| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Javier González-Maeso, Rosalind L Ang, Tony Yuen, Pokman Chan, Noelia V Weisstaub, Juan F López-Giménez, Mingming Zhou, Yuuya Okawa, Luis F Callado, Graeme Milligan, Jay A Gingrich, Marta Filizola, J Javier Meana, Stuart C Sealfo. Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature. vol 452. issue 7183. 2008-04-09. PMID:18297054. |
some antipsychotic drugs were identified by their high affinity for serotonin 5-ht2a receptors (2ar). |
2008-04-09 |
2023-08-12 |
human |
| b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Susanne H M Gruber, Stefan Bren\\xc3\\xa. Social isolation increases number of newly proliferated cells in hippocampus in female flinders sensitive line rats. Hippocampus. vol 17. issue 12. 2008-02-29. PMID:17879375.' |
in an animal model of depression, flinders sensitive line rats, and sprague dawley controls we analyzed if 7 weeks of social isolation of adult animals affect the number of newly proliferated cells in the dentate gyrus or mrnas of neuropeptide y (npy), the npy-y1 receptor, nociceptin, bdnf, and the serotonin 5ht1a and 5ht2a receptors, which are molecules involved in hippocampal plasticity. |
2008-02-29 |
2023-08-12 |
rat |
| b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Susanne H M Gruber, Stefan Bren\\xc3\\xa. Social isolation increases number of newly proliferated cells in hippocampus in female flinders sensitive line rats. Hippocampus. vol 17. issue 12. 2008-02-29. PMID:17879375.' |
group housed sprague dawley rats had a higher expression of bdnf, npy, and the serotonin 5ht2a receptor mrna than "depressed" flinders sensitive line. |
2008-02-29 |
2023-08-12 |
rat |
| Henrik Dam, Erling T Mellerup, Per Plenge, Rosa Winther, Gitta Wörtwei. The serotonin transporter and 5HT2A receptor in rat brain after localized lesions. Neurological research. vol 29. issue 7. 2008-02-19. PMID:17711618. |
the serotonin transporter and 5ht2a receptor in rat brain after localized lesions. |
2008-02-19 |
2023-08-12 |
rat |
| Henrik Dam, Erling T Mellerup, Per Plenge, Rosa Winther, Gitta Wörtwei. The serotonin transporter and 5HT2A receptor in rat brain after localized lesions. Neurological research. vol 29. issue 7. 2008-02-19. PMID:17711618. |
the purpose of the present study was to examine whether serotonin transporter density or 5ht2a serotonin receptor density is changed in specific brain areas following anterior or posterior lesions in the two hemispheres. |
2008-02-19 |
2023-08-12 |
rat |
| Henrik Stig Jørgense. Studies on the neuroendocrine role of serotonin. Danish medical bulletin. vol 54. issue 4. 2008-02-14. PMID:18208678. |
the 5-ht induced prl response is mediated via 5-ht1a, 5-ht2a, 5-ht2c and 5-ht3 receptors. |
2008-02-14 |
2023-08-12 |
rat |
| Henrik Stig Jørgense. Studies on the neuroendocrine role of serotonin. Danish medical bulletin. vol 54. issue 4. 2008-02-14. PMID:18208678. |
the acth response to 5-ht is mediated via 5-ht1a, 5-ht1b, 5-ht2a and 5-ht2c receptors and an involvement of the 5-ht4, 5-ht5 and 5-ht7 receptors is proposed. |
2008-02-14 |
2023-08-12 |
rat |
| Trond Brattelid, Eirik Qvigstad, Jon Arne Kro Birkeland, Fredrik Swift, Silje V S Bekkevold, Kurt A Krobert, Ole M Sejersted, Tor Skomedal, Jan-Bjørn Osnes, Finn Olav Levy, Ivar Sjaasta. Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. Journal of molecular and cellular cardiology. vol 43. issue 6. 2008-02-07. PMID:17936780. |
serotonin responsiveness through 5-ht2a and 5-ht4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. |
2008-02-07 |
2023-08-12 |
human |
| Enzo Emanuele, Natascia Brondino, Sara Pesenti, Simona Re, Diego Gerold. Genetic loading on human loving styles. Neuro endocrinology letters. vol 28. issue 6. 2008-02-07. PMID:18063936. |
to address this issue, we looked for associations between markers in neurotransmitter genes (the serotonin transporter gene, 5-htt; the serotonin receptor 2a, 5ht2a; the dopamine d2 receptor gene, drd2; and the dopamine d4 receptor gene, drd4) and the six styles of love as conceptualized by lee (eros, ludus, storge, pragma, mania and agape). |
2008-02-07 |
2023-08-12 |
human |
| Vincent J Aloyo, Kuldip D Dav. Behavioral response to emotional stress in rabbits: role of serotonin and serotonin2A receptors. Behavioural pharmacology. vol 18. issue 7. 2008-01-29. PMID:17912049. |
these data demonstrate that rabbit head-bob behavior, an index of the response to novelty stress, is mediated, in part, by 5-ht activation of 5-ht2a receptors. |
2008-01-29 |
2023-08-12 |
dog |
| Takeo Ishiyama, Kumiko Tokuda, Tadashi Ishibashi, Akira Ito, Satoko Toma, Yukihiro Ohn. Lurasidone (SM-13496), a novel atypical antipsychotic drug, reverses MK-801-induced impairment of learning and memory in the rat passive-avoidance test. European journal of pharmacology. vol 572. issue 2-3. 2008-01-14. PMID:17662268. |
lurasidone (sm-13496) is a novel atypical antipsychotic with high affinities to dopamine d2, serotonin 5-ht7, 5-ht2a, 5-ht1a receptors and alpha2c adrenoceptor. |
2008-01-14 |
2023-08-12 |
rat |
| Kentaro Hamada, Masanori Yoshida, Hiroyuki Isayama, Yoshiki Yagi, Shuichi Kanazashi, Yasunari Kashihara, Koji Takeuchi, Isamu Yamaguch. Possible involvement of endogenous 5-HT in aggravation of cerulein-induced acute pancreatitis in mice. Journal of pharmacological sciences. vol 105. issue 3. 2008-01-10. PMID:17965538. |
while the cerulein-induced hyperenzymemia was attenuated in mice pretreated with p-cpa, a 5-ht depletor, it was exaggerated by the preferential 5-ht2a agonist (doi), but not by the preferential 5-ht2b agonist (bw723c86) or the preferential 5-ht2c agonist (mcpp). |
2008-01-10 |
2023-08-12 |
mouse |
| Kentaro Hamada, Masanori Yoshida, Hiroyuki Isayama, Yoshiki Yagi, Shuichi Kanazashi, Yasunari Kashihara, Koji Takeuchi, Isamu Yamaguch. Possible involvement of endogenous 5-HT in aggravation of cerulein-induced acute pancreatitis in mice. Journal of pharmacological sciences. vol 105. issue 3. 2008-01-10. PMID:17965538. |
these results suggest that endogenously released 5-ht activates 5-ht2a receptors to aggravate cerulein-induced pancreatitis. |
2008-01-10 |
2023-08-12 |
mouse |
| Lei Han, Yong-Mei Zhong, Xiong-Li Yan. 5-HT2A receptors are differentially expressed in bullfrog and rat retinas: a comparative study. Brain research bulletin. vol 73. issue 4-6. 2008-01-07. PMID:17562393. |
expression of 5-hydroxytryptamine (5-ht) 2a receptor (5-ht2a) was studied in bullfrog and rat retinas by immunocytochemistry. |
2008-01-07 |
2023-08-12 |
rat |
| Lei Han, Yong-Mei Zhong, Xiong-Li Yan. 5-HT2A receptors are differentially expressed in bullfrog and rat retinas: a comparative study. Brain research bulletin. vol 73. issue 4-6. 2008-01-07. PMID:17562393. |
these results suggest that 5-ht may modulate retinal information processing via activating 5-ht2a expressed in neuronal and glial elements in bullfrog, but that such modulation is unlikely to occur in rat. |
2008-01-07 |
2023-08-12 |
rat |
| Vivian Bertola, Quirino Cordeiro, Stevin Zung, Elisabete Cristina Miracca, Homero Vallad. Association analysis between the C516T polymorphism in the 5-HT2A receptor gene and schizophrenia. Arquivos de neuro-psiquiatria. vol 65. issue 1. 2008-01-03. PMID:17420819. |
some studies have suggested that the efficacy of atypical antipsychotics on schizophrenia treatment may be related to the serotonin 2a receptor (5-ht2a), and that serotonergic drugs may induce psychotic symptoms. |
2008-01-03 |
2023-08-12 |
Not clear |
| Asheebo Rojas, Junda Su, Liang Yang, Ming Lee, Ningren Cui, Xiaoli Zhang, Dyanna Fountain, Chun Jian. Modulation of the heteromeric Kir4.1-Kir5.1 channel by multiple neurotransmitters via Galphaq-coupled receptors. Journal of cellular physiology. vol 214. issue 1. 2007-12-14. PMID:17559083. |
the firing rate of co(2)-sensitive brainstem neurons cultured in microelectrode arrays was augmented by sp or a 5-ht2a receptor agonist, which was blocked by pkc inhibitors suggesting that pkc underscores the inhibitory effect of sp and 5-ht in cultured brainstem neurons as well. |
2007-12-14 |
2023-08-12 |
human |
| Michael R Braden, David E Nichol. Assessment of the roles of serines 5.43(239) and 5.46(242) for binding and potency of agonist ligands at the human serotonin 5-HT2A receptor. Molecular pharmacology. vol 72. issue 5. 2007-12-13. PMID:17715398. |
assessment of the roles of serines 5.43(239) and 5.46(242) for binding and potency of agonist ligands at the human serotonin 5-ht2a receptor. |
2007-12-13 |
2023-08-12 |
human |
| Xiaoqun Zhang, Per E Andren, Per Svenningsso. Changes on 5-HT2 receptor mRNAs in striatum and subthalamic nucleus in Parkinson's disease model. Physiology & behavior. vol 92. issue 1-2. 2007-12-06. PMID:17588622. |
here, we demonstrate that the genes encoding serotonin 5-ht2a and 5-ht2c receptors are differently regulated by dopamine in the 6-hydroxydopamine (6-ohda) rat model of pd. |
2007-12-06 |
2023-08-12 |
rat |
| b' G V Portnova, O V Sysoeva, N V Maliuchenko, M A Timofeeva, M A Kulikova, A G Tonevitski\\xc4\\xad, M P Kirpichnikov, A M Ivanitski\\xc4\\xa. [Genetic basis of time perception in athletes]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 57. issue 4. 2007-11-30. PMID:17944104.' |
5-ht2a and maoa genes, regulating activity of serotonin, influence on subjective time flow. |
2007-11-30 |
2023-08-12 |
Not clear |