| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jody L Campeau, Gengshu Wu, John R Bell, Jay Rasmussen, Valerie L Si. Early increase and late decrease of purkinje cell dendritic spine density in prion-infected organotypic mouse cerebellar cultures. PloS one. vol 8. issue 12. 2014-09-27. PMID:24312586. |
early increase and late decrease of purkinje cell dendritic spine density in prion-infected organotypic mouse cerebellar cultures. |
2014-09-27 |
2023-08-12 |
mouse |
| Jody L Campeau, Gengshu Wu, John R Bell, Jay Rasmussen, Valerie L Si. Early increase and late decrease of purkinje cell dendritic spine density in prion-infected organotypic mouse cerebellar cultures. PloS one. vol 8. issue 12. 2014-09-27. PMID:24312586. |
indeed, six weeks after first detection of protease-resistant prion protein in tga20 mouse cerebellar slice cultures infected with rml prion strain, we found a statistically significant loss of purkinje cell dendritic spines and altered dendritic morphology in infected cultures, analogous to that seen in vivo. |
2014-09-27 |
2023-08-12 |
mouse |
| Masanobu Kan. [Synapse elimination and functional neural circuit formation in the cerebellum]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 33. issue 3. 2014-09-25. PMID:25069248. |
the climbing fiber (cf) to the purkinje cell (pc) synapse in the cerebellum is a representative model of synapse elimination. |
2014-09-25 |
2023-08-13 |
mouse |
| Karen R Armbrust, Xinming Wang, Tyisha J Hathorn, Samuel W Cramer, Gang Chen, Tao Zu, Takashi Kangas, Anastasia N Zink, Gülin Öz, Timothy J Ebner, Laura P W Ranu. Mutant β-III spectrin causes mGluR1α mislocalization and functional deficits in a mouse model of spinocerebellar ataxia type 5. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 30. 2014-09-22. PMID:25057192. |
we show that endogenous β-iii spectrin interacts with the metabotropic glutamate receptor 1α (mglur1α) and that mice expressing mutant β-iii spectrin have cerebellar dysfunction with altered mglur1α localization at purkinje cell dendritic spines, decreased mglur1-mediated responses, and deficient mglur1-mediated long-term potentiation. |
2014-09-22 |
2023-08-13 |
mouse |
| Roy V Sillitoe, Nicholas A George-Jones, Kathleen J Millen, Richard Hawke. Purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher. Brain structure & function. vol 219. issue 1. 2014-09-19. PMID:23160833. |
purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher. |
2014-09-19 |
2023-08-12 |
mouse |
| Roy V Sillitoe, Nicholas A George-Jones, Kathleen J Millen, Richard Hawke. Purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher. Brain structure & function. vol 219. issue 1. 2014-09-19. PMID:23160833. |
we conclude that although purkinje cell agenesis or selective purkinje cell death may contribute to the dreher phenotype, our data suggest that aberrant anlage patterning and granule cell development lead to purkinje cell ectopia, which ultimately causes abnormal cerebellar architecture in dreher. |
2014-09-19 |
2023-08-12 |
mouse |
| Charanjit Kaur, Viswanathan Sivakumar, Zhirong Zou, Eng-Ang Lin. Microglia-derived proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1beta induce Purkinje neuronal apoptosis via their receptors in hypoxic neonatal rat brain. Brain structure & function. vol 219. issue 1. 2014-09-19. PMID:23262920. |
we conclude that hypoxic microglia in the neonatal cerebellum produce increased amounts of no, tnf-α and il-1β which when acting via their respective receptors could induce purkinje neuron death. |
2014-09-19 |
2023-08-12 |
rat |
| François Mouton-Liger, Ignasi Sahún, Thibault Collin, Patricia Lopes Pereira, Debora Masini, Sophie Thomas, Evelyne Paly, Sabrina Luilier, Sandra Même, Quentin Jouhault, Soumia Bennaï, Jean-Claude Beloeil, Jean-Charles Bizot, Yann Hérault, Mara Dierssen, Nicole Créa. Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome. Neurobiology of disease. vol 63. 2014-09-19. PMID:24291518. |
in particular, pcp4 is highly expressed in the purkinje cell, the sole output neuron of the cerebellum. |
2014-09-19 |
2023-08-12 |
mouse |
| Jimmie M Gmaz, Bruce E McKa. Toluene decreases Purkinje cell output by enhancing inhibitory synaptic transmission in the cerebellar cortex. Neuroscience letters. vol 560. 2014-09-08. PMID:24345417. |
in the present study, we examined the effects of toluene on cerebellar purkinje cell action potential output and inhibitory synaptic transmission onto purkinje cells using patch clamp electrophysiology in acute rat cerebellar slices. |
2014-09-08 |
2023-08-12 |
rat |
| Jimmie M Gmaz, Bruce E McKa. Toluene decreases Purkinje cell output by enhancing inhibitory synaptic transmission in the cerebellar cortex. Neuroscience letters. vol 560. 2014-09-08. PMID:24345417. |
the observed decreases in purkinje cell action potential output could contribute to toluene-evoked impairments in cerebellar and motor functions. |
2014-09-08 |
2023-08-12 |
rat |
| Wanda M Snow, Judy E Anderson, Mark Fr. Regional and genotypic differences in intrinsic electrophysiological properties of cerebellar Purkinje neurons from wild-type and dystrophin-deficient mdx mice. Neurobiology of learning and memory. vol 107. 2014-09-05. PMID:24220092. |
moreover, these results highlight the importance of distinguishing functional zones of the cerebellum in future work characterizing purkinje neuron electrophysiology and studies using the model of dissociated purkinje neurons from mice. |
2014-09-05 |
2023-08-12 |
mouse |
| Astrid Bergerot, Mark Rigby, Guy Bouvier, Païkan Marcagg. Persistent posttetanic depression at cerebellar parallel fiber to Purkinje cell synapses. PloS one. vol 8. issue 7. 2014-08-21. PMID:23922966. |
persistent posttetanic depression at cerebellar parallel fiber to purkinje cell synapses. |
2014-08-21 |
2023-08-12 |
mouse |
| Astrid Bergerot, Mark Rigby, Guy Bouvier, Païkan Marcagg. Persistent posttetanic depression at cerebellar parallel fiber to Purkinje cell synapses. PloS one. vol 8. issue 7. 2014-08-21. PMID:23922966. |
plasticity at the cerebellar parallel fiber to purkinje cell synapse may underlie information processing and motor learning. |
2014-08-21 |
2023-08-12 |
mouse |
| Hadi Kazemi, Erwin-Josef Speckmann, Ali Gorj. Familial hemiplegic migraine and spreading depression. Iranian journal of child neurology. vol 8. issue 3. 2014-08-21. PMID:25143767. |
fhm1 with ataxia is attributable to specific mutations that differ from mutations that cause pure fhm1 and have peculiar consequences on cerebellar cav2.1 currents that lead to profound purkinje cell dysfunction and neuronal loss with atrophy. |
2014-08-21 |
2023-08-13 |
mouse |
| Joshua J White, Marife Arancillo, Trace L Stay, Nicholas A George-Jones, Sabrina L Levy, Detlef H Heck, Roy V Sillito. Cerebellar zonal patterning relies on Purkinje cell neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 24. 2014-08-04. PMID:24920627. |
cerebellar zonal patterning relies on purkinje cell neurotransmission. |
2014-08-04 |
2023-08-13 |
mouse |
| Joshua J White, Marife Arancillo, Trace L Stay, Nicholas A George-Jones, Sabrina L Levy, Detlef H Heck, Roy V Sillito. Cerebellar zonal patterning relies on Purkinje cell neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 24. 2014-08-04. PMID:24920627. |
using in vivo electrophysiology, we demonstrate that loss of purkinje cell communication altered the firing rate and pattern of their target cerebellar nuclear neurons. |
2014-08-04 |
2023-08-13 |
mouse |
| Joshua J White, Marife Arancillo, Trace L Stay, Nicholas A George-Jones, Sabrina L Levy, Detlef H Heck, Roy V Sillito. Cerebellar zonal patterning relies on Purkinje cell neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 24. 2014-08-04. PMID:24920627. |
our results suggest that purkinje cell inhibitory neurotransmission establishes the functional circuitry of the cerebellum by patterning the molecular zones, fine-tuning afferent circuitry, and shaping neuronal activity. |
2014-08-04 |
2023-08-13 |
mouse |
| Pradeep Sherkhane, Josef P Kapfhamme. The plasma membrane Ca2+-ATPase2 (PMCA2) is involved in the regulation of Purkinje cell dendritic growth in cerebellar organotypic slice cultures. Neural plasticity. vol 2013. 2014-07-22. PMID:24288624. |
the plasma membrane ca2+-atpase2 (pmca2) is involved in the regulation of purkinje cell dendritic growth in cerebellar organotypic slice cultures. |
2014-07-22 |
2023-08-12 |
Not clear |
| Pradeep Sherkhane, Josef P Kapfhamme. The plasma membrane Ca2+-ATPase2 (PMCA2) is involved in the regulation of Purkinje cell dendritic growth in cerebellar organotypic slice cultures. Neural plasticity. vol 2013. 2014-07-22. PMID:24288624. |
chronic activation of type i metabotropic glutamate receptors inhibits purkinje cell dendritic growth in organotypic cerebellar slice cultures. |
2014-07-22 |
2023-08-12 |
Not clear |
| Mohammad Hosseini-Sharifabad, Abdoreza Sabah. Stereological estimation of granule cell number and purkinje cell volume in the cerebellum of noise-exposed young rat. Iranian journal of medical sciences. vol 39. issue 4. 2014-07-17. PMID:25031492. |
stereological estimation of granule cell number and purkinje cell volume in the cerebellum of noise-exposed young rat. |
2014-07-17 |
2023-08-13 |
rat |