| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria L Florez-McClure, Daniel A Linseman, Charleen T Chu, Phil A Barker, Ron J Bouchard, Shoshona S Le, Tracey A Laessig, Kim A Heidenreic. The p75 neurotrophin receptor can induce autophagy and death of cerebellar Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 19. 2004-08-13. PMID:15140920. |
the cellular mechanisms underlying purkinje neuron death in various neurodegenerative disorders of the cerebellum are poorly understood. |
2004-08-13 |
2023-08-12 |
Not clear |
| Paula M Lewis, Amel Gritli-Linde, Richard Smeyne, Andreas Kottmann, Andrew P McMaho. Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Developmental biology. vol 270. issue 2. 2004-08-12. PMID:15183722. |
here, we demonstrate that shh protein is present in the murine cerebellum during late stages of embryogenesis and is associated with purkinje cell bodies and their processes. |
2004-08-12 |
2023-08-12 |
mouse |
| Paula M Lewis, Amel Gritli-Linde, Richard Smeyne, Andreas Kottmann, Andrew P McMaho. Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Developmental biology. vol 270. issue 2. 2004-08-12. PMID:15183722. |
in addition, the loss of shh activity influences purkinje cell development and the formation of folia in the cerebellum. |
2004-08-12 |
2023-08-12 |
mouse |
| Marco Canepari, Céline Auger, David Ogde. Ca2+ ion permeability and single-channel properties of the metabotropic slow EPSC of rat Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 14. 2004-08-03. PMID:15071104. |
the slow epsc (sepsc) of cerebellar parallel fiber --> purkinje neuron synapses is mediated by metabotropic glutamate receptor type 1 (mglur1) activation of nonselective cation channels. |
2004-08-03 |
2023-08-12 |
rat |
| Hanako Shikimi, Hirotaka Sakamoto, Yukio Mezaki, Kazuyoshi Ukena, Kazuyoshi Tsutsu. Dendritic growth in response to environmental estrogens in the developing Purkinje cell in rats. Neuroscience letters. vol 364. issue 2. 2004-07-27. PMID:15196690. |
we have demonstrated recently that the purkinje cell actively produces sex steroids, such as estradiol and progesterone, de novo from cholesterol only during rat neonatal life, when cerebellar cortical formation occurs. |
2004-07-27 |
2023-08-12 |
rat |
| Yosuke Ando, Nobutsune Ichihara, Shigehito Takeshita, Yoshiaki Saito, Takeki Kikuchi, Noboru Wakasug. Histological and ultrastructural features in the early stage of Purkinje cell degeneration in the cerebellar calcification (CC) rat. Experimental animals. vol 53. issue 2. 2004-07-20. PMID:15153669. |
histological and ultrastructural features in the early stage of purkinje cell degeneration in the cerebellar calcification (cc) rat. |
2004-07-20 |
2023-08-12 |
rat |
| Yosuke Ando, Nobutsune Ichihara, Shigehito Takeshita, Yoshiaki Saito, Takeki Kikuchi, Noboru Wakasug. Histological and ultrastructural features in the early stage of Purkinje cell degeneration in the cerebellar calcification (CC) rat. Experimental animals. vol 53. issue 2. 2004-07-20. PMID:15153669. |
the cerebellar calcification (cc) rat is a new neurodegenerative mutant with severe purkinje cell loss and symmetrical calcifications in the cerebellar cortex manifesting ataxia: lack of coordination in body movements. |
2004-07-20 |
2023-08-12 |
rat |
| Yosuke Ando, Nobutsune Ichihara, Shigehito Takeshita, Yoshiaki Saito, Takeki Kikuchi, Noboru Wakasug. Histological and ultrastructural features in the early stage of Purkinje cell degeneration in the cerebellar calcification (CC) rat. Experimental animals. vol 53. issue 2. 2004-07-20. PMID:15153669. |
these findings suggest abnormal storage of glycoconjugates might be a trigger of purkinje cell degeneration and serves as a matrix for accumulation of calcium phosphate in the cerebellum of cc rats. |
2004-07-20 |
2023-08-12 |
rat |
| Birgitte Bo Anderse. Reduction of Purkinje cell volume in cerebellum of alcoholics. Brain research. vol 1007. issue 1-2. 2004-07-19. PMID:15064131. |
reduction of purkinje cell volume in cerebellum of alcoholics. |
2004-07-19 |
2023-08-12 |
Not clear |
| Birgitte Bo Anderse. Reduction of Purkinje cell volume in cerebellum of alcoholics. Brain research. vol 1007. issue 1-2. 2004-07-19. PMID:15064131. |
it is generally believed that chronic alcohol consumption results in cerebellar atrophy and purkinje cell loss, especially in the anterior vermal region. |
2004-07-19 |
2023-08-12 |
Not clear |
| Gabor Brasnjo, Thomas S Oti. Isolation of glutamate transport-coupled charge flux and estimation of glutamate uptake at the climbing fiber-Purkinje cell synapse. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 16. 2004-06-15. PMID:15067125. |
at climbing fiber to purkinje cell (pc) synapses in cerebellum, a fraction of released glutamate is rapidly bound and inactivated by neuronal eaats located on postsynaptic pcs. |
2004-06-15 |
2023-08-12 |
Not clear |
| J D Swinny, F Metzger, J IJkema-Paassen, N V Gounko, A Gramsbergen, J J L van der Wan. Corticotropin-releasing factor and urocortin differentially modulate rat Purkinje cell dendritic outgrowth and differentiation in vitro. The European journal of neuroscience. vol 19. issue 7. 2004-05-24. PMID:15078549. |
here, we use rat organotypic cerebellar slice cultures to investigate the roles of crf and urocortin on purkinje cell dendritic development. |
2004-05-24 |
2023-08-12 |
rat |
| Kea Joo Lee, Hyun Kim, Tae Sik Kim, Sun-Hwa Park, Im Joo Rhy. Morphological analysis of spine shapes of Purkinje cell dendrites in the rat cerebellum using high-voltage electron microscopy. Neuroscience letters. vol 359. issue 1-2. 2004-05-21. PMID:15050702. |
morphological analysis of spine shapes of purkinje cell dendrites in the rat cerebellum using high-voltage electron microscopy. |
2004-05-21 |
2023-08-12 |
rat |
| Nikolina Basić-Jukić, Petar Kes, Vanja Basić-Kes, Bruna Brunett. [Importance of plasmapheresis in the treatment of paraneoplastic cerebellar degeneration]. Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti. vol 58. issue 1. 2004-05-21. PMID:15125396. |
anti-yo antibodies are directed against purkinje cell antigens and occur in patients with cerebellar degeneration who have breast cancer or gynecologic tumors. |
2004-05-21 |
2023-08-12 |
Not clear |
| Jiankai Luo, Ullrich Treubert-Zimmermann, Christoph Redie. Cadherins guide migrating Purkinje cells to specific parasagittal domains during cerebellar development. Molecular and cellular neurosciences. vol 25. issue 1. 2004-05-19. PMID:14962747. |
several cadherins are expressed in parasagittal purkinje cell domains, which can be defined by their afferent and efferent connectivity in the developing and mature cerebellum. |
2004-05-19 |
2023-08-12 |
chicken |
| O Natt, T Watanabe, S Boretius, J Frahm, T Michaeli. Magnetization transfer MRI of mouse brain reveals areas of high neural density. Magnetic resonance imaging. vol 21. issue 10. 2004-05-14. PMID:14725918. |
examples include the purkinje cell layer and the granular cell layer in the mouse cerebellum as well as the delineation of the ca3 subfield of the hippocampus relative to surrounding hippocampal gray matter and white matter tracts such as the hippocampal fimbria. |
2004-05-14 |
2023-08-12 |
mouse |
| Norihiko Murai, Jun Tsuji, Juichi Ito, Masayoshi Mishina, Tomoo Hiran. Vestibular compensation in glutamate receptor delta-2 subunit knockout mice: dynamic property of vestibulo-ocular reflex. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 261. issue 2. 2004-05-11. PMID:12851830. |
delta-2 knock-out mice have defects in purkinje cell synapse formation, as well as cerebellar long- term depression. |
2004-05-11 |
2023-08-12 |
mouse |
| Lucy Anderson, Daniela Rossi, Jackie Linehan, Sebastian Brandner, Charles Weissman. Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 10. 2004-05-05. PMID:15007176. |
however, ubiquitous dpl overexpression in the brain of prp knockout mice correlated with ataxia and purkinje cell degeneration in the cerebellum. |
2004-05-05 |
2023-08-12 |
mouse |
| N M Ellinwood, P Wang, T Skeen, N J H Sharp, M Cesta, S Decker, N J Edwards, I Bublot, J N Thompson, W Bush, E Hardam, M E Haskins, U Gige. A model of mucopolysaccharidosis IIIB (Sanfilippo syndrome type IIIB): N-acetyl-alpha-D-glucosaminidase deficiency in Schipperke dogs. Journal of inherited metabolic disease. vol 26. issue 5. 2004-04-30. PMID:14518829. |
pathology of the brain included severe cerebellar atrophy, purkinje cell loss, and cytoplasmic vacuolation in neurons and perithelial cells throughout the central nervous system. |
2004-04-30 |
2023-08-12 |
mouse |
| Yasuko Kitao, Kouichi Hashimoto, Tomohiro Matsuyama, Hiroyuki Iso, Takeshi Tamatani, Osamu Hori, David M Stern, Masanobu Kano, Kentaro Ozawa, Satoshi Ogaw. ORP150/HSP12A regulates Purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 6. 2004-04-26. PMID:14960622. |
orp150/hsp12a regulates purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development. |
2004-04-26 |
2023-08-12 |
mouse |