| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Body, T H C Cheung, L Valencia-Torres, C M Olarte-Sánchez, K C F Fone, C M Bradshaw, E Szabad. Pharmacological studies of performance on the free-operant psychophysical procedure. Behavioural processes. vol 95. 2014-01-21. PMID:23428704. |
evidence is reviewed suggesting that the effect of endogenous 5-ht is mediated by 5-ht2a receptors and the effect of endogenous dopamine by d1-like receptors. |
2014-01-21 |
2023-08-12 |
Not clear |
| O Lairez, T Cognet, S Schaak, D Calise, C Guilbeau-Frugier, A Parini, J Mialet-Pere. Role of serotonin 5-HT2A receptors in the development of cardiac hypertrophy in response to aortic constriction in mice. Journal of neural transmission (Vienna, Austria : 1996). vol 120. issue 6. 2014-01-10. PMID:23543114. |
role of serotonin 5-ht2a receptors in the development of cardiac hypertrophy in response to aortic constriction in mice. |
2014-01-10 |
2023-08-12 |
mouse |
| O Lairez, T Cognet, S Schaak, D Calise, C Guilbeau-Frugier, A Parini, J Mialet-Pere. Role of serotonin 5-HT2A receptors in the development of cardiac hypertrophy in response to aortic constriction in mice. Journal of neural transmission (Vienna, Austria : 1996). vol 120. issue 6. 2014-01-10. PMID:23543114. |
5-ht2a receptors are expressed in the heart and mediate a hypertrophic response to 5-ht in cardiac cells. |
2014-01-10 |
2023-08-12 |
mouse |
| Alexander W Frere, M Danielle McDonal. The effect of stress on gill basolateral membrane binding kinetics of 5-ht2 receptor ligands: potential implications for urea excretion mechanisms. Journal of experimental zoology. Part A, Ecological genetics and physiology. vol 319. issue 5. 2013-12-31. PMID:23495168. |
the goal of this study was to determine the relationship between cortisol and the toadfish serotonin 2a (5-ht2a ) receptor, which is believed to be responsible for the activation of the toadfish urea transporter, tut. |
2013-12-31 |
2023-08-12 |
Not clear |
| Anders Kling, Tom Mjörndal, Solbritt Rantapää-Dahlqvis. Glucocorticoid treatment increases density of serotonin 5-HT2A receptors in humans. Psychoneuroendocrinology. vol 38. issue 7. 2013-12-30. PMID:23146656. |
glucocorticoid treatment increases density of serotonin 5-ht2a receptors in humans. |
2013-12-30 |
2023-08-12 |
Not clear |
| Anders Kling, Tom Mjörndal, Solbritt Rantapää-Dahlqvis. Glucocorticoid treatment increases density of serotonin 5-HT2A receptors in humans. Psychoneuroendocrinology. vol 38. issue 7. 2013-12-30. PMID:23146656. |
animal studies have shown that the density of serotonin 5-ht2a receptors is increased after administration of exogenous glucocorticoids. |
2013-12-30 |
2023-08-12 |
Not clear |
| Zoya Marinova, Susanne Walitza, Edna Grünblat. 5-HT2A serotonin receptor agonist DOI alleviates cytotoxicity in neuroblastoma cells: role of the ERK pathway. Progress in neuro-psychopharmacology & biological psychiatry. vol 44. 2013-12-18. PMID:23380172. |
disturbances of serotonergic signaling, including the serotonin 2a (5-ht2a) receptor, have been implicated in neuropsychiatric and neurodegenerative disorders. |
2013-12-18 |
2023-08-12 |
human |
| Clara Naimi-Akbar, Markus Ritter, Sasika Demel, Husameldin El-Nour, Mari-Anne Hedblad, Efrain C Azmitia, Klas Nordlin. Different serotonergic expression in nevomelanocytic tumors. Cancers. vol 2. issue 2. 2013-11-27. PMID:24281111. |
for this purpose, paraffin-embedded biopsies of superficial spreading malignant melanoma (ssm), dysplastic compound nevi (dn) and benign compound nevi (bcn) were characterized with regard to their expression of 5-ht, the 5-ht1a and 5-ht2a receptors, and the serotonin transporter protein (sert), by immunohistochemical analysis. |
2013-11-27 |
2023-08-12 |
Not clear |
| Yvonne Couch, Chris J Martin, Clare Howarth, Josie Raley, Alexandre A Khrapitchev, Michael Stratford, Trevor Sharp, Nicola R Sibson, Daniel C Anthon. Systemic inflammation alters central 5-HT function as determined by pharmacological MRI. NeuroImage. vol 75. 2013-11-26. PMID:23473937. |
the resultant phmri data were investigated further through measurements of cortical 5-ht release (microdialysis), and vascular responsivity, as well as a more thorough investigation of the role of the 5-ht2a receptor in sickness behaviour. |
2013-11-26 |
2023-08-12 |
rat |
| Judith R Homber. Serotonergic modulation of conditioned fear. Scientifica. vol 2012. 2013-11-26. PMID:24278743. |
the human and rodent studies i review here together reveal, amongst others, that acute selective serotonin reuptake inhibitor (ssri) treatment facilitates fear conditioning, reduces contextual fear, and increases cued fear, chronic ssri treatment reduces both contextual and cued fear, 5-ht1a receptors inhibit the acquisition and expression of contextual fear, 5-ht2a receptors facilitates the consolidation of cued and contextual fear, inactivation of 5-ht2c receptors facilitate the retrieval of cued fear memory, the 5-ht3 receptor mediates contextual fear, genetically induced increases in serotonin levels are associated with increased fear conditioning, impaired cued fear extinction, or impaired extinction recall, and that genetically induced 5-ht depletion increases fear conditioning and contextual fear. |
2013-11-26 |
2023-08-12 |
human |
| F Jantschak, J Brosda, R T Franke, H Fink, D Möller, H Hübner, P Gmeiner, H H Pert. Pharmacological profile of 2-bromoterguride at human dopamine D2, porcine serotonin 5-hydroxytryptamine 2A, and α2C-adrenergic receptors, and its antipsychotic-like effects in rats. The Journal of pharmacology and experimental therapeutics. vol 347. issue 1. 2013-11-25. PMID:23863695. |
in this study, we used functional assays for recombinant d2 receptors and native 5-hydroxytryptamine 2a (5-ht2a), α2c-adrenergic, and histamine h1 receptors to compare the pharmacological properties of terguride and three of its halogenated derivatives (2-chloro-, 2-bromo-, 2-iodoterguride) with those of aripiprazole. |
2013-11-25 |
2023-08-12 |
human |
| Katharine Herrick-Davis, Ellinor Grinde, Ann Cowan, Joseph E Mazurkiewic. Fluorescence correlation spectroscopy analysis of serotonin, adrenergic, muscarinic, and dopamine receptor dimerization: the oligomer number puzzle. Molecular pharmacology. vol 84. issue 4. 2013-11-25. PMID:23907214. |
six different class a gpcrs were selected from the serotonin (5-ht2a), adrenergic (α1b-ar and β2-ar), muscarinic (m1 and m2), and dopamine (d1) receptor families. |
2013-11-25 |
2023-08-12 |
human |
| Sophie da Cunha-Bang, Dea Siggaard Stenbæk, Klaus Holst, Cecilie Löe Licht, Peter Steen Jensen, Vibe Gedsø Frokjaer, Erik Lykke Mortensen, Gitte Moos Knudse. Trait aggression and trait impulsivity are not related to frontal cortex 5-HT2A receptor binding in healthy individuals. Psychiatry research. vol 212. issue 2. 2013-11-19. PMID:23137806. |
numerous studies indicate that the serotonergic (5-ht) transmitter system is involved in the regulation of impulsive aggression and there is from post-mortem, in vivo imaging and genetic studies evidence that the 5-ht2a receptor may be involved. |
2013-11-19 |
2023-08-12 |
Not clear |
| Naoual Bouzidi, Hemantkumar Deokar, Alexandre Vogrig, Benjamin Boucherle, Isabelle Ripoche, Isabelle Abrunhosa-Thomas, Liam Dorr, Anne-Sophie Wattiez, Lu-Yun Lian, Philippe Marin, Christine Courteix, Sylvie Duck. Identification of PDZ ligands by docking-based virtual screening for the development of novel analgesic agents. Bioorganic & medicinal chemistry letters. vol 23. issue 9. 2013-11-08. PMID:23545111. |
disrupting the interaction between the pdz protein, psd-95, and its target ligands (such as the glutamate nmda receptor or the serotonin 5-ht2a receptor) was found to reduce hyperalgesia in various models of neuropathic pain. |
2013-11-08 |
2023-08-12 |
Not clear |
| Katerina Zavitsanou, Victoria S Dalton, Adam K Walker, Cynthia S Weickert, Luba Sominsky, Deborah M Hodgso. Neonatal lipopolysaccharide treatment has long-term effects on monoaminergic and cannabinoid receptors in the rat. Synapse (New York, N.Y.). vol 67. issue 6. 2013-10-29. PMID:23389966. |
dopamine d1, d2, serotonin 5ht1a, 5ht2a, and serotonin transporter and cannabinoid cb1 receptor binding across several brain regions were measured autoradiographically in adulthood (pnd 85). |
2013-10-29 |
2023-08-12 |
rat |
| Katerina Zavitsanou, Victoria S Dalton, Adam K Walker, Cynthia S Weickert, Luba Sominsky, Deborah M Hodgso. Neonatal lipopolysaccharide treatment has long-term effects on monoaminergic and cannabinoid receptors in the rat. Synapse (New York, N.Y.). vol 67. issue 6. 2013-10-29. PMID:23389966. |
neonatal lps had no significant impact on dopamine d1, serotonin 5ht2a or serotonin transporter binding in any of the brain regions examined. |
2013-10-29 |
2023-08-12 |
rat |
| Hanne D Hansen, Anders Ettrup, Matthias M Herth, Agnete Dyssegaard, Cecilia Ratner, Nic Gillings, Gitte M Knudse. Direct comparison of [(18) F]MH.MZ and [(18) F] altanserin for 5-HT2A receptor imaging with PET. Synapse (New York, N.Y.). vol 67. issue 6. 2013-10-29. PMID:23390031. |
imaging the cerebral serotonin 2a (5-ht2a ) receptors with positron emission tomography (pet) has been carried out in humans with [(11) c]mdl 100907 and [(18) f]altanserin. |
2013-10-29 |
2023-08-12 |
Not clear |
| Stephen M Stahl, Clara Lee-Zimmerman, Sylvia Cartwright, Debbi Ann Morrissett. Serotonergic drugs for depression and beyond. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23531115. |
the original trend to do this selectively (e.g., with ssris or selective serotonin reuptake inhibitors) has given way to combining various additional pharmacologic mechanisms with sert inhibition, including dual actions by single drugs (e.g., snris or serotonin norepinephrine reuptake inhibitors), or by augmenting ssris with a second drug of a different mechanism (e.g., bupropion with dopamine and norepinephrine reuptake inhibition; trazodone with 5ht2a antagonism; mirtazapine with 5ht2a/5ht2c/5ht3/alpha2 antagonism; buspirone or some atypical antipsychotics with 5ht1a partial agonism; other atypical antipsychotics with 5ht2c/5ht7 antagonism and other mechanisms). |
2013-10-29 |
2023-08-12 |
Not clear |
| Takeshi Murai, Tomokazu Nakako, Masaru Ikejiri, Takeo Ishiyama, Mutsuo Taiji, Kazuhito Iked. Effects of lurasidone on executive function in common marmosets. Behavioural brain research. vol 246. 2013-10-28. PMID:23454675. |
lurasidone, a novel atypical antipsychotic agent with high binding affinity for dopamine d2, serotonin 5-ht7, 5-ht2a and 5-ht1a receptors has been reported to have superior efficacy in rodents' models of cognitive impairment. |
2013-10-28 |
2023-08-12 |
Not clear |
| Amber Lockridge, Brett Newland, Spencer Printen, Gabriel E Romero, Li-Lian Yua. Head movement: a novel serotonin-sensitive behavioral endpoint for tail suspension test analysis. Behavioural brain research. vol 246. 2013-10-28. PMID:23499706. |
the use of 5-ht subtype receptor agonists, after depleting endogenous 5-ht with pcpa, shows the head movement suppressing effect of 5-ht2a and 5-ht2c postsynaptic receptor activation. |
2013-10-28 |
2023-08-12 |
mouse |