All Relations between 5-ht receptor 2a and serotonin

Publication Sentence Publish Date Extraction Date Species
Yu-hong Wang, Wen-qiang Li, Zhao Huang, Yu-zhong Shi, Xu-Yi Wang, Jin-song Huang, Xu-hui Zhou, Hong-xian Chen, Wei Ha. 5-HT2A receptor gene polymorphism and negative symptoms in first episode (drug-naive) Chinese Han nationality individuals with schizophrenia. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 33. issue 4. 2009-05-07. PMID:18460771. to investigate whether the 5-hydroxytryptamine 2a receptor (5-ht2a) gene t102c polymorphism is associated with the severity symptoms and negative symptoms in the first episode chinese han nationality patients with schizophrenia. 2009-05-07 2023-08-12 Not clear
Samiye Yabanoglu, Mansour Akkiki, Marie-Helène Seguelas, Jeanne Mialet-Perez, Angelo Parini, Nathalie Pizzina. Platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-HT2A receptors. Journal of molecular and cellular cardiology. vol 46. issue 4. 2009-05-06. PMID:19167402. platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-ht2a receptors. 2009-05-06 2023-08-12 rat
Samiye Yabanoglu, Mansour Akkiki, Marie-Helène Seguelas, Jeanne Mialet-Perez, Angelo Parini, Nathalie Pizzina. Platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-HT2A receptors. Journal of molecular and cellular cardiology. vol 46. issue 4. 2009-05-06. PMID:19167402. treatment of neonatal rat cardiac fibroblasts with platelet lysate, 5-ht and the 5-ht2a receptor agonist doi increased the expression of alpha-sma protein, a marker of fibroblast differentiation into myofibroblasts. 2009-05-06 2023-08-12 rat
Samiye Yabanoglu, Mansour Akkiki, Marie-Helène Seguelas, Jeanne Mialet-Perez, Angelo Parini, Nathalie Pizzina. Platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-HT2A receptors. Journal of molecular and cellular cardiology. vol 46. issue 4. 2009-05-06. PMID:19167402. platelet lysate, 5-ht and doi also induced a time-dependent stimulation of cardiac fibroblast migration that was inhibited by the 5-ht2a receptor antagonist ketanserin. 2009-05-06 2023-08-12 rat
Samiye Yabanoglu, Mansour Akkiki, Marie-Helène Seguelas, Jeanne Mialet-Perez, Angelo Parini, Nathalie Pizzina. Platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-HT2A receptors. Journal of molecular and cellular cardiology. vol 46. issue 4. 2009-05-06. PMID:19167402. 5-ht released by platelets appears to be a major contributor of platelet effects which are mediated through 5-ht2a receptors. 2009-05-06 2023-08-12 rat
Vincenzo De Luca, Emanuela Viggiano, Ranbir Dhoot, James L Kennedy, Albert H C Won. Methylation and QTDT analysis of the 5-HT2A receptor 102C allele: analysis of suicidality in major psychosis. Journal of psychiatric research. vol 43. issue 5. 2009-04-24. PMID:18783799. the serotonin 2a (5-ht2a) receptor gene has been implicated in the pathogenesis of suicidal behaviour by a genetic association between the 5-ht2a t102c silent polymorphism and suicidality in patients with mood disorders and schizophrenia. 2009-04-24 2023-08-12 human
Chiung-Wen Chang, Ethan Poteet, John A Schetz, Zeynep H Gümüş, Harel Weinstei. Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activation. Neuropharmacology. vol 56 Suppl 1. 2009-04-15. PMID:18762202. through a multidisciplinary approach involving experimental and computational studies, we address quantitative aspects of signaling mechanisms triggered in the cell by the receptor targets of hallucinogenic drugs, the serotonin 5-ht2a receptors. 2009-04-15 2023-08-12 Not clear
Chiung-Wen Chang, Ethan Poteet, John A Schetz, Zeynep H Gümüş, Harel Weinstei. Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activation. Neuropharmacology. vol 56 Suppl 1. 2009-04-15. PMID:18762202. to reveal the properties of the signaling pathways, and the way in which responses elicited through these receptors alone and in combination with other serotonin receptors' subtypes (the 5-ht1ar), we developed a detailed mathematical model of receptor-mediated erk1/2 activation in cells expressing the 5-ht1a and 5-ht2a subtypes individually, and together. 2009-04-15 2023-08-12 Not clear
Francesco Benedetti, Barbara Barbini, Alessandro Bernasconi, Mara Cigala Fulgosi, Cristina Colombo, Sara Dallaspezia, Chiara Gavinelli, Elena Marino, Adele Pirovano, Daniele Radaelli, Enrico Smerald. Serotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 8. 2009-04-15. PMID:18801406. serotonin 5-ht2a receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression. 2009-04-15 2023-08-12 Not clear
Francesco Benedetti, Barbara Barbini, Alessandro Bernasconi, Mara Cigala Fulgosi, Cristina Colombo, Sara Dallaspezia, Chiara Gavinelli, Elena Marino, Adele Pirovano, Daniele Radaelli, Enrico Smerald. Serotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 8. 2009-04-15. PMID:18801406. the higher density of postsynaptic excitatory 5-ht2a receptors in t/t homozygotes could have led to higher behavioural effects of increased 5-ht neurotransmission due to repeated tsd. 2009-04-15 2023-08-12 Not clear
John A Allen, Prem N Yadav, Bryan L Rot. Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases. Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18640136. insights into the regulation of 5-ht2a serotonin receptors by scaffolding proteins and kinases. 2009-04-14 2023-08-12 Not clear
Vanessa de Paula Soares, Hélio Zangross. Stimulation of 5-HT1A or 5-HT2A receptors in the ventrolateral periaqueductal gray causes anxiolytic-, but not panicolytic-like effect in rats. Behavioural brain research. vol 197. issue 1. 2009-04-10. PMID:18801389. moreover, as shown by the results of antagonism studies, 5-ht2a receptors are recruited for the anxiolysis caused by serotonin and doi, while 5-ht1a receptors account for the effect of 8-oh-dpat. 2009-04-10 2023-08-12 rat
M Shahid, G B Walker, S H Zorn, E H F Won. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. Journal of psychopharmacology (Oxford, England). vol 23. issue 1. 2009-04-03. PMID:18308814. in comparison with the antipsychotics, asenapine showed high affinity and a different rank order of binding affinities (pki) for serotonin receptors (5-ht1a [8.6], 5-ht1b [8.4], 5-ht2a [10.2], 5-ht2b [9.8], 5-ht2c [10.5], 5-ht5 [8.8], 5-ht6 [9.6] and 5-ht7 [9.9]), adrenoceptors (alpha1 [8.9], alpha2a [8.9], alpha2b [9.5] and alpha2c [8.9]), dopamine receptors (d1 [8.9], d2 [8.9], d3 [9.4] and d4 [9.0]) and histamine receptors (h1 [9.0] and h2 [8.2]). 2009-04-03 2023-08-12 human
Irismar Reis de Oliveira, Hélio Elkis, Wagner Farid Gattaz, Ana Cristina Chaves, Eduardo Pondé de Sena, Fabio Gomes de Matos E Souza, João Alberto Campos, João Romildo Bueno, Jorge Alberto Costa E Silva, Mário Rodrigues Louzã, Paulo Belmonte de Abre. Aripiprazole for patients with schizophrenia and schizoaffective disorder: an open-label, randomized, study versus haloperidol. CNS spectrums. vol 14. issue 2. 2009-04-01. PMID:19238124. aripiprazole, a dopamine d2 receptor partial agonist, has also partial agonist activity at serotonin (5-ht)1a receptors and antagonist activity at 5-ht2a receptors. 2009-04-01 2023-08-12 Not clear
Arzu Gunes, Kristina I Melkersson, Maria Gabriella Scordo, Marja-Liisa Dah. Association between HTR2C and HTR2A polymorphisms and metabolic abnormalities in patients treated with olanzapine or clozapine. Journal of clinical psychopharmacology. vol 29. issue 1. 2009-03-23. PMID:19142110. serotonin 2c and 2a receptor (5-ht2c and 5-ht2a) antagonisms are hypothesized to play a role in the metabolic adverse effects induced by olanzapine and clozapine. 2009-03-23 2023-08-12 Not clear
Moti L Chapagain, Laarni Sumibcay, Ulziijargal Gurjav, Pakieli H Kaufusi, Richard E Kast, Vivek R Nerurka. Serotonin receptor 2A blocker (risperidone) has no effect on human polyomavirus JC infection of primary human fetal glial cells. Journal of neurovirology. vol 14. issue 5. 2009-03-12. PMID:18989819. a recent report demonstrated that jc virus (jcv) employs serotonin receptor 2a (5ht(2a)r) to infect the glial cells. 2009-03-12 2023-08-12 human
L S Lopes, S S Pereira, L L Silva, K A Figueiredo, B A Moura, F R C Almeida, F C F Sous. Antinociceptive effect of topiramate in models of acute pain and diabetic neuropathy in rodents. Life sciences. vol 84. issue 3-4. 2009-03-10. PMID:19056404. the antinociceptive effect caused by tp (80 mg/kg, p.o) in the formalin test was reversed by prior treatment with naloxone (opioid antagonist), but not with glibenclamide (antagonist of the potassium channel), ondansetron (antagonist of the serotonin 5ht3 receptor) or cyproheptadine (antagonist of the serotonin 5ht2a receptor).the data show that tp has an important antinociceptive effect in the models of nociception induced by chemical (formalin) or thermal (hot plate) stimuli, and that the opioid system plays a part in the antinociceptive effect, as shown by formalin. 2009-03-10 2023-08-12 mouse
Michael H Wiegan. Antidepressants for the treatment of insomnia : a suitable approach? Drugs. vol 68. issue 17. 2009-02-27. PMID:19016570. drugs blocking serotonin 5-ht2a or 5-ht2c receptors should be preferred over those whose sedative property is caused by histamine receptor blockade only. 2009-02-27 2023-08-12 Not clear
J V Wallac. Endogenous hallucinogens as ligands of the trace amine receptors: a possible role in sensory perception. Medical hypotheses. vol 72. issue 1. 2009-02-25. PMID:18805646. additionally, while activity at the serotonin 5-ht2a receptor has been proposed as being responsible for the hallucinogenic affects of administered hallucinogens, in their natural setting the 5-ht2a receptor may not interact with the endogenous hallucinogens at all. 2009-02-25 2023-08-12 Not clear
J V Wallac. Endogenous hallucinogens as ligands of the trace amine receptors: a possible role in sensory perception. Medical hypotheses. vol 72. issue 1. 2009-02-25. PMID:18805646. additionally 5-ht2a agonist activity is unable to account for the visual altering effects of many of the administered hallucinogens; these effects may be mediated by one of the endogenous hallucinogen trace amine receptors rather than the serotonin 5-ht2a receptor. 2009-02-25 2023-08-12 Not clear