All Relations between 5-ht receptor 1b and 5-ht receptor 1d

Publication Sentence Publish Date Extraction Date Species
Roshan Chanchlani, Amit Agrawal, Dalwinder Janjua, Shaik Nida Hafs. The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review. Indian pediatrics. 2023-05-20. PMID:37209053. serotonin receptors 5-ht1b and 5-ht1d in the cerebral arteries are activated by the 5-hydroxytryptophan agonists (triptans) to relieve the discomfort associated with migraines. 2023-05-20 2023-08-14 Not clear
Nuh Mehmet Bozkurt, Gokhan Una. Vortioxetine Improved Negative and Cognitive Symptoms of Schizophrenia in Subchronic MK-801 Induced Schizophrenia Model in Rats. Behavioural brain research. 2023-03-01. PMID:36858318. vortioxetine is a new multimodal antidepressant with 5-ht1a agonism, 5-ht1b partial agonism, 5-ht3, 5-ht7, and 5-ht1d antagonism, and serotonin reuptake inhibition. 2023-03-01 2023-08-14 rat
Hayder M Al-Kuraishy, Ali I Al-Gareeb, Athanasios Alexiou, Nobendu Mukerjee, Sadiq Mohammed J Al-Hamash, Thabat J Al-Maiahy, Gaber El-Saber Batih. 5-HT/CGRP pathway and Sumatriptan role in Covid-19. Biotechnology & genetic engineering reviews. 2022-08-31. PMID:36042570. sumatriptan is a pre-synaptic 5-ht (5-ht1d and 5-ht1b) agonist and inhibits the release of cgrp. 2022-08-31 2023-08-14 Not clear
Daniela Adamo, Elena Calabria, Noemi Coppola, Giuseppe Pecoraro, Michele Davide Mignogn. Vortioxetine as a new frontier in the treatment of chronic neuropathic pain: a review and update. Therapeutic advances in psychopharmacology. vol 11. 2021-09-10. PMID:34497709. this drug inhibits the serotonin transporter with a high affinity, antagonises the 5-ht3, 5-ht1d and 5ht7 serotonin receptors, and activates the 5-ht1a and 5-ht1b receptors. 2021-09-10 2023-08-13 Not clear
Anoosha Attaran, Arash Salahinejad, Mohammad Naderi, Adam L Crane, Douglas P Chivers, Som Niyog. Transgenerational effects of selenomethionine on behaviour, social cognition, and the expression of genes in the serotonergic pathway in zebrafish. Environmental pollution (Barking, Essex : 1987). vol 286. 2021-08-25. PMID:33971468. maternal exposure to high levels of se-met also led to dysregulation of the serotonergic system via changes in mrna expression of serotonin receptors, including the 5-ht1a, 5-ht1b, and 5-ht1d subtypes, the serotonin transporter, and monoamine oxidase (mao). 2021-08-25 2023-08-13 human
Fatemeh Gharishvandi, Alireza Abdollahi, Hamed Shafaroodi, Razieh Mohammad Jafari, Parvin Pasalar, Ahmad Reza Dehpou. Involvement of 5-HT1B/1D receptors in the inflammatory response and oxidative stress in intestinal ischemia/reperfusion in rats. European journal of pharmacology. vol 882. 2021-05-13. PMID:32574671. 5-hydroxytryptamine 1b (5-ht1b) and 5-ht1d receptors have anti-inflammatory and neuroprotective effects in different experimental studies. 2021-05-13 2023-08-13 rat
Jane Khalife, Clinton G Lauritsen, John Liang, Syed O Sha. DHE-Induced Peripheral Arterial Vasospasm in Primary Raynaud Phenomenon: Case Report. The Neurohospitalist. vol 9. issue 2. 2020-10-01. PMID:30915191. dihydroergotamine (dhe) is primarily a serotonin 5ht1b and 5ht1d receptor agonist used for acute migraine treatment. 2020-10-01 2023-08-13 Not clear
Anna Rita Zuena, Daniela Maftei, Giovanni Sebastiano Alemà, Francesca Dal Moro, Roberta Lattanzi, Paola Casolini, Ferdinando Nicolett. Multimodal antidepressant vortioxetine causes analgesia in a mouse model of chronic neuropathic pain. Molecular pain. vol 14. 2019-02-20. PMID:30289053. vortioxetine is a multimodal antidepressant that potently antagonizes 5-ht3 serotonin receptors, inhibits the high-affinity serotonin transporter, activates 5-ht1a and 5-ht1b receptors, and antagonizes 5-ht1d and 5-ht7 receptors. 2019-02-20 2023-08-13 mouse
Miriam A Snider, David L Harmon, James L Klot. Pharmacologic assessment of bovine ruminal and mesenteric vascular serotonin receptor populations. Journal of animal science. vol 96. issue 4. 2018-10-09. PMID:29471490. to determine what 5-ht receptors are involved in vasoconstriction of gut vasculature, contractility of ruminal and mesenteric arteries and veins collected from cattle was evaluated in the presence of agonists selective for 5-ht1b (cp 93129), 5-ht1d (l-694, 247), 5-ht2a (tcb-2), 5-ht2b (bw 723c86), 5-ht4 (bimu-8), and 5-ht7 (lp 44) receptors. 2018-10-09 2023-08-13 cattle
b' Eldina Rizvi\\xc4\\x87, Goran Jankovi\\xc4\\x87, Sla\\xc4\\x91ana Kosti\\xc4\\x87-Raja\\xc4\\x8di\\xc4\\x87, Miroslav M Savi\\xc4\\x8. Atypical sympathomimetic drug lerimazoline mediates contractile effects in rat aorta predominantly by 5-HT2A receptors. Bosnian journal of basic medical sciences. vol 17. issue 3. 2018-07-12. PMID:28628756.' we also determined the effect of several antagonists on the contractile response to lerimazoline, including prazosin (α1-adrenoceptor antagonist), rx 821002 and rauwolscine (α2-adrenoceptor antagonists), jp 1302 (α2c-adrenoceptor antagonist), methiothepin (non-selective 5-ht receptor antagonist), sb 224289 (5-ht1b receptor antagonist), brl 15572 (5-ht1d receptor antagonist), and ketanserin (5-ht2a receptor antagonist). 2018-07-12 2023-08-13 rat
Lauren Hatherall, Connie Sánchez, David A Morila. Chronic Vortioxetine Treatment Reduces Exaggerated Expression of Conditioned Fear Memory and Restores Active Coping Behavior in Chronically Stressed Rats. The international journal of neuropsychopharmacology. vol 20. issue 4. 2018-05-18. PMID:27927740. vortioxetine, a novel multimodal antidepressant, is a serotonin transporter inhibitor; 5-ht3, 5-ht7, and 5-ht1d receptor antagonist; 5-ht1b partial agonist; and 5-ht1a agonist. 2018-05-18 2023-08-13 rat
Andrea de Bartolomeis, Andrea Fagiolini, Giuseppe Main. [Vortioxetine in the treatment of major depression]. Rivista di psichiatria. vol 51. issue 6. 2017-11-20. PMID:27996982. vortioxetine is a multi-modal antidepressant that functions both as serotonin transporter (sert) inhibitor and as 5-ht3, 5-ht7 and 5-ht1d receptors antagonist, 5-ht1a receptor agonist and 5-ht1b receptor partial agonist. 2017-11-20 2023-08-13 Not clear
D J David, A M Gardie. [The pharmacological basis of the serotonin system: Application to antidepressant response]. L'Encephale. vol 42. issue 3. 2017-09-20. PMID:27112704. serotonin's homeostasis involves serotoninergic autoreceptor such as 5-ht1a, 5-ht1b, 5-ht1d, the enzymatic degradation of serotonin by monoamine oxidase a (mao-a), and a transporter (serotoninergic transporter [sert]). 2017-09-20 2023-08-13 Not clear
D J David, A M Gardie. [The pharmacological basis of the serotonin system: Application to antidepressant response]. L'Encephale. vol 42. issue 3. 2017-09-20. PMID:27112704. among all the 5-ht receptors, 5-ht1a, 5-ht1b, 5-ht1d, 5-ht2b and 5-ht4 receptors activation would mediate antidepressant effects. 2017-09-20 2023-08-13 Not clear
Laura Orsolini, Carmine Tomasetti, Alessandro Valchera, Felice Iasevoli, Elisabetta Filomena Buonaguro, Federica Vellante, Michele Fornaro, Annastasia Fiengo, Monica Mazza, Roberta Vecchiotti, Giampaolo Perna, Andrea de Bartolomeis, Giovanni Martinotti, Massimo Di Giannantonio, Domenico De Berardi. New advances in the treatment of generalized anxiety disorder: the multimodal antidepressant vortioxetine. Expert review of neurotherapeutics. vol 16. issue 5. 2017-06-27. PMID:27050932. vortioxetine (vrx) is a multimodal antidepressant with a unique mechanism of action, by acting as 5-ht3a, 5-ht1d and 5-ht7 receptor antagonist, partial agonist at the 5-ht1a and 5-ht1b receptors and inhibitor at the 5-ht transporter. 2017-06-27 2023-08-13 Not clear
Dioneia Araldi, Luiz F Ferrari, Jon D Levin. Gi-protein-coupled 5-HT1B/D receptor agonist sumatriptan induces type I hyperalgesic priming. Pain. vol 157. issue 8. 2017-03-13. PMID:27075428. the prolongation of pge2 hyperalgesia induced by sumatriptan was partially prevented by coinjection of antagonists for the 5-ht1b and 5-ht1d, but not 5-ht7, serotonin receptors and completely prevented by coadministration of a combination of the 5-ht1b and 5-ht1d antagonists. 2017-03-13 2023-08-13 rat
Guadalupe C Vidal-Cantú, Mildred Jiménez-Hernández, Héctor I Rocha-González, Carlos M Villalón, Vinicio Granados-Soto, Enriqueta Muñoz-Isla. Role of 5-HT5A and 5-HT1B/1D receptors in the antinociception produced by ergotamine and valerenic acid in the rat formalin test. European journal of pharmacology. vol 781. 2017-03-08. PMID:27068146. the antinociception by intrathecal ergotamine (15nmol) or valerenic acid (1nmol) was partly or completely blocked by intrathecal administration of the antagonists: (i) methiothepin (non-selective 5-ht5a/5b; 0.01-0.1nmol); (ii) sb-699551 (selective 5-ht5a; up to 10nmol); (iii) anti-5-ht5a antibody; (iv) sb-224289 (selective 5-ht1b; 0.1-1nmol); or (v) brl-15572 (selective 5-ht1d; 0.1-1nmol). 2017-03-08 2023-08-13 rat
Gennady N Smagin, Dekun Song, David P Budac, Jessica A Waller, Yan Li, Alan L Pehrson, Connie Sánche. Histamine may contribute to vortioxetine's procognitive effects; possibly through an orexigenic mechanism. Progress in neuro-psychopharmacology & biological psychiatry. vol 68. 2017-01-02. PMID:26945513. vortioxetine is a novel multimodal antidepressant that acts as a serotonin (5-ht)3, 5-ht7, and 5-ht1d receptor antagonist; 5-ht1b receptor partial agonist; 5-ht1a receptor agonist; and 5-ht transporter inhibitor in vitro. 2017-01-02 2023-08-13 rat
J A García-Pedraza, M García, M L Martín, A Rodríguez-Barbero, A Morá. 5-HT2 receptor blockade exhibits 5-HT vasodilator effects via nitric oxide, prostacyclin and ATP-sensitive potassium channels in rat renal vasculature. Vascular pharmacology. vol 79. 2016-12-13. PMID:26586311. agonists 5-ct (5-ht1/7), cgs-12066b (5-ht1b), l-694,247 (5-ht1d) or as-19 (5-ht7) mimicked renal 5-ht vasodilator effect. 2016-12-13 2023-08-13 rat
J A García-Pedraza, M García, M L Martín, A Rodríguez-Barbero, A Morá. 5-HT2 receptor blockade exhibits 5-HT vasodilator effects via nitric oxide, prostacyclin and ATP-sensitive potassium channels in rat renal vasculature. Vascular pharmacology. vol 79. 2016-12-13. PMID:26586311. our data suggest that 5-ht exerts renal vasodilator effect in the in situ autoperfused sarpogrelate-treated rat kidney, mediated by 5-ht1d, 5-ht1b and 5-ht7 receptors, involving cyclooxygenase-derived prostacyclin, nitric oxide synthesis/release and atp-sensitive k+ channels, respectively. 2016-12-13 2023-08-13 rat