All Relations between brain derived neurotrophic factor and hippocampus

Reference Sentence Publish Date Extraction Date Species
Kristina Leuner, Wei Li, Michelle D Amaral, Stephanie Rudolph, Gaston Calfa, Anita M Schuwald, Christian Harteneck, Takafumi Inoue, Lucas Pozzo-Mille. Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca(2+) -permeable TRPC6 channels. Hippocampus vol 23 issue 1 2013 22815087 hyperforin also evoked intracellular ca(2+) transients and depolarizing inward currents sensitive to the trpc channel blocker la(3+) , thus resembling the actions of the neurotrophin brain-derived neurotrophic factor (bdnf) in hippocampal pyramidal neurons. 2013-05-22 2022-01-12 Not clear
Samir Nath, Muznabanu Bachani, Deepti Harshavardhana, Joseph P Steine. Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway. Journal of neurovirology vol 18 issue 6 2013 22886603 epicatechin and egcg targets the brain-derived neurotrophic factor (bdnf) and its precursor probdnf signaling pathways, normalizing both tat-mediated increases in proapoptotic probdnf and concomitant tat-mediated decreases in the mature bdnf protein in hippocampal neurons. 2013-05-07 2022-01-12 Not clear
C Y Liu, X X Jiang, Y H Zhu, D N We. Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine produces antidepressant effects in rats: role of brain-derived neurotrophic factor. Neuroscience vol 223 issue 2013 22890078 this sub-chronic treatment also increased hippocampal brain-derived neurotrophic factor (bdnf) protein levels in both non-stressed and stressed animals and restored the stress-induced down-regulation of bdnf expression. 2013-05-01 2022-01-12 Not clear
Jie Luo, Su Min, Ke Wei, Junfang Zhang, Yuanyuan Li. Propofol interacts with stimulus intensities of electroconvulsive shock to regulate behavior and hippocampal BDNF in a rat model of depression. Psychiatry research vol 198 issue 2 2013 22410590 to test our hypothesis that anesthetics interact with the intrinsic parameters of ect to differentially regulate its therapeutic efficacy, we investigated the effects of the anesthetic propofol and the stimulus intensities of ect on behavior and hippocampal brain-derived neurotrophic factor (bdnf) in a rodent model of depression. 2013-04-23 2022-01-12 Not clear
S Jha, B Dong, K Sakat. Enriched environment treatment reverses depression-like behavior and restores reduced hippocampal neurogenesis and protein levels of brain-derived neurotrophic factor in mice lacking its expression through promoter IV. Translational psychiatry vol 1 issue 2013 22832656 enriched environment treatment reverses depression-like behavior and restores reduced hippocampal neurogenesis and protein levels of brain-derived neurotrophic factor in mice lacking its expression through promoter iv. 2013-04-04 2022-01-12 Not clear
Irena Baranowska-Bosiacka, Izabela Gutowska, Marta Rybicka, Przemys\\xc5\\x82aw Nowacki, Dariusz Chlube. Neurotoxicity of lead. Hypothetical molecular mechanisms of synaptic function disorders. Neurologia i neurochirurgia polska vol 46 issue 6 2013 23319225 this review presents the hypothetical molecular mechanism by which pb disrupts synapse formation and plasticity in developing hippocampal neurons and the role of the nmda receptor-dependent signaling pathway and brain-derived neurotrophic factor (bdnf) as a mechanism of pb neurotoxicity at the synapse level. 2013-04-04 2022-01-12 Not clear
Tao Su, Raffaella Scardigli, Luisa Fasulo, Beatrice Paradiso, Mario Barbieri, Anna Binaschi, Roberta Bovolenta, Silvia Zucchini, Giulio Cossu, Antonino Cattaneo, Michele Simonat. Bystander effect on brain tissue of mesoangioblasts producing neurotrophins. Cell transplantation vol 21 issue 8 2013 22525962 we generated genetically modified mabs producing nerve growth factor (mabs-ngf) or brain-derived neurotrophic factor (mabs-bdnf) and assessed their bystander effects in vitro using pc12 cells, primary cultures, and organotypic cultures of adult hippocampal slices. 2013-04-01 2022-01-12 Not clear
C\\xc3\\xa1ssia Sallaberry, Fernanda Nunes, Marcelo S Costa, Gabriela T Fioreze, Ana Paula Ardais, Paulo Henrique S Botton, Bruno Klaudat, Thom\\xc3\\xa1s Forte, Diogo O Souza, Elaine Elisabetsky, Lisiane O Porci\\xc3\\xbancul. Chronic caffeine prevents changes in inhibitory avoidance memory and hippocampal BDNF immunocontent in middle-aged rats. Neuropharmacology vol 64 issue 2013 22841916 because brain-derived neurotrophic factor (bdnf) is associated with memory formation and bdnf's actions are modulated by adenosine receptors, the molecular targets for the psychostimulant actions of caffeine, we here compare the effects of chronic caffeine (1 mg/ml drinking solution for 30 days) on short- and long term memory and on levels of hippocampal probdnf, mature bdnf, trkb and creb in young (3 month old) and middle-aged (12 month old) rats. 2013-02-11 2022-01-12 Not clear
S-Y Yau, B W-M Lau, E-D Zhang, J C-D Lee, A Li, T M C Lee, Y-P Ching, A-M Xu, K-F S. Effects of voluntary running on plasma levels of neurotrophins, hippocampal cell proliferation and learning and memory in stressed rats. Neuroscience vol 222 issue 2013 22813995 previous studies have shown that a 2-week treatment with 40 mg/kg corticosterone (cort) in rats suppresses hippocampal neurogenesis and decreases hippocampal brain-derived neurotrophic factor (bdnf) levels and impairs spatial learning, all of which could be counteracted by voluntary wheel running. 2013-01-24 2022-01-12 Not clear
Bombi Lee, Bongjun Sur, Mijung Yeom, Insop Shim, Hyejung Lee, Dae-Hyun Hah. Effect of berberine on depression- and anxiety-like behaviors and activation of the noradrenergic system induced by development of morphine dependence in rats. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology vol 16 issue 6 2012 23269899 ber administration also significantly blocked the increase in hypothalamic crf expression and th expression in the locus coeruleus (lc) and the decrease in hippocampal brain-derived neurotrophic factor (bdnf) mrna expression. 2012-12-28 2022-01-12 Not clear
Satoshi Okuyama, Naoko Shimada, Miki Kaji, Mayu Morita, Kazuhiro Miyoshi, Sona Minami, Yoshiaki Amakura, Morio Yoshimura, Takashi Yoshida, Sono Watanabe, Mitsunari Nakajima, Yoshiko Furukaw. Heptamethoxyflavone, a citrus flavonoid, enhances brain-derived neurotrophic factor production and neurogenesis in the hippocampus following cerebral global ischemia in mice. Neuroscience letters vol 528 issue 2 2012 22985518 in the present study using a transient global ischemia mouse model, we showed that (1) a citrus flavonoid 3,5,6,7,8,3',4'-heptamethoxyflavone (hmf) induced the phosphorylation of extracellular signal-regulated kinases 1/2 (erk1/2) and camp response element-binding protein (creb) in the hippocampus after ischemia; (2) hmf increased the expression of brain-derived neurotrophic factor (bdnf), a representative neurotrophic factor in the central nervous system, in the hippocampal dentate gyrus, and most bdnf-positive cells were also stained with anti-glial fibrillary acidic protein (one of the major intermediate filament proteins of mature astrocytes) and (3) hmf increased doublecortin positive neuronal precursor cells in the dentate gyrus subventricular zone or subgranular zone. 2012-12-20 2022-01-12 Not clear
Bo Jiang, Zhe Xiong, Jun Yang, Wei Wang, Yue Wang, Zhuang-Li Hu, Fang Wang, Jian-Guo Che. Antidepressant-like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus. British journal of pharmacology vol 166 issue 6 2012 22335772 changes in hippocampal neurogenesis and spine density, the brain-derived neurotrophic factor (bdnf) signalling pathway, and serum corticosterone level after chronic stress and rg1 treatment were then investigated. 2012-11-05 2022-01-12 Not clear
Janet Alder, Brian C Kramer, Casey Hoskin, Smita Thakker-Vari. Brain-derived neurotrophic factor produced by human umbilical tissue-derived cells is required for its effect on hippocampal dendritic differentiation. Developmental neurobiology vol 72 issue 6 2012 21954108 brain-derived neurotrophic factor produced by human umbilical tissue-derived cells is required for its effect on hippocampal dendritic differentiation. 2012-09-28 2022-01-12 Not clear
Janet Alder, Brian C Kramer, Casey Hoskin, Smita Thakker-Vari. Brain-derived neurotrophic factor produced by human umbilical tissue-derived cells is required for its effect on hippocampal dendritic differentiation. Developmental neurobiology vol 72 issue 6 2012 21954108 the effect of hutc and hmsc on hippocampal cells in co-culture was comparable to those induced by treatment with recombinant human brain-derived neurotrophic factor (bdnf) implying that a similar factor may be released from hutc or hmsc. 2012-09-28 2022-01-12 Not clear
Alexander M Kleschevnikov, Pavel V Belichenko, Mehrdad Faizi, Lucia F Jacobs, Khin Htun, Mehrdad Shamloo, William C Moble. Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 32 issue 27 2012 22764230 the treatment increased hippocampal levels of brain-derived neurotrophic factor, equally in 2n and ts65dn mice. 2012-09-18 2022-01-12 Not clear
Sylvie Burnouf, Karim Belarbi, Laetitia Troquier, Maxime Derisbourg, Dominique Demeyer, Antoine Leboucher, Cyril Laurent, Malika Hamdane, Luc Buee, David Blu. Hippocampal BDNF expression in a tau transgenic mouse model. Current Alzheimer research vol 9 issue 4 2012 22272617 brain-derived neurotrophic factor (bdnf) is a neurotrophic factor playing a critical role in hippocampal synaptic plasticity and memory and whose levels have been shown reduced in ad brains. 2012-09-07 2022-01-12 Not clear
Melissa J Glenn, Raven S Adams, Lauren McClur. Supplemental dietary choline during development exerts antidepressant-like effects in adult female rats. Brain research vol 1443 issue 2012 22305146 we previously found that choline supplementation increased adult hippocampal neurogenesis, a function compromised by stress, lowered in depression, and boosted by antidepressants; and increased levels of growth factors linked to depression, like brain-derived neurotrophic factor. 2012-09-04 2022-01-12 Not clear
Nancy A Dennis, Roberto Cabeza, Anna C Need, Sheena Waters-Metenier, David B Goldstein, Kevin S LaBa. Brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks. Hippocampus vol 21 issue 9 2012 20865733 brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks. 2012-08-24 2022-01-12 Not clear
Nancy A Dennis, Roberto Cabeza, Anna C Need, Sheena Waters-Metenier, David B Goldstein, Kevin S LaBa. Brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks. Hippocampus vol 21 issue 9 2012 20865733 brain-derived neurotrophic factor (bdnf) is a neurotrophin which has been shown to regulate cell survival and proliferation, as well as synaptic growth and hippocampal long-term potentiation. 2012-08-24 2022-01-12 Not clear
Orestes V Forlenza, Vanessa J de Paula, Rodrigo Machado-Vieira, Breno S Diniz, Wagner F Gatta. Does lithium prevent Alzheimer's disease? Drugs & aging vol 29 issue 5 2012 22500970 in humans, lithium treatment has been associated with humoral and structural evidence of neuroprotection, such as increased expression of anti-apoptotic genes, inhibition of cellular oxidative stress, synthesis of brain-derived neurotrophic factor (bdnf), cortical thickening, increased grey matter density, and hippocampal enlargement. 2012-08-15 2022-01-12 Not clear
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