All Relations between cerebellum purkinje cell and cerebellum

Publication Sentence Publish Date Extraction Date Species
Tabita Kreko-Pierce, Jason R Pug. Altered Synaptic Transmission and Excitability of Cerebellar Nuclear Neurons in a Mouse Model of Duchenne Muscular Dystrophy. Frontiers in cellular neuroscience. vol 16. 2022-07-22. PMID:35865113. in this work, we investigate potential dysfunction in the output of the cerebellum, downstream of purkinje cell (pc) activity. 2022-07-22 2023-08-14 mouse
Yuning Liu, Hong Xing, Alexis F Ernst, Canna Liu, Christian Maugee, Fumiaki Yokoi, Madepalli Lakshmana, Yuqing L. Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout mice. Molecular and cellular neurosciences. 2022-07-17. PMID:35843530. manipulating the purkinje cell firing or cerebellar output may contribute to c9orf72-associated als/ftd treatment. 2022-07-17 2023-08-14 mouse
Victor Olmos, Neha Gogia, Kimberly Luttik, Fatema Haidery, Janghoo Li. The extra-cerebellar effects of spinocerebellar ataxia type 1 (SCA1): looking beyond the cerebellum. Cellular and molecular life sciences : CMLS. vol 79. issue 8. 2022-07-08. PMID:35802260. however, until recently, sca1 research has primarily centered on the cerebellum, given the characteristic cerebellar purkinje cell loss observed in patients, as well as the progressive motor deficits, including gait and limb incoordination, that sca1 patients present with. 2022-07-08 2023-08-14 mouse
David D Bushart, Vikram G Shakkotta. Vulnerability of Human Cerebellar Neurons to Degeneration in Ataxia-Causing Channelopathies. Frontiers in systems neuroscience. vol 16. 2022-06-27. PMID:35757096. human ataxia-causing channelopathies that result in even haploinsufficiency can result in cerebellar atrophy and cerebellar purkinje neuron loss. 2022-06-27 2023-08-14 mouse
Eric J Lang, Adrian Handfort. Is the inferior olive central to essential tremor? Yes. International review of neurobiology. vol 163. 2022-06-24. PMID:35750361. much evidence shows that the olivocerebellar system is the main system capable of generating the widespread synchronous oscillatory purkinje cell (pc) complex spike (cs) activity across the cerebellar cortex that would be capable of generating the type of bursting cerebellar output from the deep cerebellar nuclei (dcn) that could underlie tremor. 2022-06-24 2023-08-14 mouse
Steven Bellows, Joohi Jimenez-Shahe. Is essential tremor a disorder of GABA dysfunction? No. International review of neurobiology. vol 163. 2022-06-24. PMID:35750366. hypersynchrony of purkinje cell activity may account for excessive oscillatory cerebellar output, with potential contributions along multiple sites of the olivocerebellar loop. 2022-06-24 2023-08-14 mouse
Phyllis L Faus. Is essential tremor a degenerative disorder or an electric disorder? Degenerative disorder. International review of neurobiology. vol 163. 2022-06-24. PMID:35750370. most of these pathological changes are centered on the purkinje cell and connected neuronal populations, which can result in partial loss of purkinje cells and circuitry reorganizations that would disturb cerebellar function. 2022-06-24 2023-08-14 Not clear
Kazuyuki Miyamoto, Motoyasu Nakamura, Hirokazu Ohtaki, Keisuke Suzuki, Hiroki Yamaga, Kaoru Yanagisawa, Atsuo Maeda, Masaharu Yagi, Munetaka Hayashi, Kazuho Honda, Kenji Doh. Heatstroke-induced late-onset neurological deficits in mice caused by white matter demyelination, Purkinje cell degeneration, and synaptic impairment in the cerebellum. Scientific reports. vol 12. issue 1. 2022-06-22. PMID:35732789. heatstroke-induced late-onset neurological deficits in mice caused by white matter demyelination, purkinje cell degeneration, and synaptic impairment in the cerebellum. 2022-06-22 2023-08-14 mouse
Harry T Or. Cholecystokinin Activation of Cholecystokinin 1 Receptors: a Purkinje Cell Neuroprotective Pathway. Cerebellum (London, England). 2022-06-22. PMID:35733029. this is a summary of the virtual presentation given at the 2021 meeting of the society for research on the cerebellum and ataxias, https://www.meetings.be/srca2021/ , where the therapeutic potential of the cck-cck1r pathway for treating diseases involving purkinje cell degeneration was presented. 2022-06-22 2023-08-14 mouse
Andrea Pirone, Chiara Magliaro, Carlo Cantile, Carla Lenzi, Alessandra Coli, Vincenzo Miragliott. Comparative and quantitative morphology of the pig and wild boar cerebellum for identifying possible effects of domestication. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 2022-06-01. PMID:35644466. our results showed that: (i) the foliation index, expressing the rate of cerebellar cortical folding, and the number of granular cells were not significantly different between pigs and wild boars; (ii) area of the granular layer and the molecular layer, and area of white matter were lower in pigs; (iii) the fraction area, grey matter/white matter, was higher in pigs; (iv) the purkinje cell linear density and their soma area were higher in wild boars. 2022-06-01 2023-08-13 human
Xiu-Xiu Liu, Xing-Hui Chen, Zhi-Wei Zheng, Qin Jiang, Chen Li, Lin Yang, Xiang Chen, Xing-Feng Mao, Hao-Yang Yuan, Li-Li Feng, Quan Jiang, Wei-Xing Shi, Takuya Sasaki, Kohji Fukunaga, Zhong Chen, Feng Han, Ying-Mei L. BOD1 regulates the cerebellar IV/V lobe-fastigial nucleus circuit associated with motor coordination. Signal transduction and targeted therapy. vol 7. issue 1. 2022-05-31. PMID:35641478. through cell-type-specific manipulations, we discovered a novel gabaergic purkinje cell (pc) circuit in the cerebellar iv/v lobe that projected to camkiiα 2022-05-31 2023-08-13 Not clear
Eric Avila, Nico A Flierman, Peter J Holland, Pieter R Roelfsema, Maarten A Frens, Aleksandra Badura, Chris I De Zeeu. Purkinje Cell Activity in the Medial and Lateral Cerebellum During Suppression of Voluntary Eye Movements in Rhesus Macaques. Frontiers in cellular neuroscience. vol 16. 2022-05-16. PMID:35573834. purkinje cell activity in the medial and lateral cerebellum during suppression of voluntary eye movements in rhesus macaques. 2022-05-16 2023-08-13 Not clear
Eric Avila, Nico A Flierman, Peter J Holland, Pieter R Roelfsema, Maarten A Frens, Aleksandra Badura, Chris I De Zeeu. Purkinje Cell Activity in the Medial and Lateral Cerebellum During Suppression of Voluntary Eye Movements in Rhesus Macaques. Frontiers in cellular neuroscience. vol 16. 2022-05-16. PMID:35573834. here, we measured purkinje cell (pc) responses in the medial and lateral cerebellum in two rhesus macaques during pro- and anti-saccade tasks. 2022-05-16 2023-08-13 Not clear
Xiaofan Yang, Hongqiang Yin, Xiaojing Wang, Yueqing Sun, Xianli Bian, Gaorui Zhang, Anning Li, Aihua Cao, Baomin Li, Darius Ebrahimi-Fakhari, Zhuo Yang, Miriam H Meisler, Qiji Li. Social Deficits and Cerebellar Degeneration in Purkinje Cell Frontiers in molecular neuroscience. vol 15. 2022-05-13. PMID:35557557. social deficits and cerebellar degeneration in purkinje cell mutations in the 2022-05-13 2023-08-13 Not clear
Omid A Zobeiri, Kathleen E Culle. Distinct representations of body and head motion are dynamically encoded by Purkinje cell populations in the macaque cerebellum. eLife. vol 11. 2022-04-25. PMID:35467528. distinct representations of body and head motion are dynamically encoded by purkinje cell populations in the macaque cerebellum. 2022-04-25 2023-08-13 monkey
Michael A Gaffield, Britton A Sauerbrei, Jason M Christi. Cerebellum encodes and influences the initiation, performance, and termination of discontinuous movements in mice. eLife. vol 11. 2022-04-22. PMID:35451957. to provide functional evidence validating this idea, we measured and manipulated purkinje cell (pc) activity in the lateral cerebellum of mice trained to volitionally perform periodic bouts of licking for regularly allocated water rewards. 2022-04-22 2023-08-13 mouse
Marion Coolen, Nami Altin, Karthyayani Rajamani, Eva Pereira, Karine Siquier-Pernet, Emilia Puig Lombardi, Nadjeda Moreno, Giulia Barcia, Marianne Yvert, Annie Laquerrière, Aurore Pouliet, Patrick Nitschké, Nathalie Boddaert, Antonio Rausell, Féréchté Razavi, Alexandra Afenjar, Thierry Billette de Villemeur, Almundher Al-Maawali, Khalid Al-Thihli, Julia Baptista, Ana Beleza-Meireles, Catherine Garel, Marine Legendre, Antoinette Gelot, Lydie Burglen, Sébastien Moutton, Vincent Cantagre. Recessive PRDM13 mutations cause fatal perinatal brainstem dysfunction with cerebellar hypoplasia and disrupt Purkinje cells differentiation. American journal of human genetics. 2022-04-07. PMID:35390279. notably, histopathological examinations highlighted a sparse and disorganized purkinje cell layer in the cerebellum. 2022-04-07 2023-08-13 mouse
Ehsan Sedaghat-Nejad, Jay S Pi, Paul Hage, Mohammad Amin Fakharian, Reza Shadmeh. Synchronous spiking of cerebellar Purkinje cells during control of movements. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 14. 2022-03-29. PMID:35349338. here we report that, in the cerebellum, purkinje cell populations that share a preference for error convey, to the nucleus, when to decelerate the movement, by reducing their firing rates and temporally synchronizing the remaining spikes. 2022-03-29 2023-08-13 Not clear
Tuancheng Feng, Lin Luan, Isabel Iscol Katz, Mohammed Ullah, Vivianna M Van Deerlin, John Q Trojanowski, Edward B Lee, Fenghua H. TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss. Acta neuropathologica communications. vol 10. issue 1. 2022-03-15. PMID:35287730. tmem106b deficiency impairs cerebellar myelination and synaptic integrity with purkinje cell loss. 2022-03-15 2023-08-13 mouse
Yasmin Fidler, Jose Rosa Gome. Effects of a Single Dose of X-Ray Irradiation on MMP-9 Expression and Morphology of the Cerebellum Cortex of Adult Rats. Cerebellum (London, England). 2022-03-09. PMID:35262839. we conclude that the effects of a single dose of 15-gy x-ray irradiation in the cerebellum were an increase in mmp-9 expression in the first 2 weeks after irradiation, especially surrounding the purkinje cells and in the molecular layers, with morphological changes in the purkinje cell and granular cell layers, suggesting a continuous cell loss throughout the days evaluated after irradiation. 2022-03-09 2023-08-13 rat