| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Ghetti, K W Perry, R W Fulle. Norepinephrine metabolism in the cerebellum of the purkinje cell degeneration (pcd) mutant mouse. Neurochemistry international. vol 10. issue 1. 2012-10-02. PMID:20501080. |
the purpose of this study was to determine if cerebellar ne turnover is altered after purkinje cell loss. |
2012-10-02 |
2023-08-12 |
mouse |
| B Ghetti, K W Perry, R W Fulle. Norepinephrine metabolism in the cerebellum of the purkinje cell degeneration (pcd) mutant mouse. Neurochemistry international. vol 10. issue 1. 2012-10-02. PMID:20501080. |
we conclude that although na axons in the cerebellum are maintained in pcd mice after purkinje cell degeneration, ne turnover is decreased, suggesting that the synthesis and release of neurotransmitter does not continue at normal rates when the target cells have degenerated. |
2012-10-02 |
2023-08-12 |
mouse |
| Mohd Asnizam Asari, Mohammad Shukri Abdullah, Suryati Abdulla. Effect of early neonatal exposure to deltamethrin on the purkinje cell number in rat cerebellum. The Malaysian journal of medical sciences : MJMS. vol 15. issue 3. 2012-10-02. PMID:22570585. |
effect of early neonatal exposure to deltamethrin on the purkinje cell number in rat cerebellum. |
2012-10-02 |
2023-08-12 |
rat |
| T Tsubota, Y Ohashi, K Tamura, Y Miyashit. Optogenetic inhibition of Purkinje cell activity reveals cerebellar control of blood pressure during postural alterations in anesthetized rats. Neuroscience. vol 210. 2012-09-21. PMID:22441034. |
optogenetic inhibition of purkinje cell activity reveals cerebellar control of blood pressure during postural alterations in anesthetized rats. |
2012-09-21 |
2023-08-12 |
rat |
| Masanobu Kano, Kouichi Hashimot. Activity-dependent maturation of climbing fiber to Purkinje cell synapses during postnatal cerebellar development. Cerebellum (London, England). vol 11. issue 2. 2012-09-19. PMID:22194041. |
activity-dependent maturation of climbing fiber to purkinje cell synapses during postnatal cerebellar development. |
2012-09-19 |
2023-08-12 |
mouse |
| Kazuyoshi Tsutsu. Neurosteroid biosynthesis and action during cerebellar development. Cerebellum (London, England). vol 11. issue 2. 2012-09-19. PMID:22198872. |
in the middle 1990s, we identified the purkinje cell, a principal cerebellar neuron, as a major site for neurosteroid formation in mammals. |
2012-09-19 |
2023-08-12 |
Not clear |
| Kazuyoshi Tsutsu. Neurosteroid biosynthesis and action during cerebellar development. Cerebellum (London, England). vol 11. issue 2. 2012-09-19. PMID:22198872. |
based on extensive studies on mammals over the past decade, we now know that the purkinje cell actively synthesizes progesterone and estradiol de novo from cholesterol during neonatal life, when cerebellar neuronal circuit formation occurs. |
2012-09-19 |
2023-08-12 |
Not clear |
| Kazuyoshi Tsutsu. Neurosteroid biosynthesis and action during cerebellar development. Cerebellum (London, England). vol 11. issue 2. 2012-09-19. PMID:22198872. |
allopregnanolone, a progesterone metabolite, is also synthesized in the cerebellum and acts on purkinje cell survival in the neonate. |
2012-09-19 |
2023-08-12 |
Not clear |
| Kazuyoshi Tsutsu. Neurosteroid biosynthesis and action during cerebellar development. Cerebellum (London, England). vol 11. issue 2. 2012-09-19. PMID:22198872. |
this paper highlights the biosynthesis and biological actions of neurosteroids in the purkinje cell during cerebellar development. |
2012-09-19 |
2023-08-12 |
Not clear |
| Shogo Haraguchi, Katsunori Sasahara, Hanako Shikimi, Shin-ichiro Honda, Nobuhiro Harada, Kazuyoshi Tsutsu. Estradiol promotes purkinje dendritic growth, spinogenesis, and synaptogenesis during neonatal life by inducing the expression of BDNF. Cerebellum (London, England). vol 11. issue 2. 2012-09-19. PMID:22198873. |
in rodents, the purkinje cell actively produces several kinds of neurosteroids including estradiol during neonatal life, when cerebellar neuronal circuit formation occurs. |
2012-09-19 |
2023-08-12 |
mouse |
| Shogo Haraguchi, Katsunori Sasahara, Hanako Shikimi, Shin-ichiro Honda, Nobuhiro Harada, Kazuyoshi Tsutsu. Estradiol promotes purkinje dendritic growth, spinogenesis, and synaptogenesis during neonatal life by inducing the expression of BDNF. Cerebellum (London, England). vol 11. issue 2. 2012-09-19. PMID:22198873. |
estradiol may be involved in cerebellar neuronal circuit formation through promoting neuronal growth and synaptic contact, because the purkinje cell expresses estrogen receptor-β. |
2012-09-19 |
2023-08-12 |
mouse |
| Yasushi Iwasaki, Keiko Mori, Masumi Ito, Maya Mimuro, Mari Yoshid. [An autopsied case of progressive supranuclear palsy presenting with slow progression and unusually prolonged disease duration]. Rinsho shinkeigaku = Clinical neurology. vol 52. issue 3. 2012-08-23. PMID:22453039. |
the purkinje neuron layer and cerebellar dentate nucleus showed mild neuron loss. |
2012-08-23 |
2023-08-12 |
Not clear |
| Kazuyoshi Tsutsui, Kazuyoshi Ukena, Hirotaka Sakamoto, Shin-Ichiro Okuyama, Shogo Haraguch. Biosynthesis, mode of action, and functional significance of neurosteroids in the purkinje cell. Frontiers in endocrinology. vol 2. 2012-08-23. PMID:22654818. |
in the middle 1990s, the purkinje cell, an important cerebellar neuron, was identified as a major site for neurosteroid formation in the brain of mammals and other vertebrates. |
2012-08-23 |
2023-08-12 |
Not clear |
| Kazuyoshi Tsutsui, Kazuyoshi Ukena, Hirotaka Sakamoto, Shin-Ichiro Okuyama, Shogo Haraguch. Biosynthesis, mode of action, and functional significance of neurosteroids in the purkinje cell. Frontiers in endocrinology. vol 2. 2012-08-23. PMID:22654818. |
based on the studies on mammals over the past decade, it is considered that the purkinje cell actively synthesizes progesterone and estradiol from cholesterol during neonatal life, when cerebellar neuronal circuit formation occurs. |
2012-08-23 |
2023-08-12 |
Not clear |
| Kazuyoshi Tsutsui, Kazuyoshi Ukena, Hirotaka Sakamoto, Shin-Ichiro Okuyama, Shogo Haraguch. Biosynthesis, mode of action, and functional significance of neurosteroids in the purkinje cell. Frontiers in endocrinology. vol 2. 2012-08-23. PMID:22654818. |
this review summarizes the current knowledge regarding the biosynthesis, mode of action, and functional significance of neurosteroids in the purkinje cell during development in terms of synaptic formation of cerebellar neuronal networks. |
2012-08-23 |
2023-08-12 |
Not clear |
| Douglas R Wylie, Janelle M P Pakan, Hang Huynh, David J Graham, Andrew N Iwaniu. Distribution of zebrin-immunoreactive Purkinje cell terminals in the cerebellar and vestibular nuclei of birds. The Journal of comparative neurology. vol 520. issue 7. 2012-08-17. PMID:22105608. |
distribution of zebrin-immunoreactive purkinje cell terminals in the cerebellar and vestibular nuclei of birds. |
2012-08-17 |
2023-08-12 |
rat |
| Marta Florio, Ketty Leto, Luca Muzio, Andrea Tinterri, Aurora Badaloni, Laura Croci, Paola Zordan, Valeria Barili, Ilaria Albieri, François Guillemot, Ferdinando Rossi, G Giacomo Consale. Neurogenin 2 regulates progenitor cell-cycle progression and Purkinje cell dendritogenesis in cerebellar development. Development (Cambridge, England). vol 139. issue 13. 2012-08-15. PMID:22669821. |
neurogenin 2 regulates progenitor cell-cycle progression and purkinje cell dendritogenesis in cerebellar development. |
2012-08-15 |
2023-08-12 |
mouse |
| Elan D Louis, Phyllis L Faust, Karen J Ma, Mia Yu, Etty Cortes, Jean-Paul G Vonsatte. Torpedoes in the cerebellar vermis in essential tremor cases vs. controls. Cerebellum (London, England). vol 10. issue 4. 2012-08-13. PMID:21656041. |
the study of the postmortem changes in essential tremor (et) is in its infancy, although recent evidence points to a central role of the cerebellum, where purkinje cell axonal swellings ("torpedoes") are significantly more common in et than control brains. |
2012-08-13 |
2023-08-12 |
Not clear |
| Christine M Pedroaren. BK and Kv3.1 potassium channels control different aspects of deep cerebellar nuclear neurons action potentials and spiking activity. Cerebellum (London, England). vol 10. issue 4. 2012-08-13. PMID:21750937. |
these properties are thought to be relevant to processing inhibitory purkinje cell input and transferring well-timed signals to cerebellar targets. |
2012-08-13 |
2023-08-12 |
mouse |
| Josef P Kapfhammer, Olivia S Gugge. The analysis of purkinje cell dendritic morphology in organotypic slice cultures. Journal of visualized experiments : JoVE. issue 61. 2012-07-13. PMID:22473312. |
organotypic cerebellar slice cultures cells allow easy experimental manipulation of purkinje cell dendritic development because most of the dendritic expansion of the purkinje cell dendritic tree is actually taking place during the culture period (4). |
2012-07-13 |
2023-08-12 |
mouse |