| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ravi J Louis, Michelle Lee, Sheng-Han Kuo, Jean-Paul G Vonsattel, Elan D Louis, Phyllis L Faus. Cellular density in the cerebellar molecular layer in essential tremor, spinocerebellar ataxia, and controls. Parkinsonism & related disorders. vol 20. issue 11. 2015-09-04. PMID:25218844. |
in hereditary cerebellar ataxia, purkinje cell loss has been reported to result in a secondary increase in the density of the remaining cell populations in the cerebellar molecular layer. |
2015-09-04 |
2023-08-13 |
Not clear |
| Jan Cendeli. From mice to men: lessons from mutant ataxic mice. Cerebellum & ataxias. vol 1. 2015-09-02. PMID:26331028. |
lurcher, hot-foot, purkinje cell degeneration, nervous, staggerer, weaver, reeler, and scrambler mouse models and mouse models of sca1, sca2, sca3, sca6, sca7, sca23, drpla, niemann-pick disease and friedreich ataxia are reviewed with special regard to cerebellar pathology, pathogenesis, functional changes and possible therapeutic influences, if any. |
2015-09-02 |
2023-08-13 |
mouse |
| Ray X Lee, Jian-Jia Huang, Chiming Huang, Meng-Li Tsai, Chen-Tung Ye. Plasticity of cerebellar Purkinje cells in behavioral training of body balance control. Frontiers in systems neuroscience. vol 9. 2015-08-24. PMID:26300746. |
in this study, we investigated purkinje cell (pc) spike trains as cerebellar cortical output when rats learned to balance on a suspended dowel. |
2015-08-24 |
2023-08-13 |
rat |
| Rodrigo Pascual, Martina Valencia, Sebastián Larrea, Carlos Bustamant. Single course of antenatal betamethasone produces delayed changes in morphology and calbindin-D28k expression in a rat's cerebellar Purkinje cells. Acta neurobiologiae experimentalis. vol 74. issue 4. 2015-08-19. PMID:25576972. |
in the current study, we analyzed the impact of antenatal betamethasone on macroscopic cerebellar development, purkinje cell morphology and the expression of the neuroprotective protein calbindin-d28k. |
2015-08-19 |
2023-08-13 |
rat |
| Rodrigo Pascual, Martina Valencia, Sebastián Larrea, Carlos Bustamant. Single course of antenatal betamethasone produces delayed changes in morphology and calbindin-D28k expression in a rat's cerebellar Purkinje cells. Acta neurobiologiae experimentalis. vol 74. issue 4. 2015-08-19. PMID:25576972. |
animals that were prenatally treated with a single course of betamethasone exhibited long-lasting behavioral changes consistent with anxiety-like behavior in the open-field test, together with (1) reduced cerebellar weight and volume, (2) purkinje cell dendritic atrophy, and (3) an overexpression of calbindin-d28k. |
2015-08-19 |
2023-08-13 |
rat |
| Hunter E Halverson, Andrei Khilkevich, Michael D Mau. Relating cerebellar purkinje cell activity to the timing and amplitude of conditioned eyelid responses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 20. 2015-08-03. PMID:25995469. |
how purkinje cell (pc) activity may be altered by learning is central to theories of the cerebellum. |
2015-08-03 |
2023-08-13 |
Not clear |
| Jui-Yi Hsieh, Brittany Ulrich, Fadi A Issa, Jijun Wan, Diane M Papazia. Rapid development of Purkinje cell excitability, functional cerebellar circuit, and afferent sensory input to cerebellum in zebrafish. Frontiers in neural circuits. vol 8. 2015-07-30. PMID:25565973. |
rapid development of purkinje cell excitability, functional cerebellar circuit, and afferent sensory input to cerebellum in zebrafish. |
2015-07-30 |
2023-08-13 |
zebrafish |
| Elena Parmigiani, Ketty Leto, Chiara Rolando, María Figueres-Oñate, Laura López-Mascaraque, Annalisa Buffo, Ferdinando Ross. Heterogeneity and Bipotency of Astroglial-Like Cerebellar Progenitors along the Interneuron and Glial Lineages. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 19. 2015-07-27. PMID:25972168. |
indeed, the postnatal cerebellum hosts another germinal site along the purkinje cell layer (pcl), in which bergmann glia are generated up to first the postnatal weeks, which was proposed to be neurogenic. |
2015-07-27 |
2023-08-13 |
mouse |
| Boeke J van Beugen, Xin Qiao, Dana H Simmons, Chris I De Zeeuw, Christian Hanse. Enhanced AMPA receptor function promotes cerebellar long-term depression rather than potentiation. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 12. 2015-07-16. PMID:25403454. |
here, we show that the ampakine cx546 raises the amplitude and slows the decay time of excitatory postsynaptic currents (epscs) at cerebellar parallel fiber (pf) to purkinje cell synapses, thus resembling cx546 effects described at hippocampal synapses. |
2015-07-16 |
2023-08-13 |
Not clear |
| Julie Renaud, Alain Chédota. Time-lapse analysis of tangential migration in Sema6A and PlexinA2 knockouts. Molecular and cellular neurosciences. vol 63. 2015-07-09. PMID:25284064. |
in the developing cerebellum, granule cells migrate tangentially in the external granule cell layer and then radially and inward, across the molecular layer and purkinje cell layer. |
2015-07-09 |
2023-08-13 |
mouse |
| Tomoko Ishibashi, Akiko Kodama, Hiroko Bab. Disruption of paranodal axo-glial interaction and/or absence of sulfatide causes irregular type I inositol 1,4,5-trisphosphate receptor deposition in cerebellar Purkinje neuron axons. Journal of neuroscience research. vol 93. issue 1. 2015-07-08. PMID:25093737. |
although we did not observed significant defects in the nodal regions in several areas of the cns, myelinated internodal regions showed many focal swellings in purkinje cell axons in the cerebellum, and the number and the size of swellings increased with age. |
2015-07-08 |
2023-08-13 |
mouse |
| Katherine E Hekman, Christopher M Gome. The autosomal dominant spinocerebellar ataxias: emerging mechanistic themes suggest pervasive Purkinje cell vulnerability. Journal of neurology, neurosurgery, and psychiatry. vol 86. issue 5. 2015-06-22. PMID:25136055. |
the spinocerebellar ataxias are a genetically heterogeneous group of disorders with clinically overlapping phenotypes arising from purkinje cell degeneration, cerebellar atrophy and varying degrees of degeneration of other grey matter regions. |
2015-06-22 |
2023-08-13 |
Not clear |
| Filippo Tempia, Eriola Hoxha, Giulia Negro, Musaad A Alshammari, Tahani K Alshammari, Neli Panova-Elektronova, Fernanda Laezz. Parallel fiber to Purkinje cell synaptic impairment in a mouse model of spinocerebellar ataxia type 27. Frontiers in cellular neuroscience. vol 9. 2015-06-19. PMID:26089778. |
to gain insights in the cerebellar deficits in the animal model of the human disease, we applied whole-cell voltage-clamp in the acute cerebellar slice preparation to examine the properties of parallel fibers (pf) to purkinje neuron synapses in fgf14 (-/-) mice and wild type littermates. |
2015-06-19 |
2023-08-13 |
mouse |
| Pascal Grange, Idan Menashe, Michael Hawrylyc. Cell-type-specific neuroanatomy of cliques of autism-related genes in the mouse brain. Frontiers in computational neuroscience. vol 9. 2015-06-15. PMID:26074809. |
these pairs predominantly consist of one cortical pyramidal cell and one cerebellar cell (which can be either a granule cell or a purkinje cell). |
2015-06-15 |
2023-08-13 |
mouse |
| Lu Yu, Toshiharu Iwasaki, Ming Xu, Ronny Lesmana, Yu Xiong, Noriaki Shimokawa, William W Chin, Noriyuki Koibuch. Aberrant cerebellar development of transgenic mice expressing dominant-negative thyroid hormone receptor in cerebellar Purkinje cells. Endocrinology. vol 156. issue 4. 2015-06-11. PMID:25603044. |
in the primary cerebellar culture, th-induced purkinje cell dendrite arborization was also suppressed. |
2015-06-11 |
2023-08-13 |
mouse |
| Shinya Kawata, Taisuke Miyazaki, Maya Yamazaki, Takayasu Mikuni, Miwako Yamasaki, Kouichi Hashimoto, Masahiko Watanabe, Kenji Sakimura, Masanobu Kan. Global scaling down of excitatory postsynaptic responses in cerebellar Purkinje cells impairs developmental synapse elimination. Cell reports. vol 8. issue 4. 2015-05-26. PMID:25127140. |
we examined how relative differences in synaptic strengths among competing inputs and/or absolute synaptic strengths contribute to climbing fiber (cf) to purkinje cell (pc) synapse elimination in the cerebellum. |
2015-05-26 |
2023-08-13 |
mouse |
| A Bertalan, E N Glass, M Kent, A De LaHunta, C Bradle. Late-onset cerebellar abiotrophy in a Labrador Retriever. Australian veterinary journal. vol 92. issue 9. 2015-05-12. PMID:24995529. |
postmortem histopathological evaluation of the brain showed diffuse degeneration of purkinje cell neurones with secondary granule cell loss in the cerebellum, in addition to pigment inclusions in brainstem neurones. |
2015-05-12 |
2023-08-13 |
Not clear |
| Janelle M P Pakan, David J Graham, Douglas R Wyli. Climbing fiber projections in relation to zebrin stripes in the ventral uvula in pigeons. The Journal of comparative neurology. vol 522. issue 16. 2015-05-11. PMID:24825798. |
the cerebellum consists of sagittally oriented zones that are delineated by afferent input, purkinje cell response properties, and the expression of molecular markers such as zebrin ii (zii). |
2015-05-11 |
2023-08-13 |
pigeon |
| Jingmin Ji, Melanie L Hassler, Etsuko Shimobayashi, Nagendher Paka, Raphael Streit, Josef P Kapfhamme. Increased protein kinase C gamma activity induces Purkinje cell pathology in a mouse model of spinocerebellar ataxia 14. Neurobiology of disease. vol 70. 2015-04-21. PMID:24937631. |
spinocerebellar ataxias (scas) are hereditary diseases leading to purkinje cell degeneration and cerebellar dysfunction. |
2015-04-21 |
2023-08-13 |
mouse |
| Toshihiro Kitama, Junya Komagata, Kenichi Ozawa, Yutaka Suzuki, Yu Sat. Plane-specific Purkinje cell responses to vertical head rotations in the cat cerebellar nodulus and uvula. Journal of neurophysiology. vol 112. issue 3. 2015-04-09. PMID:24805078. |
plane-specific purkinje cell responses to vertical head rotations in the cat cerebellar nodulus and uvula. |
2015-04-09 |
2023-08-13 |
cat |