All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
Stéphanie Caillé, Luis Stinus, Emilio F Espejo, Philippe De Deurwaerdère, Umberto Spampinato, George F Koo. Inhibition of 5-HT neurotransmission increases clonidine protective effects on naloxone-induced conditioned place aversion in morphine-dependent rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 2. 2003-04-21. PMID:12589380. an acute serotonin (5-ht) inhibition induced by the specific stimulation of 5-ht1a autoreceptors (8-ohdpat 5-100 microg/kg), on naloxone-induced conditioned place aversion in morphine-dependent rats. 2003-04-21 2023-08-12 rat
Lalitha Madhavan, William J Freed, Vellareddy Anantharam, Anumantha G Kanthasam. 5-hydroxytryptamine 1A receptor activation protects against N-methyl-D-aspartate-induced apoptotic cell death in striatal and mesencephalic cultures. The Journal of pharmacology and experimental therapeutics. vol 304. issue 3. 2003-04-21. PMID:12604665. in the present study, we investigated whether stimulation of the 5-hydroxytryptamine 1a (5-ht1a) receptor attenuates n-methyl-d-aspartate- (nmda) and 1-methyl-4-phenylpyridinium (mpp(+))-induced apoptotic cell death in cell culture models. 2003-04-21 2023-08-12 rat
E M Cassidy, E Tomkins, T Dinan, O Hardiman, V O'Kean. Central 5-HT receptor hypersensitivity in migraine without aura. Cephalalgia : an international journal of headache. vol 23. issue 1. 2003-04-17. PMID:12534577. this is of relevance given the role of the 5-ht1a receptor in controlling raphe 5-ht tone and in the possible association between migraine and anxiety and depression. 2003-04-17 2023-08-12 human
Jari A Larm, Pei-Juan Shen, Andrew L Gundlac. Differential galanin receptor-1 and galanin expression by 5-HT neurons in dorsal raphé nucleus of rat and mouse: evidence for species-dependent modulation of serotonin transmission. The European journal of neuroscience. vol 17. issue 3. 2003-04-10. PMID:12581166. 5-ht neuron activity in the drn is primarily regulated via 5-ht1a autoreceptors, via inhibition of adenylate cyclase and activation of inward-rectifying k+ channels. 2003-04-10 2023-08-12 mouse
Daisuke Mochizuki, Tadami Hokonohara, Koh Kawasaki, Naomasa Mik. Repeated administration of milnacipran induces rapid desensitization of somatodendritic 5-HT1A autoreceptors but not postsynaptic 5-HT1A receptors. Journal of psychopharmacology (Oxford, England). vol 16. issue 3. 2003-04-07. PMID:12236634. the effects of the repeated administration of milnacipran, a serotonin (5-ht)-noradrenaline reuptake inhibitor (snri), on the functional status of somatodendritic 5-ht1a receptors, and postsynaptic 5-ht1a receptors were explored using electrophysiological approaches in rats. 2003-04-07 2023-08-12 rat
Daisuke Mochizuki, Tadami Hokonohara, Koh Kawasaki, Naomasa Mik. Repeated administration of milnacipran induces rapid desensitization of somatodendritic 5-HT1A autoreceptors but not postsynaptic 5-HT1A receptors. Journal of psychopharmacology (Oxford, England). vol 16. issue 3. 2003-04-07. PMID:12236634. in-vitro electrophysiological recordings in the dorsal raphe nucleus showed that 5-ht inhibited the firing of serotonergic neurones, and the selective 5-ht1a receptor antagonist, n-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-n-(2-pyridinyl) cyclohexane carboxamide (way 100635), reversed the inhibitory effect of 5-ht. 2003-04-07 2023-08-12 rat
b' Ar\\xc3\\xa1nzazu Roca-Vinardell, Antonio Ortega-Alvaro, Juan Gibert-Rahola, Juan A Mic\\xc3\\xb. The role of 5-HT1A/B autoreceptors in the antinociceptive effect of systemic administration of acetaminophen. Anesthesiology. vol 98. issue 3. 2003-03-27. PMID:12606921.' the serotonin activity in the brainstem is primarily under the control of 5-ht1a somatodendritic receptors, although some data also suggest the involvement of 5-ht1b receptors. 2003-03-27 2023-08-12 mouse
T S Sperry, C K Thompson, J C Wingfiel. Effects of acute treatment with 8-OH-DPAT and fluoxetine on aggressive behaviour in male song sparrows (Melospiza melodia morphna). Journal of neuroendocrinology. vol 15. issue 2. 2003-03-26. PMID:12535157. fluoxetine is a selective serotonin reuptake inhibitor of the neuronal reuptake pump increasing synaptic concentrations of serotonin, and 8-oh-dpat is a specific serotonin (5-ht1a) receptor agonist. 2003-03-26 2023-08-12 Not clear
N H Bhanji, H C Margolese, M Saint-Laurent, G Chouinar. Dysphoric mania induced by high-dose mirtazapine: a case for 'norepinephrine syndrome'? International clinical psychopharmacology. vol 17. issue 6. 2003-02-25. PMID:12409687. histamine h2 receptors are also antagonized, as are postsynaptic serotonin 5-ht2 and 5-ht3 receptors, leading to serotonergic activity primarily via 5-ht1a receptors. 2003-02-25 2023-08-12 human
Nicholas J Delva, Deborah L Brooks, Michael Franklin, Khalid al-Said, Emily R Hawken, Zul Merali, J Stuart Lawson, Arun V Ravindra. Effects of short-term administration of valproate on serotonin-1A and dopamine receptor function in healthy human subjects. Journal of psychiatry & neuroscience : JPN. vol 27. issue 6. 2003-02-11. PMID:12491576. to examine the effects of short-term valproate treatment on human brain serotonin and dopamine function by means of challenge tests with ipsapirone, a partial agonist at 5-ht1a receptors, and apomorphine, a dopamine receptor agonist. 2003-02-11 2023-08-12 human
Luca Santarelli, Gabriella Gobbi, Pierre Blier, René He. Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1). The Journal of clinical psychiatry. vol 63 Suppl 11. 2003-02-11. PMID:12562138. in parallel with these behavioral effects, physiologic changes, such as an increased firing rate of 5-hydroxytryptamine (5-ht) neurons in the dorsal raphe nuclei and a desensitization of presynaptic 5-ht1a inhibitory autoreceptors, were observed. 2003-02-11 2023-08-12 mouse
Theresa Schweizer, Anja Birthelmer, Hélène Jeltsch, Jean-Christophe Cassel, Rolf Jackisc. Raphé grafts and 3,4-diaminopyridine-evoked overflow of serotonin in the rat hippocampus after 5,7-dihydroxytryptamine lesions: evidence for 5-HT1A autoreceptors. Neuroreport. vol 13. issue 15. 2003-02-07. PMID:12395082. raphé grafts and 3,4-diaminopyridine-evoked overflow of serotonin in the rat hippocampus after 5,7-dihydroxytryptamine lesions: evidence for 5-ht1a autoreceptors. 2003-02-07 2023-08-12 rat
Ramin V Parsey, Maria A Oquendo, Norman R Simpson, R Todd Ogden, Ronald Van Heertum, Victoria Arango, J John Man. Effects of sex, age, and aggressive traits in man on brain serotonin 5-HT1A receptor binding potential measured by PET using [C-11]WAY-100635. Brain research. vol 954. issue 2. 2003-01-28. PMID:12414100. effects of sex, age, and aggressive traits in man on brain serotonin 5-ht1a receptor binding potential measured by pet using [c-11]way-100635. 2003-01-28 2023-08-12 Not clear
Siegfried Kasper, Johannes Tauscher, Matthäus Willeit, Mara Stamenkovic, Alexander Neumeister, Bernd Küfferle, Christian Barnas, Jürgen Stastny, Nicole Praschak-Rieder, Lukas Pezawas, Martina de Zwaan, Sylvia Quiner, Walter Pirker, Susanne Asenbaum, Ivo Podreka, Thomas Brück. Receptor and transporter imaging studies in schizophrenia, depression, bulimia and Tourette's disorder--implications for psychopharmacology. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 3. issue 3. 2003-01-23. PMID:12478878. striatal d2 and 5-ht1a receptors were studied in schizophrenia and 5-ht transporters (5-htt) in depression and bulimia. 2003-01-23 2023-08-12 human
Prakasham Rumajogee, Alexandra Madeira, Daniel Vergé, Michel Hamon, Marie-Christine Mique. Up-regulation of the neuronal serotoninergic phenotype in vitro: BDNF and cAMP share Trk B-dependent mechanisms. Journal of neurochemistry. vol 83. issue 6. 2003-01-16. PMID:12472905. these changes were associated with marked increases in the levels of mrnas encoding the serotonin transporter, the 5-ht1a and 5-ht1b receptors and the bdnf receptor tyrosine kinase b (trkb). 2003-01-16 2023-08-12 rat
K Pruus, R Rudisaar, A Vaarmann, V Matto, L Allikmet. 1-(1-naphthyl)-piperazine, a mixed 5-HT1A and 5-HT2A/2C receptor ligand, elicits an anxiolytic-like effect in the open-field test without changes in 5-HT metabolism. Methods and findings in experimental and clinical pharmacology. vol 24. issue 3. 2003-01-10. PMID:12087877. 1-(1-naphthyl)-piperazine, a mixed 5-ht1a and 5-ht2a/2c receptor ligand, elicits an anxiolytic-like effect in the open-field test without changes in 5-ht metabolism. 2003-01-10 2023-08-12 rat
Y Ozawa, S Takashim. Developmental neurotransmitter pathology in the brainstem of sudden infant death syndrome: a review and sleep position. Forensic science international. vol 130 Suppl. 2003-01-02. PMID:12350301. in sids infants, there are an increase of glial fibrillary acidic protein (gfap)-positive astrocytes in the brainstem, an increase of substance p (sp) in the medulla and pons, a decrease of tyrosine hydroxylase (th)-positive catecholaminergic neurons in the ventrolateral medulla (vlm), and vagal nuclei in the medulla oblongata and basal ganglia, a decrease of tryptophan hydroxylase (trh)-positive serotonergic neurons in the periaqueductal gray matter (pag), and decreases of 5-hydroxytryptamine 1a (5-ht1a) and 5-ht2a receptor immunoreactivities in the vlm and vagal nuclei in the medulla oblongata. 2003-01-02 2023-08-12 Not clear
Mónica B Frungieri, Karina Zitta, Omar P Pignataro, Silvia I Gonzalez-Calvar, Ricardo S Calandr. Interactions between testicular serotoninergic, catecholaminergic, and corticotropin-releasing hormone systems modulating cAMP and testosterone production in the golden hamster. Neuroendocrinology. vol 76. issue 1. 2002-12-20. PMID:12097815. by using several agonists and antagonists of 5-ht receptors, we characterized 5-ht1a and 5-ht2a receptor subtypes involved in the inhibitory action of this neurotransmitter on human chorionic gonadotropin stimulated cyclic adenosine monophosphate and testosterone production. 2002-12-20 2023-08-12 human
Yuki Iwahori, Yuji Ikegaya, Norio Matsuk. Hyperpolarization-activated current I(h) in nucleus of solitary tract neurons: regional difference in serotonergic modulation. Japanese journal of pharmacology. vol 88. issue 4. 2002-12-12. PMID:12046990. the effect of 5-ht was blocked by nan-190, a 5-ht1a receptor antagonist. 2002-12-12 2023-08-12 Not clear
M Bourin, D J P David, P Jolliet, A Gardie. [Mechanism of action of antidepressants and therapeutic perspectives]. Therapie. vol 57. issue 4. 2002-12-10. PMID:12422559. behavioural, electrophysiological and microdialysis studies have shown that serotonin (5-ht) receptors, mainly 5-ht1a, 5-ht1b and 5-ht2c sub-types, exert a key role in modulating antidepressant activity. 2002-12-10 2023-08-12 Not clear