All Relations between fatty acid amide hydrolase and cannabinoids

Reference Sentence Publish Date Extraction Date Species
Shrouq I Farah, Samantha Hilston, Ngan Tran, Nikolai Zvonok, Alexandros Makriyanni. 1-, 2- and 3-AG as substrates of the endocannabinoid enzymes and endogenous ligands of the cannabinoid receptor 1. Biochemical and biophysical research communications vol 591 issue 2022 34995983 Here, we present the interaction profiles of 2-AG and its isomerization products, 1- and 3-AG, with the endocannabinoid MGL, ABHD6 and FAAH enzymes as well as the CB1 receptor. 2022-01-07 2022-01-09 Not clear
Subramaniam Jayanthi, Ritvik Peesapati, Michael T McCoy, Bruce Ladenheim, Jean Lud Cade. Footshock-Induced Abstinence from Compulsive Methamphetamine Self-administration in Rat Model Is Accompanied by Increased Hippocampal Expression of Cannabinoid Receptors (CB1 and CB2). Molecular neurobiology vol issue 2022 34978045 Animals were euthanized 2\xc2\xa0h after the last METH SA session and their hippocampi were used to measure mRNA levels of cannabinoid receptors (CB/Cnr), as well as those of synthesizing (DAGL-A, DAGL-B, NAPEPLD) and metabolizing (MGLL, FAAH, PTGS2) enzymes of the endocannabinoid cascade. 2022-01-03 2022-01-08 rat
F M Filbey, D Beaton, S Prasha. The contributions of the endocannabinoid system and stress on the neural processing of reward stimuli. Progress in neuro-psychopharmacology & biological psychiatry vol 106 issue 2021 33221340 Specifically, a single nucleotide polymorphism (SNP) variant in the cannabinoid receptor 1 (CNR1) gene, early life stress, and current perceived stress modulated reward responsivity in long-term, heavy cannabis users, while a variant in the fatty acid amide hydrolase (FAAH) gene and current perceived stress modulated cue-elicited response in non-using controls. 2021-12-31 2022-01-08 Not clear
Reshed Abohalaka, Turgut Emrah Bozkurt, Tuba Re\\xc3\\xa7ber, Sevgen Celik Onder, Emirhan Nemutlu, Sedef K\\xc4\\xb1r, Inci Sahin-Erdeml. The effects of systemic and local fatty acid amide hydrolase and monoacylglycerol lipase inhibitor treatments on the metabolomic profile of lungs. Biomedical chromatography : BMC vol 36 issue 1 2021 34449902 Previously, we have shown that increasing the tissue endocannabinoid levels by fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibitors can prevent airway inflammation and hyperreactivity. 2021-12-30 2022-01-08 mouse
Stacey Herriage, Guangping Chen, Carey Pop. Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells. Toxicology in vitro : an international journal published in association with BIBRA vol 78 issue 2021 34756920 AChE is critical in regulating cholinergic signaling while FAAH catalyzes the inactivation of fatty acid signaling lipids including the endocannabinoid (eCB) N-arachidonylethanolamine (anandamide, AEA) and eCB-like metabolites (e.g., oleoylethanolamide, OEA). 2021-12-27 2022-01-08 Not clear
Smita Jain, Akansha Bisht, Kanika Verma, Swarnima Negi, Sarvesh Paliwal, Swapnil Sharm. The role of fatty acid amide hydrolase enzyme inhibitors in Alzheimer's disease. Cell biochemistry and function vol issue 2021 34931308 Fatty acid amide hydrolase (FAAH) is a prominent enzyme of the endocannabinoid system that degrades endogenous cannabinoid anandamide and oleamide. 2021-12-21 2022-01-08 Not clear
Karla Chavira-Ramos, Mario Orozco-Morales, \\xc3\\x87imen Karasu, Alexey A Tinkov, Michael Aschner, Abel Santamar\\xc3\\xada, Ana Laura Col\\xc3\\xadn-Gonz\\xc3\\xa1le. URB597 Prevents the Short-Term Excitotoxic Cell Damage in Rat Cortical Slices: Role of Cannabinoid 1 Receptors. Neurotoxicity research vol 39 issue 2 2021 33141426 The effects of URB597, an inhibitor of the fatty acid amide hydrolase (FAAH), were tested against the quinolinic acid (QUIN)-induced early toxic effects in rat cortical slices, and compared with those effects exerted by the endocannabinoid anandamide (AEA). 2021-12-10 2022-01-08 Not clear
Duncan G J Green, Jinhee Kim, Stephen J Kish, Rachel F Tyndale, Matthew N Hill, Antonio P Strafella, Junchao Tong, Tina McCluskey, Duncan J Westwood, Sylvain Houle, Nancy J Lobaugh, Isabelle Boilea. Fatty acid amide hydrolase binding is inversely correlated with amygdalar functional connectivity: a combined positron emission tomography and magnetic resonance imaging study in healthy individuals. Journal of psychiatry & neuroscience : JPN vol 46 issue 2 2021 33729738 Upregulation of the endocannabinoid enzyme fatty acid amide hydrolase (FAAH) has been linked to abnormal activity in frontoamygdalar circuits, a hallmark of posttraumatic stress disorder. 2021-12-08 2022-01-08 Not clear
Sarah Rieck, Sofia Kilgus, Johanna H Meyer, Hao Huang, Lan Zhao, Michaela Matthey, Xin Wang, Steffen Schmitz-Valckenberg, Bernd K Fleischmann, Daniela Wenze. Inhibition of Vascular Growth by Modulation of the Anandamide/Fatty Acid Amide Hydrolase Axis. Arteriosclerosis, thrombosis, and vascular biology vol 41 issue 12 2021 34615374 Approach and Results: Here, we show that inactivation of FAAH (fatty acid amide hydrolase), the enzyme responsible for degradation of the endocannabinoid anandamide, strongly impairs angiogenesis in vitro and in vivo. 2021-12-08 2022-01-08 Not clear
Maya R Jacobson, Jeremy J Watts, Tania Da Silva, Rachel F Tyndale, Pablo M Rusjan, Sylvain Houle, Alan A Wilson, Ruth A Ross, Isabelle Boileau, Romina Mizrah. Fatty acid amide hydrolase is lower in young cannabis users. Addiction biology vol 26 issue 1 2021 31960544 We have recently shown that levels of fatty acid amide hydrolase (FAAH), the enzyme that metabolizes the endocannabinoid anandamide, are lower in the brains of adult cannabis users (CUs) (34 \xc2\xb1 11 years of age), tested during early abstinence. 2021-10-05 2022-01-08 human
Mauro Maccarrone, Valeria Gasperi, Filomena Fezza, Alessandro Finazzi-Agr\\xc3\\xb2, Antonello Ross. Differential regulation of fatty acid amide hydrolase promoter in human immune cells and neuronal cells by leptin and progesterone. European journal of biochemistry vol 271 issue 23-24 2005 15606754 Unlike FAAH, the other proteins of the endocannabinoid system are not modulated by the two hormones. 2005-07-06 2022-01-08 Not clear
S Yazulla, K M Studholme, H H McIntosh, D G Deutsc. Immunocytochemical localization of cannabinoid CB1 receptor and fatty acid amide hydrolase in rat retina. The Journal of comparative neurology vol 415 issue 1 1999 10540359 Immunocytochemical methods were used to localize cannabinoid CB1 receptor immunoreactivity (CB1R-IR) and an endocannabinoid (anandamide and 2-arachidonylglycerol) degradative enzyme, fatty acid amide hydrolase (FAAH)-IR, in the rat retina. 1999-12-02 2022-01-08 Not clear
K Tsou, M I Nogueron, S Muthian, M C Sa\\xc3\\xb1udo-Pena, C J Hillard, D G Deutsch, J M Walke. Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry. Neuroscience letters vol 254 issue 3 1999 10214976 These data demonstrate that FAAH is heterogeneously distributed and this distribution exhibits considerable, although not complete, overlap with the distribution of cannabinoid CB1 receptors in rat brain. 1999-06-22 2022-01-08 Not clear
K Tsou, M I Nogueron, S Muthian, M C Sa\\xc3\\xb1udo-Pena, C J Hillard, D G Deutsch, J M Walke. Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry. Neuroscience letters vol 254 issue 3 1999 10214976 The distribution in the rat brain of fatty acid amide hydrolase (FAAH) an enzyme that catalyzes the hydrolysis of the endogenous cannabinoid anandamide was studied by immunohistochemistry. 1999-06-22 2022-01-08 Not clear
D L Boger, S J Henriksen, B F Cravat. Oleamide: an endogenous sleep-inducing lipid and prototypical member of a new class of biological signaling molecules. Current pharmaceutical design vol 4 issue 4 1999 10197045 The characterization, cloning, and neuronal distribution of FAAH have been detailed and the enzyme was found to possess the ability to hydrolyze a range of fatty acid amides including anandamide which serves as the endogenous ligand for the cannabinoid receptor. 1999-05-10 2022-01-08 Not clear
M Egertov\\xc3\\xa1, D K Giang, B F Cravatt, M R Elphic. A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain. Proceedings. Biological sciences vol 265 issue 1410 1998 9842734 High concentrations of FAAH activity were detected in the cerebellum, hippocampus and neocortex, regions of the rat brain which are enriched with cannabinoid receptors. 1998-12-22 2022-01-08 Not clear
M Egertov\\xc3\\xa1, D K Giang, B F Cravatt, M R Elphic. A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain. Proceedings. Biological sciences vol 265 issue 1410 1998 9842734 The close correspondence in the distribution of FAAH and CB1 in rat brain and the complementary pattern of FAAH and CB1 expression at the cellular level provides important new evidence that FAAH may participate in cannabinoid signalling mechanisms of the brain. 1998-12-22 2022-01-08 Not clear
M Egertov\\xc3\\xa1, D K Giang, B F Cravatt, M R Elphic. A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain. Proceedings. Biological sciences vol 265 issue 1410 1998 9842734 Here we have analysed the distribution of FAAH in rat brain and compared its cellular localization with CB1-type cannabinoid receptors using immunocytochemistry. 1998-12-22 2022-01-08 Not clear
T Bisogno, D Melck, L De Petrocellis, Bobrov MYu, N M Gretskaya, V V Bezuglov, N Sitachitta, W H Gerwick, V Di Marz. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. Biochemical and biophysical research communications vol 248 issue 3 1998 9703957 Most FAAH blockers developed to date also inhibit cytosolic phospholipase A2 (cPLA2) and/or bind to the CB1 cannabinoid receptor subtype. 1998-09-08 2022-01-08 mouse
T Bisogno, D Melck, L De Petrocellis, Bobrov MYu, N M Gretskaya, V V Bezuglov, N Sitachitta, W H Gerwick, V Di Marz. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. Biochemical and biophysical research communications vol 248 issue 3 1998 9703957 Fatty acid amide hydrolase (FAAH) catalyzes the hydrolysis of bioactive fatty acid amides and esters such as the endogenous cannabinoid receptor ligands, anandamide (N-arachidonoyl-ethanolamine) and 2-arachidonoylglycerol, and the putative sleep inducing factor cis-9-octadecenoamide (oleamide). 1998-09-08 2022-01-08 mouse
T Bisogno, D Melck, L De Petrocellis, Bobrov MYu, N M Gretskaya, V V Bezuglov, N Sitachitta, W H Gerwick, V Di Marz. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. Biochemical and biophysical research communications vol 248 issue 3 1998 9703957 AA-5-HT is the first FAAH inhibitor reported to date which is inactive both against cPLA2 and at CB1 receptors, whereas AEG represents a new type of cannabinoid receptor agonist. 1998-09-08 2022-01-08 mouse
T Bisogno, N Sepe, L De Petrocellis, R Mechoulam, V Di Marz. The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. Biochemical and biophysical research communications vol 239 issue 2 1997 9344854 The enzyme catalyzing the hydrolysis of the amide bond of oleamide as well as of anandamide, the putative endogenous ligand of cannabinoid receptors, was purified from rat liver, cloned, shown to be expressed also in brain and named fatty acid amide hydrolase (FAAH). 1997-11-17 2022-01-08 rat
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