All Relations between microtubule-associated protein tau and neuroglial cell

Reference Sentence Publish Date Extraction Date Species
Shanshan Ma, Xinkui Zhou, Yaping Wang, Zhe Li, Yingying Wang, Jijing Shi, Fangxia Gua. MG53 protein rejuvenates hUC-MSCs and facilitates their therapeutic effects in AD mice by activating Nrf2 signaling pathway. Redox biology vol 53 issue 2022 35525026 furthermore, mg53 combined with young huc-mscs transplantation alleviated cognitive deficit and depression-like behavior in ad mice, reduced a\xce\xb2 deposition and tau phosphorylation, promoted neurogenesis, and inhibited glia cells activation and oxidative stress by activating the nrf2 signaling. 2022-05-07 2022-05-09 Not clear
Chao Zhou, Wanyan Ni, Taiyang Zhu, Shuyu Dong, Ping Sun, Fang Hu. Cellular Reprogramming and Its Potential Application in Alzheimer's Disease. Frontiers in neuroscience vol 16 issue 2022 35464309 extracellular amyloid-beta deposition, intracellular tau hyperphosphorylation, neuronal death, glial cell activation, white matter damage, blood-brain barrier disruption, and other mechanisms all take part in this complicated disease, making it difficult to find an effective therapy. 2022-04-25 2022-04-26 Not clear
Marta Caama\\xc3\\xb1o-Moreno, Ricardo Gargin. Tauopathies: the role of tau in cellular crosstalk and synaptic dysfunctions. Neuroscience vol issue 2022 35272005 all of them are characterized by aberrant aggregation of tau protein in neurons and glia that are distributed in different brain regions according to their susceptibility. 2022-03-10 2022-04-14 Not clear
Marta Caama\\xc3\\xb1o-Moreno, Ricardo Gargin. Tauopathies: the role of tau in cellular crosstalk and synaptic dysfunctions. Neuroscience vol issue 2022 35272005 in this way, this review shows how tau inclusions in glia influence the synaptic dysfunctions that result in the cognitive symptoms characteristic of tauopathies. 2022-03-10 2022-04-14 Not clear
Juan R Perea, Esther Garc\\xc3\\xada, Laura Vall\\xc3\\xa9s-Saiz, Raquel Cuadros, F\\xc3\\xa9lix Hern\\xc3\\xa1ndez, Marta Bol\\xc3\\xb3s, Jes\\xc3\\xbas Avil. p38 activation occurs mainly in microglia in the P301S Tauopathy mouse model. Scientific reports vol 12 issue 1 2022 35136118 although this kinase is expressed mainly in glia, its activation in certain neurodegenerative diseases such as alzheimer's disease has been associated with its ability to phosphorylate tau in neurons. 2022-02-09 2022-02-10 Not clear
Chijioke Akunwafo, Jeiran Choupan, Farshid Sepehrban. Premortem perivascular space morphology is a predictor of postmortem glia tau pathology in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association vol 17 Suppl 3 issue 2022 35109135 premortem perivascular space morphology is a predictor of postmortem glia tau pathology in alzheimer's disease. 2022-02-03 2022-02-06 Not clear
Mennatallah O Zaki, Doaa A Elsherbiny, Mohamed Salama, Samar S Aza. Potential role of Drug Repositioning Strategy (DRS) for management of tauopathy. Life sciences vol issue 2022 34974076 tauopathy is a term that has been used to represent a pathological condition in which hyperphosphorylated tau protein aggregates in neurons and glia which results in neurodegeneration, synapse loss and dysfunction and cognitive impairments. 2022-01-27 2022-01-13 Not clear
Ashlyn G Johnson, James A Webster, Chadwick M Hale. Glial profiling of human tauopathy brain demonstrates enrichment of astrocytic transcripts in tau-related frontotemporal degeneration. Neurobiology of aging vol 112 issue 2022 35051675 to understand how glia may be altered in frontotemporal degeneration with tau pathology (ftd-tau), we used a nanostring glial profiling panel to measure 770 transcripts related to glial biology in human control (n\xc2\xa0=\xc2\xa08), alzheimer's disease (ad) (n\xc2\xa0=\xc2\xa08), and ftd-tau (n\xc2\xa0=\xc2\xa08) dorsolateral prefrontal cortex. 2022-01-20 2022-01-27 Not clear
Mennatallah O Zaki, Doaa A Elsherbiny, Mohamed Salama, Samar S Aza. Potential role of Drug Repositioning Strategy (DRS) for management of tauopathy. Life sciences vol issue 2022 34974076 tauopathy is a term that has been used to represent a pathological condition in which hyperphosphorylated tau protein aggregates in neurons and glia which results in neurodegeneration, synapse loss and dysfunction and cognitive impairments. 2022-01-02 2022-01-13 Not clear
YouJin Lee, Morgan R Miller, Marty A Fernandez, Elizabeth L Berg, Adriana M Prada, Qing Ouyang, Michael Schmidt, Jill L Silverman, Tracy L Young-Pearse, Eric M Morro. Early lysosome defects precede neurodegeneration with amyloid-\\xce\\xb2 and tau aggregation in NHE6-null rat brain. Brain : a journal of neurology vol issue 2021 34928329 interestingly, we observe tau deposition in both neurons and glia, as has been reported in cs postmortem studies previously. 2021-12-20 2022-01-13 Not clear
Aviva M Tolkovsky, Maria Grazia Spillantin. Tau aggregation and its relation to selected forms of neuronal cell death. Essays in biochemistry vol issue 2021 34897457 although alzheimer's disease (ad) is the most prevalent tauopathy, tauopathies comprise an array of over 30 diseases in which the cytoplasmic protein tau aggregates in neurons, and also, in some diseases, in glia. 2021-12-13 2022-01-13 Not clear
Barbara E Stopschinski, Kelly Del Tredici, Sandi-Jo Estill-Terpack, Estifanos Ghebremdehin, Fang F Yu, Heiko Braak, Marc I Diamon. Anatomic survey of seeding in Alzheimer's disease brains reveals unexpected patterns. Acta neuropathologica communications vol 9 issue 1 2021 34635189 at8 staining in brain regions identified because of tau seeding also revealed pathology in a previously undescribed cell type: bergmann glia of the cerebellar cortex. 2021-11-05 2022-01-13 Not clear
Alexander Sandberg, Helen Ling, Marla Gearing, Beth Dombroski, Laura Cantwell, Lea R'Bibo, Allan Levey, Gerard D Schellenberg, John Hardy, Nicholas Wood, Josefin Fernius, Sofie Nystr\\xc3\\xb6m, Samuel Svensson, Stefan Thor, Per Hammarstr\\xc3\\xb6m, Tamas Revesz, Kin Y Mo. Fibrillation and molecular characteristics are coherent with clinical and pathological features of 4-repeat tauopathy caused by MAPT variant G273R. Neurobiology of disease vol 146 issue 2021 32961270 we herein return to pathological examination which demonstrated tau immunoreactivity in neurons and glia consistent of mixed progressive supranuclear palsy (psp) and corticobasal degeneration (cbd) features. 2021-10-25 2022-01-13 Not clear
Hallie Morton, Sudhir Kshirsagar, Erika Orlov, Lloyd E Bunquin, Neha Sawant, Lauren Boleng, Mathew George, Tanisha Basu, Bhagavathi Ramasubramanian, Jangampalli Adi Pradeepkiran, Subodh Kumar, Murali Vijayan, Arubala P Reddy, P Hemachandra Redd. Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse. Free radical biology & medicine vol 172 issue 2021 34246776 ad is marked by multiple cellular changes, including deregulation of micrornas, activation of glia and astrocytes, hormonal imbalance, defective mitophagy, synaptic degeneration, in addition to extracellular neuritic amyloid-beta (a\xce\xb2) plaques, phosphorylated tau (p-tau), and intracellular neurofibrillary tangles (nfts). 2021-08-19 2022-01-13 Not clear
Jonathan D Cherry, Soong Ho Kim, Thor D Stein, Morgan J Pothast, Raymond Nicks, Gaoyuan Meng, Bertrand R Huber, Jesse Mez, Michael L Alosco, Yorghos Tripodis, Kurt Farrell, Victor E Alvarez, Ann C McKee, John F Crar. Evolution of neuronal and glial tau isoforms in chronic traumatic encephalopathy. Brain pathology (Zurich, Switzerland) vol 30 issue 5 2021 32500646 chronic traumatic encephalopathy (cte) is a neurodegenerative tauopathy characterized by accumulation of hyperphosphorylated tau (p-tau) in perivascular aggregates in neurons and glia at the depths of neocortical sulci and progresses to diffuse neocortical, allocortical and brainstem structures. 2021-08-16 2022-01-13 Not clear
M Verny, C Duyckaert. Cognitive deficit, and neuropathological correlates, in the oldest-old. Revue neurologique vol 176 issue 9 2021 32178879 tau inclusions in cortical glia have also been shown to participate to the intellectual deficit. 2021-07-29 2022-01-13 Not clear
Susan C Schwerin, Mitali Chatterjee, Elizabeth B Hutchinson, Francis T Djankpa, Regina C Armstrong, Joseph T McCabe, Daniel P Perl, Sharon L Julian. Expression of GFAP and Tau Following Blast Exposure in the Cerebral Cortex of Ferrets. Journal of neuropathology and experimental neurology vol 80 issue 2 2021 33421075 in this study, ferrets received compressed air shock waves and subsequent evaluation of glia and forms of tau following survival of up to 12\xe2\x80\x89weeks. 2021-06-22 2022-01-13 Not clear
Guilherme Lopes Dornelles, Juliana Sorraila de Oliveira, Erin John Rieger de Almeida, Camila Benaduce Emanuelli Mello, Bernardo Rodrigues E Rodrigues, C\\xc3\\xa1ssia Bagolin da Silva, Let\\xc3\\xadcia Dos Santos Petry, Micheli Mainardi Pillat, Ta\\xc3\\xads Vidal Palma, Cinthia Melazzo de Andrad. Ellagic Acid Inhibits Neuroinflammation and Cognitive Impairment Induced by Lipopolysaccharides. Neurochemical research vol 45 issue 10 2021 32779097 the present study investigated the effects of ellagic acid in the object recognition test, oxidative stress, cholinergic neurotransmission, glial cell expression, and phosphorylated tau protein expression. 2021-06-01 2022-01-13 Not clear
Guilherme Lopes Dornelles, Juliana Sorraila de Oliveira, Erin John Rieger de Almeida, Camila Benaduce Emanuelli Mello, Bernardo Rodrigues E Rodrigues, C\\xc3\\xa1ssia Bagolin da Silva, Let\\xc3\\xadcia Dos Santos Petry, Micheli Mainardi Pillat, Ta\\xc3\\xads Vidal Palma, Cinthia Melazzo de Andrad. Ellagic Acid Inhibits Neuroinflammation and Cognitive Impairment Induced by Lipopolysaccharides. Neurochemical research vol 45 issue 10 2021 32779097 the results showed that the treatment with ea in the lps group was able to inhibit cognitive impairment, modulate the immune system response by significantly reducing glial cell expression, attenuating phosphorylated tau and oxidative damage with consequent improvement in the antioxidant system, as well as preventing the increase of acetylcholinesterase activity. 2021-06-01 2022-01-13 Not clear
Hariharakrishnan Chidambaram, Subashchandrabose Chinnathamb. G-Protein Coupled Receptors and Tau-different Roles in Alzheimer's Disease. Neuroscience vol 438 issue 2021 32335218 tau aggregates undergo trans-cellular propagation by the release of fibrillar species into the extra-cellular environment from damaged and infected neurons that can be internalized by neighbouring neuronal and glia cells and promotes aggregation in healthy cells. 2021-05-14 2022-01-13 Not clear
Page: 
1   2   3   4   5   6   7