| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qi-Chen Yuan, Han Gong, Min Du, Xue-Ying Ma. Supplementation of milk polar lipids to obese dams improves neurodevelopment and cognitive function in male offspring. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 35. issue 4. 2021-07-21. PMID:33749945. |
insulin resistance and aberrant brain-derived neurotrophic factor signaling were induced in the hippocampus of neonatal and adult offspring due to maternal and progeny hfd, but recovered by maternal mfgm-pl administration. |
2021-07-21 |
2023-08-13 |
rat |
| Mohadeseh Chahkandi, Gholamreza Komeili, Gholamreza Sepehri, Mohammad Khaksari, Sedigheh Amiresmail. Marijuana and β-estradiol interactions on spatial learning and memory in young female rats: Lack of role of the G protein-coupled estrogen receptor (GPR30). Life sciences. vol 280. 2021-07-20. PMID:34146552. |
we also assessed the bdnf (brain-derived neurotrophic factor) concentration and the hippocampal level of gpr30. |
2021-07-20 |
2023-08-13 |
rat |
| Basem H Elesawy, Walaa F Alsanie, Mubarak Ali Algahtany, Jawaher M Al-Ashkhari, Aya K Alyarobi, Hussein F Sak. Whole and refined grains change behavior and reduce brain derived neurotrophic factor and neurotrophin-3 in rats. Journal of food biochemistry. 2021-07-19. PMID:34278588. |
after 12 weeks, we measured the hippocampal and prefrontal cortical brain derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), 5-hydroxytryptamine, dopamine, norepinephrine, malondialdehyde (mda) and reduced glutathione (gsh) levels. |
2021-07-19 |
2023-08-13 |
rat |
| Sofie D Shirenova, Nadezhda N Khlebnikova, Nataliya A Krupin. Long-Term Social Isolation Reduces Expression of the BDNF Precursor and Prolyl Endopeptidase in the Rat Brain. Biochemistry. Biokhimiia. vol 86. issue 6. 2021-07-15. PMID:34225593. |
the present study aimed to assess synaptophysin (syp), brain-derived neurotrophic factor precursor (probdnf), and prep expression using western blot in the brain structures - the hippocampus, frontal cortex, and striatum of the rats subjected to prolonged social isolation compared with group-housed animals. |
2021-07-15 |
2023-08-13 |
rat |
| Ali Rashidy-Pour, Leila Derafshpour, Abbas Ali Vafaei, Ahmad Reza Bandegi, Adel Kashefi, Hamid Reza Sameni, Nahid Jashire-Nezhad, Ehsan Saboory, Yosef Panah. Effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. Behavioural pharmacology. vol 31. issue 7. 2021-07-08. PMID:32826427. |
effects of treadmill exercise and sex hormones on learning, memory and hippocampal brain-derived neurotrophic factor levels in transient congenital hypothyroid rats. |
2021-07-08 |
2023-08-13 |
rat |
| Babatunde Oluwafemi Adetuyi, Ebenezer Olatunde Faromb. 6-Gingerol, an active constituent of ginger, attenuates lipopolysaccharide-induced oxidation, inflammation, cognitive deficits, neuroplasticity, and amyloidogenesis in rat. Journal of food biochemistry. vol 45. issue 4. 2021-07-08. PMID:33624846. |
furthermore, induction of amyloidogenesis associated with disruption of histoarchitecture and high expression of interleukin 1β, inducible nitric oxide synthase, amyloid precursor protein (app), β-secretase 1, and brain-derived neurotrophic factor by lps was mitigated by the two doses of 6g in the rat hippocampus and cerebral cortex region of the brain. |
2021-07-08 |
2023-08-13 |
rat |
| Qiongqiong Zhan, Yanfeng Wu, Lin Li. Effects of notoginsenoside R1 on attenuating depressive behavior induced by chronic stress in rats through induction of PI3K/AKT/NF-κB pathway. Drug development research. 2021-06-26. PMID:34173680. |
subsequently, the morphology of hippocampal neurons and protein expression of brain-derived neurotrophic factor in each group were examined by hematoxylin and eosin staining and western blot to show the neuroprotective effects of ngr1. |
2021-06-26 |
2023-08-13 |
rat |
| Zhen Wang, Xiao Lin Zhong, Yang Xu, Jie He, Zheng Hai Liu, Ai Tao Nai, Lei Niu, Shi Shi Luo, Hui Yang, Jia Yu Zeng, Shu Ya He, Xi Chen, Wei Wan, Wen Yu Ca. Irradiation increases brain-derived neurotrophic factor precursor signaling in the mouse hippocampus. Neurobiology of learning and memory. vol 171. 2021-06-25. PMID:32084558. |
irradiation increases brain-derived neurotrophic factor precursor signaling in the mouse hippocampus. |
2021-06-25 |
2023-08-13 |
mouse |
| Samaneh Shamsipour, Gholamreza Sharifi, Farzaneh Taghia. Impact of interval training with probiotic (L. plantarum / Bifidobacterium bifidum) on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimer's disease. Neuroscience letters. vol 756. 2021-06-22. PMID:33974953. |
to take this line of research further, this study was aimed at investigating the impact of moderate-intensity interval training (miit) with a combined administration of lactobacillus plantarum and bifidobacterium bifidum (probiotic, brob) on the passive avoidance test (shuttle box), choline acetyltransferase (chat) and the brain derived neurotrophic factor (bdnf) in the hippocampus of a rat model of ad. |
2021-06-22 |
2023-08-13 |
rat |
| Lubica Horvathova, Andrej Tillinger, Alexandra Padova, Jozef Bizik, Boris Mrave. Changes in gene expression in brain structures related to visceral sensation, autonomic functions, food intake, and cognition in melanoma-bearing mice. The European journal of neuroscience. vol 51. issue 12. 2021-06-21. PMID:31883212. |
in addition, we found reduced mrna levels of bcl-2, brain-derived neurotrophic factor, and doublecortin in the hippocampus. |
2021-06-21 |
2023-08-13 |
mouse |
| Fu Li, Haitao Xiang, Jiashu Lu, Zhuo Chen, Chao Huang, Xiaomei Yua. Lycopene ameliorates PTSD-like behaviors in mice and rebalances the neuroinflammatory response and oxidative stress in the brain. Physiology & behavior. vol 224. 2021-06-21. PMID:32592701. |
lycopene treatment (20 mg/kg, 12 days) also suppressed the sps-induced decrease in brain derived neurotrophic factor (bdnf) levels in the hippocampus and prefrontal cortex in mice. |
2021-06-21 |
2023-08-13 |
mouse |
| An-Rong Wang, Lian-Fang Mi, Zhi-Lei Zhang, Ming-Zhe Hu, Ze-Yu Zhao, Bin Liu, Yan-Bin Li, Shu Zhen. Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway. Behavioural brain research. vol 403. 2021-06-18. PMID:33493495. |
western blot and immunohistochemistry were adopted to evaluate expression of phosphorylated camp response element binding protein(p-creb), brain derived neurotrophic factor(bdnf) and apoptosis-related molecules in the dentate gyrus region of rat hippocampus. |
2021-06-18 |
2023-08-13 |
rat |
| Jizu Ling, Qin Yu, Yuning Li, Xinhui Yuan, Xiaoya Wang, Weiying Liu, Ting Guo, Yanni Duan, Lifang L. Edaravone Improves Intermittent Hypoxia-Induced Cognitive Impairment and Hippocampal Damage in Rats. Biological & pharmaceutical bulletin. vol 43. issue 8. 2021-05-28. PMID:32475934. |
furthermore, edaravone significantly increased the inhibition of hydroxyl free radicals; reduced expressions of superoxide anion, malondialdehyde, and 8-hydroxy-2'-deoxyguanosine; and upregulated the expression of manganese superoxide dismutase, catalase, camp, protein kinase a, phosphorylated-camp response element-binding (p-creb), b-cell lymphoma 2, and brain-derived neurotrophic factor in the hippocampal tissue of ih rats. |
2021-05-28 |
2023-08-13 |
rat |
| Cheryl A Frye, Vincent F Lembo, Alicia A Wal. Progesterone's Effects on Cognitive Performance of Male Mice Are Independent of Progestin Receptors but Relate to Increases in GABA Frontiers in endocrinology. vol 11. 2021-05-26. PMID:33505354. |
we hypothesized if progestogen's effects on cognitive performance are through its metabolite allopregnanolone, and not actions via binding to traditional progestin receptors (prs), then progesterone administration would enhance performance in tasks mediated by the hippocampus and cortex, coincident with increasing allopregnanolone concentrations, brain derived neurotrophic factor (bdnf) and/or muscimol binding of pr knock out (prko) and wild-type pr replete mice. |
2021-05-26 |
2023-08-13 |
mouse |
| Hsiao-Ling Chen, Ying-Wei Lan, Min-Yu Tu, Yu-Tang Tung, Megan Ning-Yu Chan, Hsin-Shan Wu, Chih-Ching Yen, Chuan-Mu Che. Kefir peptides exhibit antidepressant-like activity in mice through the BDNF/TrkB pathway. Journal of dairy science. vol 104. issue 6. 2021-05-24. PMID:33741171. |
overexpression of brain-derived neurotrophic factor, phosphorylated tropomyosin receptor kinase b, and phosphorylated erk1/2 protein levels could be detected in the hippocampus under kp administration. |
2021-05-24 |
2023-08-13 |
mouse |
| Li Zhou, Feng-Lin Pen. An extension of unpredictable chronic stress on brain-derived neurotrophic factor expression in different aged rats hippocampus. Chinese medical journal. vol 133. issue 16. 2021-05-14. PMID:32826476. |
an extension of unpredictable chronic stress on brain-derived neurotrophic factor expression in different aged rats hippocampus. |
2021-05-14 |
2023-08-13 |
rat |
| b' Javier Maximiliano Cordier, Julieta Paola Aguggia, V\\xc3\\xadctor Danelon, Franco Rafael Mir, Mar\\xc3\\xada Ang\\xc3\\xa9lica Rivarola, Daniel Masc\\xc3\\xb. Postweaning Enriched Environment Enhances Cognitive Function and Brain-Derived Neurotrophic Factor Signaling in the Hippocampus in Maternally Separated Rats. Neuroscience. vol 453. 2021-05-14. PMID:33039520.' |
postweaning enriched environment enhances cognitive function and brain-derived neurotrophic factor signaling in the hippocampus in maternally separated rats. |
2021-05-14 |
2023-08-13 |
rat |
| Mohammad Jodeiri Farshbaf, Karina Alviñ. Multiple Roles in Neuroprotection for the Exercise Derived Myokine Irisin. Frontiers in aging neuroscience. vol 13. 2021-05-04. PMID:33935687. |
irisin also crosses the blood brain barrier and initiates a neuroprotective genetic program in the hippocampus that culminates with increased expression of brain derived neurotrophic factor (bdnf). |
2021-05-04 |
2023-08-13 |
Not clear |
| Ying Guo, Jianping Xie, Lanchun Zhang, Lingli Yang, Jiaqing Ma, Yufan Bai, Wenjie Ma, Ling Wang, Haofei Yu, Yueqin Zeng, Haiyun Luo, Rongping Zhan. Ginsenoside Rb1 exerts antidepressant-like effects via suppression inflammation and activation of AKT pathway. Neuroscience letters. vol 744. 2021-04-30. PMID:33359924. |
furthermore, grb1 increased the protein expressions of brain-derived neurotrophic factor and phospho- protein kinase b/ protein kinase b (p-akt/akt), and decreased the protein expressions of interleukin-1β (il-1β), tumor necrosis factor α (tnf-α) and ionized calcium binding adapter molecule 1 in hippocampus, reduced the levels il-1β and tnf-α in serum. |
2021-04-30 |
2023-08-13 |
mouse |
| Zhe Xu, Bin Qia. Sevoflurane anesthesia-mediated oxidative stress and cognitive impairment in hippocampal neurons of old rats can be ameliorated by expression of brain derived neurotrophic factor. Neuroscience letters. vol 721. 2021-04-19. PMID:32027953. |
sevoflurane anesthesia-mediated oxidative stress and cognitive impairment in hippocampal neurons of old rats can be ameliorated by expression of brain derived neurotrophic factor. |
2021-04-19 |
2023-08-13 |
rat |