All Relations between cerebellum purkinje cell and cerebellum

Publication Sentence Publish Date Extraction Date Species
Congzhe Hou, Lingcui Ding, Jian Zhang, Yecheng Jin, Chen Sun, Zhenzu Li, Xiaoyang Sun, Tingting Zhang, Aizhen Zhang, Huashun Li, Jiangang Ga. Abnormal cerebellar development and Purkinje cell defects in Lgl1-Pax2 conditional knockout mice. Developmental biology. vol 395. issue 1. 2014-12-10. PMID:25050931. consistent with this abnormal behaviour, homozygous mice possessed a smaller cerebellum with fewer lobes, reduced granule precursor cell (gpc) proliferation, decreased purkinje cell (pc) quantity and dendritic dysplasia. 2014-12-10 2023-08-13 mouse
Naofumi Uesaka, Shinya Kawata, Masanobu Kan. [Cellular and molecular mechanisms of synapse elimination in the Mammalian brain]. Brain and nerve = Shinkei kenkyu no shinpo. vol 66. issue 9. 2014-12-08. PMID:25200578. in the neonatal mouse cerebellum, each purkinje cell is innervated by multiple climbing fibers (cfs). 2014-12-08 2023-08-13 mouse
Guy Cheron, Javier Márquez-Ruiz, Tatsuya Kishino, Bernard Da. Disruption of the LTD dialogue between the cerebellum and the cortex in Angelman syndrome model: a timing hypothesis. Frontiers in systems neuroscience. vol 8. 2014-12-05. PMID:25477791. the control exerted by the cerebellum on the excitation vs. inhibition balance in the cerebral cortex and possible role played by the timing plasticity of the purkinje cell ltd on the spike-timing dependent plasticity (stdp) of the pyramidal neurons are discussed in the context of the present hypothesis. 2014-12-05 2023-08-13 mouse
Denis I Cran. Revisiting the neuropathogenesis of Zellweger syndrome. Neurochemistry international. vol 69. 2014-12-03. PMID:24607700. neuropathological changes include abnormal neuronal migration affecting the cerebral hemispheres, cerebellum and inferior olivary complex, abnormal purkinje cell arborisation, demyelination and post-developmental neuronal degeneration. 2014-12-03 2023-08-12 Not clear
Susan E Maloney, Kevin K Noguchi, David F Wozniak, Stephen C Fowler, Nuri B Farbe. Long-term Effects of Multiple Glucocorticoid Exposures in Neonatal Mice. Behavioral sciences (Basel, Switzerland). vol 1. issue 1. 2014-11-28. PMID:22375274. histopathology studies utilizing stereological neuronal counts conducted in behaviorally-tested mice showed that the dex3 treatment resulted in a significant decrease in the number of neurons in the internal granule layer (igl) of the cerebellum, although the number of neurons in the purkinje cell layer were unchanged. 2014-11-28 2023-08-12 mouse
Jae-Min Lee, Mal-Soon Shin, Eun-Sang Ji, Tae-Woon Kim, Han-Sam Cho, Chang-Ju Kim, Myung-Soo Jang, Tae-Wook Kim, Bo-Kyun Kim, Dong-Hee Ki. Treadmill exercise improves motor coordination through ameliorating Purkinje cell loss in amyloid beta23-35-induced Alzheimer's disease rats. Journal of exercise rehabilitation. vol 10. issue 5. 2014-11-26. PMID:25426461. the present study demonstrated that treadmill exercises alleviated dysfunction of motor coordination and balance by reduction of purkinje cell loss through suppressing reactive astrocytes in the cerebellum of ad rats. 2014-11-26 2023-08-13 rat
Xiaojuan He, Masato Ishizeki, Naoki Mita, Seitaro Wada, Yoshifumi Araki, Hiroo Ogura, Manabu Abe, Maya Yamazaki, Kenji Sakimura, Katsuhiko Mikoshiba, Takafumi Inoue, Toshio Ohshim. Cdk5/p35 is required for motor coordination and cerebellar plasticity. Journal of neurochemistry. vol 131. issue 1. 2014-11-21. PMID:24802945. therefore, we created purkinje cell-specific conditional cdk5/p35 knockout (l7-p35 cko) mice, analyzed the cerebellar histology and purkinje cell morphology of these mice, evaluated their performance with balance beam and rota-rod test, and performed electrophysiological recordings to assess long-term synaptic plasticity. 2014-11-21 2023-08-13 mouse
Eriko Fujita-Jimbo, Takashi Momo. Specific expression of FOXP2 in cerebellum improves ultrasonic vocalization in heterozygous but not in homozygous Foxp2 (R552H) knock-in pups. Neuroscience letters. vol 566. 2014-11-11. PMID:24607928. to make clear the relationship between the role of foxp2 in the cerebellum and whistle-type usvs activity, we prepared transgenic (tg) mice specifically expressing human foxp2-myc in cerebellum (pcp2-foxp2-myc-tg mice) by using purkinje cell protein-2 (pcp2) promoter. 2014-11-11 2023-08-12 mouse
G Cheron, C Prigogine, J Cheron, J Márquez-Ruiz, R D Traub, B Da. Emergence of a 600-Hz buzz UP state Purkinje cell firing in alert mice. Neuroscience. vol 263. 2014-10-31. PMID:24440752. purkinje cell (pc) firing represents the sole output from the cerebellar cortex onto the deep cerebellar and vestibular nuclei. 2014-10-31 2023-08-12 mouse
Haiping Wang, Zunji Ke, Alexander Alimov, Mei Xu, Jacqueline A Frank, Shengyun Fang, Jia Lu. Spatiotemporal expression of MANF in the developing rat brain. PloS one. vol 9. issue 2. 2014-10-28. PMID:24587361. in the cerebellum, manf was localized in the external germinal layer (egl), purkinje cell layer (pcl), internal granule layer (igl) and the deep cerebellar nuclei (dcn). 2014-10-28 2023-08-12 rat
Chengzu Long, Chad E Grueter, Kunhua Song, Song Qin, Xiaoxia Qi, Y Megan Kong, John M Shelton, James A Richardson, Chun-Li Zhang, Rhonda Bassel-Duby, Eric N Olso. Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 31. 2014-10-03. PMID:25049392. here, we show that global or nervous system deletion of camta1 in mice causes severe ataxia with purkinje cell degeneration and cerebellar atrophy, partially resembling the consequences of haploinsufficiency of the human camta1 locus. 2014-10-03 2023-08-13 mouse
Bum Jun Kim, Daryl A Scot. Mouse model reveals the role of RERE in cerebellar foliation and the migration and maturation of Purkinje cells. PloS one. vol 9. issue 1. 2014-09-29. PMID:24466353. in the developing cerebellum, rere is expressed in the molecular layer, the purkinje cell layer and the granule cell layer but not in granule cell precursors. 2014-09-29 2023-08-12 mouse
Bum Jun Kim, Daryl A Scot. Mouse model reveals the role of RERE in cerebellar foliation and the migration and maturation of Purkinje cells. PloS one. vol 9. issue 1. 2014-09-29. PMID:24466353. during the postnatal period, rere depletion caused incomplete division of lobules i/ii and iii due to truncated development of the precentral fissure in the cerebellar vermis, abnormal development of lobule crus i and lobule crus ii in the cerebellar hemispheres due to attenuation of the intercrural fissure, and decreased levels of purkinje cell dendritic branching. 2014-09-29 2023-08-12 mouse
Bum Jun Kim, Daryl A Scot. Mouse model reveals the role of RERE in cerebellar foliation and the migration and maturation of Purkinje cells. PloS one. vol 9. issue 1. 2014-09-29. PMID:24466353. we conclude that rere-deficiency leads to delayed development of the principal fissures and delayed maturation and migration of purkinje cells during prenatal cerebellar development and abnormal cerebellar foliation and purkinje cell maturation during postnatal cerebellar development. 2014-09-29 2023-08-12 mouse
Jody L Campeau, Gengshu Wu, John R Bell, Jay Rasmussen, Valerie L Si. Early increase and late decrease of purkinje cell dendritic spine density in prion-infected organotypic mouse cerebellar cultures. PloS one. vol 8. issue 12. 2014-09-27. PMID:24312586. early increase and late decrease of purkinje cell dendritic spine density in prion-infected organotypic mouse cerebellar cultures. 2014-09-27 2023-08-12 mouse
Jody L Campeau, Gengshu Wu, John R Bell, Jay Rasmussen, Valerie L Si. Early increase and late decrease of purkinje cell dendritic spine density in prion-infected organotypic mouse cerebellar cultures. PloS one. vol 8. issue 12. 2014-09-27. PMID:24312586. indeed, six weeks after first detection of protease-resistant prion protein in tga20 mouse cerebellar slice cultures infected with rml prion strain, we found a statistically significant loss of purkinje cell dendritic spines and altered dendritic morphology in infected cultures, analogous to that seen in vivo. 2014-09-27 2023-08-12 mouse
Masanobu Kan. [Synapse elimination and functional neural circuit formation in the cerebellum]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 33. issue 3. 2014-09-25. PMID:25069248. the climbing fiber (cf) to the purkinje cell (pc) synapse in the cerebellum is a representative model of synapse elimination. 2014-09-25 2023-08-13 mouse
Karen R Armbrust, Xinming Wang, Tyisha J Hathorn, Samuel W Cramer, Gang Chen, Tao Zu, Takashi Kangas, Anastasia N Zink, Gülin Öz, Timothy J Ebner, Laura P W Ranu. Mutant β-III spectrin causes mGluR1α mislocalization and functional deficits in a mouse model of spinocerebellar ataxia type 5. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 30. 2014-09-22. PMID:25057192. we show that endogenous β-iii spectrin interacts with the metabotropic glutamate receptor 1α (mglur1α) and that mice expressing mutant β-iii spectrin have cerebellar dysfunction with altered mglur1α localization at purkinje cell dendritic spines, decreased mglur1-mediated responses, and deficient mglur1-mediated long-term potentiation. 2014-09-22 2023-08-13 mouse
Roy V Sillitoe, Nicholas A George-Jones, Kathleen J Millen, Richard Hawke. Purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher. Brain structure & function. vol 219. issue 1. 2014-09-19. PMID:23160833. purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher. 2014-09-19 2023-08-12 mouse
Roy V Sillitoe, Nicholas A George-Jones, Kathleen J Millen, Richard Hawke. Purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher. Brain structure & function. vol 219. issue 1. 2014-09-19. PMID:23160833. we conclude that although purkinje cell agenesis or selective purkinje cell death may contribute to the dreher phenotype, our data suggest that aberrant anlage patterning and granule cell development lead to purkinje cell ectopia, which ultimately causes abnormal cerebellar architecture in dreher. 2014-09-19 2023-08-12 mouse