All Relations between 5-ht receptor 2a and serotonin

Publication Sentence Publish Date Extraction Date Species
Filip Tylš, Tomáš Páleníček, Lukáš Kadeřábek, Michaela Lipski, Anna Kubešová, Jiří Horáče. Sex differences and serotonergic mechanisms in the behavioural effects of psilocin. Behavioural pharmacology. vol 27. issue 4. 2017-11-20. PMID:26461483. the contribution of serotonin receptors in the behavioural action was tested in male rats with selective serotonin receptor antagonists: 5-ht1a receptor antagonist (way100635 1 mg/kg), 5-ht2a receptor antagonist (mdl100907 0.5 mg/kg), 5-ht2b receptor antagonist (sb215505 1 mg/kg) and 5-ht2c receptor antagonist (sb242084 1 mg/kg). 2017-11-20 2023-08-13 rat
Matthew L Bank. Effects of 7-day repeated treatment with the 5-HT2A inverse agonist/antagonist pimavanserin on methamphetamine vs. food choice in male rhesus monkeys. Drug and alcohol dependence. vol 165. 2017-10-03. PMID:27242287. emerging data suggest that serotonin (5-ht)2a receptors modulate mesolimbic dopamine function, such that 5-ht2a antagonists blunt the abuse-related neurochemical effects of monoamine transporter substrates, such as amphetamine or methamphetamine. 2017-10-03 2023-08-13 monkey
C William Heise, Hannah Malashock, Daniel E Brook. A review of vilazodone exposures with focus on serotonin syndrome effects. Clinical toxicology (Philadelphia, Pa.). vol 55. issue 9. 2017-09-11. PMID:28594246. serotonin syndrome is believed to be due to excessive stimulation of 5-ht2a and 5-ht1a receptors, resulting in the clinical triad of altered mentation, autonomic instability and neuromuscular abnormalities. 2017-09-11 2023-08-13 Not clear
Youngjae Ryu, Toru Ogata, Motoshi Nagao, Taku Kitamura, Kazuhito Morioka, Yoshinori Ichihara, Toru Doi, Yasuhiro Sawada, Masami Akai, Ryohei Nishimura, Naoki Fujit. The swimming test is effective for evaluating spasticity after contusive spinal cord injury. PloS one. vol 12. issue 2. 2017-08-28. PMID:28182676. subsequently, we recorded the hoffman reflex (h-reflex) and examined the immunoreactivity of serotonin (5-ht) and its receptor (5-ht2a) in the spinal tissues of the sci rats. 2017-08-28 2023-08-13 rat
Mustafa Küçükköse, Bürge Kabukçu Başa. [Acute Dystonia due to Aripiprazole Use in Two Children with Autism Spectrum Disorder in the First Five Years of Life]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 28. issue 1. 2017-08-28. PMID:28291301. aripiprazole is a partial agonist for the dopamine d2, serotonin 5-ht1a receptors, and an antagonist for 5ht2a receptors. 2017-08-28 2023-08-13 Not clear
Feipu Yang, Xiangrui Jiang, Jianfeng Li, Yu Wang, Yongjian Liu, Minghao Bi, Chunhui Wu, Qingjie Zhao, Weiming Chen, Jingjing Yin, Jian Zhang, Yuanchao Xie, Tianwen Hu, Mingshuo Xu, Shuang Guo, Zhen Wang, Yang He, Jingshan She. Synthesis, structure-activity relationships, and biological evaluation of a series of benzamides as potential multireceptor antipsychotics. Bioorganic & medicinal chemistry letters. vol 26. issue 13. 2017-07-18. PMID:27173799. in the present study, a series of benzamides, endowed with potent dopamine d2, serotonin 5-ht1a and 5-ht2a receptors properties, was synthesized and evaluated as potential antipsychotics. 2017-07-18 2023-08-13 Not clear
Karolina Noworyta-Sokołowska, Katarzyna Kamińska, Grzegorz Kreiner, Zofia Rogóż, Krystyna Gołembiowsk. Neurotoxic Effects of 5-MeO-DIPT: A Psychoactive Tryptamine Derivative in Rats. Neurotoxicity research. vol 30. issue 4. 2017-07-18. PMID:27461536. in vitro data have shown that 5-meo-dipt acts as a potent serotonin transporter (sert) inhibitor and displays high affinity at serotonin 5-ht1a, 5-ht2a, and 5-ht2c receptors. 2017-07-18 2023-08-13 rat
Bing Li, Xiumei Luo, Tao Li, Changyue Zheng, Shunmei Ji, Yuanyuan Ma, Shuangshuang Zhang, Xiaodong Zho. Effects of Constant Flickering Light on Refractive Status, 5-HT and 5-HT2A Receptor in Guinea Pigs. PloS one. vol 11. issue 12. 2017-06-29. PMID:27959948. effects of constant flickering light on refractive status, 5-ht and 5-ht2a receptor in guinea pigs. 2017-06-29 2023-08-13 Not clear
Bing Li, Xiumei Luo, Tao Li, Changyue Zheng, Shunmei Ji, Yuanyuan Ma, Shuangshuang Zhang, Xiaodong Zho. Effects of Constant Flickering Light on Refractive Status, 5-HT and 5-HT2A Receptor in Guinea Pigs. PloS one. vol 11. issue 12. 2017-06-29. PMID:27959948. to investigate the effects of constant flickering light on refractive development, the role of serotonin (i.e.5-hydroxytryptamine, 5-ht)and 5-ht2a receptor in myopia induced by flickering light in guinea pigs. 2017-06-29 2023-08-13 Not clear
Robert E Davis, Christoph U Correl. ITI-007 in the treatment of schizophrenia: from novel pharmacology to clinical outcomes. Expert review of neurotherapeutics. vol 16. issue 6. 2017-06-27. PMID:27042868. iti-007 has a unique pharmacological profile, combining potent 5-ht2a receptor antagonism with cell-type-specific dopamine and glutamate receptor modulation, plus serotonin reuptake inhibition. 2017-06-27 2023-08-13 Not clear
Chang Xu, Xin-Ming Ma, Hui-Bin Chen, Meng-He Zhou, Hui Qiao, Shu-Cheng A. Orbitofrontal cortex 5-HT2A receptor mediates chronic stress-induced depressive-like behaviors and alterations of spine density and Kalirin7. Neuropharmacology. vol 109. 2017-06-19. PMID:26921771. the aim of this study was to investigate the role of orbitofrontal 5-ht and 5-ht2a receptors in depressive-like behaviors and their associations with kal7 and dendritic spines using chronic unpredictable mild stress (cums), an established animal model of depression. 2017-06-19 2023-08-13 rat
Chang Xu, Xin-Ming Ma, Hui-Bin Chen, Meng-He Zhou, Hui Qiao, Shu-Cheng A. Orbitofrontal cortex 5-HT2A receptor mediates chronic stress-induced depressive-like behaviors and alterations of spine density and Kalirin7. Neuropharmacology. vol 109. 2017-06-19. PMID:26921771. cums had no effect on the levels of 5-ht or the 5-ht2a receptor in the ofc. 2017-06-19 2023-08-13 rat
Gongliang Zhang, David Cinalli, Sarah J Cohen, Kristina D Knapp, Lisa M Rios, José Martínez-Hernández, Rafael Luján, Robert W Stackma. Examination of the hippocampal contribution to serotonin 5-HT2A receptor-mediated facilitation of object memory in C57BL/6J mice. Neuropharmacology. vol 109. 2017-06-19. PMID:27114257. examination of the hippocampal contribution to serotonin 5-ht2a receptor-mediated facilitation of object memory in c57bl/6j mice. 2017-06-19 2023-08-13 mouse
Gongliang Zhang, David Cinalli, Sarah J Cohen, Kristina D Knapp, Lisa M Rios, José Martínez-Hernández, Rafael Luján, Robert W Stackma. Examination of the hippocampal contribution to serotonin 5-HT2A receptor-mediated facilitation of object memory in C57BL/6J mice. Neuropharmacology. vol 109. 2017-06-19. PMID:27114257. serotonin 5-ht2a receptors (5-ht2ar) are widely expressed throughout the hippocampus. 2017-06-19 2023-08-13 mouse
Gaël Qesseveur, Anne Cécile Petit, Hai Thanh Nguyen, Lionel Dahan, Romain Colle, Samuel Rotenberg, Isabelle Seif, Pauline Robert, Denis David, Jean-Philippe Guilloux, Alain M Gardier, Céline Verstuyft, Laurent Becquemont, Emmanuelle Corruble, Bruno P Guiar. Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach. Neuropharmacology. vol 105. 2017-06-13. PMID:26764241. pharmacological studies have yielded valuable insights into the role of the serotonin 2a (5-ht2a) receptor in major depressive disorder (mdd) and antidepressant drugs (ads) response. 2017-06-13 2023-08-13 mouse
Gaël Qesseveur, Anne Cécile Petit, Hai Thanh Nguyen, Lionel Dahan, Romain Colle, Samuel Rotenberg, Isabelle Seif, Pauline Robert, Denis David, Jean-Philippe Guilloux, Alain M Gardier, Céline Verstuyft, Laurent Becquemont, Emmanuelle Corruble, Bruno P Guiar. Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach. Neuropharmacology. vol 105. 2017-06-13. PMID:26764241. however, while the chronic administration of the ssris escitalopram or fluoxetine elicited a progressive increased in the firing rate of 5-ht neurons in 5-ht2a(+/+) mice, it failed to do so in 5-ht2a(-/-) mutants. 2017-06-13 2023-08-13 mouse
M Y Liu, L J Zhang, M C Li. [Effect of ginsenoside pre-treatment on 5-hydroxytryptamine system in SD rats with myocardial infarction and depression]. Zhonghua nei ke za zhi. vol 55. issue 9. 2017-06-08. PMID:27586978. to evaluate the effect of ginsenoside pre-treatment on serotonin (5-hydroxytryptamine, 5-ht), 5-ht2a receptor (5-ht2ar), and 5-ht transporter (serotonin transporter, sert) in serum, platelet lysate and brain tissue homogenates in sd rats with myocardial infarction (mi) or depression. 2017-06-08 2023-08-13 rat
E M A Macedo, W C Santos, B P Sousa, E M Lopes, C A Piauilino, F V M Cunha, D P Sousa, F A Oliveira, F R C Almeid. Association of terpinolene and diclofenac presents antinociceptive and anti-inflammatory synergistic effects in a model of chronic inflammation. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 49. issue 7. 2017-05-26. PMID:27332775. a possible mechanism of action of the analgesic effect is the involvement of 5-ht2a serotonin receptors, because ketanserin completely reversed the antinociceptive effect of the tpl/dcf association. 2017-05-26 2023-08-13 rat
Meysam Amidfar, Yong-Ku Kim, Lejla Colic, Mohammad Arbabi, Gholamhossein Mobaraki, Gholamreza Hassanzadeh, Martin Walte. Increased levels of 5HT2A receptor mRNA expression in peripheral blood mononuclear cells of patients with major depression: correlations with severity and duration of illness. Nordic journal of psychiatry. vol 71. issue 4. 2017-05-26. PMID:28125323. neuroimaging, immunologic, and pharmacologic studies have emphasized the role of 5-ht2a and 5-ht3a serotonin receptors in the pathophysiology of major depression. 2017-05-26 2023-08-13 Not clear
Kendra H Oliver, Matthew T Duvernay, Heidi E Hamm, Ana M D Carneir. Loss of Serotonin Transporter Function Alters ADP-mediated Glycoprotein αIIbβ3 Activation through Dysregulation of the 5-HT2A Receptor. The Journal of biological chemistry. vol 291. issue 38. 2017-05-12. PMID:27422820. loss of serotonin transporter function alters adp-mediated glycoprotein αiibβ3 activation through dysregulation of the 5-ht2a receptor. 2017-05-12 2023-08-13 mouse