Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Pedro A Pereira, Marta Tavares, Miguel Laires, Bárbara Mota, Maria Dulce Madeira, Manuel M Paula-Barbosa, Armando Cardos. Effects of Aging and Nerve Growth Factor on Neuropeptide Expression and Cholinergic Innervation of the Rat Basolateral Amygdala. Biology. vol 13. issue 3. 2024-03-27. PMID:38534426. |
the decreased npy expression was fully reversed by the infusion of ngf in the lateral ventricle. |
2024-03-27 |
2024-03-29 |
rat |
Ernane Torres Uchoa, Paula Beatriz Marangon, Rodrigo Rorato, Silvia Graciela Ruginsk, Lucas Kniess Debarba, Jose Antunes-Rodrigues, Lucila L K Elia. Adrenalectomy impairs insulin-induced hypophagia and related hypothalamic changes. The Journal of endocrinology. vol 242. issue 2. 2020-04-06. PMID:31189132. |
this study evaluated the effects of adx on icv (lateral ventricle) injection of insulin-induced changes on food intake, mrna expression of hypothalamic neuropeptides (insulin receptor (insr), proopiomelanocortin, cocaine and amphetamine-regulated transcript (cart), agouti-related protein, neuropeptide y (npy) in the arcuate nucleus of the hypothalamus (arc), corticotrophin-releasing factor in the paraventricular nucleus of the hypothalamus) and hypothalamic protein content of insulin signaling-related molecules (insulin receptor substrate (irs) 1, protein kinase b (akt), extracellular-signal-regulated kinase (erk1/2), c-jun n-terminal kinase (jnk), protein tyrosine phosphatase-1b (ptp1b) and t cell protein tyrosine phosphatase (tcptp)) compared with sham animals, adx increased the hypothalamic content of pjnk/jnk, ptp1b and tcptp, as well as decreased mrna expression of insr, and corticosterone (b) treatment reversed these effects. |
2020-04-06 |
2023-08-13 |
rat |
Ayako Ushimura, Tadataka Tsuji, Susumu Tanaka, Mikihiko Kogo, Takashi Yamamot. Neuropeptide-Y modulates eating patterns and masticatory muscle activity in rats. Behavioural brain research. vol 278. 2015-12-15. PMID:25447304. |
the present study investigates how npy injection into the lateral ventricle modulates masticatory movements and eating behavior. |
2015-12-15 |
2023-08-13 |
rat |
J K van den Heuvel, L Eggels, A J van Rozen, M C M Luijendijk, E Fliers, A Kalsbeek, R A H Adan, S E la Fleu. Neuropeptide Y and leptin sensitivity is dependent on diet composition. Journal of neuroendocrinology. vol 26. issue 6. 2015-01-15. PMID:24698502. |
finally, we studied npy sensitivity in rats subjected to the fchfhs, fchs, fchf or chow diet for 4 weeks by measuring food intake after administration of npy or vehicle in the lateral ventricle. |
2015-01-15 |
2023-08-13 |
rat |
J K van den Heuvel, L Eggels, A J van Rozen, M C M Luijendijk, E Fliers, A Kalsbeek, R A H Adan, S E la Fleu. Neuropeptide Y and leptin sensitivity is dependent on diet composition. Journal of neuroendocrinology. vol 26. issue 6. 2015-01-15. PMID:24698502. |
lateral ventricle administration of npy resulted in higher caloric intake in fchfhs rats compared to rats on the other choice diets or rats on chow. |
2015-01-15 |
2023-08-13 |
rat |
J E Thornton, L Holcomb, S Leupen, L Kimbroug. Effects of neuropeptide Y (NPY) and NPY agonists on lordosis in the female guinea pig. Endocrine. vol 5. issue 2. 2012-10-02. PMID:21153108. |
although npy (1 μg) increased feeding behavior when it was administered to the lateral ventricle of ovariectomized (ovx) estrogen (i.e., estradiol benzoate; eb) and progesterone- (p) treated guinea pigs, it had no facilitatory effect on lordosis behavior at any of the doses tested (0.5, 1, 5, or 10μg). |
2012-10-02 |
2023-08-12 |
Not clear |
Saeko Akimoto-Takano, Chihiro Sakurai, Setsuko Kanai, Hiroko Hosoya, Minoru Ohta, Kyoko Miyasak. Differences in the appetite-stimulating effect of orexin, neuropeptide Y and ghrelin among young, adult and old rats. Neuroendocrinology. vol 82. issue 5-6. 2006-07-18. PMID:16721031. |
after a 7-day recovery period, different doses of orexin a (0.25-3 nmol), npy and ghrelin (0.03-1 nmol) were injected into the left lateral ventricle without anesthesia. |
2006-07-18 |
2023-08-12 |
rat |
M Mahmoodi, J V Gardiner, G R Asadi Karam, M Khaksari, K G Murphy, M A Ghatei, S R Bloo. Implantation of fibre encapsulated RIN 1056a cells transfected with NPY cDNA into the lateral ventricle of rats alters body weight. Regulatory peptides. vol 132. issue 1-3. 2006-06-20. PMID:16202459. |
implantation of fibre encapsulated rin 1056a cells transfected with npy cdna into the lateral ventricle of rats alters body weight. |
2006-06-20 |
2023-08-12 |
rat |
M Mahmoodi, J V Gardiner, G R Asadi Karam, M Khaksari, K G Murphy, M A Ghatei, S R Bloo. Implantation of fibre encapsulated RIN 1056a cells transfected with NPY cDNA into the lateral ventricle of rats alters body weight. Regulatory peptides. vol 132. issue 1-3. 2006-06-20. PMID:16202459. |
npy cdna transfected and untransfected control cells were encapsulated in pvdf hollow fibres to prevent tumour formation and implanted into the lateral ventricle of male wistar rats. |
2006-06-20 |
2023-08-12 |
rat |
M Mahmoodi, J V Gardiner, G R Asadi Karam, M Khaksari, K G Murphy, M A Ghatei, S R Bloo. Implantation of fibre encapsulated RIN 1056a cells transfected with NPY cDNA into the lateral ventricle of rats alters body weight. Regulatory peptides. vol 132. issue 1-3. 2006-06-20. PMID:16202459. |
our aim was to over-express bioactive npy in the lateral ventricle by implanting cells transfected with npy cdna. |
2006-06-20 |
2023-08-12 |
rat |
Annika Thorsell, Craig J Slawecki, Cindy L Ehler. Effects of neuropeptide Y and corticotropin-releasing factor on ethanol intake in Wistar rats: interaction with chronic ethanol exposure. Behavioural brain research. vol 161. issue 1. 2005-07-29. PMID:15904720. |
in the present study, the effects of administration of crf and npy into the lateral ventricle on ethanol intake in naive and ethanol-vapor-exposed wistar rats were examined. |
2005-07-29 |
2023-08-12 |
human |
Tatiana Sandoval-Guzmán, Naomi E Ranc. Central injection of senktide, an NK3 receptor agonist, or neuropeptide Y inhibits LH secretion and induces different patterns of Fos expression in the rat hypothalamus. Brain research. vol 1026. issue 2. 2005-01-31. PMID:15488494. |
saline, senktide, or npy was injected into the lateral ventricle of unanesthetized rats and serial blood samples were collected for lh radioimmunoassay. |
2005-01-31 |
2023-08-12 |
rat |
Paula D Raposinho, Thierry Pedrazzini, Richard B White, Richard D Palmiter, Michel L Auber. Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression. Endocrinology. vol 145. issue 1. 2004-01-23. PMID:14525913. |
npy infusion into the lateral ventricle of wild-type mice stimulated food intake and induced obesity over a 7-d period. |
2004-01-23 |
2023-08-12 |
mouse |
P D Raposinho, D D Pierroz, P Broqua, R B White, T Pedrazzini, M L Auber. Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism. Molecular and cellular endocrinology. vol 185. issue 1-2. 2003-03-28. PMID:11738809. |
we have previously shown that chronic infusion of npy into the lateral ventricle of normal rats produced an obesity syndrome characterized by hyperphagia, hyperinsulinism and collapse of reproductive function. |
2003-03-28 |
2023-08-12 |
mouse |
Sumit Sarkar, Ronald M Lecha. Central administration of neuropeptide Y reduces alpha-melanocyte-stimulating hormone-induced cyclic adenosine 5'-monophosphate response element binding protein (CREB) phosphorylation in pro-thyrotropin-releasing hormone neurons and increases CREB phosphorylation in corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology. vol 144. issue 1. 2003-01-17. PMID:12488356. |
npy [10 micro g in artificial csf (acsf)] was administered into the lateral ventricle i.c.v. |
2003-01-17 |
2023-08-12 |
Not clear |
Barbara Woodside, Christian Beaulé, Christine Laua. Chronic neuropeptide Y infusion during lactation suppresses pup growth and reduces the length of lactational infertility in rats. Hormones and behavior. vol 41. issue 1. 2002-05-01. PMID:11863384. |
in subsequent experiments we examined the effects of npy infusions into the lateral ventricle at doses of 6 or 20 mug/day or unilaterally into the medial preoptic area at a dose of 1 microg/day from either days 12-19 or 7-21 postpartum. |
2002-05-01 |
2023-08-12 |
rat |
T J Roberts, A Caston-Balderrama, M J Nijland, M G Ros. Central neuropeptide Y stimulates ingestive behavior and increases urine output in the ovine fetus. American journal of physiology. Endocrinology and metabolism. vol 279. issue 3. 2000-09-19. PMID:10950815. |
at t = 3 h, ovine npy (0.05 mg/kg) was administered into the lateral ventricle, and fetuses were monitored for an additional 8 h. a control study of central administration of artificial cerebral spinal fluid was performed on an alternate day. |
2000-09-19 |
2023-08-12 |
Not clear |
D P Woldbye, P J Larsen, J D Mikkelsen, K Klemp, T M Madsen, T G Bolwi. Powerful inhibition of kainic acid seizures by neuropeptide Y via Y5-like receptors. Nature medicine. vol 3. issue 7. 1997-08-04. PMID:9212103. |
we here report that npy administered into the lateral ventricle is a powerful inhibitor of motor as well as electroencephalographic (eeg) seizures induced by kainic acid. |
1997-08-04 |
2023-08-12 |
rat |
A J Sipols, D P Figlewicz, R J Seeley, M Chavez, S C Woods, D Port. Intraventricular neuropeptide Y does not stimulate food intake in the baboon. Physiology & behavior. vol 60. issue 3. 1997-01-16. PMID:8873242. |
in the present study, we examined the ability of the orexigenic peptide neuropeptide y (npy) to stimulate feeding when administered into the lateral ventricle of baboons. |
1997-01-16 |
2023-08-12 |
Not clear |
D D Pierroz, C Catzeflis, A C Aebi, J E Rivier, M L Auber. Chronic administration of neuropeptide Y into the lateral ventricle inhibits both the pituitary-testicular axis and growth hormone and insulin-like growth factor I secretion in intact adult male rats. Endocrinology. vol 137. issue 1. 1996-02-05. PMID:8536627. |
to analyze the effects of the same type of chronic npy treatment on the pituitary-testicular axis, 45-day-old sprague-dawley male rats were implanted with stainless steel cannulas in the right lateral ventricle. |
1996-02-05 |
2023-08-12 |
rat |