| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sang-Seo Park, Seong-Hyun Kim, Chang-Ju Kim, Mal-Soon Shin, Yun-Jin Park, Tae-Woon Ki. Effects of exercise and microbiota transplant on the memory of obesity-induced mice. Journal of exercise rehabilitation. vol 18. issue 3. 2022-07-18. PMID:35846232. |
the short-term memory and spatial learning memory were determined by step-down avoidance test and morris water maze task, immunohistochemistry for glial fibrillary acidic protein, western blot analysis for brain-derived neurotrophic factor and tropomyosin receptor kinase b were performed in the hippocampus. |
2022-07-18 |
2023-08-14 |
mouse |
| Tingliang Gong, Zhaoliang Luo, Li Huang, Caixian Xiao, Junlu Yi, Junfeng Yan, Qian Chen, Weihong Li, Wenqiang Ta. Effect and Mechanism of Yisui Fuyongtang (YSFYT) Decoction on Cognitive Function and Synaptic Plasticity in Rats with Vascular Cognitive Impairment. Journal of immunology research. vol 2022. 2022-07-18. PMID:35846430. |
further pathology and protein detection methods were adopted to investigate the action of ysfyt decoction on the neurons in the hippocampus of model rats and the regulation of the brain derived neurotrophic factor (bdnf)-tyrosine protein kinase receptor b (trkb) signaling pathway. |
2022-07-18 |
2023-08-14 |
rat |
| Nouf M Alyami, Saba Abdi, Hanadi M Alyami, Rafa Almee. Proanthocyanidins alleviate pentylenetetrazole-induced epileptic seizures in mice via the antioxidant activity. Neurochemical research. 2022-07-15. PMID:35838827. |
moreover, ache activity, da, ne, 5-ht, brain-derived neurotrophic factor levels, and gene expression of nrf2 have decreased in the hippocampal tissue of ptz exposed mice. |
2022-07-15 |
2023-08-14 |
mouse |
| Riley A Williams, Kenneth W Johnson, Francis S Lee, Hugh C Hemmings, Jimcy Plathol. A Common Human Brain-Derived Neurotrophic Factor Polymorphism Leads to Prolonged Depression of Excitatory Synaptic Transmission by Isoflurane in Hippocampal Cultures. Frontiers in molecular neuroscience. vol 15. 2022-07-11. PMID:35813074. |
a common human brain-derived neurotrophic factor polymorphism leads to prolonged depression of excitatory synaptic transmission by isoflurane in hippocampal cultures. |
2022-07-11 |
2023-08-14 |
mouse |
| Gyuho Lee, Yunwook Kim, Jung-Hee Jang, Chan Lee, Jaewoo Yoon, Nayoung Ahn, Kijin Ki. Effects of an Exercise Program Combining Aerobic and Resistance Training on Protein Expressions of Neurotrophic Factors in Obese Rats Injected with Beta-Amyloid. International journal of environmental research and public health. vol 19. issue 13. 2022-07-09. PMID:35805580. |
changes in physical fitness, cognitive function, blood levels of beta-amyloid and metabolic factors, and protein expressions of neurotrophic factors related to brain function such as bdnf (brain-derived neurotrophic factor) in the quadriceps femoris, hippocampus, and cerebral cortex were analyzed. |
2022-07-09 |
2023-08-14 |
human |
| Joanna Winstone, Hana Shafique, Madeleine E Clemmer, Ken Mackie, Jim Wager-Mille. Effects of Tetrahydrocannabinol and Cannabidiol on Brain-Derived Neurotrophic Factor and Tropomyosin Receptor Kinase B Expression in the Adolescent Hippocampus. Cannabis and cannabinoid research. 2022-05-31. PMID:35639364. |
effects of tetrahydrocannabinol and cannabidiol on brain-derived neurotrophic factor and tropomyosin receptor kinase b expression in the adolescent hippocampus. |
2022-05-31 |
2023-08-13 |
Not clear |
| Rintaro Fujii, Keita Watanabe, Naomichi Okamoto, Tomoya Natsuyama, Hirofumi Tesen, Ryohei Igata, Yuki Konishi, Atsuko Ikenouchi, Shingo Kakeda, Reiji Yoshimur. Hippocampal Volume and Plasma Brain-Derived Neurotrophic Factor Levels in Patients With Depression and Healthy Controls. Frontiers in molecular neuroscience. vol 15. 2022-05-23. PMID:35600081. |
hippocampal volume and plasma brain-derived neurotrophic factor levels in patients with depression and healthy controls. |
2022-05-23 |
2023-08-13 |
Not clear |
| Xiao-Bing Li, Rong-Rong Yuan, Qixia Wang, Shouyu Chai, Zhengying Zhang, Yue Wang, Shu-Hong Huan. Brain-Derived Neurotrophic Factor regulates LYN kinase mediated Myosin Light Chain Kinase activation to modulate non-muscle myosin II activity in hippocampal neurons. The Journal of biological chemistry. 2022-05-22. PMID:35598826. |
brain-derived neurotrophic factor regulates lyn kinase mediated myosin light chain kinase activation to modulate non-muscle myosin ii activity in hippocampal neurons. |
2022-05-22 |
2023-08-13 |
mouse |
| Hanxue Wu, Jinzhu Zhuang, Jiawei Wang, Shenglan Yuan, Hui Sun, Jiaxi X. AT FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556110. |
in both prefrontal cortex and hippocampus, the mrna levels of bdnf (brain-derived neurotrophic factor) and pi4kiiiβ (phosphatidylinositol 4-kinase iiiβ) were found to be significantly lower in hypertensive nt mice. |
2022-05-13 |
2023-08-13 |
mouse |
| Chong Gao, Meiling Wu, Qiaohui Du, Jiagang Deng, Jiangang She. Naringin Mediates Adult Hippocampal Neurogenesis for Antidepression via Activating CREB Signaling. Frontiers in cell and developmental biology. vol 10. 2022-04-28. PMID:35478969. |
meanwhile, naringin treatment increased phosphorylation of camp response element binding protein (creb) but had no effect on the expression of brain-derived neurotrophic factor and phosphorylation of trkb in the hippocampus of cort-induced depressive mice. |
2022-04-28 |
2023-08-13 |
mouse |
| Kanishk Luhach, Giriraj T Kulkarni, Vijay P Singh, Bhupesh Sharm. Vinpocetine ameliorates developmental hyperserotonemia induced behavioral and biochemical changes: role of neuronal function, inflammation, and oxidative stress. Acta neurobiologiae experimentalis. vol 82. issue 1. 2022-04-22. PMID:35451422. |
also, effects on biochemical markers related with neuronal function brain derived neurotrophic factor (bdnf) and phosphorylated camp response element binding protein (pcreb), inflammation interleukins (il‑6 and il‑10) and tumor necrosis factor-alpha (tnf‑α), and oxidative stress (tbars and gsh) were studied in important brain areas (frontal cortex, cerebellum, hippocampus, and striatum). |
2022-04-22 |
2023-08-13 |
rat |
| Jin Li, Xiaobin Zhang, Jiangling Jiang, Bin Zhang, Yingying Tang, Tianhong Zhang, Yuping Jia, Qingwei Li, Mengqing Xia, Jianhua Sheng, Chunbo Li, Jijun Wan. Comparison of electroconvulsive therapy and magnetic seizure therapy in schizophrenia: Structural changes/neuroplasticity. Psychiatry research. vol 312. 2022-04-04. PMID:35378453. |
in addition, we examined the possible contributions of hippocampal volume changes and enhanced brain derived neurotrophic factor (bdnf) signaling to the therapeutic responses. |
2022-04-04 |
2023-08-13 |
Not clear |
| Amy E Margolis, Ran Liu, Vasco A Conceição, Bruce Ramphal, David Pagliaccio, Mariah L DeSerisy, Emily Koe, Ena Selmanovic, Amarelis Raudales, Nur Emanet, Aurabelle E Quinn, Beatrice Beebe, Brandon L Pearson, Julie B Herbstman, Virginia A Rauh, William P Fifer, Nathan A Fox, Frances A Champagn. Convergent neural correlates of prenatal exposure to air pollution and behavioral phenotypes of risk for internalizing and externalizing problems: Potential biological and cognitive pathways. Neuroscience and biobehavioral reviews. 2022-04-03. PMID:35367513. |
we conclude that prenatal exposure to air pollutants increases risk for behavioral inhibition and irritability through distinct mechanisms, including altered dopaminergic signaling and hippocampal morphology, neuroinflammation, and decreased brain-derived neurotrophic factor expression. |
2022-04-03 |
2023-08-13 |
human |
| Shengying Pan, Yaoying Ma, Rongrong Yang, Xu Lu, Qingsheng You, Ting Ye, Chao Huan. Indole-3-Carbinol Selectively Prevents Chronic Stress-Induced Depression-but not Anxiety-Like Behaviors via Suppressing Pro-Inflammatory Cytokine Production and Oxido-Nitrosative Stress in the Brain. Frontiers in pharmacology. vol 13. 2022-03-04. PMID:35242039. |
further analysis showed that repeated i3c treatment (60 mg/kg, 10 days) prevented csds-induced increases in levels of nitrite and malondialdehyde (mda), decreases in contents of glutathione (gsh), and decreases in levels of brain derived neurotrophic factor (bdnf) protein in the hippocampus and prefrontal cortex. |
2022-03-04 |
2023-08-13 |
mouse |
| Paloma T Birmann, Angela M Casaril, Giuliana P Zugno, Gabriela G Acosta, Fernanda Severo Sabedra Sousa, Tiago Collares, Fabiana K Seixas, Raquel G Jacob, César A Brüning, Lucielli Savegnago, Daniela Hartwi. Flower essential oil of Tagetes minuta mitigates oxidative stress and restores BDNF-Akt/ERK2 signaling attenuating inflammation- and stress-induced depressive-like behavior in mice. Brain research. 2022-02-27. PMID:35219720. |
this effect is most likely due to the reversal of oxidative stress in the hippocampus of mice, the decrease in plasma corticosterone levels, and restoration of the mrna levels of brain-derived neurotrophic factor, phosphatidylinositol-3-kinase, protein kinase b, and extracellular signal-regulated kinase 2. |
2022-02-27 |
2023-08-13 |
mouse |
| Bingqian Zhou, Ge Jin, Xiaoqi Pang, Qi Mo, Jie Bao, Tiaotiao Liu, Jingyi Wu, Runxiang Xie, Xiang Liu, Jinghua Liu, Hongwei Yang, Xin Xu, Bangmao Wang, Hailong Ca. Lactobacillus rhamnosus GG colonization in early life regulates gut-brain axis and relieves anxiety-like behavior in adulthood. Pharmacological research. 2022-01-22. PMID:35065201. |
mechanically, lgg colonization activated epithelial growth factor receptor (egfr) and enhanced serotonin transporter (sert) expression and modulated serotonergic system in the intestine, and increased brain-derived neurotrophic factor and γ-aminobutyric acid receptor levels in the hippocampus and amygdala. |
2022-01-22 |
2023-08-13 |
mouse |
| Joachim Hr Lübke, Faezeh Idoon, Mina Mohasel-Roodi, Fatemeh Alipour, Javad Hami, Alireza Ehteshampour, Hamideh Mostafaee, Akram Sadegh. Neurotrophic factors in Alzheimer's disease: pathogenesis and therapy. Acta neurobiologiae experimentalis. vol 81. issue 4. 2022-01-11. PMID:35014981. |
in ad brains, an increase in nerve growth factor and a decrease in brain-derived neurotrophic factor in the hippocampus and certain neocortical regions, and a decrease in trka in the cortex and nucleus basalis has been observed. |
2022-01-11 |
2023-08-13 |
human |
| Natalija Arsenijevic, Dragica Selakovic, Jelena S Katanic Stankovic, Vladimir Mihailovic, Slobodanka Mitrovic, Jovana Milenkovic, Pavle Milanovic, Miroslav Vasovic, Aleksandra Nikezic, Olivera Milosevic-Djordjevic, Marko Zivanovic, Nenad Filipovic, Vladimir Jakovljevic, Nemanja Jovicic, Gvozden Rosi. Variable neuroprotective role of Filipendula ulmaria extract in rat hippocampus. Journal of integrative neuroscience. vol 20. issue 4. 2022-01-08. PMID:34997711. |
moreover, the hippocampal immunoreactivity for brain-derived neurotrophic factor and gabaergic-a receptors was significantly lower following calcium phosphate nanoparticles intake. |
2022-01-08 |
2023-08-13 |
rat |
| Natalija Arsenijevic, Dragica Selakovic, Jelena S Katanic Stankovic, Vladimir Mihailovic, Slobodanka Mitrovic, Jovana Milenkovic, Pavle Milanovic, Miroslav Vasovic, Aleksandra Nikezic, Olivera Milosevic-Djordjevic, Marko Zivanovic, Nenad Filipovic, Vladimir Jakovljevic, Nemanja Jovicic, Gvozden Rosi. Variable neuroprotective role of Filipendula ulmaria extract in rat hippocampus. Journal of integrative neuroscience. vol 20. issue 4. 2022-01-08. PMID:34997711. |
the increased hippocampal immunoreactivity for brain-derived neurotrophic factor, gabaergic-a receptors and significant anxiolytic-like effects of filipendula ulmaria may suggest a beneficial role of antioxidant supplementation in preventing anxiogenic response to nano-sized calcium phosphates. |
2022-01-08 |
2023-08-13 |
rat |
| Yuan Zhou, Shao-Fu Li, Li-Sha Deng, Yong-Kang Ma, Gang Lei, Yong-Hui Dan. HINT1 deficiency in aged mice reduces anxiety-like and depression-like behaviours and enhances cognitive performances. Experimental gerontology. 2022-01-07. PMID:34995725. |
in a battery of behavioural tests, aged wild-type mice showed increased anxiety-like and depression-like behaviours and decreased cognitive performance, along with lower expression levels of glutathione peroxidase, enhanced amount of malondialdehyde, and decreased expression levels of brain-derived neurotrophic factor and tyrosine kinase b in the hippocampus and pfc compared to young wild-type mice. |
2022-01-07 |
2023-08-13 |
mouse |