| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kai He, Xiaoying Wang, Tingting Li, Yanfei Li, Linlin M. Chlorogenic Acid Attenuates Isoproterenol Hydrochloride-Induced Cardiac Hypertrophy in AC16 Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway. Molecules (Basel, Switzerland). vol 29. issue 4. 2024-02-24. PMID:38398512. |
chlorogenic acid attenuates isoproterenol hydrochloride-induced cardiac hypertrophy in ac16 cells by inhibiting the wnt/β-catenin signaling pathway. |
2024-02-24 |
2024-02-26 |
Not clear |
| Zhuo-Jing Yang, Chun-Ling Guo, Yu-Xin Gong, Long Li, Li-Li Wang, Hui-Min Liu, Ji-Min Cao, Zhao-Yang L. Dapagliflozin Suppresses Isoprenaline-Induced Cardiac Hypertrophy via Inhibition of Mitochondrial Fission. Journal of cardiovascular pharmacology. 2024-02-06. PMID:38030139. |
by continuously infusing isoprenaline (iso) for two weeks using a subcutaneous osmotic pump, a cardiac hypertrophic model was established in male c57bl/6 mice. |
2024-02-06 |
2024-02-09 |
mouse |
| Jacob J Russell, Srinivas Mummidi, Vincent G Demarco, Laurel A Grisanti, Chastidy A Bailey, Shawn B Bender, Bysani Chandraseka. Integrated miRNA-mRNA networks underlie attenuation of chronic β-adrenergic stimulation-induced cardiac remodeling by minocycline. Physiological genomics. 2024-02-05. PMID:38314697. |
isoproterenol infusion induced cardiac hypertrophy, with no change in cardiac function, that was prevented by minocycline. |
2024-02-05 |
2024-02-09 |
mouse |
| Zeyu Li, Ou Hu, Suowen Xu, Chenjia Lin, Wenjing Yu, Dinghu Ma, Jing Lu, Peiqing Li. The SIRT3-ATAD3A axis regulates MAM dynamics and mitochondrial calcium homeostasis in cardiac hypertrophy. International journal of biological sciences. vol 20. issue 3. 2024-01-22. PMID:38250153. |
atad3a prevents isoproterenol (iso)-induced mitochondrial calcium accumulation, improving mitochondrial dysfunction and er stress, which preserves cardiac function and attenuates cardiac hypertrophy. |
2024-01-22 |
2024-01-24 |
Not clear |
| Jiachen Xu, Shiqi Liang, Qinyan Wang, Qingsong Zheng, Mengyang Wang, Jinfu Qian, Tianxiang Yu, Shuaijie Lou, Wu Luo, Hao Zhou, Guang Lian. JOSD2 mediates isoprenaline-induced heart failure by deubiquitinating CaMKIIδ in cardiomyocytes. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-01-10. PMID:38195959. |
in this study, we demonstrated that deficiency of a deubiquitinase, josephin domain-containing protein 2 (josd2), ameliorated isoprenaline (iso)- and myocardial infarction (mi)-induced cardiac hypertrophy, fibrosis, and dysfunction both in vitro and in vivo. |
2024-01-10 |
2024-01-13 |
Not clear |
| Li Xianchao, Yang Wu, Yunzhao Yang, Yaohua Wu, Xi Yu, Wenjuan H. Omaveloxolone ameliorates isoproterenol-induced pathological cardiac hypertrophy in mice. Free radical research. 2023-12-25. PMID:38145457. |
in this study, an isoproterenol (iso)-induced pathological cardiac hypertrophy model was established to investigate the protective effect of omaveloxolone in vivo and in vitro. |
2023-12-25 |
2023-12-27 |
mouse |
| Chan-Ok Son, Mi-Hyeon Hong, Hye-Yoom Kim, Byung-Hyuk Han, Chang-Seob Seo, Ho-Sub Lee, Jung-Joo Yoon, Dae-Gill Kan. Sibjotang Protects against Cardiac Hypertrophy In Vitro and In Vivo. Life (Basel, Switzerland). vol 13. issue 12. 2023-12-23. PMID:38137908. |
in vitro, h9c2 cells were induced by dox (1 μm) in the presence or absence of sjt (1-5 μg/ml) and incubated for 24 h. in vivo, sjt was administrated to isoproterenol (iso)-induced cardiac hypertrophy mice ( |
2023-12-23 |
2023-12-25 |
mouse |
| Yu Sun, Jin Dong, Xiaohong Chai, Jingping Wang, Bao Li, Jinjing Yan. Semaphorin‑3A alleviates cardiac hypertrophy by regulating autophagy. Experimental and therapeutic medicine. vol 27. issue 1. 2023-12-21. PMID:38125367. |
the present study evaluated the role of semaphorin-3a (sema3a), a neurochemical inhibitor, in cardiac hypertrophy, utilizing an isoproterenol (iso) induced h9c2 cell model. |
2023-12-21 |
2023-12-23 |
Not clear |
| Huiling Luan, Zhenhui Wang, Zhenzhen Zhang, Baohua Hou, Zhenzhen Liu, Lanping Yang, Mengmeng Yang, Yile Ma, Baobao Zhan. Brassica oleracea L. extract ameliorates isoproterenol- induced myocardial injury by regulating HIF-1α-mediated glycolysis. Fitoterapia. 2023-10-31. PMID:37907131. |
the effects of boe on myocardial cells were evaluated using isoproterenol (iso)-treated h9c2 cells and wistar rats, and the results revealed that boe could inhibit cardiomyocyte hypertrophy and reduce the levels of b-type natriuretic peptide, nitric oxide, reactive oxygen species, lactic acid, and pyruvic acid. |
2023-10-31 |
2023-11-08 |
rat |
| Wenqi Li, Yuzhong Zhu, Wenjing Wang, Dan He, Lei Feng, Zijian L. Src tyrosine kinase promotes cardiac remodeling induced by chronic sympathetic activation. Bioscience reports. 2023-08-31. PMID:37650260. |
our findings demonstrated that src mediates isoproterenol (iso)-induced cardiac hypertrophy, fibrosis, and inflammation in vivo. |
2023-08-31 |
2023-09-07 |
Not clear |
| Samantha Morón-Ros, Albert Blasco-Roset, Artur Navarro-Gascon, Celia Rupérez, Monica Zamora, Fatima Crispi, Iker Uriarte, Maite G Fernández-Barrena, Matias Avila, Gemma Ferrer-Curriu, Josep Lupón, Antoni Bayés-Genis, Francesc Villarroya, Aleix Gavaldà-Navarro, Anna Planavil. A new FGF15/19-mediated gut-to-heart axis controls cardiac hypertrophy. The Journal of pathology. 2023-08-31. PMID:37650293. |
we found that mice lacking fgf15 did not develop cardiac hypertrophy in response to three different pathophysiological stimuli (high-fat diet, isoproterenol, or cold exposure). |
2023-08-31 |
2023-09-07 |
mouse |
| Meifang Chen, Liming Peng, Chenglong Zhang, Qiong Liu, Tianyi Long, Qiying Xi. Gut microbiota might mediate the benefits of high-fiber/acetate diet to cardiac hypertrophy mice. Journal of physiology and biochemistry. 2023-08-03. PMID:37537429. |
the mice model of isoproterenol (iso)-induced cardiac hypertrophy was constructed and verified for physiological, functional, and fibrotic alterations in this study. |
2023-08-03 |
2023-08-14 |
mouse |
| Dingyan Zhou, Weizhe Liu, Juanjuan Zhang, Yucui Dong, Jiangli Wu, Yu Zhang, Cheng Dai, Tingting Zhang, Gaoshan Yang, Yue Zhang, Aiying L. Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4. Cell death discovery. vol 9. issue 1. 2023-08-01. PMID:37528096. |
in this study, the mouse model of cardiac hypertrophy was established by isoprenaline (iso) induction with or without bel treatment. |
2023-08-01 |
2023-08-14 |
mouse |
| Zhao Fang, Shuang Li, Feierkaiti Yushanjiang, Gaoke Feng, Shengyu Cui, Shan Hu, Xuejun Jiang, Chengyin Li. Curcumol alleviates cardiac remodeling via the AKT/NF-κB pathway. International immunopharmacology. vol 122. 2023-07-01. PMID:37392572. |
curcumol significantly attenuated cardiac dysfunction, myocardial fibrosis, and hypertrophy in the animal model of isoproterenol (iso)-induced cardiac remodeling. |
2023-07-01 |
2023-08-14 |
mouse |
| Peilei Lu, Danyu Zhang, Fan Ding, Jialu Ma, Yang K Xiang, Meimi Zha. Silencing of circCacna1c Inhibits ISO-Induced Cardiac Hypertrophy through miR-29b-2-5p/NFATc1 Axis. Cells. vol 12. issue 12. 2023-06-28. PMID:37371137. |
adult male c57bl/6 mice and h9c2 cells were treated with isoprenaline hydrochloride (iso) to establish a hypertrophy model. |
2023-06-28 |
2023-08-14 |
mouse |
| Andrea Ruiz-Velasco, Rida Raja, Xinyi Chen, Haresh Ganenthiran, Namrita Kaur, Nasser Hawimel O Alatawi, Jessica M Miller, Riham R E Abouleisa, Qinghui Ou, Xiangjun Zhao, Oveena Fonseka, Xin Wang, Susanne S Hille, Norbert Frey, Tao Wang, Tamer M A Mohamed, Oliver J Müller, Elizabeth J Cartwright, Wei Li. Restored autophagy is protective against PAK3-induced cardiac dysfunction. iScience. vol 26. issue 6. 2023-06-16. PMID:37324527. |
myocardium with pak3 overexpression displayed hypertrophic growth, excessive fibrosis, and aggravated apoptosis following isoprenaline stimulation as early as two days. |
2023-06-16 |
2023-08-14 |
mouse |
| Lintong Men, Junyi Guo, Yu Cao, Bingyu Huang, Qian Wang, Shengqi Huo, Moran Wang, Dewei Peng, Lulu Peng, Wei Shi, Sheng Li, Li Lin, Jiagao L. IL-6/gp130/STAT3 signaling contributed to the activation of the PERK arm of the unfolded protein response in response to chronic β-adrenergic stimulation. Free radical biology & medicine. 2023-06-12. PMID:37307935. |
bazedoxifene (5mg/kg/day by oral gavage once a day) exhibited similar effect as carvedilol (10mg/kg/day by oral gavage once a day) on attenuating chronic isoproterenol (30mg/kg by abdominal injection once a day, 7 days) induced cardiac systolic dysfunction, cardiac hypertrophy and fibrosis in c57bl/6 mice. |
2023-06-12 |
2023-08-14 |
mouse |
| Zhen Guo, Yue-Huai Hu, Guo-Shuai Feng, Carla Valenzuela Ripoll, Zhen-Zhen Li, Si-Dong Cai, Qian-Qian Wang, Wen-Wei Luo, Qian Li, Li-Ying Liang, Zhong-Kai Wu, Ji-Guo Zhang, Ali Javaheri, Lei Wang, Jing Lu, Pei-Qing Li. JMJD6 protects against isoproterenol-induced cardiac hypertrophy via inhibition of NF-κB activation by demethylating R149 of the p65 subunit. Acta pharmacologica Sinica. 2023-05-15. PMID:37186122. |
cardiac hypertrophy was induced in rats by subcutaneous injection of isoproterenol (iso, 1.2 mg·kg |
2023-05-15 |
2023-08-14 |
rat |
| Zhuang Ma, Zuheng Liu, Xudong Li, Hao Zhang, Dunzheng Han, Wenjun Xiong, Haobin Zhou, Xi Yang, Qingchun Zeng, Hao Ren, Dingli X. Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function. Biology. vol 12. issue 4. 2023-04-28. PMID:37106782. |
we studied the function of pink1 in mitophagy in isoproterenol (iso)-induced cardiomyocyte injury and transverse aortic constriction (tac)-induced myocardial hypertrophy. |
2023-04-28 |
2023-08-14 |
mouse |
| HuiTing Liu, ZhiXiang Zhou, HuaNian Deng, Zhen Tian, ZeFan Wu, XiYan Liu, Zhong Ren, ZhiSheng Jian. Trim65 attenuates isoproterenol-induced cardiac hypertrophy by promoting autophagy and ameliorating mitochondrial dysfunction via the Jak1/Stat1 signaling pathway. European journal of pharmacology. 2023-04-20. PMID:37080331. |
in this study, the effects of trim65 on isoproterenol (iso)-induced cardiac hypertrophy and the underlying mechanisms were investigated. |
2023-04-20 |
2023-08-14 |
mouse |