| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rong Gao, Guomin Li, Runhua Yang, Hongmei Yuan, Shaogang Zhan. Hippocampal β2‑microglobulin mediates sepsis‑induced cognitive impairment. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29620245. |
the data revealed that clp induced anxiety‑like behavior and impaired hippocampal‑dependent contextual memory in wild‑type mice, which was accompanied by hippocampal microglial activation, increased level of interleukin‑1β, and decreased concentrations of brain derived neurotrophic factor and postsynaptic density protein 95. |
2018-09-26 |
2023-08-13 |
mouse |
| Mostofa Jamal, Asuka Ito, Naoko Tanaka, Takanori Miki, Ayaka Takakura, Shingo Suzuki, Kiyoshi Ameno, Hiroshi Kinoshit. The Role of Apolipoprotein E and Ethanol Exposure in Age-Related Changes in Choline Acetyltransferase and Brain-Derived Neurotrophic Factor Expression in the Mouse Hippocampus. Journal of molecular neuroscience : MN. vol 65. issue 1. 2018-09-26. PMID:29717403. |
the role of apolipoprotein e and ethanol exposure in age-related changes in choline acetyltransferase and brain-derived neurotrophic factor expression in the mouse hippocampus. |
2018-09-26 |
2023-08-13 |
mouse |
| Sung Woo Park, Mi Kyoung Seo, Jung Goo Lee, Le Thi Hien, Young Hoon Ki. Effects of maternal separation and antidepressant drug on epigenetic regulation of the brain-derived neurotrophic factor exon I promoter in the adult rat hippocampus. Psychiatry and clinical neurosciences. vol 72. issue 4. 2018-09-13. PMID:28990703. |
effects of maternal separation and antidepressant drug on epigenetic regulation of the brain-derived neurotrophic factor exon i promoter in the adult rat hippocampus. |
2018-09-13 |
2023-08-13 |
rat |
| Michelle E Schober, Daniela F Requena, Christopher K Rodesc. EPO improved neurologic outcome in rat pups late after traumatic brain injury. Brain & development. vol 40. issue 5. 2018-09-05. PMID:29429559. |
we hypothesized that erythropoietin would increase brain derived neurotrophic factor and improve long-term object recognition in rat pups after controlled cortical impact, associated with increased neuronal fraction in the hippocampus. |
2018-09-05 |
2023-08-13 |
rat |
| Isabel Carreras, Nurgul Aytan, Tiffany Mellott, Ji-Kyung Choi, Margaret Lehar, Leah Crabtree, Kimberly Leite-Morris, Bruce G Jenkins, Jan Krzysztof Blusztajn, Alpaslan Dedeogl. Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease. Brain research. vol 1681. 2018-08-15. PMID:29277710. |
we also observed that gwi model was sexually dimorphic on some measures: males had increased while females had decreased protein levels of the acetylcholine-synthesizing enzyme, choline acetyltransferase, in the septum and hippocampus and decreased levels of the receptor for brain-derived neurotrophic factor, trkb140, in the hippocampus. |
2018-08-15 |
2023-08-13 |
mouse |
| Ge Wang, Fen He, Yunlong Xu, Yuwei Zhang, Xiao Wang, Chunhua Zhou, Yihong Huang, Juntao Zo. Immunopotentiator Thymosin Alpha-1 Promotes Neurogenesis and Cognition in the Developing Mouse via a Systemic Th1 Bias. Neuroscience bulletin. vol 33. issue 6. 2018-07-24. PMID:28780644. |
the numbers of 5-bromodeoxyuridine (brdu)+, nestin+, t-box transcription factor 2 (tbr2)+, brdu+/doublecortin (dcx)+, brdu+/ionized calcium-binding adaptor molecule 1 (iba1)+, and brdu+/neuronal nuclei (neun)+ cells in the hippocampus were increased in the ta1 group, accompanied by increased interleukin-4 (il-4), interferon-gamma, brain-derived neurotrophic factor, nerve growth factor, and insulin-like growth factor-1 as well as decreased il-6 and tumor necrosis factor-α. |
2018-07-24 |
2023-08-13 |
mouse |
| Doyun Kim, Sena Chung, Seung-Hyun Lee, Se-Young Choi, Soung-Min Kim, JaeHyung Koo, Jong-Ho Lee, Jeong Won Jahn. Decreased hippocampal brain-derived neurotrophic factor and impaired cognitive function by hypoglossal nerve transection in rats. Journal of cellular and molecular medicine. vol 21. issue 12. 2018-07-18. PMID:28767193. |
decreased hippocampal brain-derived neurotrophic factor and impaired cognitive function by hypoglossal nerve transection in rats. |
2018-07-18 |
2023-08-13 |
rat |
| Roger Hudson, Yan Zhou, Francesco Ler. The combination of escitalopram and aripiprazole: Investigation of psychomotor effects in rats. Journal of psychopharmacology (Oxford, England). vol 31. issue 12. 2018-07-11. PMID:29069975. |
at the conclusion of behavioral testing, mrnas of two genes involved in reward processes were quantified: hypothalamic pro-opiomelanocortin and hippocampal brain-derived neurotrophic factor. |
2018-07-11 |
2023-08-13 |
rat |
| Patricia B de la Tremblaye, Simon M Benoit, Sarah Schock, Hélène Plamondo. CRHR1 exacerbates the glial inflammatory response and alters BDNF/TrkB/pCREB signaling in a rat model of global cerebral ischemia: implications for neuroprotection and cognitive recovery. Progress in neuro-psychopharmacology & biological psychiatry. vol 79. issue Pt B. 2018-06-12. PMID:28647536. |
thirty days post ischemia, brain derived neurotrophic factor (bdnf) and tropomyosin receptor kinase b (trkb) receptor expression, hippocampal neuronal death and inflammation were determined by analyzing immunoreactivity (ir) of neuron-specific nuclear protein (neun), microglia (iba1, ionized calcium binding adaptor molecule 1), astrocytes (gfap, glial fibrillary acidic protein) and tnfα (tumor necrosis factor alpha) a pro-inflammatory cytokine. |
2018-06-12 |
2023-08-13 |
rat |
| Ying-Li Zhu, Lin-Yuan Wang, Cheng-Long Wang, Dan-Ping Zhao, Sha Wang, Wen-Ting Fei, Jian-Jun Zhan. [Investigation of effects of albiflorin and paeoniflorin on hippocampal BDNF and NO in chronic restraint stress rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 41. issue 22. 2018-05-30. PMID:28933095. |
furthermore, the levels of brain derived neurotrophic factor (bdnf) in hippocampus were detected by elisa. |
2018-05-30 |
2023-08-13 |
rat |
| Atsushi Sawamoto, Satoshi Okuyama, Yoshiaki Amakura, Morio Yoshimura, Takashi Yamada, Hidehiko Yokogoshi, Mitsunari Nakajima, Yoshiko Furukaw. 3,5,6,7,8,3',4'-Heptamethoxyflavone Ameliorates Depressive-Like Behavior and Hippocampal Neurochemical Changes in Chronic Unpredictable Mild Stressed Mice by Regulating the Brain-Derived Neurotrophic Factor: Requirement for ERK Activation. International journal of molecular sciences. vol 18. issue 10. 2018-05-30. PMID:29023414. |
3,5,6,7,8,3',4'-heptamethoxyflavone ameliorates depressive-like behavior and hippocampal neurochemical changes in chronic unpredictable mild stressed mice by regulating the brain-derived neurotrophic factor: requirement for erk activation. |
2018-05-30 |
2023-08-13 |
mouse |
| Setayesh R Tasbihgou, Mina Netkova, Alain F Kalmar, Janine Doorduin, Michel M R F Struys, Regien G Schoemaker, Anthony R Absalo. Brain changes due to hypoxia during light anaesthesia can be prevented by deepening anaesthesia; a study in rats. PloS one. vol 13. issue 2. 2018-05-23. PMID:29451906. |
after another 4 days, the animals were sacrificed for later immunohistochemical analyses of neurogenesis/neuroplasticity (doublecortin; dcx), brain derived neurotrophic factor (bdnf) expression and neuroinflammation (ionized calcium-binding adaptor protein-1; iba-1) in hippocampal and piriform cortex slices. |
2018-05-23 |
2023-08-13 |
rat |
| Florian Reichmann, Vanessa Wegerer, Piyush Jain, Raphaela Mayerhofer, Ahmed M Hassan, Esther E Fröhlich, Elisabeth Bock, Elisabeth Pritz, Herbert Herzog, Peter Holzer, Gerd Leitinge. Environmental enrichment induces behavioural disturbances in neuropeptide Y knockout mice. Scientific reports. vol 6. 2018-05-22. PMID:27305846. |
in addition, npy deletion altered the preference of ee items, and ee-housed npy ko mice responded to stress with exaggerated hyperthermia, displayed impaired spatial memory, had higher hippocampal brain-derived neurotrophic factor mrna levels and altered hippocampal synaptic plasticity, effects which were not seen in wt mice. |
2018-05-22 |
2023-08-13 |
mouse |
| Ami Bhakta, Kartheek Gavini, Euitaek Yang, Lani Lyman-Henley, Kodeeswaran Parameshwara. Chronic traumatic stress impairs memory in mice: Potential roles of acetylcholine, neuroinflammation and corticotropin releasing factor expression in the hippocampus. Behavioural brain research. vol 335. 2018-05-22. PMID:28797603. |
there were no changes in brain derived neurotrophic factor (bdnf) or nerve growth factor (ngf) levels in the hippocampus of stressed mice. |
2018-05-22 |
2023-08-13 |
mouse |
| Anjali Chawla, Zachary A Cordner, Gretha Boersma, Timothy H Mora. Cognitive impairment and gene expression alterations in a rodent model of binge eating disorder. Physiology & behavior. vol 180. 2018-05-14. PMID:28821448. |
aberrant gene expression of brain derived neurotrophic factor (bdnf) and tropomyosin receptor kinase b (trkb) in the hippocampus (hpc)-prefrontal cortex (pfc) network was observed in bep rats. |
2018-05-14 |
2023-08-13 |
rat |
| Yuan Liu, Chenhui Li, Jing Wang, Yinquan Fang, Hao Sun, Xia Tao, Xin-Fu Zhou, Hong Lia. Nafamostat Mesilate Improves Neurological Outcome and Axonal Regeneration after Stroke in Rats. Molecular neurobiology. vol 54. issue 6. 2018-05-10. PMID:27335029. |
the expression of brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3 was increased in the contralateral sensorimotor cortex and ipsilateral hippocampus by the administration of nm. |
2018-05-10 |
2023-08-13 |
rat |
| Imran Jamal, Vipendra Kumar, Naman Vatsa, Brijesh Kumar Singh, Shashi Shekhar, Ankit Sharma, Nihar Ranjan Jan. Environmental Enrichment Improves Behavioral Abnormalities in a Mouse Model of Angelman Syndrome. Molecular neurobiology. vol 54. issue 7. 2018-05-10. PMID:27581300. |
biochemical analysis further revealed restoration of altered levels of brain-derived neurotrophic factor, glucocorticoid receptor, and phoshphorylated calcium/calmodulin-dependent protein kinase iiα in the hippocampus of as mice maintained in the enriched environment. |
2018-05-10 |
2023-08-13 |
mouse |
| Nesreen Nabil Omar, Reham Fathy Tas. Fluoxetine coupled with zinc in a chronic mild stress model of depression: Providing a reservoir for optimum zinc signaling and neuronal remodeling. Pharmacology, biochemistry, and behavior. vol 160. 2018-05-09. PMID:28801265. |
the aim of the present study is to examine whether depression-induced changes in protein levels and mrna levels of nuclear factor-erythroid 2-related factor 2 (nrf2), mts, antioxidant defensive enzyme heme oxygenase (ho-1), zinc-specific receptor gpr39 and brain derived neurotrophic factor (bdnf) in the hippocampus can be reversed by fluoxetine treatment, zinc supplementation or a combination of the two. |
2018-05-09 |
2023-08-13 |
Not clear |
| Caroline O'Hagan, Jia V Li, Julian R Marchesi, Sue Plummer, Iveta Garaiova, Mark A Goo. Long-term multi-species Lactobacillus and Bifidobacterium dietary supplement enhances memory and changes regional brain metabolites in middle-aged rats. Neurobiology of learning and memory. vol 144. 2018-05-08. PMID:28602659. |
previous work has shown that dietary supplements with multi-species live microorganisms can influence brain function, including induction of hippocampal synaptic plasticity and production of brain derived neurotrophic factor, in both young and aged rodents. |
2018-05-08 |
2023-08-13 |
rat |
| Danfeng Xu, Di Lian, Jing Wu, Ying Liu, Mingjie Zhu, Jiaming Sun, Dake He, Ling L. Brain-derived neurotrophic factor reduces inflammation and hippocampal apoptosis in experimental Streptococcus pneumoniae meningitis. Journal of neuroinflammation. vol 14. issue 1. 2018-05-03. PMID:28778220. |
brain-derived neurotrophic factor reduces inflammation and hippocampal apoptosis in experimental streptococcus pneumoniae meningitis. |
2018-05-03 |
2023-08-13 |
Not clear |