| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matteo Urru, Daniela Buonvicino, Alessandra Pistolesi, Sara Paccosi, Alberto Chiarug. Histone Deacetylase Inhibitors Counteract CGRP Signaling and Pronociceptive Sensitization in a Rat Model of Medication Overuse Headache. The journal of pain. 2022-06-14. PMID:35700873. |
within the trigeminal nucleus caudalis (tnc), transcripts for these genes were neither upregulated by eletriptan nor altered by concomitant treatment with panobinostat or givinostat. |
2022-06-14 |
2023-08-14 |
rat |
| Alejandro Labastida-Ramírez, Eloísa Rubio-Beltrán, Kristian A Haanes, Kayi Y Chan, Ingrid M Garrelds, Kirk W Johnson, Alexander H J Danser, Carlos M Villalón, Antoinette MaassenVanDenBrin. Lasmiditan inhibits calcitonin gene-related peptide release in the rodent trigeminovascular system. Pain. vol 161. issue 5. 2021-04-22. PMID:31977930. |
for this purpose, we have comparatively analysed the inhibition of several components of the trigeminovascular system induced by lasmiditan and sumatriptan through: ex vivo kcl-induced cgrp release from isolated dura mater, trigeminal ganglion, and trigeminal nucleus caudalis of mice; and in vivo dural vasodilation in the rat closed-cranial window model induced by endogenous (electrical stimulation and capsaicin) and exogenous cgrp. |
2021-04-22 |
2023-08-13 |
mouse |
| Eleonóra Spekker, Klaudia Flóra Laborc, Zsuzsanna Bohár, Gábor Nagy-Grócz, Annamária Fejes-Szabó, Mónika Szűcs, László Vécsei, Árpád Párdut. Effect of dural inflammatory soup application on activation and sensitization markers in the caudal trigeminal nucleus of the rat and the modulatory effects of sumatriptan and kynurenic acid. The journal of headache and pain. vol 22. issue 1. 2021-04-02. PMID:33789568. |
effect of dural inflammatory soup application on activation and sensitization markers in the caudal trigeminal nucleus of the rat and the modulatory effects of sumatriptan and kynurenic acid. |
2021-04-02 |
2023-08-13 |
rat |
| Kayi Y Chan, Alejandro Labastida-Ramírez, Martha B Ramírez-Rosas, Sieneke Labruijere, Ingrid M Garrelds, Alexander Hj Danser, Arn Mjm van den Maagdenberg, Antoinette MaassenVanDenBrin. Trigeminovascular calcitonin gene-related peptide function in Cacna1a R192Q-mutated knock-in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 39. issue 4. 2020-03-02. PMID:28792272. |
the ex vivo release of cgrp was not different in the components of the trigeminovascular system between genotypes; however, sumatriptan diminished the release in the trigeminal ganglion, trigeminal nucleus caudalis and dura mater but only in wild-type mice. |
2020-03-02 |
2023-08-13 |
mouse |
| Geoffrey A Lamber. Preclinical neuropharmacology of naratriptan. CNS drug reviews. vol 11. issue 3. 2006-02-08. PMID:16389295. |
in the periaqueductal gray matter and in the nucleus raphe magnus, naratriptan selectively activates inhibitory neurons which project to the trigeminal nucleus and spinal cord and which exert inhibitory influences on trigeminovascular sensory input. |
2006-02-08 |
2023-08-12 |
Not clear |
| A Pardutz, E Szatmári, L Vecsei, J Schoene. Nitroglycerin-induced nNOS increase in rat trigeminal nucleus caudalis is inhibited by systemic administration of lysine acetylsalicylate but not of sumatriptan. Cephalalgia : an international journal of headache. vol 24. issue 6. 2005-01-25. PMID:15154853. |
nitroglycerin-induced nnos increase in rat trigeminal nucleus caudalis is inhibited by systemic administration of lysine acetylsalicylate but not of sumatriptan. |
2005-01-25 |
2023-08-12 |
rat |
| T Bartsch, Y E Knight, P J Goadsb. Activation of 5-HT(1B/1D) receptor in the periaqueductal gray inhibits nociception. Annals of neurology. vol 56. issue 3. 2004-10-06. PMID:15349864. |
the 5-ht(1b/1d) agonist, naratriptan, was microinjected into the ventrolateral periaqueductal gray (vlpag), and activity in the trigeminal nucleus caudalis (tnc) was monitored. |
2004-10-06 |
2023-08-12 |
Not clear |
| D D Mitsikostas, M Sanchez del Rio, M A Moskowitz, C Waebe. Both 5-HT1B and 5-HT1F receptors modulate c-fos expression within rat trigeminal nucleus caudalis. European journal of pharmacology. vol 369. issue 3. 1999-06-29. PMID:10225363. |
sumatriptan and ly 344864 decreased the number of capsaicin-induced c-fos-like immunoreactive cells within trigeminal nucleus caudalis (id50 = 0.04 and 0.6 mg kg(-1)). |
1999-06-29 |
2023-08-12 |
rat |
| D D Mitsikostas, M Sanchez del Rio, M A Moskowitz, C Waebe. Both 5-HT1B and 5-HT1F receptors modulate c-fos expression within rat trigeminal nucleus caudalis. European journal of pharmacology. vol 369. issue 3. 1999-06-29. PMID:10225363. |
to establish the relative importance of these subtypes, we compared the effects of sumatriptan with those of a selective 5-ht1f receptor agonist (ly 344864) on c-fos protein expression in the trigeminal nucleus caudalis. |
1999-06-29 |
2023-08-12 |
rat |
| K L Hoskin, P J Goadsb. Comparison of more and less lipophilic serotonin (5HT1B/1D) agonists in a model of trigeminovascular nociception in cat. Experimental neurology. vol 150. issue 1. 1998-04-14. PMID:9514827. |
we compared the dorsal horns of the medulla (trigeminal nucleus caudalis) and the c1 and c2 cervical spinal cords in control animals with those receiving zolmitriptan or sumatriptan. |
1998-04-14 |
2023-08-12 |
cat |
| E Knyihár-Csillik, J Tajti, M Samsam, G Sáry, S Slezák, L Vécse. Effect of a serotonin agonist (sumatriptan) on the peptidergic innervation of the rat cerebral dura mater and on the expression of c-fos in the caudal trigeminal nucleus in an experimental migraine model. Journal of neuroscience research. vol 48. issue 5. 1997-07-28. PMID:9185668. |
effect of a serotonin agonist (sumatriptan) on the peptidergic innervation of the rat cerebral dura mater and on the expression of c-fos in the caudal trigeminal nucleus in an experimental migraine model. |
1997-07-28 |
2023-08-12 |
rat |
| E Knyihár-Csillik, J Tajti, M Samsam, G Sáry, S Slezák, L Vécse. Effect of a serotonin agonist (sumatriptan) on the peptidergic innervation of the rat cerebral dura mater and on the expression of c-fos in the caudal trigeminal nucleus in an experimental migraine model. Journal of neuroscience research. vol 48. issue 5. 1997-07-28. PMID:9185668. |
in the caudal trigeminal nucleus electrical stimulation of the trigeminal ganglion induces, in interneurons, increased expression of the oncoprotein c-fos which is not prevented by intravenous application of sumatriptan. |
1997-07-28 |
2023-08-12 |
rat |
| A Mills, G R Marti. Autoradiographic mapping of [3H]sumatriptan binding in cat brain stem and spinal cord. European journal of pharmacology. vol 280. issue 2. 1995-12-07. PMID:7589183. |
localization studies using 20-25 nm [3h]sumatriptan showed specific binding to cells in the trigeminal nucleus caudalis and nucleus tractus solitarius of the brain stem and the dorsal horn of the spinal cord. |
1995-12-07 |
2023-08-12 |
cat |
| S L Shepheard, D J Williamson, J Williams, R G Hill, R J Hargreave. Comparison of the effects of sumatriptan and the NK1 antagonist CP-99,994 on plasma extravasation in Dura mater and c-fos mRNA expression in trigeminal nucleus caudalis of rats. Neuropharmacology. vol 34. issue 3. 1995-09-01. PMID:7630480. |
comparison of the effects of sumatriptan and the nk1 antagonist cp-99,994 on plasma extravasation in dura mater and c-fos mrna expression in trigeminal nucleus caudalis of rats. |
1995-09-01 |
2023-08-12 |
rat |
| F M Cutrer, D Schoenfeld, V Limmroth, N Panahian, M A Moskowit. Suppression by the sumatriptan analogue, CP-122,288 of c-fos immunoreactivity in trigeminal nucleus caudalis induced by intracisternal capsaicin. British journal of pharmacology. vol 114. issue 5. 1995-07-14. PMID:7780655. |
suppression by the sumatriptan analogue, cp-122,288 of c-fos immunoreactivity in trigeminal nucleus caudalis induced by intracisternal capsaicin. |
1995-07-14 |
2023-08-12 |
Not clear |
| F M Cutrer, D Schoenfeld, V Limmroth, N Panahian, M A Moskowit. Suppression by the sumatriptan analogue, CP-122,288 of c-fos immunoreactivity in trigeminal nucleus caudalis induced by intracisternal capsaicin. British journal of pharmacology. vol 114. issue 5. 1995-07-14. PMID:7780655. |
the effects of an intravenously administered sumatriptan analogue were examined on c-fos-like immunoreactivity (c-fos-li), a marker of neuronal activation, evoked within trigeminal nucleus caudalis (tnc) and other brain stem regions 2 h after intracisternal injection of the irritant, capsaicin (0.1 ml, 0.1 mm), in pentobarbitone-anaesthetized hartley guinea-pigs. |
1995-07-14 |
2023-08-12 |
Not clear |
| K Nozaki, M A Moskowitz, P Boccalin. CP-93,129, sumatriptan, dihydroergotamine block c-fos expression within rat trigeminal nucleus caudalis caused by chemical stimulation of the meninges. British journal of pharmacology. vol 106. issue 2. 1992-11-13. PMID:1327382. |
cp-93,129, sumatriptan, dihydroergotamine block c-fos expression within rat trigeminal nucleus caudalis caused by chemical stimulation of the meninges. |
1992-11-13 |
2023-08-11 |
rat |