All Relations between microtubule-associated protein tau and hippocampus

Publication Sentence Publish Date Extraction Date Species
Qing Tao, Xianhe Wang, Lei Liu, Yongsheng Ji, Qingli Luo, Jian Du, Li Yu, Jilong Shen, Deyong Ch. Toxoplasma gondii Chinese I genotype Wh6 strain infection induces tau phosphorylation via activating GSK3β and causes hippocampal neuron apoptosis. Acta tropica. vol 210. 2020-12-17. PMID:32492398. toxoplasma gondii chinese i genotype wh6 strain infection induces tau phosphorylation via activating gsk3β and causes hippocampal neuron apoptosis. 2020-12-17 2023-08-13 mouse
Qing Tao, Xianhe Wang, Lei Liu, Yongsheng Ji, Qingli Luo, Jian Du, Li Yu, Jilong Shen, Deyong Ch. Toxoplasma gondii Chinese I genotype Wh6 strain infection induces tau phosphorylation via activating GSK3β and causes hippocampal neuron apoptosis. Acta tropica. vol 210. 2020-12-17. PMID:32492398. then we observed the formation of tissue cysts in the brain, the damage of neuron and the increased expression of phosphorylated tau (p-tau) in the hippocampal tissue of the mice. 2020-12-17 2023-08-13 mouse
Qing Tao, Xianhe Wang, Lei Liu, Yongsheng Ji, Qingli Luo, Jian Du, Li Yu, Jilong Shen, Deyong Ch. Toxoplasma gondii Chinese I genotype Wh6 strain infection induces tau phosphorylation via activating GSK3β and causes hippocampal neuron apoptosis. Acta tropica. vol 210. 2020-12-17. PMID:32492398. in all, our results indicated that tgctwh6 infection not only led to phosphorylation of tau via activating gsk3β but also promoted hippocampal neuron apoptosis. 2020-12-17 2023-08-13 mouse
Juliana C S Chaves, Felippe T Machado, Michael F Almeida, Tatiana B Bacovsky, Merari F R Ferrar. microRNAs expression correlates with levels of APP, DYRK1A, hyperphosphorylated Tau and BDNF in the hippocampus of a mouse model for Down syndrome during ageing. Neuroscience letters. vol 714. 2020-12-07. PMID:31605772. micrornas expression correlates with levels of app, dyrk1a, hyperphosphorylated tau and bdnf in the hippocampus of a mouse model for down syndrome during ageing. 2020-12-07 2023-08-13 mouse
Juliana C S Chaves, Felippe T Machado, Michael F Almeida, Tatiana B Bacovsky, Merari F R Ferrar. microRNAs expression correlates with levels of APP, DYRK1A, hyperphosphorylated Tau and BDNF in the hippocampus of a mouse model for Down syndrome during ageing. Neuroscience letters. vol 714. 2020-12-07. PMID:31605772. in this study, we investigated the association among mirnas mir-17, -20a, -101, -106b, -199b, -26a, 26b and some of their target mrnas such as app, dyrk1a and bdnf, as well as the levels of hyperphosphorylated tau in the hippocampus of a 2 and 5 months old mice model of trisomy 21 (ts65dn). 2020-12-07 2023-08-13 mouse
Tong-Yao Hou, Yang Zhou, Ling-Shuang Zhu, Xiong Wang, Pei Pang, Ding-Qi Wang, Zhen-Yu Liuyang, Hengye Man, Youming Lu, Ling-Qiang Zhu, Dan Li. Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease. Journal of neurochemistry. vol 154. issue 4. 2020-12-07. PMID:31951013. we found that artificially replicating the abnormalities in mir-124/ptpn1 signaling induced ad-like tau pathology in the hippocampus of wild-type mice, including hyperphosphorylation at multiple sites, insolubility and somadendritic aggregation, as well as learning/memory deficits. 2020-12-07 2023-08-13 mouse
Teodora Petrova, Camila Orellana, Vesna Jelic, Anne-Rita Oeksengaard, Jon Snaedal, Peter Høgh, Birgitte Bo Andersen, Mala Naik, Knut Engedal, Lars-Olof Wahlund, Daniel Ferreir. Cholinergic dysfunction, neurodegeneration, and amyloid-beta pathology in neurodegenerative diseases. Psychiatry research. Neuroimaging. vol 302. 2020-12-07. PMID:32505903. we investigated the association between the eeg-ach index and cerebrospinal fluid (csf) amyloid-beta, csf total tau, cortical thickness, and hippocampal volume from magnetic resonance imaging (mri), and cognition. 2020-12-07 2023-08-13 Not clear
Teodora Petrova, Camila Orellana, Vesna Jelic, Anne-Rita Oeksengaard, Jon Snaedal, Peter Høgh, Birgitte Bo Andersen, Mala Naik, Knut Engedal, Lars-Olof Wahlund, Daniel Ferreir. Cholinergic dysfunction, neurodegeneration, and amyloid-beta pathology in neurodegenerative diseases. Psychiatry research. Neuroimaging. vol 302. 2020-12-07. PMID:32505903. cross-sectional sub-analyses based on a small sample suggests that the eeg-ach index increases the closest to ad dementia, downstream to amyloid-beta pathology, csf total tau, and hippocampal volume. 2020-12-07 2023-08-13 Not clear
Zuntao Wu, Lin Bai, Runqi Tu, Lijie Zhang, Yue Ba, Huizhen Zhang, Xing Li, Xuemin Cheng, Wenjie Li, Hui Huan. Disruption of synaptic expression pattern and age-related DNA oxidation in a neuronal model of lead-induced toxicity. Environmental toxicology and pharmacology. vol 76. 2020-12-04. PMID:32058320. furthermore, the expression of bace1 protein and tau phosphorylation level in pfc and hippocampus increased, app mrnas in pfc and prolonged induction of bace1 in hippocampus. 2020-12-04 2023-08-13 mouse
Natalia Dos Santos Tramontin, Sabrina da Silva, Rychard Arruda, Kellen Simon Ugioni, Paula Bortuluzzi Canteiro, Gustavo de Bem Silveira, Carolini Mendes, Paulo Cesar Lock Silveira, Alexandre Pastoris Mulle. Gold Nanoparticles Treatment Reverses Brain Damage in Alzheimer's Disease Model. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31612296. oa increases tau phosphorylation in the cortex and hippocampus, while aunp treatment maintained it as normal. 2020-11-25 2023-08-13 rat
Ryszard Pluta, Marzena Ułamek-Kozioł, Janusz Kocki, Jacek Bogucki, Sławomir Januszewski, Anna Bogucka-Kocka, Stanisław J Czuczwa. Expression of the Tau Protein and Amyloid Protein Precursor Processing Genes in the CA3 Area of the Hippocampus in the Ischemic Model of Alzheimer's Disease in the Rat. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31713815. expression of the tau protein and amyloid protein precursor processing genes in the ca3 area of the hippocampus in the ischemic model of alzheimer's disease in the rat. 2020-11-25 2023-08-13 rat
Ryszard Pluta, Marzena Ułamek-Kozioł, Janusz Kocki, Jacek Bogucki, Sławomir Januszewski, Anna Bogucka-Kocka, Stanisław J Czuczwa. Expression of the Tau Protein and Amyloid Protein Precursor Processing Genes in the CA3 Area of the Hippocampus in the Ischemic Model of Alzheimer's Disease in the Rat. Molecular neurobiology. vol 57. issue 2. 2020-11-25. PMID:31713815. data show that brain ischemia activates neuronal changes and death in the ca3 region of the hippocampus in a manner dependent on amyloid and tau protein, thus determining a new and important way to regulate the survival and/or death of ischemic neurons. 2020-11-25 2023-08-13 rat
Brent Aulston, Qing Liu, Michael Mante, Jazmin Florio, Robert A Rissman, Shauna H Yua. Extracellular Vesicles Isolated from Familial Alzheimer's Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain. Journal of Alzheimer's disease : JAD. vol 72. issue 2. 2020-11-17. PMID:31594233. moreover, fad ev injected hippocampi contained significantly more tau inclusions in the ca1 hippocampal neuronal field than controls. 2020-11-17 2023-08-13 mouse
Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. brain derived neurotrophic factor (bdnf), synaptophysin, and tau hyperphosphorylation (t396) in the hippocampus were also examined. 2020-11-17 2023-08-13 mouse
Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. following partial hepatectomy, the levels of phosphorylated mtor, phosphorylated 70s6k, and phosphorylated tau were all increased in the hippocampus. 2020-11-17 2023-08-13 mouse
Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wan. Autophagy Dysfunction and mTOR Hyperactivation Is Involved in Surgery: Induced Behavioral Deficits in Aged C57BL/6J Mice. Neurochemical research. vol 45. issue 2. 2020-11-17. PMID:31865521. rapamycin treatment restored autophagy function, attenuated phosphorylation of tau protein, and increased bdnf and synaptophysin expression in the hippocampus of surgical mice. 2020-11-17 2023-08-13 mouse
Mona Khalifa, Marwa M Safar, Rania M Abdelsalam, Hala F Zak. Telmisartan Protects Against Aluminum-Induced Alzheimer-like Pathological Changes in Rats. Neurotoxicity research. vol 37. issue 2. 2020-11-12. PMID:31332715. it reversed the increase in hippocampal amyloid beta protein, phosphorylated tau protein contents together with augmentation of neprilysin level, it also diminished levels of nuclear factor kappa-b, fas ligand, tumor necrosis factor-alpha, malondialdehyde, and acetylcholinesterase content.these findings show the protective action of telmisartan against ad-like pathological alterations. 2020-11-12 2023-08-13 rat
Yanchong Zhang, Feng Wu, Khalid Iqbal, Cheng-Xin Gong, Wen Hu, Fei Li. Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice. Scientific reports. vol 9. issue 1. 2020-11-10. PMID:30846870. we detected hyperphosphorylation of tau at multiple sites in ipsilateral hippocampus 6 weeks but not 7 months after cci. 2020-11-10 2023-08-13 mouse
Marzena Ułamek-Kozioł, Stanisław Jerzy Czuczwar, Sławomir Januszewski, Ryszard Plut. Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer's Disease after Ischemia-Reperfusion Brain Injury. International journal of molecular sciences. vol 21. issue 3. 2020-11-09. PMID:32019137. data show that brain ischemia activates neuronal changes and death in the hippocampus in a manner dependent on tau protein, thus determining a new and important way to regulate the survival and/or death of post-ischemic neurons. 2020-11-09 2023-08-13 Not clear
Arnaud Charil, Sergey Shcherbinin, Sudeepti Southekal, Michael D Devous, Mark Mintun, Melissa E Murray, Bradley B Miller, Adam J Schwar. Tau Subtypes of Alzheimer's Disease Determined in vivo Using Flortaucipir PET Imaging. Journal of Alzheimer's disease : JAD. vol 71. issue 3. 2020-11-05. PMID:31476153. worse performance on delayed recall was associated with increased hippocampal tau signal, and worse performance on the trail making test b-a was associated with lower values of the hippocampus to cortex ratio. 2020-11-05 2023-08-13 human