All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
M N Subhash, B N Srinivas, K Y Vinod, S Jagadees. Modulation of 5-HT1A receptor mediated response by fluoxetine in rat brain. Journal of neural transmission (Vienna, Austria : 1996). vol 107. issue 3. 2000-08-02. PMID:10821446. the increase in 5-ht stimulated ac activity in cortex may be due to the significant downregulation of 5-ht1a sites in cortex after fluoxetine exposure as these sites are negatively coupled to ac. 2000-08-02 2023-08-12 rat
M N Subhash, B N Srinivas, K Y Vinod, S Jagadees. Modulation of 5-HT1A receptor mediated response by fluoxetine in rat brain. Journal of neural transmission (Vienna, Austria : 1996). vol 107. issue 3. 2000-08-02. PMID:10821446. the observed significant decrease in 5-ht1 sites with concomitant increase in 5-ht stimulated ac activity, after fluoxetine treatment, suggests that fluoxetine, which has high affinity for these sites, acts by modulating the 5-ht1a receptor mediated response in brain. 2000-08-02 2023-08-12 rat
N Haddjeri, P Blie. Effect of neurokinin-I receptor antagonists on the function of 5-HT and noradrenaline neurons. Neuroreport. vol 11. issue 6. 2000-07-17. PMID:10817615. administration of the 5-ht autoreceptor agonist lsd and the 5-ht1a receptor agonist 8-oh-dpat remained unchanged. 2000-07-17 2023-08-12 rat
M Kubera, G Kenis, E Bosmans, S Scharpé, M Mae. Effects of serotonin and serotonergic agonists and antagonists on the production of interferon-gamma and interleukin-10. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 1. 2000-07-17. PMID:10869889. this study was carried out to examine the effects of 5-ht, p-chlorophenylalanine (pcpa), a 5-ht depleting agent, flesinoxan (a 5-ht1a agonist), m-chlorophenylpiperazine (mcpp; a 5-ht2a/2c agonist), and ritanserin (a 5-ht2a/2c antagonist) on the production rate of interferon-gamma (ifngamma), a proinflammatory cytokine, and il-10 by whole blood stimulated with polyclonal activators. 2000-07-17 2023-08-12 Not clear
J M Monti, D Mont. Role of dorsal raphe nucleus serotonin 5-HT1A receptor in the regulation of REM sleep. Life sciences. vol 66. issue 21. 2000-06-23. PMID:10823340. role of dorsal raphe nucleus serotonin 5-ht1a receptor in the regulation of rem sleep. 2000-06-23 2023-08-12 Not clear
L J Dreshfield-Ahmad, D C Thompson, J M Schaus, D T Won. Enhancement in extracellular serotonin levels by 5-hydroxytryptophan loading after administration of WAY 100635 and fluoxetine. Life sciences. vol 66. issue 21. 2000-06-23. PMID:10823343. in the present series of experiments, we examined the effects of precursor (5-htp) loading on extracellular hypothalamic 5-ht after administration of fluoxetine alone or in combination with way 100635, a selective 5-ht1a antagonist. 2000-06-23 2023-08-12 Not clear
L J Dreshfield-Ahmad, D C Thompson, J M Schaus, D T Won. Enhancement in extracellular serotonin levels by 5-hydroxytryptophan loading after administration of WAY 100635 and fluoxetine. Life sciences. vol 66. issue 21. 2000-06-23. PMID:10823343. these results suggest that combining blockade of 5-ht1a autoreceptors with 5-ht uptake inhibition results in a synergistic increase in synthesis and release of 5-ht when precursor is administered. 2000-06-23 2023-08-12 Not clear
J A Sacristán, I Gilaberte, B Boto, D P Buesching, R L Obenchain, M Demitrack, V Pérez Sola, E Alvarez, F Artiga. Cost-effectiveness of fluoxetine plus pindolol in patients with major depressive disorder: results from a randomized, double-blind clinical trial. International clinical psychopharmacology. vol 15. issue 2. 2000-06-16. PMID:10759342. some preliminary studies have suggested that the beta-adrenoceptor 5-ht1a antagonist pindolol (pin) could increase the effect of selective serotonin reuptake inhibitors (ssris). 2000-06-16 2023-08-12 Not clear
A V Kulikov, R Jeanningr. [Effect of hypothyroidism on 5-HT1A-, 5-HT2A-receptors and serotonin transporter in the rat brain]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 86. issue 3. 2000-05-31. PMID:10808528. effects of thyroid hormone deficiency on 5-ht1a receptors, 5-ht2a receptors and serotonin transporter in the brain were studied in thyroidectomised wistar rats receiving an iodine-free diet and receiving 15 micrograms/kg of thyroxine for 21 days. 2000-05-31 2023-08-12 rat
A V Kulikov, R Jeanningr. [Effect of hypothyroidism on 5-HT1A-, 5-HT2A-receptors and serotonin transporter in the rat brain]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 86. issue 3. 2000-05-31. PMID:10808528. binding of 3h-8-oh-dpat to 5-ht1a receptors and 3h-cytalopram to serotonin transporter were unchanged in hypothyroid rats as compared to the control. 2000-05-31 2023-08-12 rat
A García-Osta, D Frechilla, J Del Rí. Effect of p-chloroamphetamine on 5-HT1A and 5-HT7 serotonin receptor expression in rat brain. Journal of neurochemistry. vol 74. issue 5. 2000-05-25. PMID:10800921. the aim of this study was to investigate if p-chloroamphetamine (pca), which is neurotoxic to serotonin (5-ht) nerve terminals, was able to induce, like 3,4-methylenedioxymethamphetamine, a region-specific regulation of 5-ht1a receptor mrna expression. 2000-05-25 2023-08-12 rat
R Dall'Olio, R Gaggi, V Bonfante, O Gandolf. The non-competitive NMDA receptor blocker dizocilpine potentiates serotonergic function. Behavioural pharmacology. vol 10. issue 1. 2000-05-18. PMID:10780303. forepaw treading induced in rats by the 5ht1a agonist 8-oh-dpat, and head shakes caused by the administration of the 5ht2a receptor against doi, and by the 5ht precursor (-)5htp, were significantly increased by pretreatment with the non-competitive n-methyl-d-aspartate (nmda) antagonist dizocilpine. 2000-05-18 2023-08-12 rat
A Kulikov, X Moreau, R Jeanningro. Effects of experimental hypothyroidism on 5-HT1A, 5-HT2A receptors, 5-HT uptake sites and tryptophan hydroxylase activity in mature rat brain1. Neuroendocrinology. vol 69. issue 6. 2000-04-11. PMID:10364698. effects of experimental hypothyroidism on 5-ht1a, 5-ht2a receptors, 5-ht uptake sites and tryptophan hydroxylase activity in mature rat brain1. 2000-04-11 2023-08-12 rat
A Kulikov, X Moreau, R Jeanningro. Effects of experimental hypothyroidism on 5-HT1A, 5-HT2A receptors, 5-HT uptake sites and tryptophan hydroxylase activity in mature rat brain1. Neuroendocrinology. vol 69. issue 6. 2000-04-11. PMID:10364698. the study was aimed at investigating the repercussions of deficiency in thyroid function with and without thyroid hormone (th) replacement on the neurochemical entities which underly serotonin (5-ht) neutrotransmission, namely 5-ht1a, 5-ht2a receptors, 5-ht transporter and tryptophan hydroxylase (tph) in the mature brain. 2000-04-11 2023-08-12 rat
A Kulikov, X Moreau, R Jeanningro. Effects of experimental hypothyroidism on 5-HT1A, 5-HT2A receptors, 5-HT uptake sites and tryptophan hydroxylase activity in mature rat brain1. Neuroendocrinology. vol 69. issue 6. 2000-04-11. PMID:10364698. neither hypothyroidism nor an excess in serum th levels affected 3h-8-oh-dpat binding to 5-ht1a receptors, 3h-citalopram binding to 5-ht transporter and tph activity in various brain structures indicating that, in the mature brain, the presynaptic entities of 5-ht neurotransmission are resistant to large variations in th levels. 2000-04-11 2023-08-12 rat
I D Hentall, P J Kurle, T R Whit. Correlations between serotonin level and single-cell firing in the rat's nucleus raphe magnus. Neuroscience. vol 95. issue 4. 2000-03-21. PMID:10682715. the released serotonin could contribute to the inhibition of off(m) cells and excitation of on(m) cells by noxious stimulation, since inhibitory 5-ht1a receptors and excitatory 5-ht2 receptors, respectively, have previously been shown to dominate their serotonergic responses. 2000-03-21 2023-08-12 rat
R C Silva, M L Brandã. Acute and chronic effects of gepirone and fluoxetine in rats tested in the elevated plus-maze: an ethological analysis. Pharmacology, biochemistry, and behavior. vol 65. issue 2. 2000-03-14. PMID:10672971. in the present study we provided an ethopharmacological analysis (in addition to conventional measures) of the behavior of rats in the elevated plus-maze with transparent walls after acute and chronic treatments with gepirone, an agonist of 5-ht1a receptors, and fluoxetine, a selective inhibitor of serotonin reuptake. 2000-03-14 2023-08-12 human
L Palego, A Giromella, D Marazziti, G Giannaccini, F Borsini, F Bigazzi, A G Naccarato, A Lucacchini, G B Cassano, M R Mazzon. Lack of stereoselectivity of 8-hydroxy-2(di-N-propylamino)tetralin-mediated inhibition of forskolin-stimulated adenylyl cyclase activity in human pre- and post-synaptic brain regions. Neurochemistry international. vol 36. issue 3. 2000-03-02. PMID:10676857. the stereoselectivity of the serotonin1a (5-ht1a) receptor compound 8-hydroxy-2(di-n-propylamino)tetralin (8-oh-dpat) on forskolin-stimulated adenylyl cyclase activity was investigated in membranes from human 5-ht pre-synaptic (raphe nuclei) and post-synaptic (hippocampus and prefrontal cortex) regions of autopsy brains. 2000-03-02 2023-08-12 human
A N Rizk, P J Hesket. Antiemetics for cancer chemotherapy-induced nausea and vomiting. A review of agents in development. Drugs in R&D. vol 2. issue 4. 2000-02-28. PMID:10659396. several other serotonin receptors have been targeted including the 5-ht4, 5-ht1a and 5-ht2a receptors. 2000-02-28 2023-08-12 Not clear
S E Marshall, T G Bird, K Hart, K I Wels. Unified approach to the analysis of genetic variation in serotonergic pathways. American journal of medical genetics. vol 88. issue 6. 2000-02-24. PMID:10581480. these genes include tryptophan hydroxylase, tryptophan dioxygenase, monoamine oxidase a, and the serotonin receptors 5ht1a, 5ht1d-alpha, 5ht1d-beta, 5ht2a, 5ht2c, and 5ht5a. 2000-02-24 2023-08-12 Not clear