hypothalamus (pvn) on serotonin-induced hypophagia, we examined the effects of intra-pvn injections of serotonin in way 100635 or sb 216641-pretreated rats on the structure of feeding behavior. |
2005-07-11 |
2023-08-12 |
rat |
| Zoë A Hughes, Kathryn R Starr, Christopher J Langmead, Matthew Hill, Gerd D Bartoszyk, James J Hagan, Derek N Middlemiss, Lee A Dawso. Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone. European journal of pharmacology. vol 510. issue 1-2. 2005-06-28. PMID:15740724. |
vilazodone has been reported to be an inhibitor of 5-hydoxytryptamine (5-ht) reuptake and a partial agonist at 5-ht1a receptors. |
2005-06-28 |
2023-08-12 |
rat |
| Zoë A Hughes, Kathryn R Starr, Christopher J Langmead, Matthew Hill, Gerd D Bartoszyk, James J Hagan, Derek N Middlemiss, Lee A Dawso. Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone. European journal of pharmacology. vol 510. issue 1-2. 2005-06-28. PMID:15740724. |
in summary, vilazodone behaved as a high efficacy partial agonist at the rat hippocampal 5-ht1a receptors in vitro and occupied 5-ht transporters in vivo. |
2005-06-28 |
2023-08-12 |
rat |
| Deborah A Evrard, Ping Zhou, Soo Y Yi, Dahui Zhou, Deborah L Smith, Kelly M Sullivan, Geoffrey A Hornby, Lee E Schechter, Terrance H Andree, Richard E Mewsha. Studies towards the next generation of antidepressants. Part 4: derivatives of 4-(5-fluoro-1H-indol-3-yl)cyclohexylamine with affinity for the serotonin transporter and the 5-HT1A receptor. Bioorganic & medicinal chemistry letters. vol 15. issue 4. 2005-06-15. PMID:15686885. |
part 4: derivatives of 4-(5-fluoro-1h-indol-3-yl)cyclohexylamine with affinity for the serotonin transporter and the 5-ht1a receptor. |
2005-06-15 |
2023-08-12 |
Not clear |
| Nina K Popova, Vladimir S Naumenko, Irena Z Plyusnina, Alexander V Kuliko. Reduction in 5-HT1A receptor density, 5-HT1A mRNA expression, and functional correlates for 5-HT1A receptors in genetically defined aggressive rats. Journal of neuroscience research. vol 80. issue 2. 2005-06-02. PMID:15765530. |
the present experiments tested the hypothesis that one of the critical mechanisms underlying genetically defined aggressiveness involves brain serotonin 5-ht1a receptors. |
2005-06-02 |
2023-08-12 |
rat |
| Robert J Carey, Gail DePalma, Ernest Damianopoulos, Arielle Shanahan, Christian P Müller, Joseph P Husto. Evidence that the 5-HT1A autoreceptor is an important pharmacological target for the modulation of cocaine behavioral stimulant effects. Brain research. vol 1034. issue 1-2. 2005-05-26. PMID:15713268. |
the psychostimulant effects of cocaine critically depend on the serotonergic (5-ht) system, of which the 5-ht1a receptor is an essential component. |
2005-05-26 |
2023-08-12 |
rat |