| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samantha Scarola, Molly Kent, Steven Neal, Jose Perdomo Trejo, Massimo Bardi, Kelly Lamber. Postpartum environmental challenges alter maternal responsiveness and offspring development. Hormones and behavior. vol 122. 2021-03-23. PMID:32330549. |
for neurobiological measures of stress/resilience responsiveness, fecal samples were collected for detection of corticosterone and dhea metabolites; additionally, immunohistochemistry was conducted on the maternal brains to indicate the presence of neuropeptide y (npy) and brain derived neurotrophic factor (bdnf) immunoreactivity in the hippocampus, amygdala and hypothalamus. |
2021-03-23 |
2023-08-13 |
rat |
| William H Walker, Jeremy C Borniger, Monica M Gaudier-Diaz, O Hecmarie Meléndez-Fernández, Jordan L Pascoe, A Courtney DeVries, Randy J Nelso. Acute exposure to low-level light at night is sufficient to induce neurological changes and depressive-like behavior. Molecular psychiatry. vol 25. issue 5. 2021-03-16. PMID:31138889. |
lan was associated with reduced hippocampal vascular endothelial growth factor-a (vegf-a) in both male and female mice, as well as increased vegfr1 and interleukin-1β mrna expression in females, and reduced brain derived neurotrophic factor mrna in males. |
2021-03-16 |
2023-08-13 |
mouse |
| Qian Zhou, Ayumi Suzuki, Mitsuo Iinuma, Ke-Yong Wang, Kin-Ya Kubo, Kagaku Azum. Effects of Maternal Chewing on Prenatal Stress-Induced Cognitive Impairments in the Offspring via Multiple Molecular Pathways. International journal of molecular sciences. vol 21. issue 16. 2021-02-18. PMID:32781547. |
immunohistochemistry and western blot findings revealed that maternal chewing alleviated hippocampal neurogenesis impairment and increased the expression of hippocampal brain-derived neurotrophic factor in the offspring. |
2021-02-18 |
2023-08-13 |
mouse |
| Ying Li, Huahui Lu, Shangjin Xie, Ying Cong, Ying Wang, Maoshu Zhu, Juan Zho. Propane-2-sulfonic acid octadec-9-enyl-amide alleviates scopolamine-induced spatial learning and memory deficits in mice. Biochemical and biophysical research communications. vol 529. issue 2. 2021-02-12. PMID:32703424. |
n15 pretreatment also significantly increased the expression levels of growth-associated protein-43, synaptophysin, brain-derived neurotrophic factor and neurotrophin-3 in the hippocampus. |
2021-02-12 |
2023-08-13 |
mouse |
| Yi-Zhi Ren, Ben-Zheng Zhang, Xiao-Jing Zhao, Zhi-Yuan Zhan. Resolvin D1 ameliorates cognitive impairment following traumatic brain injury via protecting astrocytic mitochondria. Journal of neurochemistry. vol 154. issue 5. 2021-02-04. PMID:31951012. |
meanwhile, rvd1 was also shown to increase the expression of brain-derived neurotrophic factor and glutamate aspartate transporter in the hippocampus following tbi, which indicates a possible way by which rvd1 increases the supportive function of astrocytes. |
2021-02-04 |
2023-08-13 |
mouse |
| Cong-Rong Tang, Xu-Ben Yu, Hai-Na Zhang, Yan-Cheng Cao, Fan Yang, Lei-Mei Xu, Ruo-Lan Sun, Zi Ye, Ye-Xuan Wang, Jin Lian. Lovastatin Prevents Depressive Behaviors and Increased Hippocampal Neurogenesis in Streptozotocin-Induced Diabetic Mice. Pharmacology. vol 105. issue 5-6. 2021-02-03. PMID:31722363. |
the study further showed that these treatments improved the hippocampal neurogenesis as evidenced by increased bromodeoxyuridine-positive cells in the dentate gyrus with higher expression of mature brain-derived neurotrophic factor and increased phosphorylation of camp-response element-binding protein. |
2021-02-03 |
2023-08-13 |
mouse |
| Gabriele C Pereira, Karine Roversi, Gabriela Trevisan, Marilise E Burger, Guilherme V Boch. Glucocorticoid and brain-derived neurotrophic factor relationship: a brief investigation into the model of depression by chronic administration of corticosterone. Behavioural pharmacology. vol 31. issue 4. 2021-01-29. PMID:32040016. |
moreover, the glucocorticoid receptor and tyrosine-receptor kinase b expression were increased in the hippocampus while the brain-derived neurotrophic factor expression was reduced in the prefrontal cortex. |
2021-01-29 |
2023-08-13 |
mouse |
| Lindsay Ferguson, Christopher C Giza, Rebecka O Serpa, Tiffany Greco, Michael Folkerts, Mayumi L Prin. Recovery From Repeat Mild Traumatic Brain Injury in Adolescent Rats Is Dependent on Pre-injury Activity State. Frontiers in neurology. vol 11. 2021-01-26. PMID:33488505. |
protein expression of brain derived neurotrophic factor (bdnf) and proliferator-activated gamma coactivator 1-alpha (pgc1α) was measured in the parietal cortex, hippocampus, and gastrocnemius muscle. |
2021-01-26 |
2023-08-13 |
rat |
| Rodrigo Moreno Klein, Camila Rigobello, Camila Borecki Vidigal, Kawane Fabrício Moura, Décio Sabbatini Barbosa, Daniela Cristina Ceccatto Gerardin, Graziela Scalianti Ceravolo, Estefânia Gastaldello Moreir. Gestational exposure to paracetamol in rats induces neurofunctional alterations in the progeny. Neurotoxicology and teratology. vol 77. 2021-01-25. PMID:31644948. |
moreover, lipid hidroperoxide (looh), reduced glutathione (gsh) and brain derived neurotrophic factor (bdnf) levels were quantified in prefrontal cortex and hippocampus of 22-days-old rats. |
2021-01-25 |
2023-08-13 |
rat |
| Dai Nogimura, Takafumi Mizushige, Yuki Taga, Akitoshi Nagai, Sayo Shoji, Nao Azuma, Masashi Kusubata, Shin-Ichi Adachi, Fumiaki Yoshizawa, Yukihito Kabuyam. Prolyl-hydroxyproline, a collagen-derived dipeptide, enhances hippocampal cell proliferation, which leads to antidepressant-like effects in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 4. 2021-01-19. PMID:32115749. |
po significantly increased the gene expression of brain-derived neurotrophic factor and nerve growth factor in the hippocampus, and promoted the proliferation of neural progenitor cells in vivo and in vitro. |
2021-01-19 |
2023-08-13 |
mouse |
| YunLei Wang, YuGe Zhang, WenZhu Wang, Xu Liu, YaFei Chi, JianFeng Lei, BaoGui Zhang, Tong Zhan. Effects of circadian rhythm disorder on the hippocampus of SHR and WKY rats. Neurobiology of learning and memory. vol 168. 2021-01-13. PMID:31857218. |
crd and hypertension decreased fractional anisotropy values, the number of neurons and astrocytes in the hippocampus, and the expression of brain-derived neurotrophic factor and synapsin 1; it also enhanced the degeneration of neurons and microglia and reduced blood flow in the hippocampus, and increased nuclear factor κb, caspase, neuron-specific enolase, and interleukin-6 levels. |
2021-01-13 |
2023-08-13 |
rat |
| Atsushi Toyoda, Takahiro Kawase, Takamitsu Tsukahar. Effects of dietary intake of heat-inactivated Lactobacillus gasseri CP2305 on stress-induced behavioral and molecular changes in a subchronic and mild social defeat stress mouse model. Biomedical research (Tokyo, Japan). vol 41. issue 2. 2021-01-04. PMID:32307337. |
scsds did not alter the gene expression of brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 in the hippocampus. |
2021-01-04 |
2023-08-13 |
mouse |
| Rachel Anne Hill, Adrienne Mary Grech, Michael J Notaras, Mauricio Sepulveda, Maarten van den Buus. Brain-Derived Neurotrophic Factor Val66Met polymorphism interacts with adolescent stress to alter hippocampal interneuron density and dendritic morphology in mice. Neurobiology of stress. vol 13. 2020-12-22. PMID:33344708. |
brain-derived neurotrophic factor val66met polymorphism interacts with adolescent stress to alter hippocampal interneuron density and dendritic morphology in mice. |
2020-12-22 |
2023-08-13 |
mouse |
| Ashok Jangra, Prabha Rajput, Durgesh Kumar Dwivedi, Mangala Lahka. Amelioration of Repeated Restraint Stress-Induced Behavioral Deficits and Hippocampal Anomalies with Taurine Treatment in Mice. Neurochemical research. vol 45. issue 4. 2020-12-11. PMID:31898086. |
using western blotting analyses, we demonstrate that taurine treatment significantly ameliorated the alterations in brain-derived neurotrophic factor, caspase-3, and nuclear factor kappa-light-chain-enhancer of activated b cells (nf-κb) level in the hippocampus. |
2020-12-11 |
2023-08-13 |
mouse |
| Salina Akter, Kazi Rasel Uddin, Hiroyuki Sasaki, Yijin Lyu, Shigenobu Shibat. Gamma oryzanol impairs alcohol-induced anxiety-like behavior in mice via upregulation of central monoamines associated with Bdnf and Il-1β signaling. Scientific reports. vol 10. issue 1. 2020-12-08. PMID:32606350. |
the significant elevation and reduction in the hippocampus of relative mrna levels of brain-derived neurotrophic factor and interleukin 1β, respectively, also showed the neuroprotective role of gorz in ethanol-induced anxiety. |
2020-12-08 |
2023-08-13 |
mouse |
| Chong-Su Kim, Woo Young Chun, Dong-Mi Shi. Dehydration Impairs Physical Growth and Cognitive Development in Young Mice. Nutrients. vol 12. issue 3. 2020-12-07. PMID:32121420. |
moreover, dehydration significantly dysregulated long-term potentiation signaling and specifically decreased hippocampal brain-derived neurotrophic factor |
2020-12-07 |
2023-08-13 |
mouse |
| Zuntao Wu, Lin Bai, Runqi Tu, Lijie Zhang, Yue Ba, Huizhen Zhang, Xing Li, Xuemin Cheng, Wenjie Li, Hui Huan. Disruption of synaptic expression pattern and age-related DNA oxidation in a neuronal model of lead-induced toxicity. Environmental toxicology and pharmacology. vol 76. 2020-12-04. PMID:32058320. |
in the hippocampus of lead exposed mice at three age nodes, the expression of brain-derived neurotrophic factor precursor (probdnf) increased, while that of mature bdnf (mbdnf), camp-response element binding protein (creb) and phosphorylated creb (pcreb) decreased compared with the control group. |
2020-12-04 |
2023-08-13 |
mouse |
| Ning Jiang, Haixia Wang, Jingwei Lv, Qiong Wang, Cong Lu, Yujiao Li, Xinmin Li. Dammarane sapogenins attenuates stress-induced anxiety-like behaviors by upregulating ERK/CREB/BDNF pathways. Phytotherapy research : PTR. vol 34. issue 10. 2020-11-30. PMID:32431006. |
treatment with ds significantly upregulated bdnf (brain-derived neurotrophic factor), p-creb/creb and p-erk1/2/erk1/2 protein expression in the hippocampus and prefrontal cortex of csds mice. |
2020-11-30 |
2023-08-13 |
mouse |
| Mercedes Rose, Alain Filiatreault, Josée Guénette, Andrew Williams, Errol M Thomso. Ozone increases plasma kynurenine-tryptophan ratio and impacts hippocampal serotonin receptor and neurotrophic factor expression: Role of stress hormones. Environmental research. vol 185. 2020-11-20. PMID:32278163. |
hippocampal expression of serotonin receptors exhibited differential regulation following exposure, and expression of key neurotrophic factors (brain-derived neurotrophic factor, vascular endothelial growth factor a, insulin-like growth factor-1, tyrosine kinase receptor b, b-cell lymphoma 2) was decreased. |
2020-11-20 |
2023-08-13 |
rat |
| Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. |
brain derived neurotrophic factor (bdnf), synaptophysin, and tau hyperphosphorylation (t396) in the hippocampus were also examined. |
2020-11-17 |
2023-08-13 |
mouse |