| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Evelyn K Lambe, George K Aghajania. Hallucinogen-induced UP states in the brain slice of rat prefrontal cortex: role of glutamate spillover and NR2B-NMDA receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 8. 2006-08-31. PMID:16292328. |
psychedelic hallucinogens (eg lsd or doi) induce disturbances of mood, perception, and cognition through stimulation of serotonin 5-ht2a receptors. |
2006-08-31 |
2023-08-12 |
rat |
| Dietrich E Lorke, Gang Lu, Eric Cho, David T Ye. Serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients. BMC neuroscience. vol 7. 2006-08-23. PMID:16640790. |
serotonin 5-ht2a and 5-ht6 receptors in the prefrontal cortex of alzheimer and normal aging patients. |
2006-08-23 |
2023-08-12 |
Not clear |
| I P Voronova, A V Kulikov, N K Popova, T V Kozyrev. [Effect of long-term cold adaptation on the mRNA expression of serotonin 5-HT1A and 5-HT2A receptors]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 92. issue 5. 2006-08-18. PMID:16869289. |
[effect of long-term cold adaptation on the mrna expression of serotonin 5-ht1a and 5-ht2a receptors]. |
2006-08-18 |
2023-08-12 |
rat |
| I P Voronova, A V Kulikov, N K Popova, T V Kozyrev. [Effect of long-term cold adaptation on the mRNA expression of serotonin 5-HT1A and 5-HT2A receptors]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 92. issue 5. 2006-08-18. PMID:16869289. |
the mrna expression of serotonin receptors 5-ht1a and 5-ht2a was investigated by the quantitative method rt-pcr in rats adapted to cold (5 weeks at +4 -(+6) degrees c) and in control (5 weeks at +20-22 degrees c). |
2006-08-18 |
2023-08-12 |
rat |
| Harel Weinstei. Hallucinogen actions on 5-HT receptors reveal distinct mechanisms of activation and signaling by G protein-coupled receptors. The AAPS journal. vol 7. issue 4. 2006-08-16. PMID:16594640. |
the approaches for mathematical modeling of signaling pathways activated by 5-ht receptors are described briefly in the context of ongoing work on detailed biochemical models of 5-ht2a, and combined 5-ht2a/5-ht1a, receptor-mediated activation of the mapk 1,2 pathway. |
2006-08-16 |
2023-08-12 |
Not clear |
| Sharon Rosenzweig-Lipson, Jean Zhang, Hossein Mazandarani, Boyd L Harrison, Annmarie Sabb, Joan Sabalski, Gary Stack, Greg Welmaker, James E Barrett, John Dunlo. Antiobesity-like effects of the 5-HT2C receptor agonist WAY-161503. Brain research. vol 1073-1074. 2006-07-19. PMID:16430874. |
relative to 5-ht2c receptor binding, way-161503 was approximately 6-fold less potent at human 5-ht2a receptors ([125i]doi) with a derived ki value of 18 nm and 20-fold less potent at human 5-ht2b receptors ([3h]5-ht) with a derived ki value of 60 nm. |
2006-07-19 |
2023-08-12 |
mouse |
| Sharon Rosenzweig-Lipson, Jean Zhang, Hossein Mazandarani, Boyd L Harrison, Annmarie Sabb, Joan Sabalski, Gary Stack, Greg Welmaker, James E Barrett, John Dunlo. Antiobesity-like effects of the 5-HT2C receptor agonist WAY-161503. Brain research. vol 1073-1074. 2006-07-19. PMID:16430874. |
in ip studies, way-161503 was a weak 5-ht(2a) partial agonist (ec50, 802 nm) yet potently stimulated calcium mobilization (ec50, 7 nm) in 5-ht2a receptor-expressing cells. |
2006-07-19 |
2023-08-12 |
mouse |
| Ivo F Brandes, Edward J Zuperku, Astrid G Stucke, Danica Jakovcevic, Francis A Hopp, Eckehard A E Stut. Serotonergic modulation of inspiratory hypoglossal motoneurons in decerebrate dogs. Journal of neurophysiology. vol 95. issue 6. 2006-07-17. PMID:16495364. |
in vitro data suggest that serotonin (5-ht), through the 5-ht2a receptor subtype, plays a key role in controlling the excitability of ihmns. |
2006-07-17 |
2023-08-12 |
Not clear |
| Ivo F Brandes, Edward J Zuperku, Astrid G Stucke, Danica Jakovcevic, Francis A Hopp, Eckehard A E Stut. Serotonergic modulation of inspiratory hypoglossal motoneurons in decerebrate dogs. Journal of neurophysiology. vol 95. issue 6. 2006-07-17. PMID:16495364. |
we hypothesized that in vivo 5-ht modulates ihmns activity through the 5-ht2a receptor subtype. |
2006-07-17 |
2023-08-12 |
Not clear |
| Ivo F Brandes, Edward J Zuperku, Astrid G Stucke, Danica Jakovcevic, Francis A Hopp, Eckehard A E Stut. Serotonergic modulation of inspiratory hypoglossal motoneurons in decerebrate dogs. Journal of neurophysiology. vol 95. issue 6. 2006-07-17. PMID:16495364. |
to test this hypothesis, we used multibarrel micropipettes for extracellular single neuron recording and pressure picoejection of 5-ht or ketanserin, a selective 5-ht2a receptor subtype antagonist, onto single ihmns in decerebrate, vagotomized, paralyzed, and mechanically ventilated dogs. |
2006-07-17 |
2023-08-12 |
Not clear |
| Ivo F Brandes, Edward J Zuperku, Astrid G Stucke, Danica Jakovcevic, Francis A Hopp, Eckehard A E Stut. Serotonergic modulation of inspiratory hypoglossal motoneurons in decerebrate dogs. Journal of neurophysiology. vol 95. issue 6. 2006-07-17. PMID:16495364. |
these results confirm our hypothesis that in vivo 5-ht is a potent modulator of ihmn activity through the 5-ht2a receptor subtype. |
2006-07-17 |
2023-08-12 |
Not clear |
| Miyuki Yamamoto, Jing Ji Jin, Zhihong Wu, Michiko Abe, Yasuharu Tabara, Tokihisa Nagai, Eiji Yamasaki, Michiya Igase, Katsuhiko Kohara, Tetsuro Miki, Jun Nakur. Interaction between serotonin 2A receptor and endothelin-1 variants in association with hypertension in Japanese. Hypertension research : official journal of the Japanese Society of Hypertension. vol 29. issue 4. 2006-07-12. PMID:16778329. |
recently, an association between the t102c functional polymorphism of the serotonin 2a (5-ht2a) receptor gene and hypertension in the uk has been reported. |
2006-07-12 |
2023-08-12 |
human |
| Miyuki Yamamoto, Jing Ji Jin, Zhihong Wu, Michiko Abe, Yasuharu Tabara, Tokihisa Nagai, Eiji Yamasaki, Michiya Igase, Katsuhiko Kohara, Tetsuro Miki, Jun Nakur. Interaction between serotonin 2A receptor and endothelin-1 variants in association with hypertension in Japanese. Hypertension research : official journal of the Japanese Society of Hypertension. vol 29. issue 4. 2006-07-12. PMID:16778329. |
we also investigated the possible interaction between the 5-ht2a t102c polymorphism and the g/t (lys198asn) polymorphism of the endothelin-1 (et-1) gene, based on robust biological evidence for the existence of an interaction between the serotonin and endothelin systems. |
2006-07-12 |
2023-08-12 |
human |
| Hye-Jung Kim, Hyunah Choo, Yong Seo Cho, Hun Yeong Koh, Kyoung Tai No, Ae Nim Pa. Classification of dopamine, serotonin, and dual antagonists by decision trees. Bioorganic & medicinal chemistry. vol 14. issue 8. 2006-07-11. PMID:16387502. |
data set containing 1135 dopamine antagonists (d2, d3, and d4), 1251 serotonin antagonists (5-ht1a, 5-ht2a, and 5-ht2c), and 386 serotonin-dopamine dual antagonists was collected from the mddr database. |
2006-07-11 |
2023-08-12 |
Not clear |
| Elizabeth A Pehek, Christine Nocjar, Bryan L Roth, Tara A Byrd, Omar S Mabrou. Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 2. 2006-07-06. PMID:15999145. |
evidence for the preferential involvement of 5-ht2a serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex. |
2006-07-06 |
2023-08-12 |
rat |
| A G Romano, J L Quinn, R Liu, K D Dave, D Schwab, G Alexander, V J Aloyo, J A Harve. Effect of serotonin depletion on 5-HT2A-mediated learning in the rabbit: evidence for constitutive activity of the 5-HT2A receptor in vivo. Psychopharmacology. vol 184. issue 2. 2006-06-14. PMID:16369834. |
effect of serotonin depletion on 5-ht2a-mediated learning in the rabbit: evidence for constitutive activity of the 5-ht2a receptor in vivo. |
2006-06-14 |
2023-08-12 |
rabbit |
| A G Romano, J L Quinn, R Liu, K D Dave, D Schwab, G Alexander, V J Aloyo, J A Harve. Effect of serotonin depletion on 5-HT2A-mediated learning in the rabbit: evidence for constitutive activity of the 5-HT2A receptor in vivo. Psychopharmacology. vol 184. issue 2. 2006-06-14. PMID:16369834. |
the existence of inverse agonists that retard learning through an action at the 5-ht2a receptor suggests the existence of constitutive activity at that receptor and that depletion of serotonin should have minimal effects on learning. |
2006-06-14 |
2023-08-12 |
rabbit |
| Declan G M Murphy, Eileen Daly, Nicole Schmitz, Fiona Toal, Keiran Murphy, Sarah Curran, Kjell Erlandsson, Jos Eersels, Robert Kerwin, Peter Ell, Michael Travi. Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger's syndrome: an in vivo SPECT study. The American journal of psychiatry. vol 163. issue 5. 2006-06-12. PMID:16648340. |
cortical serotonin 5-ht2a receptor binding and social communication in adults with asperger's syndrome: an in vivo spect study. |
2006-06-12 |
2023-08-12 |
Not clear |
| A Kling, S Rantapää-Dahlqvist, H Stenlund, T Mjörnda. Decreased density of serotonin 5-HT2A receptors in rheumatoid arthritis. Annals of the rheumatic diseases. vol 65. issue 6. 2006-06-12. PMID:16699051. |
decreased density of serotonin 5-ht2a receptors in rheumatoid arthritis. |
2006-06-12 |
2023-08-12 |
Not clear |
| Brigitte Sonier, Madeleine Arseneault, Carole Lavigne, Rodney J Ouellette, Cathy Vaillancour. The 5-HT2A serotoninergic receptor is expressed in the MCF-7 human breast cancer cell line and reveals a mitogenic effect of serotonin. Biochemical and biophysical research communications. vol 343. issue 4. 2006-06-09. PMID:16580628. |
the 5-ht2a serotoninergic receptor is expressed in the mcf-7 human breast cancer cell line and reveals a mitogenic effect of serotonin. |
2006-06-09 |
2023-08-12 |
human |