Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Kaori Tachibana, Machiko Matsumoto, Hiroko Togashi, Taku Kojima, Yuji Morimoto, Osamu Kemmotsu, Mitsuhiro Yoshiok. Milnacipran, a serotonin and noradrenaline reuptake inhibitor, suppresses long-term potentiation in the rat hippocampal CA1 field via 5-HT1A receptors and alpha 1-adrenoceptors. Neuroscience letters. vol 357. issue 2. 2004-05-13. PMID:15036582. |
milnacipran, a serotonin and noradrenaline reuptake inhibitor, suppresses long-term potentiation in the rat hippocampal ca1 field via 5-ht1a receptors and alpha 1-adrenoceptors. |
2004-05-13 |
2023-08-12 |
rat |
Jordi Serrats, Francesc Artigas, Guadalupe Mengod, Roser Corté. An autoradiographic study of the influence of pindolol upon [35S]GTPgammaS binding in rat, guinea pig and human brain. The international journal of neuropsychopharmacology. vol 7. issue 1. 2004-05-07. PMID:14720318. |
the accelerating effect of (+/-)pindolol is thought to derive from its blockade of the ssri-induced, 5-ht1a autoreceptor-mediated inhibition of serotonergic cell firing and 5-ht release. |
2004-05-07 |
2023-08-12 |
human |
Jordi Serrats, Francesc Artigas, Guadalupe Mengod, Roser Corté. An autoradiographic study of the influence of pindolol upon [35S]GTPgammaS binding in rat, guinea pig and human brain. The international journal of neuropsychopharmacology. vol 7. issue 1. 2004-05-07. PMID:14720318. |
in these regions, enriched in 5-ht1a receptors, (+/-)pindolol antagonized the stimulation of [35s]gtpgammas binding induced by 5-ht in a concentration-dependent manner. |
2004-05-07 |
2023-08-12 |
human |
Justin E Aldridge, Frederic J Seidler, Theodore A Slotki. Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling. Environmental health perspectives. vol 112. issue 2. 2004-05-06. PMID:14754568. |
with exposure on gd9-12, cpf elicited global elevations in 5ht1a and 5ht2 receptors and in the 5ht presynaptic transporter. |
2004-05-06 |
2023-08-12 |
Not clear |
Karl-Erik Andersson, Rikard Pehrso. CNS involvement in overactive bladder: pathophysiology and opportunities for pharmacological intervention. Drugs. vol 63. issue 23. 2004-04-29. PMID:14636079. |
with drugs interfering with gaba mechanisms, serotonin 5-ht1a receptors, mu-opioid receptors and alpha-adrenoreceptors. |
2004-04-29 |
2023-08-12 |
Not clear |
Analía Bortolozzi, Mercè Amargós-Bosch, Miklos Toth, Francesc Artigas, Albert Adel. In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice. Journal of neurochemistry. vol 88. issue 6. 2004-04-15. PMID:15009637. |
in vivo efflux of serotonin in the dorsal raphe nucleus of 5-ht1a receptor knockout mice. |
2004-04-15 |
2023-08-12 |
mouse |
Analía Bortolozzi, Mercè Amargós-Bosch, Miklos Toth, Francesc Artigas, Albert Adel. In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice. Journal of neurochemistry. vol 88. issue 6. 2004-04-15. PMID:15009637. |
in the dorsal raphe nucleus (dr), extracellular serotonin (5-ht) regulates serotonergic transmission through 5-ht1a autoreceptors. |
2004-04-15 |
2023-08-12 |
mouse |
Analía Bortolozzi, Mercè Amargós-Bosch, Miklos Toth, Francesc Artigas, Albert Adel. In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice. Journal of neurochemistry. vol 88. issue 6. 2004-04-15. PMID:15009637. |
in this work we used in vivo microdialysis to examine the effects of stressful and pharmacological challenges on dr 5-ht efflux in 5-ht1a receptor knockout (5-ht1a-/-) mice and their wild-type counterparts (5-ht1a+/+). |
2004-04-15 |
2023-08-12 |
mouse |
Analía Bortolozzi, Mercè Amargós-Bosch, Miklos Toth, Francesc Artigas, Albert Adel. In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice. Journal of neurochemistry. vol 88. issue 6. 2004-04-15. PMID:15009637. |
baseline 5-ht concentrations did not differ between both lines of mice, which is consistent with a lack of tonic control of 5-ht1a autoreceptors on dr 5-ht release. |
2004-04-15 |
2023-08-12 |
mouse |
Analía Bortolozzi, Mercè Amargós-Bosch, Miklos Toth, Francesc Artigas, Albert Adel. In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice. Journal of neurochemistry. vol 88. issue 6. 2004-04-15. PMID:15009637. |
the increased responsiveness of the extracellular 5-ht in the dr of 5-ht1a receptor knockout mice reflects a lack of the autoinhibitory control exerted by 5-ht1a autoreceptors. |
2004-04-15 |
2023-08-12 |
mouse |
Mounira Banasr, Micheline Hery, Richard Printemps, Annie Daszut. Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 3. 2004-04-14. PMID:14872203. |
furthermore, both acute and chronic administration of selective 5-ht1a and 5-ht2c receptor agonists produce consistent increases in the number of newly formed neurons in the dg and/or olfactory bulb, underscoring the beneficial effects of 5-ht on adult neurogenesis. |
2004-04-14 |
2023-08-12 |
Not clear |
Prakasham Rumajogee, Daniel Vergé, Naïma Hanoun, Marie-Jeanne Brisorgueil, René Hen, Klaus-Peter Lesch, Michel Hamon, Marie-Christine Mique. Adaption of the serotoninergic neuronal phenotype in the absence of 5-HT autoreceptors or the 5-HT transporter: involvement of BDNF and cAMP. The European journal of neuroscience. vol 19. issue 4. 2004-04-14. PMID:15009141. |
serotonin 5-ht1a and 5-ht1b receptors and the 5-ht transporter are key regulators of the serotoninergic neuronal phenotype. |
2004-04-14 |
2023-08-12 |
mouse |
Prakasham Rumajogee, Daniel Vergé, Naïma Hanoun, Marie-Jeanne Brisorgueil, René Hen, Klaus-Peter Lesch, Michel Hamon, Marie-Christine Mique. Adaption of the serotoninergic neuronal phenotype in the absence of 5-HT autoreceptors or the 5-HT transporter: involvement of BDNF and cAMP. The European journal of neuroscience. vol 19. issue 4. 2004-04-14. PMID:15009141. |
these findings show that the up-regulatory mechanisms triggered by bdnf on serotoninergic neuronal number and neurite extension are different and that the latter are partially linked to 5-ht, probably through 5-ht1a autoreceptors. |
2004-04-14 |
2023-08-12 |
mouse |
Prakasham Rumajogee, Daniel Vergé, Naïma Hanoun, Marie-Jeanne Brisorgueil, René Hen, Klaus-Peter Lesch, Michel Hamon, Marie-Christine Mique. Adaption of the serotoninergic neuronal phenotype in the absence of 5-HT autoreceptors or the 5-HT transporter: involvement of BDNF and cAMP. The European journal of neuroscience. vol 19. issue 4. 2004-04-14. PMID:15009141. |
together, these data suggest that serotonin autoreceptors, mainly 5-ht1a but also 5-ht1b, may be responsible for a tonic auto-inhibitory effect of 5-ht itself on the serotoninergic neuronal phenotype during embryonic development, particularly marked in the absence of the 5-ht transporter. |
2004-04-14 |
2023-08-12 |
mouse |
Rui Tao, Meghana Karnik, Zhiyuan Ma, Sidney B Auerbac. Effect of fentanyl on 5-HT efflux involves both opioid and 5-HT1A receptors. British journal of pharmacology. vol 139. issue 8. 2004-04-12. PMID:12922937. |
effect of fentanyl on 5-ht efflux involves both opioid and 5-ht1a receptors. |
2004-04-12 |
2023-08-12 |
rat |
Xaliproden: SR 57746, SR 57746A, xaliproden hydrochloride, xaliprodene. Drugs in R&D. vol 4. issue 6. 2004-04-12. PMID:14584974. |
xaliproden [sr 57746a, xaliprodene; xaprila] is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-ht1a receptor agonist. |
2004-04-12 |
2023-08-12 |
Not clear |
Mayumi Kondoh, Takashi Shiga, Nobuo Okad. Regulation of dendrite formation of Purkinje cells by serotonin through serotonin1A and serotonin2A receptors in culture. Neuroscience research. vol 48. issue 1. 2004-04-12. PMID:14687886. |
the present study suggested that the dendrite formation of purkinje cells is promoted by 5-ht through 5-ht1a receptors, but inhibited by 5-ht through 5-ht2a receptors. |
2004-04-12 |
2023-08-12 |
rat |
Mercè Amargós-Bosch, Analía Bortolozzi, M Victoria Puig, Jordi Serrats, Albert Adell, Pau Celada, Miklos Toth, Guadalupe Mengod, Francesc Artiga. Co-expression and in vivo interaction of serotonin1A and serotonin2A receptors in pyramidal neurons of prefrontal cortex. Cerebral cortex (New York, N.Y. : 1991). vol 14. issue 3. 2004-04-09. PMID:14754868. |
opposite responses in the same pyramidal neuron could be evoked by stimulating the raphe nuclei at different coordinates, suggesting a precise connectivity between 5-ht neuronal subgroups and 5-ht1a and 5-ht2a receptors in pyramidal neurons. |
2004-04-09 |
2023-08-12 |
mouse |
Mercè Amargós-Bosch, Analía Bortolozzi, M Victoria Puig, Jordi Serrats, Albert Adell, Pau Celada, Miklos Toth, Guadalupe Mengod, Francesc Artiga. Co-expression and in vivo interaction of serotonin1A and serotonin2A receptors in pyramidal neurons of prefrontal cortex. Cerebral cortex (New York, N.Y. : 1991). vol 14. issue 3. 2004-04-09. PMID:14754868. |
microdialysis experiments showed that the increase in local 5-ht release evoked by the activation of 5-ht2a receptors in mpfc by doi (5-ht2a/2c receptor agonist) was reversed by co-perfusion of 5-ht1a agonists. |
2004-04-09 |
2023-08-12 |
mouse |
Antonios Dougalis, George Lees, C Robin Ganelli. The sleep inducing brain lipid cis-oleamide (cOA) does not modulate serotonergic transmission in the CA1 pyramidal neurons of the hippocampus in vitro. Neuropharmacology. vol 46. issue 1. 2004-04-05. PMID:14654098. |
in summary, cis-oleamide failed to modulate metabotropic responses to exogenous 5-ht in this microelectrode study at concentrations well in excess of those reported to modulate 5-ht1a and 5-ht2a/c systems in earlier studies. |
2004-04-05 |
2023-08-12 |
rat |