| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Agata Zięba, Damian Bartuzi, Piotr Stępnicki, Dariusz Matosiuk, Tomasz M Wróbel, Tuomo Laitinen, Marián Castro, Agnieszka Anna Kaczo. Discovery and in vitro Evaluation of Novel Serotonin 5-HT2A Receptor Ligands Identified Through Virtual Screening. ChemMedChem. 2024-04-15. PMID:38619283. |
discovery and in vitro evaluation of novel serotonin 5-ht2a receptor ligands identified through virtual screening. |
2024-04-15 |
2024-04-17 |
Not clear |
| Maram B Alhawarri, Suleiman Olima. Potential Serotonin 5-HT2A Receptor Agonist of Psychoactive Components of Silene undulata Aiton: LC-MS/MS, ADMET, and Molecular Docking Studies. Current pharmaceutical biotechnology. 2024-04-01. PMID:38561607. |
potential serotonin 5-ht2a receptor agonist of psychoactive components of silene undulata aiton: lc-ms/ms, admet, and molecular docking studies. |
2024-04-01 |
2024-04-04 |
Not clear |
| Giuseppe Bruschetta, Gabriella Zanghì, Renato Paolo Giunta, Alida Maria Ferlazzo, Katiuska Satué, Angela D'Ascola, Esterina Fazi. Short Road Transport and Slaughter Stress Affects the Expression Profile of Serotonin Receptors, Adrenocortical, and Hematochemical Responses in Horses. Veterinary sciences. vol 11. issue 3. 2024-03-27. PMID:38535847. |
the aim of this research was to investigate the effect of horse transportation and slaughter stress on plasma serotonin's concentration and the expression levels of the related 5-ht1b and 5-ht2a receptors in pbmcs. |
2024-03-27 |
2024-03-29 |
Not clear |
| Małgorzata Łupina, Agnieszka Wąsik, Irena Baranowska-Bosiacka, Maciej Tarnowski, Tymoteusz Słowik, Piotr Listos, Jolanta Kotlińska, Danuta Kosik-Bogacka, Izabela Gutowska, Joanna Listo. Acute and Chronic Exposure to Linagliptin, a Selective Inhibitor of Dipeptidyl Peptidase-4 (DPP-4), Has an Effect on Dopamine, Serotonin and Noradrenaline Level in the Striatum and Hippocampus of Rats. International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38474255. |
acute linagliptin exposure increases the serotonin level in both areas, while after chronic linagliptin administration a tendency for the mrna expression of serotoninergic receptors (5-ht1a and 5-ht2a) to increase was observed. |
2024-03-13 |
2024-03-15 |
rat |
| Yu Dai, Chenchen Zhang, Lingrui Zhang, Chao Wen, Hongya Li, Tianmin Zh. Genetic polymorphism in HTR2A rs6313 is associated with internet addiction disorder. Frontiers in psychiatry. vol 15. 2024-02-29. PMID:38419907. |
in this study, we aimed to investigate the association between iad and rs6313 (t102c) polymorphism in the serotonin 2a receptor (5-ht2a) gene, (htr2a). |
2024-02-29 |
2024-03-02 |
Not clear |
| Samantha Alvarez-Herrera, Mauricio Rosel Vales, Gilberto Pérez-Sánchez, Enrique Becerril-Villanueva, Yvonne Flores-Medina, José Luis Maldonado-García, Ricardo Saracco-Alvarez, Raúl Escamilla, Lenin Pavó. Risperidone Decreases Expression of Serotonin Receptor-2A (5-HT2A) and Serotonin Transporter (SERT) but Not Dopamine Receptors and Dopamine Transporter (DAT) in PBMCs from Patients with Schizophrenia. Pharmaceuticals (Basel, Switzerland). vol 17. issue 2. 2024-02-24. PMID:38399382. |
risperidone decreases expression of serotonin receptor-2a (5-ht2a) and serotonin transporter (sert) but not dopamine receptors and dopamine transporter (dat) in pbmcs from patients with schizophrenia. |
2024-02-24 |
2024-02-26 |
Not clear |
| Roberto Ogelman, Luis E Gomez Wulschner, Victoria M Hoelscher, In-Wook Hwang, Victoria N Chang, Won Chan O. Serotonin modulates excitatory synapse maturation in the developing prefrontal cortex. Nature communications. vol 15. issue 1. 2024-02-16. PMID:38365905. |
5-ht release on single spines induced structural and functional long-term potentiation (ltp), requiring both 5-ht2a and 5-ht7 receptor signals, in a glutamatergic activity-independent manner. |
2024-02-16 |
2024-02-19 |
mouse |
| b' Paola Giuliano, Giuliana La Rosa, Serena Capozzi, Emanuele Cassano, Simona Damiano, Francesco Habetswallner, Rosa Iodice, Maurizio Marra, Luigi Michele Pavone, Mario Quarantelli, Giuseppe Vitelli, Mariarosaria Santillo, Roberto Patern\\xc3\\xb. A Blood Test for the Diagnosis of Multiple Sclerosis. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338973.' |
in this study, since there is evidence connecting the serotonin pathway to ms, we used an elisa (enzyme-linked immunosorbent assay) to detect serum ms-specific auto-antibodies (auto-ab) against the extracellular loop 1 (ecl-1) of the 5-hydroxytryptamine (5-ht) receptor subtype 2a (5-ht2a). |
2024-02-10 |
2024-02-12 |
Not clear |
| Alberto Fernández-Teruel, Toni Cañete, Daniel Sampedro-Viana, Ignasi Oliveras, Rafael Torrubia, Adolf Tobeñ. Contribution of the Roman rat lines/strains to personality neuroscience: neurobehavioral modeling of internalizing/externalizing psychopathologies. Personality neuroscience. vol 6. 2023-12-19. PMID:38107777. |
for example, relative to rla rats, rhas exhibit decreased function of the prefrontal cortex (pfc), hippocampus and amygdala, increased functional tone of the mesolimbic dopamine system, a deficit of central metabotropic glutamate-2 (mglu2) receptors, increased density of serotonin 5-ht2a receptors in the pfc, impairment of gabaergic transmission in the pfc, alterations of several synaptic markers and increased density of pyramidal immature dendrític spines in the pfc. |
2023-12-19 |
2023-12-21 |
rat |
| Hector Vargas-Perez, Fernando Minauro-Sanmiguel, Ryan Ting-A-Kee, Taryn Elizabeth Grieder, Mónica Méndez-Díaz, Oscar E Prospéro-García, Derek van der Koo. Rewarding effects in 4-AcO-DMT administration and withdrawal in rats: A challenge to the opponent-process theory. Neuroscience letters. 2023-12-18. PMID:38110146. |
however, current observational and experimental evidence suggests that the administration of a 5-hydroxytryptamine receptors-type 2a (5-ht2a) agonist, while capable of inducing a positive mental state in humans, may not generate the behavioral patterns typically associated with drugs of abuse. |
2023-12-18 |
2023-12-21 |
rat |
| Polona Rus Prelog, Anja Kokalj Palandaci. Hypersexuality during treatment with cariprazine in a patient with schizophrenia? A case report. BMC psychiatry. vol 23. issue 1. 2023-12-11. PMID:38082232. |
it functions as a partial agonist with high affinity for dopamine d2 and d3 and serotonin 5-ht1a receptors, an antagonist for 5-ht2a (moderate affinity) and 5-ht2b (high affinity) receptors. |
2023-12-11 |
2023-12-17 |
Not clear |
| Jeong-Hee Kim, Hang-Keun Kim, Young-Don Son, Jong-Hoon Ki. In Vivo Serotonin 5-HT2A Receptor Availability and Its Relationship with Aggression Traits in Healthy Individuals: A Positron Emission Tomography Study with C-11 MDL100907. International journal of molecular sciences. vol 24. issue 21. 2023-11-14. PMID:37958691. |
in vivo serotonin 5-ht2a receptor availability and its relationship with aggression traits in healthy individuals: a positron emission tomography study with c-11 mdl100907. |
2023-11-14 |
2023-11-20 |
human |
| Vladimir M Pogorelov, Ramona M Rodriguiz, Bryan L Roth, William C Wetse. The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice. Frontiers in molecular biosciences. vol 10. 2023-10-30. PMID:37900918. |
the g protein biased serotonin 5-ht2a receptor agonist lisuride exerts anti-depressant drug-like activities in mice. |
2023-10-30 |
2023-11-08 |
mouse |
| Raly James Perez Custodio, Darlene Mae Ortiz, Hyun Jun Lee, Leandro Val Sayson, Mikyung Kim, Yong Sup Lee, Kyeong-Man Kim, Jae Hoon Cheong, Hee Jin Ki. Serotonin 2C receptors are also important in head-twitch responses in male mice. Psychopharmacology. 2023-10-26. PMID:37882810. |
serotonergic psychedelics exert their effects via their high affinity for serotonin (5-ht) receptors, particularly through activating 5-ht2a receptors (5-ht2ar), employing the frontal cortex-dependent head-twitch response (htr). |
2023-10-26 |
2023-11-08 |
mouse |
| Sanjay Karki, Mehdi Saadaoui, Valentin Dunsing, Stephen Kerridge, Elise Da Silva, Jean-Marc Philippe, Cédric Maurange, Thomas Lecui. Serotonin signaling regulates actomyosin contractility during morphogenesis in evolutionarily divergent lineages. Nature communications. vol 14. issue 1. 2023-09-08. PMID:37684231. |
we find that serotonin and serotonin receptors 5ht2a and 5ht2b form a signaling module that quantitatively regulates the amplitude of planar polarized myoii contractility specified by toll receptors and the gpcr cirl. |
2023-09-08 |
2023-10-07 |
chicken |
| Francesco Tortora, Abed L Hadipour, Simone Battaglia, Alessandra Falzone, Alessio Avenanti, Carmelo M Vicari. The Role of Serotonin in Fear Learning and Memory: A Systematic Review of Human Studies. Brain sciences. vol 13. issue 8. 2023-08-26. PMID:37626553. |
the results suggest that elevated levels of 5-ht enhance aversive learning, indicating that the modulation of serotonin 5-ht2a receptors regulates the expression of fear responses in humans. |
2023-08-26 |
2023-09-07 |
human |
| Ángeles Prados-Pardo, Elena Martín-González, Santiago Mora, Carlos Martín, Manuela Olmedo-Córdoba, Cristian Pérez-Fernandez, Fernando Sánchez-Santed, Margarita Moreno-Montoy. Reduced Expression of the Htr2a, Grin1, and Bdnf Genes and Cognitive Inflexibility in a Model of High Compulsive Rats. Molecular neurobiology. 2023-07-31. PMID:37523044. |
the compulsive hd rats showed cognitive inflexibility and reduced serotonin 2a (5-ht2a) receptor binding levels in the frontal cortex (fc). |
2023-07-31 |
2023-08-14 |
rat |
| Muhammad Ishrat Husain, Daniel M Blumberger, David J Castle, Nicole Ledwos, Elise Fellows, Brett D M Jones, Abigail Ortiz, Stefan Kloiber, Wei Wang, Joshua D Rosenblat, Benoit H Mulsan. Psilocybin for treatment-resistant depression without psychedelic effects: study protocol for a 4-week, double-blind, proof-of-concept randomised controlled trial. BJPsych open. vol 9. issue 4. 2023-07-25. PMID:37489299. |
these effects depend on serotonin 2a (5-ht2a) receptor activation, which can be blocked by 5-ht2a receptor antagonists like ketanserin or risperidone. |
2023-07-25 |
2023-08-14 |
Not clear |
| Barbara G Ferri, Cintia O de Novais, Raquel S Bonani, Wellington A de Barros, Ângelo de Fátima, Fabiana C Vilela, Alexandre Giusti-Paiv. Psychoactive substances 25H-NBOMe and 25H-NBOH induce antidepressant-like behavior in male rats. European journal of pharmacology. 2023-07-21. PMID:37479015. |
ring-substituted phenethylamines are believed to induce psychedelic effects primarily by interacting with 5-hydroxytryptamine 2 (5-ht2a) receptors in the brain. |
2023-07-21 |
2023-08-14 |
rat |
| Rika Takaba, Daisuke Ibi, Keisuke Yoshida, Eri Hosomi, Ririna Kawase, Hiroko Kitagawa, Hirotaka Goto, Mizuki Achiwa, Kento Mizutani, Kyosuke Maede, Javier González-Maeso, Shinji Kitagaki, Masayuki Hiramats. Ethopharmacological evaluation of antidepressant-like effect of serotonergic psychedelics in C57BL/6J male mice. Research square. 2023-07-18. PMID:37461593. |
serotonergic psychedelics such as psilocybin, lysergic acid diethylamide, and doi exert a hallucinatory effect through serotonin 5-ht 2a receptor (5-ht2a) activation. |
2023-07-18 |
2023-08-14 |
mouse |