| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shinji Matsuda, Keiko Matsuda, Michisuke Yuzak. A new motif necessary and sufficient for stable localization of the delta2 glutamate receptors at postsynaptic spines. The Journal of biological chemistry. vol 281. issue 25. 2006-08-11. PMID:16636065. |
the delta2 glutamate receptor (glurdelta2) is abundantly expressed at the spines of purkinje cell dendrites and controls synaptic plasticity in the cerebellum. |
2006-08-11 |
2023-08-12 |
Not clear |
| Maike Glitsc. Selective inhibition of spontaneous but not Ca2+ -dependent release machinery by presynaptic group II mGluRs in rat cerebellar slices. Journal of neurophysiology. vol 96. issue 1. 2006-08-04. PMID:16611839. |
this study shows, using the whole cell patch-clamp technique in rat cerebellar slices, that at the interneuron- purkinje cell synapse activation of presynaptic group ii metabotropic glutamate receptors suppresses spontaneous gaba release through a mechanism independent of voltage-gated ca2+ channels, store-operated ca2+ channels, and ca2+ release from intracellular ca2+ stores, suggesting that the metabotropic receptors target the release machinery directly. |
2006-08-04 |
2023-08-12 |
rat |
| Piercesare Grimaldi, Ferdinando Ross. Lack of neurogenesis in the adult rat cerebellum after Purkinje cell degeneration and growth factor infusion. The European journal of neuroscience. vol 23. issue 10. 2006-08-04. PMID:16817868. |
lack of neurogenesis in the adult rat cerebellum after purkinje cell degeneration and growth factor infusion. |
2006-08-04 |
2023-08-12 |
rat |
| A M Ghoumari, C Piochon, C Tomkiewicz, B Eychenne, C Levenes, I Dusart, M Schumacher, E E Baulie. Neuroprotective effect of mifepristone involves neuron depolarization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 9. 2006-07-31. PMID:16816113. |
in the rat cerebellum, purkinje cell apoptosis is exacerbated when cerebellar slices are cultured during the first postnatal week. |
2006-07-31 |
2023-08-12 |
rat |
| Anaid Mees, Rebecca Rock, Francesca D Ciccarelli, Cornelia B Leberfinger, Johanna M Borawski, Peer Bork, Stefan Wiese, Manfred Gessler, Eugen Kerkhof. Very-KIND is a novel nervous system specific guanine nucleotide exchange factor for Ras GTPases. Gene expression patterns : GEP. vol 6. issue 1. 2006-07-21. PMID:16099729. |
in situ hybridizations showed a specific expression of vkind in neuronal cells of the granular and purkinje cell layers of the cerebellum. |
2006-07-21 |
2023-08-12 |
mouse |
| Laura Morando, Roberta Cesa, Robin J Harvey, Piergiorgio Strat. Spontaneous electrical activity and structural plasticity in the mature cerebellar cortex. Annals of the New York Academy of Sciences. vol 1048. 2006-07-19. PMID:16154927. |
in adult rats, after 7 days of blocked electrical activity by the administration of ttx into the cerebellar parenchyma, the proximal dendritic domain of the purkinje cell shows a remarkable growth of new spines that are innervated by parallel fibers. |
2006-07-19 |
2023-08-12 |
rat |
| T Toyoda, K Ochiai, H Hatai, M Murakami, E Ono, T Kimura, T Umemur. Cerebellar hypoplasia associated with an avian leukosis virus inducing fowl glioma. Veterinary pathology. vol 43. issue 3. 2006-07-13. PMID:16672576. |
the cerebellar anomaly included diffuse depletion of granular cells of the internal granular layer (igl), remnants of the external granular layer (egl), and disorganization of the purkinje cell layer. |
2006-07-13 |
2023-08-12 |
Not clear |
| Justyna R Sarna, Hassan Marzban, Masahiko Watanabe, Richard Hawke. Complementary stripes of phospholipase Cbeta3 and Cbeta4 expression by Purkinje cell subsets in the mouse cerebellum. The Journal of comparative neurology. vol 496. issue 3. 2006-06-29. PMID:16566000. |
complementary stripes of phospholipase cbeta3 and cbeta4 expression by purkinje cell subsets in the mouse cerebellum. |
2006-06-29 |
2023-08-12 |
mouse |
| Alexandros A Lavdas, Isabelle Franceschini, Monique Dubois-Dalcq, Rebecca Matsa. Schwann cells genetically engineered to express PSA show enhanced migratory potential without impairment of their myelinating ability in vitro. Glia. vol 53. issue 8. 2006-06-22. PMID:16598779. |
when grafted in neonatal cerebellar slices, stx-transduced cells started to myelinate purkinje cell axons like control cells and make myelin internodes after 2 to 3 weeks. |
2006-06-22 |
2023-08-12 |
rat |
| Shin-ya Kawaguchi, Tomoo Hiran. Integrin alpha3beta1 suppresses long-term potentiation at inhibitory synapses on the cerebellar Purkinje neuron. Molecular and cellular neurosciences. vol 31. issue 3. 2006-05-22. PMID:16307893. |
at the gabaergic synapses between inhibitory interneurons and a purkinje neuron (pn) in the cerebellum, the postsynaptic depolarization induces the long-term potentiation (called rebound potentiation; rp) of gabaa receptor responsiveness. |
2006-05-22 |
2023-08-12 |
Not clear |
| Cindy S Roegge, John R Morris, Sherilyn Villareal, Victor C Wang, Brian E Powers, Anna Y Klintsova, William T Greenough, Isaac N Pessah, Susan L Schant. Purkinje cell and cerebellar effects following developmental exposure to PCBs and/or MeHg. Neurotoxicology and teratology. vol 28. issue 1. 2006-05-10. PMID:16309888. |
purkinje cell and cerebellar effects following developmental exposure to pcbs and/or mehg. |
2006-05-10 |
2023-08-12 |
rat |
| Cindy S Roegge, John R Morris, Sherilyn Villareal, Victor C Wang, Brian E Powers, Anna Y Klintsova, William T Greenough, Isaac N Pessah, Susan L Schant. Purkinje cell and cerebellar effects following developmental exposure to PCBs and/or MeHg. Neurotoxicology and teratology. vol 28. issue 1. 2006-05-10. PMID:16309888. |
however, all three male exposure groups had a marginally significant increase in purkinje cell height, which may suggest a subtle thyromimetic effect in the cerebellum. |
2006-05-10 |
2023-08-12 |
rat |
| Jason E Kralic, Corinne Sidler, Franziska Parpan, Gregg E Homanics, A Leslie Morrow, Jean-Marc Fritsch. Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of gamma-aminobutyric acid type A receptor alpha1 subunit knockout mice. The Journal of comparative neurology. vol 495. issue 4. 2006-05-05. PMID:16485284. |
in the molecular layer of the cerebellum, alpha1 subunit clusters colocalized with gephyrin disappeared from purkinje cell dendrites of mutant mice, whereas alpha3 subunit/gephyrin clusters, presumably located on dendrites of golgi interneurons, increased sevenfold, suggesting profound network reorganization in the absence of the alpha1 subunit. |
2006-05-05 |
2023-08-12 |
mouse |
| Ayten Türkkani Tunç, Mehmet Turgut, Hüseyin Aslan, Bünyamin Sahin, Mine Ertem Yurtseven, Süleyman Kapla. Neonatal pinealectomy induces Purkinje cell loss in the cerebellum of the chick: a stereological study. Brain research. vol 1067. issue 1. 2006-05-02. PMID:16360649. |
neonatal pinealectomy induces purkinje cell loss in the cerebellum of the chick: a stereological study. |
2006-05-02 |
2023-08-12 |
chicken |
| Ayten Türkkani Tunç, Mehmet Turgut, Hüseyin Aslan, Bünyamin Sahin, Mine Ertem Yurtseven, Süleyman Kapla. Neonatal pinealectomy induces Purkinje cell loss in the cerebellum of the chick: a stereological study. Brain research. vol 1067. issue 1. 2006-05-02. PMID:16360649. |
in the current study, the effects of pinealectomy on purkinje cell number and morphological features of developing cerebellum in the chick were investigated using stereological methods. |
2006-05-02 |
2023-08-12 |
chicken |
| Anne-Marie Haeberlé, Francis Castets, Guy Bombarde, Gilbert Baillat, Yannick Baill. Immunogold localization of phocein in dendritic spines. The Journal of comparative neurology. vol 495. issue 3. 2006-04-28. PMID:16440294. |
in the cerebellum, phocein-bound immunogold particle numbers ranged from 1-20 in approximately 50% of the purkinje cell spines. |
2006-04-28 |
2023-08-12 |
Not clear |
| Mario Carta, Manuel Mameli, C Fernando Valenzuel. Alcohol potently modulates climbing fiber-->Purkinje neuron synapses: role of metabotropic glutamate receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 7. 2006-04-24. PMID:16481422. |
our findings identify the climbing fiber-->purkinje neuron synapse as an important target of ethanol in the cerebellar cortex and indicate that ethanol significantly affects cerebellar circuits even at concentrations as low as 10 mm (legal blood alcohol level in the united states is below 0.08 g/dl = 17 mm). |
2006-04-24 |
2023-08-12 |
rat |
| Yi Zhang, Xuenong Bo, Ralf Schoepfer, Anthony J D G Holtmaat, Joost Verhaagen, Piers C Emson, A Robert Lieberman, Patrick N Anderso. Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 41. 2006-04-20. PMID:16195382. |
transgenic mice were generated in which purkinje cells constitutively express l1 or both l1 and gap-43 under the purkinje cell-specific l7 promoter, and regeneration of purkinje cell axons into peripheral nerve grafts implanted into the cerebellum was examined. |
2006-04-20 |
2023-08-12 |
mouse |
| Joy T Walter, Karina Alviña, Mary D Womack, Carolyn Chevez, Kamran Khodakha. Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia. Nature neuroscience. vol 9. issue 3. 2006-04-14. PMID:16474392. |
decreases in the precision of purkinje cell pacemaking cause cerebellar dysfunction and ataxia. |
2006-04-14 |
2023-08-12 |
mouse |
| Randall J Roper, Laura L Baxter, Nidhi G Saran, Donna K Klinedinst, Philip A Beachy, Roger H Reeve. Defective cerebellar response to mitogenic Hedgehog signaling in Down [corrected] syndrome mice. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 5. 2006-03-21. PMID:16432181. |
these mice display a number of developmental anomalies analogous to those in ds, including a small cerebellum with a significantly decreased number of both granule and purkinje cell neurons. |
2006-03-21 |
2023-08-12 |
mouse |