| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Joshua Langmade, Sarah E Gale, Andrey Frolov, Ikuko Mohri, Kinuko Suzuki, Synthia H Mellon, Steven U Walkley, Douglas F Covey, Jean E Schaffer, Daniel S Or. Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 37. 2006-10-30. PMID:16940355. |
niemann-pick type c1 (npc1) disease is a fatal neurodegenerative disease characterized by neuronal lipid storage and progressive purkinje cell loss in the cerebellum. |
2006-10-30 |
2023-08-12 |
mouse |
| Deanna L Taylor, Umesh C Joashi, Catherine Sarraf, A David Edwards, Huseyin Mehme. Consequential apoptosis in the cerebellum following injury to the developing rat forebrain. Brain pathology (Zurich, Switzerland). vol 16. issue 3. 2006-10-25. PMID:16911476. |
injury to the rat forebrain following hypoxia-ischemia increased apoptosis in the internal granular and purkinje cell layers of the cerebellum, a site distant to that of the primary injury. |
2006-10-25 |
2023-08-12 |
rat |
| A Blanco, R Moyano, J Vivo, R Flores-Acuña, A Molina, C Blanco, J G Monterd. Purkinje cell apoptosis in arabian horses with cerebellar abiotrophy. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine. vol 53. issue 6. 2006-10-10. PMID:16901270. |
purkinje cell apoptosis in arabian horses with cerebellar abiotrophy. |
2006-10-10 |
2023-08-12 |
Not clear |
| Alexander Fisyunov, Vera Tsintsadze, Rogier Min, Nail Burnashev, Natalia Lozovay. Cannabinoids modulate the P-type high-voltage-activated calcium currents in purkinje neurons. Journal of neurophysiology. vol 96. issue 3. 2006-10-06. PMID:16738209. |
in particular, in the cerebellum, endocannabinoids inhibit synaptic transmission at granule cell to purkinje cell synapses by modulating presynaptic calcium influx via n-, p/q-, and r-type calcium channels. |
2006-10-06 |
2023-08-12 |
rat |
| Holly B Kordasiewicz, Randall M Thompson, H Brent Clark, Christopher M Gome. C-termini of P/Q-type Ca2+ channel alpha1A subunits translocate to nuclei and promote polyglutamine-mediated toxicity. Human molecular genetics. vol 15. issue 10. 2006-10-03. PMID:16595610. |
antiserum to the c-terminus (ct-2) labels both wild-type mouse and human purkinje cell nuclei, but not leaner mouse cerebellum. |
2006-10-03 |
2023-08-12 |
mouse |
| Søren Warming, Rivka A Rachel, Nancy A Jenkins, Neal G Copelan. Zfp423 is required for normal cerebellar development. Molecular and cellular biology. vol 26. issue 18. 2006-09-28. PMID:16943432. |
in mice carrying a hypomorphic zfp423 gene trap allele, lacz expression in the cerebellum correlates with the purkinje cell layer, suggesting that these phenotypes are a result of a purkinje cell-intrinsic defect. |
2006-09-28 |
2023-08-12 |
mouse |
| Ying-Jie Sun, Kaori Nishikawa, Hideki Yuda, Yu-Lai Wang, Hitoshi Osaka, Nobuna Fukazawa, Akira Naito, Yoshihisa Kudo, Keiji Wada, Shunsuke Aok. Solo/Trio8, a membrane-associated short isoform of Trio, modulates endosome dynamics and neurite elongation. Molecular and cellular biology. vol 26. issue 18. 2006-09-28. PMID:16943433. |
with dna microarrays, we identified a gene, termed solo, that is downregulated in the cerebellum of purkinje cell degeneration mutant mice. |
2006-09-28 |
2023-08-12 |
mouse |
| Yahong Zhang, Yin-Xian Pan, Yuri Kolesnikov, Gavril W Pasterna. Immunohistochemical labeling of the mu opioid receptor carboxy terminal splice variant mMOR-1B4 in the mouse central nervous system. Brain research. vol 1099. issue 1. 2006-09-19. PMID:16793025. |
some of the structures showing prominent mmor-1b4-li include the olfactory bulb, cerebral cortex, bed nucleus of stria terminalis, hippocampus, habenular nucleus, amygdala, thalamus, hypothalamus, medium eminence, substantia nigra, ventral tegmental area, oculomotor nucleus, red nucleus, raphe nuclei, periaqueductal gray, locus coeruleus, trigeminal nucleus, reticular formation, area postrema and purkinje cell layer and deep nuclei of cerebellum. |
2006-09-19 |
2023-08-12 |
mouse |
| Virginie Sottile, Meng Li, Paul J Scottin. Stem cell marker expression in the Bergmann glia population of the adult mouse brain. Brain research. vol 1099. issue 1. 2006-09-19. PMID:16797497. |
in situ hybridization and the use of a transgenic mouse model show that, in the adult cerebellum, sox 1 is only expressed in the bergmann glia, a population of radial glia present in the purkinje cell layer. |
2006-09-19 |
2023-08-12 |
mouse |
| Laura Croci, Seung-Hyuk Chung, Giacomo Masserdotti, Sara Gianola, Antonella Bizzoca, Gianfranco Gennarini, Anna Corradi, Ferdinando Rossi, Richard Hawkes, G Giacomo Consale. A key role for the HLH transcription factor EBF2COE2,O/E-3 in Purkinje neuron migration and cerebellar cortical topography. Development (Cambridge, England). vol 133. issue 14. 2006-09-18. PMID:16774995. |
a key role for the hlh transcription factor ebf2coe2,o/e-3 in purkinje neuron migration and cerebellar cortical topography. |
2006-09-18 |
2023-08-12 |
mouse |
| S Hadi Zanjani, Fekrije Selimi, Michael W Vogel, Anne-Marie Haeberlé, Julien Boeuf, Jean Mariani, Yannick J Baill. Survival of interneurons and parallel fiber synapses in a cerebellar cortex deprived of Purkinje cells: studies in the double mutant mouse Grid2Lc/+;Bax(-/-). The Journal of comparative neurology. vol 497. issue 4. 2006-09-11. PMID:16739195. |
given the larger size of the cerebellar molecular layer in grid2lc/+;bax(-/-) double mutants compared to grid2lc/+ mutants, we analyzed the survival of the stellate and basket interneurons as well as the synaptic connectivity of parallel fibers originating from the surviving granule cells in the absence of their purkinje cell targets in the grid2lc/+;bax(-/-) cerebellum. |
2006-09-11 |
2023-08-12 |
mouse |
| L Zhu, B Scelfo, F Tempia, B Sacchetti, P Strat. Membrane excitability and fear conditioning in cerebellar Purkinje cell. Neuroscience. vol 140. issue 3. 2006-09-08. PMID:16580140. |
since modifications of intrinsic membrane properties have been suggested to mediate some forms of memory processes, we investigated possible changes of purkinje cell intrinsic properties following the same learning paradigm and in the same cerebellar region. |
2006-09-08 |
2023-08-12 |
rat |
| Ferdinando Rossi, Filippo Tempi. Unravelling the Purkinje neuron. Cerebellum (London, England). vol 5. issue 2. 2006-09-08. PMID:16818381. |
this special issue of the cerebellum is dedicated to this very special neuron and contains a number of articles covering different topics of purkinje cell research, from developmental neurobiology to neurophysiology and neuropathology. |
2006-09-08 |
2023-08-12 |
Not clear |
| Matt Larouche, Richard Hawke. From clusters to stripes: the developmental origins of adult cerebellar compartmentation. Cerebellum (London, England). vol 5. issue 2. 2006-09-08. PMID:16818382. |
purkinje cells are the best-studied example of parasagittal organization in the cerebellum and, in particular, zebrin ii/aldolase c is the stereotypical molecular marker of purkinje cell stripe heterogeneity in the adult. |
2006-09-08 |
2023-08-12 |
mouse |
| Matt Larouche, Richard Hawke. From clusters to stripes: the developmental origins of adult cerebellar compartmentation. Cerebellum (London, England). vol 5. issue 2. 2006-09-08. PMID:16818382. |
in contrast, 'early-onset' pattern markers are expressed in ordered purkinje cell clusters in the embryonic cerebellum but become expressed homogeneously shortly after birth. |
2006-09-08 |
2023-08-12 |
mouse |
| Kazuyoshi Tsutsu. Biosynthesis and organizing action of neurosteroids in the developing Purkinje cell. Cerebellum (London, England). vol 5. issue 2. 2006-09-08. PMID:16818383. |
recently the purkinje cell, a cerebellar neuron, has been identified as a major site for neurosteroid formation in the brain. |
2006-09-08 |
2023-08-12 |
Not clear |
| Kazuyoshi Tsutsu. Biosynthesis and organizing action of neurosteroids in the developing Purkinje cell. Cerebellum (London, England). vol 5. issue 2. 2006-09-08. PMID:16818383. |
in mammals, the purkinje cell actively synthesizes progesterone de novo from cholesterol during neonatal life, when cerebellar cortical formation occurs. |
2006-09-08 |
2023-08-12 |
Not clear |
| Kazuyoshi Tsutsu. Biosynthesis and organizing action of neurosteroids in the developing Purkinje cell. Cerebellum (London, England). vol 5. issue 2. 2006-09-08. PMID:16818383. |
thus the purkinje cell serves as an excellent cellular model for understanding the formation of cerebellar neuronal circuit in relation to organizing actions of neurosteroids. |
2006-09-08 |
2023-08-12 |
Not clear |
| Isabelle Dusart, Jean Louis Guenet, Constantino Sotel. Purkinje cell death: differences between developmental cell death and neurodegenerative death in mutant mice. Cerebellum (London, England). vol 5. issue 2. 2006-09-08. PMID:16818391. |
this review is devoted to purkinje cell death occurring during development and in spontaneous cerebellar mutations of the mouse. |
2006-09-08 |
2023-08-12 |
mouse |
| J B Tian, X Shan, G A Bishop, J S Kin. Presynaptic localization of a truncated isoform of the type 2 corticotropin releasing factor receptor in the cerebellum. Neuroscience. vol 138. issue 2. 2006-08-16. PMID:16413121. |
immunoreactivity is evident in the basal region of many, but not all purkinje cell bodies and their initial axonal segments, as well as the initial axonal segments of isolated golgi cells, and cerebellar nuclear neurons. |
2006-08-16 |
2023-08-12 |
mouse |