| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Toshihiro Kitama, Junya Komagata, Kenichi Ozawa, Yutaka Suzuki, Yu Sat. Plane-specific Purkinje cell responses to vertical head rotations in the cat cerebellar nodulus and uvula. Journal of neurophysiology. vol 112. issue 3. 2015-04-09. PMID:24805078. |
we recorded simple spike (ss) and complex spike (cs) firing of purkinje cell in the cerebellar nodulus and uvula of awake, head-restrained cats during sinusoidal vertical rotation of the head in four stimulus planes (pitch, roll, and two vertical canal planes). |
2015-04-09 |
2023-08-13 |
cat |
| Eleonora Corradini, Raghavan Vallur, Linsey M Raaijmakers, Susanne Feil, Robert Feil, Albert J R Heck, Arjen Scholte. Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse. Molecular & cellular proteomics : MCP. vol 13. issue 8. 2015-04-08. PMID:24925903. |
in this way, removal of cgki could be linked to impaired cerebellar long-term depression at purkinje cell synapses. |
2015-04-08 |
2023-08-13 |
mouse |
| Marion Najac, Indira M Rama. Integration of Purkinje cell inhibition by cerebellar nucleo-olivary neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 2. 2015-04-07. PMID:25589749. |
integration of purkinje cell inhibition by cerebellar nucleo-olivary neurons. |
2015-04-07 |
2023-08-13 |
mouse |
| John M Starbuck, Tara Dutka, Tabetha S Ratliff, Roger H Reeves, Joan T Richtsmeie. Overlapping trisomies for human chromosome 21 orthologs produce similar effects on skull and brain morphology of Dp(16)1Yey and Ts65Dn mice. American journal of medical genetics. Part A. vol 164A. issue 8. 2015-03-31. PMID:24788405. |
cerebellar cross-sectional area, purkinje cell linear density, and granule cell density were evaluated relative to euploid littermates. |
2015-03-31 |
2023-08-13 |
mouse |
| Liliana S Mendonça, Clévio Nóbrega, Hirokazu Hirai, Brian K Kaspar, Luís Pereira de Almeid. Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice. Brain : a journal of neurology. vol 138. issue Pt 2. 2015-03-23. PMID:25527827. |
importantly, cerebellar neural stem cell transplantation mediated a significant and robust alleviation of the motor behaviour impairments, which correlated with preservation from machado-joseph disease-associated neuropathology, namely reduction of purkinje cell loss, reduction of cellular layer shrinkage and mutant atxn3 aggregates. |
2015-03-23 |
2023-08-13 |
mouse |
| Marijn N van Dongen, Freek E Hoebeek, S K E Koekkoek, Chris I De Zeeuw, Wouter A Serdij. High frequency switched-mode stimulation can evoke post synaptic responses in cerebellar principal neurons. Frontiers in neuroengineering. vol 8. 2015-03-23. PMID:25798105. |
these findings are subsequently verified using in vitro experiments in which the response of a purkinje cell is measured due to a stimulation signal in the molecular layer of the cerebellum of a mouse. |
2015-03-23 |
2023-08-13 |
mouse |
| Stefano Masoli, Sergio Solinas, Egidio D'Angel. Action potential processing in a detailed Purkinje cell model reveals a critical role for axonal compartmentalization. Frontiers in cellular neuroscience. vol 9. 2015-03-11. PMID:25759640. |
the purkinje cell (pc) is among the most complex neurons in the brain and plays a critical role for cerebellar functioning. |
2015-03-11 |
2023-08-13 |
Not clear |
| Maren C Kiessling, Andreas Büttner, Camilla Butti, Jens Müller-Starck, Stefan Milz, Patrick R Hof, Hans-Georg Frank, Christoph Schmit. Cerebellar granule cells are generated postnatally in humans. Brain structure & function. vol 219. issue 4. 2015-02-23. PMID:23716277. |
accordingly, approximately 85 % of the cerebellar granule cells are generated postnatally in human, and the number of granule cells per purkinje cell in the human cerebellum increases from 485 at m1 to 2,700 at m10/11, approximately. |
2015-02-23 |
2023-08-12 |
human |
| K Ibhazehiebo, V I Iyawe, Noriyuki Koibuch. Effect of Methamidophos on cerebellar neuronal cells. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 28. issue 2. 2015-02-19. PMID:24937384. |
using primary cerebellar culture from new born rats, we observed that purkinje cell dendrite arborization were greatly impaired in the absence of thyroid hormone (th), however, low dose methamidophos 10-6 m did not significantly impair dendrite arborization of cerebellar purkinje cells in the presence of thyroid hormone (th). |
2015-02-19 |
2023-08-13 |
rat |
| Olatunde Owoeye, Isaac A Adedara, Oluwafemi S Bakare, Oluwatobi A Adeyemo, Christa Egun, Ebenezer O Faromb. Kolaviron and vitamin E ameliorate hematotoxicity and oxidative stress in brains of prepubertal rats treated with an anticonvulsant phenytoin. Toxicology mechanisms and methods. vol 24. issue 5. 2015-02-12. PMID:24712692. |
although pht treatment had no effect on the granular layer, widest diameter of purkinje cells and purkinje layer of the cerebellum, it significantly reduced its molecular layer and the density of purkinje cell. |
2015-02-12 |
2023-08-13 |
rat |
| Elan D Louis, Sheng-Han Kuo, Jean-Paul G Vonsattel, Phyllis L Faus. Torpedo formation and Purkinje cell loss: modeling their relationship in cerebellar disease. Cerebellum (London, England). vol 13. issue 4. 2015-02-09. PMID:24590661. |
torpedo formation and purkinje cell (pc) loss represent standard and inter-related cerebellar responses to injury. |
2015-02-09 |
2023-08-12 |
Not clear |
| Eva K Wirth, B Suman Bharathi, Dolph Hatfield, Marcus Conrad, Markus Brielmeier, Ulrich Schweize. Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons. Biological trace element research. vol 158. issue 2. 2015-02-09. PMID:24599700. |
histological analysis reveals marked cerebellar hypoplasia, associated with purkinje cell death and decreased granule cell proliferation. |
2015-02-09 |
2023-08-12 |
mouse |
| Eva K Wirth, B Suman Bharathi, Dolph Hatfield, Marcus Conrad, Markus Brielmeier, Ulrich Schweize. Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons. Biological trace element research. vol 158. issue 2. 2015-02-09. PMID:24599700. |
neuron-specific inactivation of glutathione peroxidase 4 (gpx4) used the same cre driver phenocopies trna([ser]sec) mutants in several aspects: cerebellar hypoplasia, stripe-like purkinje cell loss, and reduced granule cell proliferation. |
2015-02-09 |
2023-08-12 |
mouse |
| Minerva Martínez-Alfaro, Alfonso Cárabez-Trejo, Francisca Sandoval-Zapata, Verónica Morales-Tlalpan, Lourdes Palma-Tirad. Subsurface cistern (SSC) proliferation in Purkinje cells of the rat cerebellum in response to acute and chronic exposure to paint thinner: A light and electron microscopy study. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 66. issue 7. 2015-01-30. PMID:24820124. |
a histological analysis of the cerebellum of solvent-exposed rats revealed swollen purkinje cell dendrites surrounded by empty space, and electronic microscopy showed an increase in the number of subsurface cisterns (sscs) within their dendritic processes. |
2015-01-30 |
2023-08-13 |
rat |
| Elizabeth K Lucas, Courtney S Reid, Laura J McMeekin, Sarah E Dougherty, Candace L Floyd, Rita M Cowel. Cerebellar transcriptional alterations with Purkinje cell dysfunction and loss in mice lacking PGC-1α. Frontiers in cellular neuroscience. vol 8. 2015-01-22. PMID:25610371. |
cerebellar transcriptional alterations with purkinje cell dysfunction and loss in mice lacking pgc-1α. |
2015-01-22 |
2023-08-13 |
mouse |
| JinBin Tian, Chhavy Tep, Alex Benedick, Nabila Saidi, Jae Cheon Ryu, Mi Lyang Kim, Shankar Sadasivan, John Oberdick, Richard Smeyne, Michael X Zhu, Sung Ok Yoo. p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1. The Journal of biological chemistry. vol 289. issue 45. 2015-01-17. PMID:25253694. |
along with the finding that spine density was reduced in p75(-/-) cerebellum, these data suggest that p75 plays a role in maintaining normalcy of purkinje cell firing in the cerebellum in part by activating rac1 in synaptic compartments and modulating sk channels. |
2015-01-17 |
2023-08-13 |
mouse |
| Farzaneh Najafi, Andrea Giovannucci, Samuel S-H Wang, Javier F Medin. Sensory-driven enhancement of calcium signals in individual Purkinje cell dendrites of awake mice. Cell reports. vol 6. issue 5. 2015-01-06. PMID:24582958. |
climbing fibers (cfs) are thought to contribute to cerebellar plasticity and learning by triggering a large influx of dendritic calcium in the postsynaptic purkinje cell (pc) to signal the occurrence of an unexpected sensory event. |
2015-01-06 |
2023-08-12 |
mouse |
| A G Armién, D L McRuer, M G Ruder, A Wünschman. Purkinje cell heterotopy with cerebellar hypoplasia in two free-living American kestrels (Falco sparverius). Veterinary pathology. vol 50. issue 1. 2014-12-31. PMID:22508700. |
purkinje cell heterotopy with cerebellar hypoplasia in two free-living american kestrels (falco sparverius). |
2014-12-31 |
2023-08-12 |
Not clear |
| A G Armién, D L McRuer, M G Ruder, A Wünschman. Purkinje cell heterotopy with cerebellar hypoplasia in two free-living American kestrels (Falco sparverius). Veterinary pathology. vol 50. issue 1. 2014-12-31. PMID:22508700. |
the authors suggest that this cerebellar abnormality was likely due to a disruption of molecular mechanisms that dictate purkinje cell migration, placement, and maturation in early embryonic development. |
2014-12-31 |
2023-08-12 |
Not clear |
| Karen Bailey, Maryam Rahimi Balaei, Ashraf Mannan, Marc R Del Bigio, Hassan Marzba. Purkinje cell compartmentation in the cerebellum of the lysosomal Acid phosphatase 2 mutant mouse (nax - naked-ataxia mutant mouse). PloS one. vol 9. issue 4. 2014-12-30. PMID:24722417. |
purkinje cell compartmentation in the cerebellum of the lysosomal acid phosphatase 2 mutant mouse (nax - naked-ataxia mutant mouse). |
2014-12-30 |
2023-08-13 |
mouse |