All Relations between 5-ht receptor 2a and serotonin

Publication Sentence Publish Date Extraction Date Species
Jade M Franklin, Matt Mathew, Gonzalo A Carrasc. Cannabinoid-induced upregulation of serotonin 2A receptors in the hypothalamic paraventricular nucleus and anxiety-like behaviors in rats. Neuroscience letters. vol 548. 2014-02-07. PMID:23721787. recent behavioral reports suggest that repeated exposure to cannabis and synthetic cannabinoid agonists is linked with mental disorders associated with dysfunction of serotonin 2a (5-ht2a) receptor neurotransmission such as anxiety and depression. 2014-02-07 2023-08-12 rat
Kürşat Altınbaş, Sinan Guloksuz, Esat Timuçin Ora. Clinical potential of cariprazine in the treatment of acute mania. Psychiatria Danubina. vol 25. issue 3. 2014-02-06. PMID:24048386. cariprazine has also moderate affinity for serotonin 5-hydroxytryptophan (5-ht) 1a receptors, high affinity for 5-ht1b receptors with pure antagonism and low affinity for 5-ht2a receptors. 2014-02-06 2023-08-12 Not clear
Takeyuki Iwasaki, Ken-ichi Otsuguro, Takeshi Kobayashi, Toshio Ohta, Shigeo It. Endogenously released 5-HT inhibits A and C fiber-evoked synaptic transmission in the rat spinal cord by the facilitation of GABA/glycine and 5-HT release via 5-HT(2A) and 5-HT(3) receptors. European journal of pharmacology. vol 702. issue 1-3. 2014-02-04. PMID:23399761. these results suggest that 5-ht released by pca activates 5-ht2a receptors, which in turn stimulates the release of gaba/glycine and thereby blocks the spinal nociceptive pathway. 2014-02-04 2023-08-12 rat
Yu Chen, Grazyna Palczewska, Debarshi Mustafi, Marcin Golczak, Zhiqian Dong, Osamu Sawada, Tadao Maeda, Akiko Maeda, Krzysztof Palczewsk. Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration. The Journal of clinical investigation. vol 123. issue 12. 2014-02-04. PMID:24231350. focusing on adrenergic (ar) and serotonin (5-ht) receptors, we found that adrenoceptor α 2c (adra2c) and serotonin receptor 2a (htr2a) were the most highly expressed. 2014-02-04 2023-08-12 mouse
Anja Cerovecki, Richard Musil, Ansgar Klimke, Florian Seemüller, Ekkehard Haen, Rebecca Schennach, Kai-Uwe Kühn, Hans-Peter Volz, Michael Riede. Withdrawal symptoms and rebound syndromes associated with switching and discontinuing atypical antipsychotics: theoretical background and practical recommendations. CNS drugs. vol 27. issue 7. 2014-02-03. PMID:23821039. all share the ability to block dopamine d₂ receptors, and most of them also block serotonin 5-ht2a receptors. 2014-02-03 2023-08-12 Not clear
Abraham Martín, Boguslaw Szczupak, Vanessa Gómez-Vallejo, Sandra Plaza, Daniel Padró, Ainhoa Cano, Jordi Llo. PET imaging of serotoninergic neurotransmission with [(11)C]DASB and [(18)F]altanserin after focal cerebral ischemia in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 12. 2014-02-03. PMID:23982048. in the ischemic territory, pet with [(11)c]dasb and [(18)f]altanserin showed a dramatic decline in serotonin transporter (sert) and 5-ht2a binding potential in the cortex and striatum after cerebral ischemia. 2014-02-03 2023-08-12 rat
Christinna V Jørgensen, Jacob P Jacobsen, Marc G Caron, Anders B Klein, Gitte M Knudsen, Jens D Mikkelse. Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice. Neuroscience letters. vol 555. 2014-01-31. PMID:24055299. these data show that in distinct anatomical regions, 5-ht2a receptor binding sites are up-regulated in 5-ht deficient mice, and this increase is not associated with changes in mglur2 binding. 2014-01-31 2023-08-12 mouse
Yinghua Yu, Yizhen Wu, Craig Patch, Zhixiang Wu, Alexander Szabo, Duo Li, Xu-Feng Huan. DHA prevents altered 5-HT1A, 5-HT2A, CB1 and GABAA receptor binding densities in the brain of male rats fed a high-saturated-fat diet. The Journal of nutritional biochemistry. vol 24. issue 7. 2014-01-29. PMID:23337348. the aim of this study was to investigate serotonin receptor (5-ht(1a) and 5-ht2a), cannabinoid receptor (cb1) and gamma-aminobutyric acid type a (gaba(a)) receptor binding densities in the brain of male rats fed a high-saturated-fat (hf) diet, as well as the effect of dha supplementation on hf diet. 2014-01-29 2023-08-12 rat
Yinghua Yu, Yizhen Wu, Craig Patch, Zhixiang Wu, Alexander Szabo, Duo Li, Xu-Feng Huan. DHA prevents altered 5-HT1A, 5-HT2A, CB1 and GABAA receptor binding densities in the brain of male rats fed a high-saturated-fat diet. The Journal of nutritional biochemistry. vol 24. issue 7. 2014-01-29. PMID:23337348. this study showed that an hf diet increased 5-ht(1a), 5-ht2a, cb1 and gaba(a) receptor binding densities in the brain regions involved in cognitive function and that dietary dha can attenuate such alterations. 2014-01-29 2023-08-12 rat
Shannon R Murphy, Edward S Schelegle, Lisa A Miller, Dallas M Hyde, Laura S Van Winkl. Ozone exposure alters serotonin and serotonin receptor expression in the developing lung. Toxicological sciences : an official journal of the Society of Toxicology. vol 134. issue 1. 2014-01-28. PMID:23570994. we hypothesized that ozone exposure alters the normal pattern of serotonin, its transporter (5-htt), and two key receptors (5-ht2a and 5-ht4), a pathway involved in postnatal airway neural, epithelial, and immune processes. 2014-01-28 2023-08-12 monkey
Shannon R Murphy, Edward S Schelegle, Lisa A Miller, Dallas M Hyde, Laura S Van Winkl. Ozone exposure alters serotonin and serotonin receptor expression in the developing lung. Toxicological sciences : an official journal of the Society of Toxicology. vol 134. issue 1. 2014-01-28. PMID:23570994. ozone exposure increases serotonin in airway epithelium regardless of airway level, age, and exposure history and changes the spatial pattern of serotonin receptor protein (5-ht2a and 5-ht4) and 5-htt gene expression depending on compartment, age, and exposure history. 2014-01-28 2023-08-12 monkey
John P Dougherty, Jeff Oristagli. Chronic treatment with the serotonin 2A/2C receptor antagonist SR 46349B enhances the retention and efficiency of rule-guided behavior in mice. Neurobiology of learning and memory. vol 103. 2014-01-24. PMID:23587729. animal studies have established that drugs activating the serotonin 2a (5-ht2a) receptor can enhance learning and memory in a variety of classical and operant conditioning tasks. 2014-01-24 2023-08-12 mouse
Clinton E Canal, Tania Cordova-Sintjago, Yue Liu, Myong S Kim, Drake Morgan, Raymond G Boot. Molecular pharmacology and ligand docking studies reveal a single amino acid difference between mouse and human serotonin 5-HT2A receptors that impacts behavioral translation of novel 4-phenyl-2-dimethylaminotetralin ligands. The Journal of pharmacology and experimental therapeutics. vol 347. issue 3. 2014-01-23. PMID:24080681. molecular pharmacology and ligand docking studies reveal a single amino acid difference between mouse and human serotonin 5-ht2a receptors that impacts behavioral translation of novel 4-phenyl-2-dimethylaminotetralin ligands. 2014-01-23 2023-08-12 mouse
Jeanette Sigurdh, Per Allard, Olav Spigset, Bruno Hägglö. Platelet serotonin transporter and 5-HT2A receptor binding in adolescents with eating disorders. The International journal of neuroscience. vol 123. issue 5. 2014-01-21. PMID:23360120. platelet serotonin transporter and 5-ht2a receptor binding in adolescents with eating disorders. 2014-01-21 2023-08-12 human
Jeanette Sigurdh, Per Allard, Olav Spigset, Bruno Hägglö. Platelet serotonin transporter and 5-HT2A receptor binding in adolescents with eating disorders. The International journal of neuroscience. vol 123. issue 5. 2014-01-21. PMID:23360120. [(3)h]paroxetine binding to the platelet serotonin transporter and [(3)h]lysergic acid diethylamide ([(3)h]lsd) binding to the 5-ht2a receptor was studied in 15 female adolescents with eating disorders (11 with anorexia nervosa and 4 with clearly anorectic eating behaviour not fulfilling the criteria for anorexia nervosa) and 32 controls. 2014-01-21 2023-08-12 human
Jeanette Sigurdh, Per Allard, Olav Spigset, Bruno Hägglö. Platelet serotonin transporter and 5-HT2A receptor binding in adolescents with eating disorders. The International journal of neuroscience. vol 123. issue 5. 2014-01-21. PMID:23360120. the patients revealed a higher density of serotonin transporters and a lower density of 5-ht2a receptors compared with healthy controls of the same age (775 ± 165 vs. 614 ± 111 fmol/mg protein (p = 0.003) for [(3)h]paroxetine binding and 215 ± 59 vs. 314 ± 151 fmol/mg protein (p = 0.005) for [(3)h]lsd binding). 2014-01-21 2023-08-12 human
Jeanette Sigurdh, Per Allard, Olav Spigset, Bruno Hägglö. Platelet serotonin transporter and 5-HT2A receptor binding in adolescents with eating disorders. The International journal of neuroscience. vol 123. issue 5. 2014-01-21. PMID:23360120. the findings of increased density of platelet serotonin transporters and reduced density of 5-ht2a receptors differ from previous results in older patients. 2014-01-21 2023-08-12 human
S Body, T H C Cheung, L Valencia-Torres, C M Olarte-Sánchez, K C F Fone, C M Bradshaw, E Szabad. Pharmacological studies of performance on the free-operant psychophysical procedure. Behavioural processes. vol 95. 2014-01-21. PMID:23428704. t50 is reduced by acute treatment with 5-hydroxytryptamine (5-ht1a, 5-ht2a) and dopamine (d1-like, d2-like) receptor agonists. 2014-01-21 2023-08-12 Not clear
S Body, T H C Cheung, L Valencia-Torres, C M Olarte-Sánchez, K C F Fone, C M Bradshaw, E Szabad. Pharmacological studies of performance on the free-operant psychophysical procedure. Behavioural processes. vol 95. 2014-01-21. PMID:23428704. evidence is reviewed suggesting that the effect of endogenous 5-ht is mediated by 5-ht2a receptors and the effect of endogenous dopamine by d1-like receptors. 2014-01-21 2023-08-12 Not clear
O Lairez, T Cognet, S Schaak, D Calise, C Guilbeau-Frugier, A Parini, J Mialet-Pere. Role of serotonin 5-HT2A receptors in the development of cardiac hypertrophy in response to aortic constriction in mice. Journal of neural transmission (Vienna, Austria : 1996). vol 120. issue 6. 2014-01-10. PMID:23543114. role of serotonin 5-ht2a receptors in the development of cardiac hypertrophy in response to aortic constriction in mice. 2014-01-10 2023-08-12 mouse