All Relations between brain derived neurotrophic factor and hippocampus

Publication Sentence Publish Date Extraction Date Species
Irit Gil-Ad, Moshe Portnoy, Igor Tarasenko, Miri Bidder, Maria Kramer, Michal Taler, Abraham Weizma. A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 3. 2014-11-25. PMID:24389121. moreover, pgw5, but not olanzapine, attenuated phencyclidine (pcp)-induced deficits of social preference in mice and promoted the expression of brain derived neurotrophic factor (bdnf) in the hippocampus and the frontal cortex and glutamic acid decarboxylase (gad67) in the hippocampus. 2014-11-25 2023-08-12 mouse
Jesper Krogh, Egill Rostrup, Carsten Thomsen, Betina Elfving, Poul Videbech, Merete Nordentof. The effect of exercise on hippocampal volume and neurotrophines in patients with major depression--a randomized clinical trial. Journal of affective disorders. vol 165. 2014-11-24. PMID:24882173. the effect of exercise on hippocampal volume is potentially mediated by brain derived neurotrophic factor (bdnf), vascular endothelial growth factor (vegf), and insulin like growth factor 1 (igf-1). 2014-11-24 2023-08-13 Not clear
Ahmed M Hassan, Piyush Jain, Florian Reichmann, Raphaela Mayerhofer, Aitak Farzi, Rufina Schuligoi, Peter Holze. Repeated predictable stress causes resilience against colitis-induced behavioral changes in mice. Frontiers in behavioral neuroscience. vol 8. 2014-11-21. PMID:25414650. dss-induced colitis was associated with an increase in circulating neuropeptide y (npy), a rise in the hypothalamic expression of cyclooxygenase-2 mrna and a decrease in the hippocampal expression of npy mrna, brain-derived neurotrophic factor mrna and mineralocorticoid receptor mrna. 2014-11-21 2023-08-13 mouse
H F Sakr, K I Khalil, A M Hussein, M S A Zaki, R A Eid, M Alkhatee. Effect of dehydroepiandrosterone (DHEA) on memory and brain derived neurotrophic factor (BDNF) in a rat model of vascular dementia. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 65. issue 1. 2014-11-13. PMID:24622829. furthermore, the expression of brain derived neurotrophic factor (bdnf) in the hippocampus was determined. 2014-11-13 2023-08-12 rat
Rosalia Crupi, Irene Paterniti, Akbar Ahmad, Michela Campolo, Emanuela Esposito, Salvatore Cuzzocre. Effects of palmitoylethanolamide and luteolin in an animal model of anxiety/depression. CNS & neurological disorders drug targets. vol 12. issue 7. 2014-11-12. PMID:23844686. adult hippocampal neurogenesis and neuroplasticity were evaluated by immunohistochemical techniques; brain-derived neurotrophic factor and apoptotic protein (bax and bcl2) expression were studied by immunostaining and western blot analysis. 2014-11-12 2023-08-12 mouse
Dexiang Liu, Kai Xie, Xudong Yang, Jianhua Gu, Li Ge, Xueer Wang, Zhen Wan. Resveratrol reverses the effects of chronic unpredictable mild stress on behavior, serum corticosterone levels and BDNF expression in rats. Behavioural brain research. vol 264. 2014-11-05. PMID:24503118. the present study attempts to explore the mechanisms underlying the antidepressant-like action of resveratrol by measuring serum corticosterone levels and the content of brain derived neurotrophic factor (bdnf) in the hippocampus and amygdala of rats exposed to the chronic unpredictable mild stress (cums). 2014-11-05 2023-08-12 rat
Hui Yao, Li-Jia Gu, Jian-You Gu. [Study on effect of astragali radix polysaccharides in improving learning and memory functions in aged rats and its mechanism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 39. issue 11. 2014-10-28. PMID:25272845. the western-blot method was used to observe the levels of relevant neural plasticity protein n-methyl-d-aspartate receptor (nmda receptor) in hippocampus, calcium/calmodulin dependent protein kinase ii (camk ii), protein kinase (pka), the phosphorylation level of camp response element binding protein (creb) and the protein expression of brain derived neurotrophic factor(bdnf). 2014-10-28 2023-08-13 rat
Zhaohui Zhang, Pengge Fei, Junlin Mu, Wenqiang Li, Jinggui Son. Hippocampal expression of aryl hydrocarbon receptor nuclear translocator 2 and neuronal PAS domain protein 4 in a rat model of depression. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 35. issue 2. 2014-10-21. PMID:23861074. the transcription factors aryl hydrocarbon receptor nuclear translocator 2 (arnt2) and neuronal pas domain protein 4 (npas4) may influence emotion and cognitive function by regulating brain-derived neurotrophic factor expression in the hippocampus. 2014-10-21 2023-08-12 rat
Daniela Puzzo, Carla Loreto, Salvatore Giunta, Giuseppe Musumeci, Giuseppina Frasca, Maria Vittoria Podda, Ottavio Arancio, Agostino Palmer. Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice. Neurobiology of aging. vol 35. issue 3. 2014-09-29. PMID:24112792. we demonstrated that chronic intraperitoneal injection of sildenafil (3 mg/kg for 3 weeks) decreased terminal deoxyuridine triphosphate nick end labeling-positive cells in the ca1 hippocampal area of 26-30-month-old mice, downregulating the proapoptotic proteins, caspase-3 and b-cell lymphoma 2-associated x, and increasing antiapoptotic molecules such as b-cell lymphoma protein-2 and brain-derived neurotrophic factor. 2014-09-29 2023-08-12 mouse
Yi Shu, Hong Zhang, Tao Kang, Jun-jian Zhang, Ying Yang, Hui Liu, Lei Zhan. PI3K/Akt signal pathway involved in the cognitive impairment caused by chronic cerebral hypoperfusion in rats. PloS one. vol 8. issue 12. 2014-09-19. PMID:24339978. in previous studies we found that learning capacity and memory were gradually impaired with cch, which altered the expression of synaptophysin, microtubule associated protein-2, growth associated protein-43, brain-derived neurotrophic factor, nerve growth factor, n-methyl-d-aspartate receptor subunit 1, camp response element-binding protein and tau hyperphosphorylation in the hippocampus. 2014-09-19 2023-08-12 rat
Zeeba D Kabir, Aaron C Katzman, Barry E Kosofsk. Molecular mechanisms mediating a deficit in recall of fear extinction in adult mice exposed to cocaine in utero. PloS one. vol 8. issue 12. 2014-09-16. PMID:24358339. while we observed no change in the constitutive expression of brain derived neurotrophic factor (bdnf) protein and mrna in the mpfc and hippocampus of adult pcoc mice, we observed blunted bdnf signaling in the mpfc of adult pcoc mice after fear extinction compared to the control animals. 2014-09-16 2023-08-12 mouse
Joan M Jasien, Caitlin M Daimon, Rui Wang, Bruce K Shapiro, Bronwen Martin, Stuart Maudsle. The effects of aging on the BTBR mouse model of autism spectrum disorder. Frontiers in aging neuroscience. vol 6. 2014-09-16. PMID:25225482. unbiased proteomic analysis of hippocampal and cortical tissue of btbr mice compared to age-matched wild-type controls revealed a significant decrease in brain derived neurotrophic factor and significant increases in multiple synaptic markers (spinophilin, synapsin i, psd 95, neun), as well as distinct changes in functional pathways related to these proteins, including "neural synaptic plasticity regulation" and "neurotransmitter secretion regulation." 2014-09-16 2023-08-13 mouse
Sung Jin Kwon, Jeongsook Park, So Yun Park, Kwang Seop Song, Sun Tae Jung, So Bong Jung, Ik Ryeul Park, Wan Sung Choi, Sun Ok Kwo. Low-intensity treadmill exercise and/or bright light promote neurogenesis in adult rat brain. Neural regeneration research. vol 8. issue 10. 2014-09-10. PMID:25206384. the purpose of this study was to investigate the effects of low-intensity exercise and bright light exposure on neurogenesis and brain-derived neurotrophic factor expression in adult rat hippocampus. 2014-09-10 2023-08-13 rat
Sung Jin Kwon, Jeongsook Park, So Yun Park, Kwang Seop Song, Sun Tae Jung, So Bong Jung, Ik Ryeul Park, Wan Sung Choi, Sun Ok Kwo. Low-intensity treadmill exercise and/or bright light promote neurogenesis in adult rat brain. Neural regeneration research. vol 8. issue 10. 2014-09-10. PMID:25206384. moreover, the expression level of brain-derived neurotrophic factor in the rat hippocampal dentate gyrus was significantly higher in the exercise group and light group than that in the control group. 2014-09-10 2023-08-13 rat
Lina Zhang, Weiwei Dai, Xueli Zhang, Zhangbin Gong, Guoqin Ji. Mannotriose regulates learning and memory signal transduction in the hippocampus. Neural regeneration research. vol 8. issue 32. 2014-09-10. PMID:25206622. thiazolyl blue tetrazolium bromide assay and western blot analysis showed that hippocampal neuron survival rates and protein levels of glucocorti-coid receptor, serum and glucocorticoid-regulated protein kinase, and brain-derived neurotrophic factor were all dramatically decreased after high-concentration corticosterone-induced injury. 2014-09-10 2023-08-13 Not clear
Mohammad Shahandeh, Valiollah Dabidi Roshan, Somayeh Hosseinzadeh, Soleiman Mahjoub, Vaginak Sarkisia. Chronic exercise training versus acute endurance exercise in reducing neurotoxicity in rats exposed to lead acetate. Neural regeneration research. vol 8. issue 8. 2014-09-10. PMID:25206718. 8 weeks of treadmill exercise significantly increased brain-derived neurotrophic factor level in the hippocampus (p = 0.04) and plasma level of total antioxidant capacity of rats exposed to lead acetate (p < 0.001), and significantly decreased plasma level of malondialdehyde (p < 0.001). 2014-09-10 2023-08-13 rat
Mohammad Shahandeh, Valiollah Dabidi Roshan, Somayeh Hosseinzadeh, Soleiman Mahjoub, Vaginak Sarkisia. Chronic exercise training versus acute endurance exercise in reducing neurotoxicity in rats exposed to lead acetate. Neural regeneration research. vol 8. issue 8. 2014-09-10. PMID:25206718. acute exercise only decreased the hippocampal malondialdehyde level (p = 0.09) and increased brain-derived neurotrophic factor level in the hippocampus (p = 0.66). 2014-09-10 2023-08-13 rat
Wanqiang Wu, Xin Wang, Qisen Xiang, Xu Meng, Ye Peng, Na Du, Zhigang Liu, Quancai Sun, Chan Wang, Xuebo Li. Astaxanthin alleviates brain aging in rats by attenuating oxidative stress and increasing BDNF levels. Food & function. vol 5. issue 1. 2014-08-29. PMID:24326685. additionally, ast ameliorated histopathological changes in the hippocampus and restored brain derived neurotrophic factor (bdnf) levels in both the brains and hippocampus of aging rats. 2014-08-29 2023-08-12 rat
A M Robinson, D J Bucc. Physical exercise during pregnancy improves object recognition memory in adult offspring. Neuroscience. vol 256. 2014-08-27. PMID:24157927. exercising during pregnancy has been shown to improve spatial learning and short-term memory, as well as increase brain-derived neurotrophic factor mrna levels and hippocampal cell survival in juvenile offspring. 2014-08-27 2023-08-12 rat
A S R Sierksma, D L A van den Hove, F Pfau, M Philippens, O Bruno, E Fedele, R Ricciarelli, H W M Steinbusch, T Vanmierlo, J Prickaert. Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D. Neuropharmacology. vol 77. 2014-08-26. PMID:24067928. hippocampal brain-derived neurotrophic factor levels and synaptic densities were not different between experimental groups and no effects were observed on hippocampal gsk3β and tau phosphorylation or aβ levels. 2014-08-26 2023-08-12 mouse