| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lillemor Berntson, Andreas Elfving, Alice Gabrielsson Samuelsson, Anders Öman, Fariborz Mobarre. Blood brain barrier permeability and astrocyte-derived extracellular vesicles in children with juvenile idiopathic arthritis: a cross-sectional study. Pediatric rheumatology online journal. vol 22. issue 1. 2024-04-27. PMID:38671467. |
this study investigates the potential cns involvement in jia by analyzing the presence of astrocyte-derived extracellular vesicles (evs) and the s100b protein in plasma, both of which are indicative of astrocyte activity and blood-brain barrier (bbb) integrity. |
2024-04-27 |
2024-04-29 |
Not clear |
| Jéssica Taday, Fernanda Telles Fróes, Marina Seady, Carlos Alberto Gonçalves, Marina Concli Leit. In Vitro Astroglial Dysfunction Induced by Neurotoxins: Mimicking Astrocytic Metabolic Alterations of Alzheimer's Disease. Metabolites. vol 14. issue 3. 2024-03-27. PMID:38535311. |
the dysfunction of these cells is widely associated with brain disorders, which are often characterized by variations in the astrocyte protein markers gfap and s100b, in addition to alterations in some of its metabolic functions. |
2024-03-27 |
2024-03-29 |
Not clear |
| Jéssica Taday, Fernanda Telles Fróes, Marina Seady, Carlos Alberto Gonçalves, Marina Concli Leit. In Vitro Astroglial Dysfunction Induced by Neurotoxins: Mimicking Astrocytic Metabolic Alterations of Alzheimer's Disease. Metabolites. vol 14. issue 3. 2024-03-27. PMID:38535311. |
we showed that mg, lps, stz and fc similarly caused astrocyte dysfunction by increasing gfap and reducing s100b secretion. |
2024-03-27 |
2024-03-29 |
Not clear |
| Nicholas Guerini Selistre, Leticia Rodrigues, Barbara Carolina Federhen, Vitor Gayger-Dias, Jéssica Taday, Krista Mineia Wartchow, Carlos-Alberto Gonçalve. S100B Secretion in Astrocytes, Unlike C6 Glioma Cells, Is Downregulated by Lactate. Metabolites. vol 14. issue 1. 2024-01-26. PMID:38276297. |
however, in high-glucose medium, c6 s100b secretion increases, in contrast to the trend in primary astrocyte cultures. |
2024-01-26 |
2024-01-28 |
Not clear |
| Nicholas Guerini Selistre, Leticia Rodrigues, Barbara Carolina Federhen, Vitor Gayger-Dias, Jéssica Taday, Krista Mineia Wartchow, Carlos-Alberto Gonçalve. S100B Secretion in Astrocytes, Unlike C6 Glioma Cells, Is Downregulated by Lactate. Metabolites. vol 14. issue 1. 2024-01-26. PMID:38276297. |
herein, we investigate the impact of fc on s100b secretion in primary astrocyte cultures, acute hippocampal slices and c6 glioma cells, as well as lactate mediation. |
2024-01-26 |
2024-01-28 |
Not clear |
| Juan Xia, Longen Yang, Chengyi Huang, Shuyi Deng, Zhiyou Yang, Yongping Zhang, Cai Zhang, Cai Son. Omega-3 Polyunsaturated Fatty Acid Eicosapentaenoic Acid or Docosahexaenoic Acid Improved Ageing-Associated Cognitive Decline by Regulating Glial Polarization. Marine drugs. vol 21. issue 7. 2023-07-28. PMID:37504929. |
astrocyte a1 polarization presented increasing s100b and c3 but decreasing a2 parameter s100a10 in the ageing brain, which were restored by both pufas, while dha was more effective on s100a10 than epa. |
2023-07-28 |
2023-08-14 |
rat |
| Maria Elisabetta Clementi, Beatrice Sampaolese, Gabriele Di Sante, Francesco Ria, Rosa Di Liddo, Vincenzo Romano Spica, Fabrizio Michett. S100B Expression Plays a Crucial Role in Cytotoxicity, Reactive Oxygen Species Generation and Nitric Oxide Synthase Activation Induced by Amyloid β-Protein in an Astrocytoma Cell Line. International journal of molecular sciences. vol 24. issue 6. 2023-03-29. PMID:36982288. |
we used an astrocytoma cell line (u373 mg) silenced for s100b, and stimulated it with amyloid beta-peptide (aβ) as a known paradigm factor for astrocyte activation, and showed that the ability of the cell (including the gene machinery) to express s100b is a prerequisite for inducing reactive astrocytic features, such as ros generation, nos activation and cytotoxicity. |
2023-03-29 |
2023-08-14 |
Not clear |
| Maria Elisabetta Clementi, Beatrice Sampaolese, Gabriele Di Sante, Francesco Ria, Rosa Di Liddo, Vincenzo Romano Spica, Fabrizio Michett. S100B Expression Plays a Crucial Role in Cytotoxicity, Reactive Oxygen Species Generation and Nitric Oxide Synthase Activation Induced by Amyloid β-Protein in an Astrocytoma Cell Line. International journal of molecular sciences. vol 24. issue 6. 2023-03-29. PMID:36982288. |
the conclusive aim of the present study was to show a causative linkage between the cell expression of s100b and induction of astrocyte activation processes, such as cytotoxicity, ros and nos activation. |
2023-03-29 |
2023-08-14 |
Not clear |
| Sara Haratizadeh, Mehdi Ranjbar, Mohsen Basiri, Masoumeh Nozar. Astrocyte responses to postnatal erythropoietin and nano-erythropoietin treatments in a valproic acid-induced animal model of autism. Journal of chemical neuroanatomy. 2023-03-14. PMID:36918074. |
in the present study, we examined the therapeutic effects of postnatal erythropoietin on stereotypic behaviors and astrocyte responses via glial fibrillary acidic protein (gfap) and s100 calcium-binding protein b (s100b) immunohistochemistry in a valproic acid (vpa) animal model of autism. |
2023-03-14 |
2023-08-14 |
Not clear |
| Abhishek Dahal, Karthivashan Govindarajan, Satyabrata Ka. Administration of kainic acid differentially alters astrocyte markers and transiently enhanced phospho-tau level in adult rat hippocampus. Neuroscience. 2023-02-22. PMID:36805001. |
our results reveal that levels/expression of various astrocyte markers such as gfap, vimentin, s100b, aldh1l1, but not gs, are increased in the hippocampus of ka-treated rats. |
2023-02-22 |
2023-08-14 |
human |
| Rafael Teixeira Ribeiro, Andrey Vinícios Soares Carvalho, Rafael Palavro, Luz Elena Durán-Carabali, Ângela Beatris Zemniaçak, Alexandre Umpierrez Amaral, Carlos Alexandre Netto, Moacir Wajne. L-2-Hydroxyglutaric Acid Administration to Neonatal Rats Elicits Marked Neurochemical Alterations and Long-Term Neurobehavioral Disabilities Mediated by Oxidative Stress. Neurotoxicity research. 2022-12-29. PMID:36580261. |
l-2-hg also decreased the content of neun, mbp, and cnpase, and increased s100b, gfap, and iba1 in the cerebral cortex and striatum at postnatal days 15 and 75, implying long-standing neuronal loss, demyelination, astrocyte reactivity, and increased inflammatory response, respectively. |
2022-12-29 |
2023-08-14 |
rat |
| Adriana Fernanda K Vizuete, Miriara B Leal, Ana Paula Moreira, Marina Seady, Jéssica Taday, Carlos-Alberto Gonçalve. Arundic acid (ONO-2506) downregulates neuroinflammation and astrocyte dysfunction after status epilepticus in young rats induced by Li-pilocarpine. Progress in neuro-psychopharmacology & biological psychiatry. 2022-12-24. PMID:36565981. |
glial fibrillary acidic protein (gfap) and s100 calcium-binding protein b (s100b) are astrocyte biomarkers associated with brain injury. |
2022-12-24 |
2023-08-14 |
rat |
| Adriana Fernanda K Vizuete, Miriara B Leal, Ana Paula Moreira, Marina Seady, Jéssica Taday, Carlos-Alberto Gonçalve. Arundic acid (ONO-2506) downregulates neuroinflammation and astrocyte dysfunction after status epilepticus in young rats induced by Li-pilocarpine. Progress in neuro-psychopharmacology & biological psychiatry. 2022-12-24. PMID:36565981. |
we hypothesize that arundic acid (ono-2506), which is known as an inhibitor of s100b synthesis and secretion, protects the hippocampal tissue from neuroinflammation and astrocyte dysfunction after status epileptics (se) induction by li-pilocarpine in young rats. |
2022-12-24 |
2023-08-14 |
rat |
| Johanna Wallensten, Fariborz Mobarrez, Marie Åsberg, Kristian Borg, Aniella Beser, Alexander Wilczek, Anna Nage. Plasma levels of S100B and neurofilament light chain protein in stress-related mental disorders. Scientific reports. vol 12. issue 1. 2022-05-18. PMID:35585111. |
we also investigated whether levels of s100b and nf-l correlated with levels of astrocyte-derived extracellular vesicles (evs that indicate astrocyte activation or apoptosis) and with symptom severity. |
2022-05-18 |
2023-08-13 |
Not clear |
| Ali Mamivand, Shiva Bayat, Abolfazl Maghrouni, Sasan Shabani, Alireza Khoshnevisan, Hiva Saffar, Mina Tabriz. Data mining of bulk and single-cell RNA sequencing introduces OBI1-AS1 as an astrocyte marker with possible role in glioma recurrence and progression. Clinical epigenetics. vol 14. issue 1. 2022-03-09. PMID:35260196. |
our study indicated that lncrnas, like obi1-as1, could be extremely precise in identifying the astrocyte cluster in the single-cell transcriptome and demonstrating superiority to well-established astrocyte markers such as gfap, s100b, aldh1l1, and aqp4. |
2022-03-09 |
2023-08-13 |
Not clear |
| Junqing Du, Min Yi, Fang Zhou, Wanjun He, Aifen Yang, Mengsheng Qiu, Hao Huan. S100B is selectively expressed by gray matter protoplasmic astrocytes and myelinating oligodendrocytes in the developing CNS. Molecular brain. vol 14. issue 1. 2021-11-18. PMID:34615523. |
based on these molecular and genetic studies, we conclude that s100b is not a specific marker for astrocyte lineage; instead, it marks protoplasmic astrocytes in the gray matter and differentiating oligodendrocytes. |
2021-11-18 |
2023-08-13 |
Not clear |
| W Sue T Griffin, Steven W Barge. Neuroinflammatory Cytokines-The Common Thread in Alzheimer's Pathogenesis. US neurology. vol 6. issue 2. 2021-10-21. PMID:22408651. |
this finding can be added to the demonstration of il-1 induction of amyloid β (aβ) precursor protein and astrocyte activation with excess production of neuritogenic factor s100b. |
2021-10-21 |
2023-08-12 |
Not clear |
| Ayan Mondal, Punnag Saha, Dipro Bose, Somdatta Chatterjee, Ratanesh K Seth, Shuo Xiao, Dwayne E Porter, Bryan W Brooks, Geoff I Scott, Mitzi Nagarkatti, Prakash Nagarkatti, Saurabh Chatterje. Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent. Toxicology. vol 461. 2021-10-13. PMID:34416350. |
an increased circulatory s100b release, a hallmark of astrocyte activation in mc-lr exposed nafld mice also confirmed bbb integrity loss, but the astrocyte activation observed in vivo was nlrp3 independent suggesting an important role of a secondary s100b mediated crosstalk. |
2021-10-13 |
2023-08-13 |
mouse |
| Odia Osemwegie, Landon Butler, Seenivasan Subbiah, Ernest Smit. Effects of in vitro exposure of perfluorooctanoic acid and monocrotophos on astroglia SVG p12 cells. Journal of applied toxicology : JAT. vol 41. issue 9. 2021-08-16. PMID:33569802. |
the endpoints evaluated include cell viability, intracellular glutamate levels as a marker of astrocyte homeostasis function, differential gene expression for selected proteins, which include inflammatory markers (tachykinin), astrocytosis (nestin), s100b, and metabolism enzymes (cyp1a1). |
2021-08-16 |
2023-08-13 |
Not clear |
| Liam Anuj O'Leary, Naguib Mechawa. Implication of cerebral astrocytes in major depression: A review of fine neuroanatomical evidence in humans. Glia. vol 69. issue 9. 2021-07-09. PMID:33734498. |
this review suggests how reduced astrocyte densities may relate to the association of depressive episodes in mdd with elevated s100 beta (s100b) cerebrospinal fluid serum levels. |
2021-07-09 |
2023-08-13 |
human |