Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Y L Ma, H L Wang, H C Wu, C L Wei, E H Le. Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats. Neuroscience. vol 82. issue 4. 1998-03-26. PMID:9466420. |
we have examined the relationship between brain-derived neurotrophic factor gene expression in the hippocampus and memory retention as well as long-term potentiation of rats. |
1998-03-26 |
2023-08-12 |
rat |
Y L Ma, H L Wang, H C Wu, C L Wei, E H Le. Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats. Neuroscience. vol 82. issue 4. 1998-03-26. PMID:9466420. |
results revealed that brain-derived neurotrophic factor messenger rna levels in the dentate gyrus of the hippocampus were markedly increased at 1 h, 3 h and 6 h post-training in rats showing good retention performance when compared with the poor retention controls. |
1998-03-26 |
2023-08-12 |
rat |
Y L Ma, H L Wang, H C Wu, C L Wei, E H Le. Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats. Neuroscience. vol 82. issue 4. 1998-03-26. PMID:9466420. |
direct injection of brain-derived neurotrophic factor antisense oligonucleotide into the dentate gyrus of the hippocampus before memory consolidation takes place markedly impaired retention performance in rats. |
1998-03-26 |
2023-08-12 |
rat |
Y L Ma, H L Wang, H C Wu, C L Wei, E H Le. Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats. Neuroscience. vol 82. issue 4. 1998-03-26. PMID:9466420. |
these results suggest that hippocampal brain-derived neurotrophic factor gene expression plays an important role in the memory consolidation process and in the expression of long-term potentiation in rats. |
1998-03-26 |
2023-08-12 |
rat |
Y Nakagami, H Saito, N Matsuk. Basic fibroblast growth factor and brain-derived neurotrophic factor promote survival and neuronal circuit formation in organotypic hippocampal culture. Japanese journal of pharmacology. vol 75. issue 4. 1998-03-24. PMID:9469637. |
basic fibroblast growth factor and brain-derived neurotrophic factor promote survival and neuronal circuit formation in organotypic hippocampal culture. |
1998-03-24 |
2023-08-12 |
Not clear |
E Elmér, Z Kokaia, M Kokaia, J Carnahan, H Nawa, O Lindval. Dynamic changes of brain-derived neurotrophic factor protein levels in the rat forebrain after single and recurring kindling-induced seizures. Neuroscience. vol 83. issue 2. 1998-03-12. PMID:9460745. |
regional levels of brain-derived neurotrophic factor protein were measured in the rat brain using enzyme immunoassay following seizures evoked by hippocampal kindling stimulations. |
1998-03-12 |
2023-08-12 |
rat |
E Elmér, Z Kokaia, M Kokaia, J Carnahan, H Nawa, O Lindval. Dynamic changes of brain-derived neurotrophic factor protein levels in the rat forebrain after single and recurring kindling-induced seizures. Neuroscience. vol 83. issue 2. 1998-03-12. PMID:9460745. |
one stimulation, which induced a brief, single episode of epileptiform activity in hippocampus and piriform cortex but not in parietal cortex or striatum, gave rise to a transient increase of brain-derived neurotrophic factor levels in dentate gyrus and ca3 region and a decrease in piriform cortex. |
1998-03-12 |
2023-08-12 |
rat |
P R Blanquet, Y Lamou. Brain-derived neurotrophic factor increases Ca2+/calmodulin-dependent protein kinase 2 activity in hippocampus. The Journal of biological chemistry. vol 272. issue 39. 1997-10-23. PMID:9305859. |
brain-derived neurotrophic factor increases ca2+/calmodulin-dependent protein kinase 2 activity in hippocampus. |
1997-10-23 |
2023-08-12 |
rat |
I Ferencz, M Kokaia, M Keep, E Elmér, M Metsis, Z Kokaia, O Lindval. Effects of cholinergic denervation on seizure development and neurotrophin messenger RNA regulation in rapid hippocampal kindling. Neuroscience. vol 80. issue 2. 1997-10-17. PMID:9284342. |
no differences in the seizure-evoked levels of neurotrophin and trk messenger rnas were detected, except in the dentate granule cell layer, which had significantly higher brain-derived neurotrophic factor messenger rna expression in the lesioned animals at 2 h. in conclusion, the basal forebrain cholinergic system (i) dampens the severity of recurring seizures induced by rapid hippocampal kindling stimulations, but has no effect on the subsequent delayed phase of epileptogenesis; and (ii) exerts a tonic stimulation of basal brain-derived neurotrophic factor messenger rna levels in the hippocampal formation and piriform cortex. |
1997-10-17 |
2023-08-12 |
rat |
Y K Kwo. Expression of brain-derived neurotrophic factor mRNA stimulated by basic fibroblast growth factor and platelet-derived growth factor in rat hippocampal cell line. Molecules and cells. vol 7. issue 3. 1997-10-06. PMID:9264017. |
expression of brain-derived neurotrophic factor mrna stimulated by basic fibroblast growth factor and platelet-derived growth factor in rat hippocampal cell line. |
1997-10-06 |
2023-08-12 |
rat |
M A Smith, L X Zhang, W E Lyons, L A Mamouna. Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223060. |
anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers. |
1997-08-29 |
2023-08-12 |
Not clear |
R S Duman, G R Heninger, E J Nestle. A molecular and cellular theory of depression. Archives of general psychiatry. vol 54. issue 7. 1997-08-05. PMID:9236543. |
the activated cyclic adenosine 3',5'-monophosphate system leads to the regulation of specific target genes, including the increased expression of brain-derived neurotrophic factor in certain populations of neurons in the hippocampus and cerebral cortex. |
1997-08-05 |
2023-08-12 |
Not clear |
R S Duman, G R Heninger, E J Nestle. A molecular and cellular theory of depression. Archives of general psychiatry. vol 54. issue 7. 1997-08-05. PMID:9236543. |
the importance of these changes is highlighted by the discovery that stress can decrease the expression of brain-derived neurotrophic factor and lead to atrophy of these same populations of stress-vulnerable hippocampal neurons. |
1997-08-05 |
2023-08-12 |
Not clear |
Q Yan, R D Rosenfeld, C R Matheson, N Hawkins, O T Lopez, L Bennett, A A Welche. Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system. Neuroscience. vol 78. issue 2. 1997-08-01. PMID:9145800. |
however, kainate treatments greatly increased brain-derived neurotrophic factor immunoreactivity in the pyramidal cells of the ca1 region, as well as in the dentate gyrus, ca2 and ca3 hippocampal regions. |
1997-08-01 |
2023-08-12 |
rat |
M Marcinkiewicz, T Nagao, R Day, N G Seidah, M Chrétien, M Avol. Pilocarpine-induced seizures are accompanied by a transient elevation in the messenger RNA expression of the prohormone convertase PC1 in rat hippocampus: comparison with nerve growth factor and brain-derived neurotrophic factor expression. Neuroscience. vol 76. issue 2. 1997-04-29. PMID:9015327. |
pilocarpine-induced seizures are accompanied by a transient elevation in the messenger rna expression of the prohormone convertase pc1 in rat hippocampus: comparison with nerve growth factor and brain-derived neurotrophic factor expression. |
1997-04-29 |
2023-08-12 |
rat |
M Marcinkiewicz, T Nagao, R Day, N G Seidah, M Chrétien, M Avol. Pilocarpine-induced seizures are accompanied by a transient elevation in the messenger RNA expression of the prohormone convertase PC1 in rat hippocampus: comparison with nerve growth factor and brain-derived neurotrophic factor expression. Neuroscience. vol 76. issue 2. 1997-04-29. PMID:9015327. |
moreover, we compared their expression patterns with those of neurotrophins such as nerve growth factor and brain-derived neurotrophic factor, which are up-regulated in the hippocampus during seizures. |
1997-04-29 |
2023-08-12 |
rat |
M Marcinkiewicz, T Nagao, R Day, N G Seidah, M Chrétien, M Avol. Pilocarpine-induced seizures are accompanied by a transient elevation in the messenger RNA expression of the prohormone convertase PC1 in rat hippocampus: comparison with nerve growth factor and brain-derived neurotrophic factor expression. Neuroscience. vol 76. issue 2. 1997-04-29. PMID:9015327. |
induced seizure activity that appeared within the first hour and persisted for approximately 8 h. in situ hybridization showed transient increases in messenger rna for nerve growth factor and brain-derived neurotrophic factor that peaked at 120 min in the hippocampus. |
1997-04-29 |
2023-08-12 |
rat |
M Marcinkiewicz, T Nagao, R Day, N G Seidah, M Chrétien, M Avol. Pilocarpine-induced seizures are accompanied by a transient elevation in the messenger RNA expression of the prohormone convertase PC1 in rat hippocampus: comparison with nerve growth factor and brain-derived neurotrophic factor expression. Neuroscience. vol 76. issue 2. 1997-04-29. PMID:9015327. |
thus, in the rat hippocampus, the epileptiform activity induced by pilocarpine mediates a co-ordinated expression of messenger rnas for pc1, nerve growth factor and brain-derived neurotrophic factor. |
1997-04-29 |
2023-08-12 |
rat |
V A Vaidya, G J Marek, G K Aghajanian, R S Duma. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 8. 1997-04-28. PMID:9092600. |
5-ht2a receptor-mediated regulation of brain-derived neurotrophic factor mrna in the hippocampus and the neocortex. |
1997-04-28 |
2023-08-12 |
Not clear |
M Korte, V Staiger, O Griesbeck, H Thoenen, T Bonhoeffe. The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments. Journal of physiology, Paris. vol 90. issue 3-4. 1997-04-24. PMID:9116659. |
the involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments. |
1997-04-24 |
2023-08-12 |
mouse |