| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu-Fei Ni, Hao Wang, Qiu-Yan Gu, Fei-Ying Wang, Ying-Jie Wang, Jin-Liang Wang, Bo Jian. Gemfibrozil has antidepressant effects in mice: Involvement of the hippocampal brain-derived neurotrophic factor system. Journal of psychopharmacology (Oxford, England). vol 32. issue 4. 2019-10-11. PMID:29534628. |
gemfibrozil has antidepressant effects in mice: involvement of the hippocampal brain-derived neurotrophic factor system. |
2019-10-11 |
2023-08-13 |
mouse |
| Marlena Wosiski-Kuhn, Mihail Bota, Christina A Snider, Steven P Wilson, Kannan U Venkataraju, Pavel Osten, Alexis M Stranaha. Hippocampal brain-derived neurotrophic factor determines recruitment of anatomically connected networks after stress in diabetic mice. Hippocampus. vol 28. issue 12. 2019-10-04. PMID:30098276. |
hippocampal brain-derived neurotrophic factor determines recruitment of anatomically connected networks after stress in diabetic mice. |
2019-10-04 |
2023-08-13 |
mouse |
| Zhe Li, Xuezhao Cao, Hong Ma, Yong Cui, Xiaoqian Li, Na Wang, Yongjian Zho. Surgical Trauma Exacerbates Cognitive Deficits and Neuroinflammation in Aged Rats: The Role of CX3CL1-CX3CR1 Signaling. Journal of neuropathology and experimental neurology. vol 77. issue 8. 2019-10-03. PMID:29939299. |
hippocampal interleukin-1β, cx3cl1, cx3cr1, brain derived neurotrophic factor (bdnf), ionized calcium-binding adapter molecule 1 (iba-1), and arginase-1 (arg1) levels were measured. |
2019-10-03 |
2023-08-13 |
rat |
| Fu-Sheng Ding, Xiang Cheng, Tong Zhao, Yong-Qi Zhao, Guang-Bo Zhang, Hai-Tao Wu, Ling-Ling Zhu, Kui-Wu W. [Intermittent hypoxic preconditioning relieves fear and anxiety behavior in post-traumatic stress model mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 71. issue 4. 2019-09-26. PMID:31440750. |
the levels of fear and anxiety were valued by the open field, the elevated plus maze (epm) and the fear conditioning tests; the level of spatial memory was valued by y maze test; the number of fos positive neurons in hippocampus, amygdala and medial prefrontal cortex was valued by immunohistochemical staining; and the protein expressions of hypoxia inducible factor-1α (hif-1α), vascular endothelial growth factor (vegf) and brain derived neurotrophic factor (bdnf) in these brain area were valued by western blot. |
2019-09-26 |
2023-08-13 |
mouse |
| Ali Ahmadalipour, Shahrbanoo Ghodrati-Jaldbakhan, Seyed Afshin Samaei, Ali Rashidy-Pou. Deleterious effects of prenatal exposure to morphine on the spatial learning and hippocampal BDNF and long-term potentiation in juvenile rats: Beneficial influences of postnatal treadmill exercise and enriched environment. Neurobiology of learning and memory. vol 147. 2019-09-09. PMID:29175674. |
the present study investigated the effects of postnatal exercise and enriched environment (ee) on alterations in water maze learning and hippocampal long-term potentiation (ltp) and brain derived neurotrophic factor (bdnf) levels induced by exposure to morphine during prenatal period in rats. |
2019-09-09 |
2023-08-13 |
rat |
| Yan Fang, Naiyi Du, Longyan Xing, Yali Duo, Lei Zhen. Evaluation of hippocampal volume and serum brain-derived neurotrophic factor as potential diagnostic markers of conversion from amnestic mild cognitive impairment to Alzheimer disease: A STROBE-compliant article. Medicine. vol 98. issue 30. 2019-08-13. PMID:31348306. |
evaluation of hippocampal volume and serum brain-derived neurotrophic factor as potential diagnostic markers of conversion from amnestic mild cognitive impairment to alzheimer disease: a strobe-compliant article. |
2019-08-13 |
2023-08-13 |
human |
| Mehdi Khodamoradi, Hamed Ghazvini, Saeed Esmaeili-Mahani, Kaveh Shahveisi, Vahid Farnia, Hossein Zhaleh, Nasrin Abdoli, Zeinab Akbarnejad, Hakimeh Saadati, Vahid Sheiban. Genistein attenuates seizure-induced hippocampal brain-derived neurotrophic factor overexpression in ovariectomized rats. Journal of chemical neuroanatomy. vol 89. 2019-08-02. PMID:29524607. |
genistein attenuates seizure-induced hippocampal brain-derived neurotrophic factor overexpression in ovariectomized rats. |
2019-08-02 |
2023-08-13 |
rat |
| Mira Han, Jae-Jun Ban, Jung-Soo Bae, Chang-Yup Shin, Dong Hun Lee, Jin Ho Chun. UV irradiation to mouse skin decreases hippocampal neurogenesis and synaptic protein expression via HPA axis activation. Scientific reports. vol 7. issue 1. 2019-07-09. PMID:29138442. |
moreover, we observed that uv irradiation to the skin down-regulated brain-derived neurotrophic factor expression and erk signaling in the hippocampus, which are known to modulate neurogenesis and synaptic plasticity. |
2019-07-09 |
2023-08-13 |
mouse |
| Rong-Rong Zhang, Ze-Xin Lin, Xin-Yi Lu, Xue Xia, Ren-Wang Jiang, Qu-Bo Che. CGY-1, a biflavonoid isolated from cardiocrinum giganteum seeds, improves memory deficits by modulating the cholinergic system in scopolamine-treated mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 111. 2019-06-17. PMID:30594789. |
furthermore, qpcr and western blot results revealed that the expressions of neurotrophic factors, brain-derived neurotrophic factor and nerve growth factor were upregulated in the hippocampus after cgy-1 treatment. |
2019-06-17 |
2023-08-13 |
mouse |
| Zahra Jahangiri, Zahra Gholamnezhad, Mahmoud Hossein. Neuroprotective effects of exercise in rodent models of memory deficit and Alzheimer's. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30443769. |
neuroperotective effects of exercise on the hippocampus seem to be increasing in immediate-early gene c-fos expression in dentate gyrus; enhancing the wnt3 expression and inhibiting glycogen synthase kinase-3β expression; increasing the 5-bro-mo-2'-deoxyridine-positive and doublecortin-positive cells (dentate gyrus); increasing the level of astrocytes glial fibrillary acidic protein and decrease in s100b protein, increasing in blood brain barrier integrity; prevention of oxidative stress injury, inducing morphological changes in astrocytes in the stratum radiatum of cornu ammonis 1(ca1) area; increase in cell proliferation and suppress apoptosis in dentate gyrus; increase in brain-derived neurotrophic factor and tropomyosin receptor kinase b expressions; enhancing the glycogen levels and normalizing the monocarboxylate transporter 2 expression. |
2019-06-06 |
2023-08-13 |
Not clear |
| Hatice Asli Bedel, Ceren Kencebay Manas, Gül Özbey, Coşkun Ust. The antidepressant-like activity of ellagic acid and its effect on hippocampal brain derived neurotrophic factor levels in mouse depression models. Natural product research. vol 32. issue 24. 2019-05-15. PMID:29017372. |
the antidepressant-like activity of ellagic acid and its effect on hippocampal brain derived neurotrophic factor levels in mouse depression models. |
2019-05-15 |
2023-08-13 |
mouse |
| Dong Wook Lim, Min Young Um, Taewon Han, Jaekwang Lee, Yun Tai Kim, Suengmok Cho, In-Ho Kim, Daeseok Han, Changho Le. Standardized Citrus unshiu peel extract ameliorates dexamethasone-induced neurotoxicity and depressive-like behaviors in mice. Metabolic brain disease. vol 33. issue 6. 2019-05-13. PMID:30229385. |
additionally, repeated dex injection markedly decreased brain derived neurotrophic factor (bdnf) level, tropomyosin receptor kinase b (trkb), and cyclic amp-response element-binding protein (creb), while scp treatment improved these levels in the cerebral cortex and hippocampus regions. |
2019-05-13 |
2023-08-13 |
mouse |
| Sherin Jacob, Thangarajan Sumath. Extenuation of in utero toxic effects of MeHg in the developing neurons by Fisetin via modulating the expression of synaptic transmission and plasticity regulators in hippocampus of the rat offspring. Chemico-biological interactions. vol 305. 2019-05-10. PMID:30890323. |
fisetin also prevented mehg exposure induced downregulation of brain derived neurotrophic factor (bdnf), glial-cell derived neurotrophic factor (gdnf) protein expressions and hampered reactive astrogliosis in the hippocampus of f |
2019-05-10 |
2023-08-13 |
rat |
| Jiucui Tong, Zhiming Zhou, Weiwei Qi, Siyan Jiang, Bin Yang, Zhengling Zhong, Yuanwei Jia, Xuyi Li, Lei Xiong, Liuwang Ni. Antidepressant effect of helicid in chronic unpredictable mild stress model in rats. International immunopharmacology. vol 67. 2019-05-03. PMID:30530165. |
helicid also reversed cums-induced decreases of 5-ht1a receptor expression and promoted brain derived neurotrophic factor (bdnf) expression in the hippocampus the significant reversal of depressive-like behaviors by helicid is similar to that achieved by fluoxetine. |
2019-05-03 |
2023-08-13 |
rat |
| C W Bird, B C Baculis, J J Mayfield, G J Chavez, T Ontiveros, D J Paine, A J Marks, A L Gonzales, D Ron, C F Valenzuel. The brain-derived neurotrophic factor VAL68MET polymorphism modulates how developmental ethanol exposure impacts the hippocampus. Genes, brain, and behavior. vol 18. issue 3. 2019-05-01. PMID:29691979. |
the brain-derived neurotrophic factor val68met polymorphism modulates how developmental ethanol exposure impacts the hippocampus. |
2019-05-01 |
2023-08-13 |
mouse |
| Qiuping Zhong, Hui Yu, Chang Huang, Jiahong Zhong, Haitao Wang, Jiangping Xu, Yufang Chen. FCPR16, a novel phosphodiesterase 4 inhibitor, produces an antidepressant-like effect in mice exposed to chronic unpredictable mild stress. Progress in neuro-psychopharmacology & biological psychiatry. vol 90. 2019-04-22. PMID:30391306. |
simultaneously, data indicated that fcpr16 enhanced the levels of several proteins, including camp, brain derived neurotrophic factor, exchange protein directly activated by camp 2 (epac-2), synapsin1, postsynaptic density protein 95, phosphorylated camp response element binding protein and extracellular regulated protein kinases 1/2, which were downregulated by cums in both the cerebral cortex and hippocampus. |
2019-04-22 |
2023-08-13 |
mouse |
| Jian Liu, Han-Xiao Zhu, Wan-Li Fu, Xin-Wei Xu, Jun-Zhe Yang, Dan Dai, Yun L. Downregulated hippocampal expression of brain derived neurotrophic factor and tyrosine kinase B in a rat model of comorbid epilepsy and depression. Neurological research. vol 41. issue 5. 2019-04-18. PMID:30741614. |
downregulated hippocampal expression of brain derived neurotrophic factor and tyrosine kinase b in a rat model of comorbid epilepsy and depression. |
2019-04-18 |
2023-08-13 |
rat |
| O Giotako. Is impulsivity in part a lithium deficiency state? Psychiatrike = Psychiatriki. vol 29. issue 3. 2019-04-15. PMID:30605431. |
in humans, lithium treatment has been associated with humoral and structural evidence of neuroprotection, such as increased expression of antiapoptotic genes, inhibition of cellular oxidative stress, synthesis of brain-derived neurotrophic factor, cortical thickening, increased grey matter density, and hippocampal enlargement. |
2019-04-15 |
2023-08-13 |
Not clear |
| Mei-Hsin Hsu, Yu-Chieh Chen, Jiunn-Ming Sheen, Shih-Wen Li, Li-Tung Huan. Melatonin prevented spatial deficits and increases in brain asymmetric dimethylarginine in young bile duct ligation rats. Neuroreport. vol 29. issue 7. 2019-04-09. PMID:29384993. |
in addition, melatonin maintained brain-derived neurotrophic factor in the dorsal hippocampus at a level comparable with controls. |
2019-04-09 |
2023-08-13 |
rat |
| Luofang Peng, Maoen Zhu, Yong Yang, Yingqi Weng, Wangyuan Zou, Xiaoyan Zhu, Qulian Guo, Tao Zhon. Neonatal Lipopolysaccharide Challenge Induces Long-lasting Spatial Cognitive Impairment and Dysregulation of Hippocampal Histone Acetylation in Mice. Neuroscience. vol 398. 2019-03-18. PMID:30543856. |
subsequently, we assessed histone acetylation and immediate-early response gene expression (c-fos and brain-derived neurotrophic factor) in the hippocampus in response to mwm acquisition training. |
2019-03-18 |
2023-08-13 |
mouse |